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Entry version 156 (17 Jun 2020)
Sequence version 2 (02 Nov 2010)
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Protein

FXYD domain-containing ion transport regulator 5

Gene

FXYD5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel
Biological processIon transport, Transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.27.3.1 the phospholemman (plm) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
FXYD domain-containing ion transport regulator 5
Alternative name(s):
Dysadherin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FXYD5
Synonyms:DYSAD, IWU1
ORF Names:HSPC113, UNQ2561/PRO6241
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000089327.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4029 FXYD5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606669 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96DB9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 145ExtracellularSequence analysisAdd BLAST124
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei146 – 164HelicalSequence analysisAdd BLAST19
Topological domaini165 – 178CytoplasmicSequence analysisAdd BLAST14

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
53827

Open Targets

More...
OpenTargetsi
ENSG00000089327

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28445

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96DB9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FXYD5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033386

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001036922 – 178FXYD domain-containing ion transport regulator 5Add BLAST157

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96DB9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96DB9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96DB9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96DB9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96DB9

PeptideAtlas

More...
PeptideAtlasi
Q96DB9

PRoteomics IDEntifications database

More...
PRIDEi
Q96DB9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
76270 [Q96DB9-1]
76271 [Q96DB9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96DB9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96DB9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q96DB9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000089327 Expressed in ectocervix and 189 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96DB9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96DB9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000089327 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
119800, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q96DB9, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344254

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96DB9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96DB9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FXYD family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JCU8 Eukaryota
ENOG4111E7R LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00990000203844

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_109413_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96DB9

KEGG Orthology (KO)

More...
KOi
K13362

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96DB9

TreeFam database of animal gene trees

More...
TreeFami
TF338182

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000272 Ion-transport_regulator_FXYD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02038 ATP1G1_PLM_MAT8, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01310 FXYD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96DB9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSPSGRLCLL TIVGLILPTR GQTLKDTTSS SSADSTIMDI QVPTRAPDAV
60 70 80 90 100
YTELQPTSPT PTWPADETPQ PQTQTQQLEG TDGPLVTDPE THKSTKAAHP
110 120 130 140 150
TDDTTTLSER PSPSTDVQTD PQTLKPSGFH EDDPFFYDEH TLRKRGLLVA
160 170
AVLFITGIII LTSGKCRQLS RLCRNRCR
Length:178
Mass (Da):19,472
Last modified:November 2, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7429C04838B75AA1
GO
Isoform 2 (identifier: Q96DB9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: MSPSGRLCLL...DPETHKSTKA → MQTLSNIPCFCLHGSLLPSTDLATLS

Show »
Length:107
Mass (Da):11,888
Checksum:i121958DF3334315C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5H4X8F5H4X8_HUMAN
FXYD domain-containing ion transpor...
FXYD5
194Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJH6K7EJH6_HUMAN
FXYD domain-containing ion transpor...
FXYD5
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8MVG1A8MVG1_HUMAN
FXYD domain-containing ion transpor...
FXYD5
96Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ER99K7ER99_HUMAN
FXYD domain-containing ion transpor...
FXYD5
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti140 – 141HT → SH in AAF29077 (PubMed:11042152).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01234935S → A. Corresponds to variant dbSNP:rs1688005Ensembl.1
Natural variantiVAR_027959176R → H5 PublicationsCorresponds to variant dbSNP:rs12110Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0015841 – 97MSPSG…KSTKA → MQTLSNIPCFCLHGSLLPST DLATLS in isoform 2. 1 PublicationAdd BLAST97

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF177940 mRNA Translation: AAG09301.1
AB072911 mRNA Translation: BAB83766.1
AF161462 mRNA Translation: AAF29077.1
AY358991 mRNA Translation: AAQ89350.1
BT007343 mRNA Translation: AAP36007.1
AC002390 Genomic DNA No translation available.
AC020907 Genomic DNA No translation available.
BC009642 mRNA Translation: AAH09642.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12447.1 [Q96DB9-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001158077.1, NM_001164605.1 [Q96DB9-1]
NP_001307842.1, NM_001320913.1
NP_054883.3, NM_014164.5 [Q96DB9-1]
NP_659003.1, NM_144779.2 [Q96DB9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000342879; ENSP00000344254; ENSG00000089327 [Q96DB9-1]
ENST00000392217; ENSP00000376051; ENSG00000089327 [Q96DB9-2]
ENST00000392219; ENSP00000376053; ENSG00000089327 [Q96DB9-1]
ENST00000423817; ENSP00000393848; ENSG00000089327 [Q96DB9-1]
ENST00000541435; ENSP00000443390; ENSG00000089327 [Q96DB9-1]
ENST00000590686; ENSP00000465667; ENSG00000089327 [Q96DB9-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
53827

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:53827

UCSC genome browser

More...
UCSCi
uc002nyg.3 human [Q96DB9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF177940 mRNA Translation: AAG09301.1
AB072911 mRNA Translation: BAB83766.1
AF161462 mRNA Translation: AAF29077.1
AY358991 mRNA Translation: AAQ89350.1
BT007343 mRNA Translation: AAP36007.1
AC002390 Genomic DNA No translation available.
AC020907 Genomic DNA No translation available.
BC009642 mRNA Translation: AAH09642.1
CCDSiCCDS12447.1 [Q96DB9-1]
RefSeqiNP_001158077.1, NM_001164605.1 [Q96DB9-1]
NP_001307842.1, NM_001320913.1
NP_054883.3, NM_014164.5 [Q96DB9-1]
NP_659003.1, NM_144779.2 [Q96DB9-1]

3D structure databases

SMRiQ96DB9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi119800, 1 interactor
IntActiQ96DB9, 1 interactor
STRINGi9606.ENSP00000344254

Protein family/group databases

TCDBi1.A.27.3.1 the phospholemman (plm) family

PTM databases

iPTMnetiQ96DB9
PhosphoSitePlusiQ96DB9
SwissPalmiQ96DB9

Polymorphism and mutation databases

BioMutaiFXYD5
DMDMi311033386

Proteomic databases

EPDiQ96DB9
jPOSTiQ96DB9
MassIVEiQ96DB9
MaxQBiQ96DB9
PaxDbiQ96DB9
PeptideAtlasiQ96DB9
PRIDEiQ96DB9
ProteomicsDBi76270 [Q96DB9-1]
76271 [Q96DB9-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2277 201 antibodies

The DNASU plasmid repository

More...
DNASUi
53827

Genome annotation databases

EnsembliENST00000342879; ENSP00000344254; ENSG00000089327 [Q96DB9-1]
ENST00000392217; ENSP00000376051; ENSG00000089327 [Q96DB9-2]
ENST00000392219; ENSP00000376053; ENSG00000089327 [Q96DB9-1]
ENST00000423817; ENSP00000393848; ENSG00000089327 [Q96DB9-1]
ENST00000541435; ENSP00000443390; ENSG00000089327 [Q96DB9-1]
ENST00000590686; ENSP00000465667; ENSG00000089327 [Q96DB9-1]
GeneIDi53827
KEGGihsa:53827
UCSCiuc002nyg.3 human [Q96DB9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
53827
DisGeNETi53827
EuPathDBiHostDB:ENSG00000089327.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FXYD5
HGNCiHGNC:4029 FXYD5
HPAiENSG00000089327 Low tissue specificity
MIMi606669 gene
neXtProtiNX_Q96DB9
OpenTargetsiENSG00000089327
PharmGKBiPA28445

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JCU8 Eukaryota
ENOG4111E7R LUCA
GeneTreeiENSGT00990000203844
HOGENOMiCLU_109413_0_0_1
InParanoidiQ96DB9
KOiK13362
PhylomeDBiQ96DB9
TreeFamiTF338182

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
53827 5 hits in 781 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FXYD5 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
FXYD5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
53827
PharosiQ96DB9 Tbio

Protein Ontology

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PROi
PR:Q96DB9
RNActiQ96DB9 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000089327 Expressed in ectocervix and 189 other tissues
ExpressionAtlasiQ96DB9 baseline and differential
GenevisibleiQ96DB9 HS

Family and domain databases

InterProiView protein in InterPro
IPR000272 Ion-transport_regulator_FXYD
PfamiView protein in Pfam
PF02038 ATP1G1_PLM_MAT8, 1 hit
PROSITEiView protein in PROSITE
PS01310 FXYD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFXYD5_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96DB9
Secondary accession number(s): B7WNZ8
, Q6UW44, Q9HC34, Q9P039
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: November 2, 2010
Last modified: June 17, 2020
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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