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Entry version 129 (07 Oct 2020)
Sequence version 1 (01 Dec 2001)
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Protein

Mdm2-binding protein

Gene

MTBP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Growth arrest, Ubl conjugation pathway

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96DY7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mdm2-binding protein
Short name:
hMTBP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTBP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000172167.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7417, MTBP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605927, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96DY7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
27085

Open Targets

More...
OpenTargetsi
ENSG00000172167

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31224

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96DY7, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTBP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74731509

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003237451 – 904Mdm2-binding proteinAdd BLAST904

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei597PhosphoserineCombined sources1
Modified residuei639PhosphoserineCombined sources1
Modified residuei703PhosphoserineCombined sources1
Modified residuei707PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96DY7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96DY7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96DY7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96DY7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96DY7

PeptideAtlas

More...
PeptideAtlasi
Q96DY7

PRoteomics IDEntifications database

More...
PRIDEi
Q96DY7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
5205
76343 [Q96DY7-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96DY7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96DY7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000172167, Expressed in intestine and 131 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96DY7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96DY7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000172167, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with MDM2.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
117988, 26 interactors

Protein interaction database and analysis system

More...
IntActi
Q96DY7, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000303398

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96DY7, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni521 – 904Interaction with MDM2By similarityAdd BLAST384

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MTBP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502RGBH, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003305

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_923010_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96DY7

Identification of Orthologs from Complete Genome Data

More...
OMAi
WEEIHFG

Database of Orthologous Groups

More...
OrthoDBi
1334548at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96DY7

TreeFam database of animal gene trees

More...
TreeFami
TF331503

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039061, MTBP
IPR029418, MTBP_C
IPR029420, MTBP_central
IPR029421, MTBP_N

The PANTHER Classification System

More...
PANTHERi
PTHR14382, PTHR14382, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14920, MTBP_C, 1 hit
PF14919, MTBP_mid, 1 hit
PF14918, MTBP_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96DY7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDRYLLLVIW GEGKFPSAAS REAEHGPEVS SGEGTENQPD FTAANVYHLL
60 70 80 90 100
KRSISASINP EDSTFPACSV GGIPGSKKWF FAVQAIYGFY QFCSSDWQEI
110 120 130 140 150
HFDTEKDKIE DVLQTNIEEC LGAVECFEEE DSNSRESLSL ADLYEEAAEN
160 170 180 190 200
LHQLSDKLPA PGRAMVDIIL LLSDKDPPKL KDYLPTVGAL KHLREWYSAK
210 220 230 240 250
ITIAGNHCEI NCQKIAEYLS ANVVSLEDLR NVIDSKELWR GKIQIWERKF
260 270 280 290 300
GFEISFPEFC LKGVTLKNFS TSNLNTDFLA KKIIPSKDKN ILPKVFHYYG
310 320 330 340 350
PALEFVQMIK LSDLPSCYMS DIEFELGLTN STKQNSVLLL EQISSLCSKV
360 370 380 390 400
GALFVLPCTI SNILIPPPNQ LSSRKWKEYI AKKPKTISVP DVEVKGECSS
410 420 430 440 450
YYLLLQGNGN RRCKATLIHS ANQINGSFAL NLIHGKMKTK TEEAKLSFPF
460 470 480 490 500
DLLSLPHFSG EQIVQREKQL ANVQVLALEE CLKRRKLAKQ PETVSVAELK
510 520 530 540 550
SLLVLTRKHF LDYFDAVIPK MILRKMDKIK TFNILNDFSP VEPNSSSLME
560 570 580 590 600
TNPLEWPERH VLQNLETFEK TKQKMRTGSL PHSSEQLLGH KEGPRDSITL
610 620 630 640 650
LDAKELLKYF TSDGLPIGDL QPLPIQKGEK TFVLTPELSP GKLQVLPFEK
660 670 680 690 700
ASVCHYHGIE YCLDDRKALE RDGGFSELQS RLIRYETQTT CTRESFPVPT
710 720 730 740 750
VLSPLPSPVV SSDPGSVPDG EVLQNELRTE VSRLKRRSKD LNCLYPRKRL
760 770 780 790 800
VKSESSESLL SQTTGNSNHY HHHVTSRKPQ TERSLPVTCP LVPIPSCETP
810 820 830 840 850
KLATKTSSGQ KSMHESKTSR QIKESRSQKH TRILKEVVTE TLKKHSITET
860 870 880 890 900
HECFTACSQR LFEISKFYLK DLKTSRGLFE EMKKTANNNA VQVIDWVLEK

TSKK
Length:904
Mass (Da):102,193
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i753DF4A98AB62E4F
GO
Isoform 2 (identifier: Q96DY7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     326-329: LGLT → FTED
     330-904: Missing.

