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UniProtKB - Q96DS0 (Q96DS0_HUMAN)
Protein
Submitted name:
MDM2 variant FB55
Gene
MDM2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- negative regulation of apoptotic process Source: InterPro
- negative regulation of transcription by RNA polymerase II Source: InterPro
- protein ubiquitination Source: InterPro
- regulation of cell cycle Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: MDM2 variant FB55Imported |
Gene namesi | Name:MDM2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Structurei
Family & Domainsi
Family and domain databases
Gene3Di | 1.10.245.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR015459, MDM2_E3_ligase IPR016495, p53_neg-reg_MDM_2/4 IPR036885, SWIB_MDM2_dom_sf IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR13844:SF15, PTHR13844:SF15, 1 hit |
PIRSFi | PIRSF006748, p53_MDM_2/4, 3 hits |
SUPFAMi | SSF47592, SSF47592, 1 hit |
i Sequence
Sequence statusi: Complete.
Q96DS0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCNTNMSVPT DGAVTTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM
60 70 80 90 100
KEDLDAGVSE HSGDWLDQDS VSDQFSVEFE VESLDSEDYS LSEEGQELSD
110 120 130 140 150
EDDEVYQVTV YQAGESDTDS FEEDPEISLA DYWKCLKKRN KPCPVCRQPI
QMIVLTYFP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF385327 mRNA Translation: AAL13247.1 |
RefSeqi | NP_001138812.1, NM_001145340.2 NP_001265391.1, NM_001278462.1 |
Genome annotation databases
GeneIDi | 4193 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF385327 mRNA Translation: AAL13247.1 |
RefSeqi | NP_001138812.1, NM_001145340.2 NP_001265391.1, NM_001278462.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q96DS0 |
Protocols and materials databases
DNASUi | 4193 |
Genome annotation databases
GeneIDi | 4193 |
Organism-specific databases
CTDi | 4193 |
Miscellaneous databases
BioGRID-ORCSi | 4193, 210 hits in 1135 CRISPR screens |
ChiTaRSi | MDM2, human |
GenomeRNAii | 4193 |
Family and domain databases
Gene3Di | 1.10.245.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR015459, MDM2_E3_ligase IPR016495, p53_neg-reg_MDM_2/4 IPR036885, SWIB_MDM2_dom_sf IPR013083, Znf_RING/FYVE/PHD |
PANTHERi | PTHR13844:SF15, PTHR13844:SF15, 1 hit |
PIRSFi | PIRSF006748, p53_MDM_2/4, 3 hits |
SUPFAMi | SSF47592, SSF47592, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q96DS0_HUMAN | |
Accessioni | Q96DS0Primary (citable) accession number: Q96DS0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 1, 2001 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |