PPCDC

Functionⁱ

Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.2 Publications

Catalytic activityⁱ

N-((R)-4'-phosphopantothenoyl)-L-cysteine = pantotheine 4'-phosphate + CO₂.

Cofactorⁱ

FMNNote: Binds 1 FMN per subunit.

Pathwayⁱ: coenzyme A biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes CoA from (R)-pantothenate.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:

Pantothenate kinase 1 (PANK1), Pantothenate kinase 3 (PANK3), Pantothenate kinase 2, mitochondrial (PANK2), Pantothenate kinase 4 (PANK4), Pantothenate kinase 4, Pantothenate kinase 4, Pantothenate kinase 4 (PANK4)
Phosphopantothenate--cysteine ligase (PPCS)
Phosphopantothenoylcysteine decarboxylase (PPCDC)
Bifunctional coenzyme A synthase (COASY)
Bifunctional coenzyme A synthase (COASY)

This subpathway is part of the pathway coenzyme A biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CoA from (R)-pantothenate, the pathway coenzyme A biosynthesis and in Cofactor biosynthesis.

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	59	FMN1 Publication	1
Binding siteⁱ	140	SubstrateBy similarity	1
Active siteⁱ	173	Proton donor	1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	104 – 107	FMN1 Publication		4

GO - Molecular functionⁱ

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

coenzyme A biosynthetic process
Source: UniProtKB
Inferred from direct assayⁱ
- 11923312
coenzyme biosynthetic process Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Decarboxylase, Lyase
Biological process	Coenzyme A biosynthesis
Ligand	Flavoprotein, FMN

Enzyme and pathway databases

BioCycⁱ	MetaCyc:HS13735-MONOMER
Reactomeⁱ	R-HSA-196783 Coenzyme A biosynthesis
SABIO-RKⁱ	Q96CD2
UniPathwayⁱ	UPA00241;UER00354

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Phosphopantothenoylcysteine decarboxylase (EC:4.1.1.36) Short name: PPC-DC Alternative name(s): CoaC
Gene namesⁱ	Name:PPCDC Synonyms:COAC ORF Names:MDS018, UNQ9365/PRO34154
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 15

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000138621.11
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:28107 PPCDC
MIMⁱ	609854 gene
neXtProtⁱ	NX_Q96CD2

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	60490
Open Targets More...OpenTargetsⁱ	ENSG00000138621
PharmGKBⁱ	PA142671157

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB03738 Pantothenoylaminoethenethiol DB03247 Riboflavin Monophosphate

DrugBankⁱ

DB03738 Pantothenoylaminoethenethiol
DB03247 Riboflavin Monophosphate

Polymorphism and mutation databases

BioMutaⁱ	PPCDC
DMDMⁱ	296434457

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000182030	1 – 204	Phosphopantothenoylcysteine decarboxylaseAdd BLAST		204

Proteomic databases

EPDⁱ	Q96CD2
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96CD2
PaxDbⁱ	Q96CD2
PeptideAtlas More...PeptideAtlasⁱ	Q96CD2
PRIDEⁱ	Q96CD2
ProteomicsDBⁱ	76180 76181 [Q96CD2-2]

PTM databases

iPTMnetⁱ	Q96CD2
PhosphoSitePlusⁱ	Q96CD2

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000138621 Expressed in 170 organ(s), highest expression level in blood
CleanExⁱ	HS_PPCDC
ExpressionAtlasⁱ	Q96CD2 baseline and differential
Genevisibleⁱ	Q96CD2 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA045667

HPAⁱ

HPA045667

Interactionⁱ

Subunit structureⁱ

Homotrimer.Curated

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
itself		4	EBI-724333,EBI-724333
FOXR1	Q6PIV2	5	EBI-724333,EBI-10253815
PPIG	Q13427	3	EBI-724333,EBI-396072
SREK1IP1	Q8N9Q2	3	EBI-724333,EBI-10268630
TXN2	Q99757	5	EBI-724333,EBI-2932492
WDYHV1	Q96HA8	5	EBI-724333,EBI-741158
ZNF232	Q9UNY5	5	EBI-724333,EBI-749023

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 25416956
- 26514574

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	121921, 11 interactors
IntActⁱ	Q96CD2, 16 interactors
Molecular INTeraction database More...MINTⁱ	Q96CD2
STRINGⁱ	9606.ENSP00000343190

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	16 – 24	Combined sources	9
Helixⁱ	28 – 31	Combined sources	4
Helixⁱ	33 – 40	Combined sources	8
Beta strandⁱ	46 – 52	Combined sources	7
Helixⁱ	55 – 58	Combined sources	4
Helixⁱ	62 – 64	Combined sources	3
Helixⁱ	72 – 77	Combined sources	6
Helixⁱ	87 – 92	Combined sources	6
Beta strandⁱ	96 – 103	Combined sources	8
Helixⁱ	105 – 112	Combined sources	8
Helixⁱ	119 – 125	Combined sources	7
Beta strandⁱ	135 – 137	Combined sources	3
Helixⁱ	141 – 144	Combined sources	4
Helixⁱ	149 – 157	Combined sources	9
Helixⁱ	186 – 191	Combined sources	6