Show »
Length:329
Mass (Da):37,253
Checksum:iAB75C6597A082DAC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YB28H0YB28_HUMAN
Mdm2-binding protein
MTBP
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB13965 differs from that shown. Probable cloning artifact. May result from internal priming due to genomic poly-A tracts.Curated
The sequence EAW92007 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_056108326 – 329LGLT → FTED in isoform 2. 1 Publication4
Alternative sequenceiVSP_056109330 – 904Missing in isoform 2. 1 PublicationAdd BLAST575

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK022122 mRNA Translation: BAB13965.1 Sequence problems.
AK300762 mRNA Translation: BAG62427.1
AC105142 Genomic DNA No translation available.
AC107877 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW92006.1
CH471060 Genomic DNA Translation: EAW92007.1 Sequence problems.
BC013136 mRNA Translation: AAH13136.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6333.1 [Q96DY7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_071328.2, NM_022045.4 [Q96DY7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000305949; ENSP00000303398; ENSG00000172167 [Q96DY7-1]
ENST00000523373; ENSP00000430771; ENSG00000172167 [Q96DY7-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27085

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:27085

UCSC genome browser

More...
UCSCi
uc003ypc.3, human [Q96DY7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022122 mRNA Translation: BAB13965.1 Sequence problems.
AK300762 mRNA Translation: BAG62427.1
AC105142 Genomic DNA No translation available.
AC107877 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW92006.1
CH471060 Genomic DNA Translation: EAW92007.1 Sequence problems.
BC013136 mRNA Translation: AAH13136.1
CCDSiCCDS6333.1 [Q96DY7-1]
RefSeqiNP_071328.2, NM_022045.4 [Q96DY7-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi117988, 26 interactors
IntActiQ96DY7, 4 interactors
STRINGi9606.ENSP00000303398

PTM databases

iPTMnetiQ96DY7
PhosphoSitePlusiQ96DY7

Polymorphism and mutation databases

BioMutaiMTBP
DMDMi74731509

Proteomic databases

EPDiQ96DY7
jPOSTiQ96DY7
MassIVEiQ96DY7
MaxQBiQ96DY7
PaxDbiQ96DY7
PeptideAtlasiQ96DY7
PRIDEiQ96DY7
ProteomicsDBi5205
76343 [Q96DY7-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
13747, 261 antibodies

The DNASU plasmid repository

More...
DNASUi
27085

Genome annotation databases

EnsembliENST00000305949; ENSP00000303398; ENSG00000172167 [Q96DY7-1]
ENST00000523373; ENSP00000430771; ENSG00000172167 [Q96DY7-3]
GeneIDi27085
KEGGihsa:27085
UCSCiuc003ypc.3, human [Q96DY7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27085
DisGeNETi27085
EuPathDBiHostDB:ENSG00000172167.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTBP
HGNCiHGNC:7417, MTBP
HPAiENSG00000172167, Low tissue specificity
MIMi605927, gene
neXtProtiNX_Q96DY7
OpenTargetsiENSG00000172167
PharmGKBiPA31224

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502RGBH, Eukaryota
GeneTreeiENSGT00390000003305
HOGENOMiCLU_923010_0_0_1
InParanoidiQ96DY7
OMAiWEEIHFG
OrthoDBi1334548at2759
PhylomeDBiQ96DY7
TreeFamiTF331503

Enzyme and pathway databases

PathwayCommonsiQ96DY7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
27085, 695 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MTBP, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
27085
PharosiQ96DY7, Tbio

Protein Ontology

More...
PROi
PR:Q96DY7
RNActiQ96DY7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000172167, Expressed in intestine and 131 other tissues
ExpressionAtlasiQ96DY7, baseline and differential
GenevisibleiQ96DY7, HS

Family and domain databases

InterProiView protein in InterPro
IPR039061, MTBP
IPR029418, MTBP_C
IPR029420, MTBP_central
IPR029421, MTBP_N
PANTHERiPTHR14382, PTHR14382, 1 hit
PfamiView protein in Pfam
PF14920, MTBP_C, 1 hit
PF14919, MTBP_mid, 1 hit
PF14918, MTBP_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTBP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96DY7
Secondary accession number(s): B4DUR5, Q9HA89
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: December 1, 2001
Last modified: October 7, 2020
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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