Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q96CN9 (GCC1_HUMAN)

Entry version 155 (10 Feb 2021)
Sequence version 1 (01 Dec 2001)
Previous versions | rss
Add a publicationFeedback
Protein

GRIP and coiled-coil domain-containing protein 1

Gene

GCC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably involved in maintaining Golgi structure.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96CN9

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-6811440, Retrograde transport at the Trans-Golgi-Network

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q96CN9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GRIP and coiled-coil domain-containing protein 1
Alternative name(s):
Golgi coiled-coil protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GCC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:19095, GCC1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607418, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96CN9

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000179562.2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		79571

Open Targets

More...OpenTargetsi		ENSG00000179562

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38796

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96CN9, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		GCC1

Domain mapping of disease mutations (DMDM)

More...DMDMi		32699595

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001900721 – 775GRIP and coiled-coil domain-containing protein 1Add BLAST775

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96CN9

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96CN9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96CN9

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96CN9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96CN9

PeptideAtlas

More...PeptideAtlasi		Q96CN9

PRoteomics IDEntifications database

More...PRIDEi		Q96CN9

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		76200

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96CN9

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q96CN9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96CN9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000179562, Expressed in testis and 223 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96CN9, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96CN9, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000179562, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q96CN9
With#Exp.IntAct
ABI2 [Q9NYB9]4EBI-746252,EBI-743598
ATF4 [P18848]6EBI-746252,EBI-492498
BIRC2 [Q13490]6EBI-746252,EBI-514538
C1orf94 [Q6P1W5]3EBI-746252,EBI-946029
CEP57 [Q86XR8]5EBI-746252,EBI-308614
CEP57 - isoform 3 [Q86XR8-3]3EBI-746252,EBI-11752486
CEP70 [Q8NHQ1]6EBI-746252,EBI-739624
DISC1 - isoform 2 [Q9NRI5-2]3EBI-746252,EBI-11988027
DNAJA3 - isoform 2 [Q96EY1-2]3EBI-746252,EBI-3952284
FAM83A [Q86UY5]3EBI-746252,EBI-1384254
FBXO28 [Q9NVF7]3EBI-746252,EBI-740282
FIGNL1 [Q6PIW4]3EBI-746252,EBI-8468390
FOSL1 [P15407]3EBI-746252,EBI-744510
GAS8 [O95995]3EBI-746252,EBI-1052570
GLI1 [P08151]3EBI-746252,EBI-308084
GOLGA2 [Q08379]6EBI-746252,EBI-618309
HDX [Q7Z353]3EBI-746252,EBI-1052734
ICA1L - isoform 2 [Q8NDH6-2]3EBI-746252,EBI-12141931
KATNAL1 [Q9BW62]3EBI-746252,EBI-743591
KDM1A [O60341]3EBI-746252,EBI-710124
KIAA0753 [Q2KHM9]3EBI-746252,EBI-2805604
KIF5B [P33176]3EBI-746252,EBI-355878
LCA5 [Q86VQ0]3EBI-746252,EBI-6658186
LZTS2 [Q9BRK4]3EBI-746252,EBI-741037
MCRS1 [Q96EZ8]3EBI-746252,EBI-348259
MED4 [Q9NPJ6]3EBI-746252,EBI-394607
MEOX1 [P50221]3EBI-746252,EBI-2864512
MID2 - isoform 2 [Q9UJV3-2]3EBI-746252,EBI-10172526
NAB2 [Q15742]3EBI-746252,EBI-8641936
NAV1 - isoform 3 [Q8NEY1-3]3EBI-746252,EBI-11953718
NAV1 - isoform 4 [Q8NEY1-4]3EBI-746252,EBI-10270828
NECAB2 - isoform 2 [Q7Z6G3-2]3EBI-746252,EBI-10172876
OIP5 [O43482]3EBI-746252,EBI-536879
PAK5 [Q9P286]3EBI-746252,EBI-741896
PPP1R18 [Q6NYC8]3EBI-746252,EBI-2557469
PPP1R27 [Q86WC6]3EBI-746252,EBI-5235602
PRPF18 [Q99633]3EBI-746252,EBI-2798416
RUNX1 - isoform AML-1G [Q01196-8]3EBI-746252,EBI-12001422
TFIP11 [Q9UBB9]3EBI-746252,EBI-1105213
TLE5 - isoform 2 [Q08117-2]3EBI-746252,EBI-11741437
TP53BP2 [Q05BL1]3EBI-746252,EBI-11952721
TRIM29 [Q14134]2EBI-746252,EBI-702370
TRIM50 [Q86XT4]3EBI-746252,EBI-9867283
UTP14C [Q5TAP6]3EBI-746252,EBI-11737646
XIAP [P98170]3EBI-746252,EBI-517127
ZC4H2 [Q9NQZ6]3EBI-746252,EBI-747993
ZFP90 [Q8TF47]3EBI-746252,EBI-11419867
ZNF276 - isoform 2 [Q8N554-2]3EBI-746252,EBI-10265849