Show more details

3D structure databases

ProteinModelPortalⁱ	Q96CD2
SMRⁱ	Q96CD2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q96CD2

EvolutionaryTraceⁱ

Q96CD2

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.Curated

Phylogenomic databases

eggNOGⁱ	KOG0672 Eukaryota COG0452 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00440000038107
HOGENOMⁱ	HOG000187629
HOVERGENⁱ	HBG054722
InParanoidⁱ	Q96CD2
KEGG Orthology (KO) More...KOⁱ	K01598
OMAⁱ	KHFYSPQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0SB2
PhylomeDBⁱ	Q96CD2
TreeFamⁱ	TF315740

Family and domain databases

Gene3Dⁱ	3.40.50.1950, 1 hit
InterProⁱ	View protein in InterPro IPR036551 Flavin_trans-like IPR003382 Flavoprotein
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02441 Flavoprotein, 1 hit
SUPFAMⁱ	SSF52507 SSF52507, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q96CD2-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEPKASCPAA APLMERKFHV LVGVTGSVAA LKLPLLVSKL LDIPGLEVAV 
        60         70         80         90        100
VTTERAKHFY SPQDIPVTLY SDADEWEIWK SRSDPVLHID LRRWADLLLV 
       110        120        130        140        150
APLDANTLGK VASGICDNLL TCVMRAWDRS KPLLFCPAMN TAMWEHPITA 
       160        170        180        190        200
QQVDQLKAFG YVEIPCVAKK LVCGDEGLGA MAEVGTIVDK VKEVLFQHSG 

FQQS

Length:204

Mass (Da):22,395

Last modified:May 18, 2010 - v2

Checksum:ⁱ9E59683480032894

GO

Isoform 2 (identifier: Q96CD2-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-78: MEPKASCPAA...LYSDADEWEI → M

« Hide

        10         20         30         40         50
MWKSRSDPVL HIDLRRWADL LLVAPLDANT LGKVASGICD NLLTCVMRAW 
        60         70         80         90        100
DRSKPLLFCP AMNTAMWEHP ITAQQVDQLK AFGYVEIPCV AKKLVCGDEG 
       110        120 
LGAMAEVGTI VDKVKEVLFQ HSGFQQS

Note: The Met-1 codon is associated with a polymorphism (dbSNP:rs2304899) that replaces the initiation ATG codon by an ATA codon.

Show »

Length:127

Mass (Da):14,069

Checksum:ⁱ562D659DE77C0AF5

GO

Computationally mapped potential isoform sequencesⁱ

There are 6 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

H3BU63	H3BU63_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase, isoform CRA_a	PPCDC hCG_21917	81	Annotation score:
H3BSE3	H3BSE3_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase	PPCDC	129	Annotation score:
H3BQB0	H3BQB0_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase	PPCDC	161	Annotation score:
H3BRQ0	H3BRQ0_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase	PPCDC	172	Annotation score:
H3BPW5	H3BPW5_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase	PPCDC	64	Annotation score:
H3BU34	H3BU34_HUMAN	Phosphopantothenoylcysteine decarbo... Phosphopantothenoylcysteine decarboxylase	PPCDC	62	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	49	A → S in BAB55151 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_068974	78	I → M. Corresponds to variant dbSNP:rs2304899Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_044802	1 – 78	MEPKA…DEWEI → M in isoform 2. 1 PublicationAdd BLAST		78

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF182419 mRNA Translation: AAG14955.1 AY358848 mRNA Translation: AAQ89207.1 AK027491 mRNA Translation: BAB55151.1 AC015720 Genomic DNA No translation available. BC014409 mRNA Translation: AAH14409.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS10275.1 [Q96CD2-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001288030.1, NM_001301101.1 NP_001288031.1, NM_001301102.1 NP_001288032.1, NM_001301103.1 NP_001288033.1, NM_001301104.1 NP_001288034.1, NM_001301105.1 NP_068595.3, NM_021823.4 [Q96CD2-1]
UniGeneⁱ	Hs.458922

Genome annotation databases

Ensemblⁱ	ENST00000342932; ENSP00000343190; ENSG00000138621 [Q96CD2-1]
GeneIDⁱ	60490
KEGGⁱ	hsa:60490
UCSC genome browser More...UCSCⁱ	uc002azo.4 human [Q96CD2-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Protein	Similar proteins		Species	Score	Length	Source
Q96CD2	Uncharacterized protein		PROCO		204	UniRef90_Q96CD2
Phosphopantothenoylcysteine decarboxylase, isoform CRA_a		HUMAN		81
UPI00093B91E0		great roundleaf bat		237
UPI0002BCD89B		ORCOR		221
UPI000945BF4E		Chinese rufous horseshoe bat		204
+3

Protein	Similar proteins		Species	Score	Length	Source
Q96CD2	Uncharacterized protein		PROCO		204	UniRef50_Q96CD2
Phosphopantothenoylcysteine decarboxylase, isoform CRA_a		HUMAN		81
Phosphopantothenoylcysteine decarboxylase (Fragment)		EGRGA		202
Phosphopantothenoylcysteine decarboxylase		TAUER		210
Phosphopantothenoylcysteine decarboxylase		LEPDC		210
+43

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF182419 mRNA Translation: AAG14955.1 AY358848 mRNA Translation: AAQ89207.1 AK027491 mRNA Translation: BAB55151.1 AC015720 Genomic DNA No translation available. BC014409 mRNA Translation: AAH14409.1
CCDSⁱ	CCDS10275.1 [Q96CD2-1]
RefSeqⁱ	NP_001288030.1, NM_001301101.1 NP_001288031.1, NM_001301102.1 NP_001288032.1, NM_001301103.1 NP_001288033.1, NM_001301104.1 NP_001288034.1, NM_001301105.1 NP_068595.3, NM_021823.4 [Q96CD2-1]
UniGeneⁱ	Hs.458922

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1QZU	X-ray	2.91	A/B/C/D	1-204	[»]
ProteinModelPortalⁱ	Q96CD2
SMRⁱ	Q96CD2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	121921, 11 interactors
IntActⁱ	Q96CD2, 16 interactors
MINTⁱ	Q96CD2
STRINGⁱ	9606.ENSP00000343190

Chemistry databases

DrugBankⁱ	DB03738 Pantothenoylaminoethenethiol DB03247 Riboflavin Monophosphate

DrugBankⁱ

DB03738 Pantothenoylaminoethenethiol
DB03247 Riboflavin Monophosphate

PTM databases

iPTMnetⁱ	Q96CD2
PhosphoSitePlusⁱ	Q96CD2

Polymorphism and mutation databases

BioMutaⁱ	PPCDC
DMDMⁱ	296434457

Proteomic databases

EPDⁱ	Q96CD2
MaxQBⁱ	Q96CD2
PaxDbⁱ	Q96CD2
PeptideAtlasⁱ	Q96CD2
PRIDEⁱ	Q96CD2
ProteomicsDBⁱ	76180 76181 [Q96CD2-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	60490
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000342932; ENSP00000343190; ENSG00000138621 [Q96CD2-1]
GeneIDⁱ	60490
KEGGⁱ	hsa:60490
UCSCⁱ	uc002azo.4 human [Q96CD2-1]

Organism-specific databases

CTDⁱ	60490
DisGeNETⁱ	60490
EuPathDBⁱ	HostDB:ENSG00000138621.11
GeneCardsⁱ	PPCDC
H-InvDBⁱ	HIX0202140
HGNCⁱ	HGNC:28107 PPCDC
HPAⁱ	HPA045667
MIMⁱ	609854 gene
neXtProtⁱ	NX_Q96CD2
OpenTargetsⁱ	ENSG00000138621
PharmGKBⁱ	PA142671157
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0672 Eukaryota COG0452 LUCA
GeneTreeⁱ	ENSGT00440000038107
HOGENOMⁱ	HOG000187629
HOVERGENⁱ	HBG054722
InParanoidⁱ	Q96CD2
KOⁱ	K01598
OMAⁱ	KHFYSPQ
OrthoDBⁱ	EOG091G0SB2
PhylomeDBⁱ	Q96CD2
TreeFamⁱ	TF315740

Enzyme and pathway databases

UniPathwayⁱ	UPA00241;UER00354
BioCycⁱ	MetaCyc:HS13735-MONOMER
Reactomeⁱ	R-HSA-196783 Coenzyme A biosynthesis
SABIO-RKⁱ	Q96CD2

Miscellaneous databases

ChiTaRSⁱ	PPCDC human
EvolutionaryTraceⁱ	Q96CD2
GenomeRNAiⁱ	60490
Protein Ontology More...PROⁱ	PR:Q96CD2
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000138621 Expressed in 170 organ(s), highest expression level in blood
CleanExⁱ	HS_PPCDC
ExpressionAtlasⁱ	Q96CD2 baseline and differential
Genevisibleⁱ	Q96CD2 HS

Family and domain databases

Gene3Dⁱ	3.40.50.1950, 1 hit
InterProⁱ	View protein in InterPro IPR036551 Flavin_trans-like IPR003382 Flavoprotein
Pfamⁱ	View protein in Pfam PF02441 Flavoprotein, 1 hit
SUPFAMⁱ	SSF52507 SSF52507, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	COAC_HUMAN
Accessionⁱ	Q96CD2Primary (citable) accession number: Q96CD2 Secondary accession number(s): Q96SX0, Q9HC17
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
	Last sequence update:	May 18, 2010
	Last modified:	September 12, 2018
	This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
SIMILARITY comments
Index of protein domains and families
PATHWAY comments
Index of metabolic and biosynthesis pathways
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 15
Human chromosome 15: entries, gene names and cross-references to MIM
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q96CD2 (COAC_HUMAN)

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Phosphopantothenoylcysteine decarboxylase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: coenzyme A biosynthesis

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

Pathwayⁱ: coenzyme A biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