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122718, 94 interactors

Protein interaction database and analysis system

More...IntActi		Q96CN9, 89 interactors

Molecular INTeraction database

More...MINTi		Q96CN9

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000318821

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96CN9, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96CN9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini713 – 763GRIPPROSITE-ProRule annotationAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili13 – 61Sequence analysisAdd BLAST49
Coiled coili153 – 763Sequence analysisAdd BLAST611

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Extended rod-like protein with coiled-coil domains.

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QQ2S, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153772

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_020679_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96CN9

Identification of Orthologs from Complete Genome Data

More...OMAi		FQADKKQ

Database of Orthologous Groups

More...OrthoDBi		979102at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96CN9

TreeFam database of animal gene trees

More...TreeFami		TF324186

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000237, GRIP_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01465, GRIP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00755, Grip, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50913, GRIP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96CN9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKFGMNFGG GPSKKDLLET IETQKKQLLQ YQARLKDVVR AYKSLLKEKE 
        60         70         80         90        100
ALEASIKVLS VSHEADVGLA GVQLPGLTFP DSVDDRCSTH SEDSTGTATS 
       110        120        130        140        150
LDTAASLTST KGEFGVEDDR PARGPPPPKS EEASWSESGV SSSSGDGPFA 
       160        170        180        190        200
GGEVDKRLHQ LKTQLATLTS SLATVTQEKS RMEASYLADK KKMKQDLEDA 
       210        220        230        240        250
SNKAEEERAR LEGELKGLQE QIAETKARLI TQQHDRAQEQ SDHALMLREL 
       260        270        280        290        300
QKLLQEERTQ RQDLELRLEE TREALAGRAY AAEQMEGFEL QTKQLTREVE 
       310        320        330        340        350
ELKSELQAIR DEKNQPDPRL QELQEEAARL KSHFQAQLQQ EMRKTALAED 
       360        370        380        390        400
QLRQQSQVEE QRVAALENQI SEVSELLGTY EKAKQKDQLA IQKLKERILQ 
       410        420        430        440        450
LDLENKTLAL AASSRSPLDS HGEESSLDVN VLKDKMEKLK RLLQVAARKS 
       460        470        480        490        500
QVTLDVEKLC DLEIMPSSEA ADGEKATALY YQQELKQLKE EFERYKMRAQ 
       510        520        530        540        550
VVLKSKNTKD GNLGKELEAA QEQLAELKEK YISLRLSCEE LEHQHQQEAD 
       560        570        580        590        600
DWKQELARLQ QLHRQELERC QLDFRDRTLK LEEELHKQRD RALAVLTEKD 
       610        620        630        640        650
LELEQLRSVA LASGLPGRRS PVGGGGPGDP ADTSSSDSLT QALQLAAANE 
       660        670        680        690        700
PTFFLYAEQL ARKEVEITSL RKQKHRLEVE VHQLQDRLLE EGERHREEVA 
       710        720        730        740        750
ALQSHIEKNI RDQSREGANL EYLKNIIYRF LTLPDSLGRQ QTLTAILTIL 
       760        770 
HFSPEEKQVI MRLPTSASWW PSGKR
Length:775
Mass (Da):87,811
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED72FF26BDF8DAD6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH08902 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated
The sequence BAB15218 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02190286R → W. Corresponds to variant dbSNP:rs17151044Ensembl.1
Natural variantiVAR_02015787C → W. Corresponds to variant dbSNP:rs2285348Ensembl.1
Natural variantiVAR_049259122A → V. Corresponds to variant dbSNP:rs35322201Ensembl.1
Natural variantiVAR_049260262Q → R. Corresponds to variant dbSNP:rs35390108Ensembl.1
Natural variantiVAR_049261274A → T. Corresponds to variant dbSNP:rs34887879Ensembl.1
Natural variantiVAR_049262618R → C. Corresponds to variant dbSNP:rs34883586Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF525417 mRNA Translation: AAM91948.1
BC008902 mRNA Translation: AAH08902.2 Sequence problems.
BC014100 mRNA Translation: AAH14100.1
BC078665 mRNA Translation: AAH78665.1
AK025688 mRNA Translation: BAB15218.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS5796.1

NCBI Reference Sequences

More...RefSeqi		NP_078799.2, NM_024523.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000321407; ENSP00000318821; ENSG00000179562

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79571

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79571

UCSC genome browser

More...UCSCi		uc003vma.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF525417 mRNA Translation: AAM91948.1
BC008902 mRNA Translation: AAH08902.2 Sequence problems.
BC014100 mRNA Translation: AAH14100.1
BC078665 mRNA Translation: AAH78665.1
AK025688 mRNA Translation: BAB15218.1 Different initiation.
CCDSiCCDS5796.1
RefSeqiNP_078799.2, NM_024523.5

3D structure databases

SMRiQ96CN9
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122718, 94 interactors
IntActiQ96CN9, 89 interactors
MINTiQ96CN9
STRINGi9606.ENSP00000318821

PTM databases

iPTMnetiQ96CN9
MetOSiteiQ96CN9
PhosphoSitePlusiQ96CN9

Genetic variation databases

BioMutaiGCC1
DMDMi32699595

Proteomic databases

EPDiQ96CN9
jPOSTiQ96CN9
MassIVEiQ96CN9
MaxQBiQ96CN9
PaxDbiQ96CN9
PeptideAtlasiQ96CN9
PRIDEiQ96CN9
ProteomicsDBi76200

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		17726, 152 antibodies

The DNASU plasmid repository

More...DNASUi		79571

Genome annotation databases

EnsembliENST00000321407; ENSP00000318821; ENSG00000179562
GeneIDi79571
KEGGihsa:79571
UCSCiuc003vma.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79571
DisGeNETi79571

GeneCards: human genes, protein and diseases

More...GeneCardsi		GCC1
HGNCiHGNC:19095, GCC1
HPAiENSG00000179562, Low tissue specificity
MIMi607418, gene
neXtProtiNX_Q96CN9
OpenTargetsiENSG00000179562
PharmGKBiPA38796
VEuPathDBiHostDB:ENSG00000179562.2

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QQ2S, Eukaryota
GeneTreeiENSGT00940000153772
HOGENOMiCLU_020679_0_0_1
InParanoidiQ96CN9
OMAiFQADKKQ
OrthoDBi979102at2759
PhylomeDBiQ96CN9
TreeFamiTF324186

Enzyme and pathway databases

PathwayCommonsiQ96CN9
ReactomeiR-HSA-6811440, Retrograde transport at the Trans-Golgi-Network
SIGNORiQ96CN9

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79571, 5 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		GCC1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		GCC1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79571
PharosiQ96CN9, Tbio

Protein Ontology

More...PROi		PR:Q96CN9
RNActiQ96CN9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000179562, Expressed in testis and 223 other tissues
ExpressionAtlasiQ96CN9, baseline and differential
GenevisibleiQ96CN9, HS

Family and domain databases

InterProiView protein in InterPro
IPR000237, GRIP_dom
PfamiView protein in Pfam
PF01465, GRIP, 1 hit
SMARTiView protein in SMART
SM00755, Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913, GRIP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGCC1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96CN9
Secondary accession number(s): Q9H6N7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: December 1, 2001
Last modified: February 10, 2021
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with genetic variants
    List of human entries with genetic variants
  2. Human variants curated from literature reports
    Index of human variants curated from literature reports
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again