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Protein

Protein FAM136A

Gene

FAM136A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM136A
Gene namesi
Name:FAM136A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000035141.7
HGNCiHGNC:25911 FAM136A
MIMi616275 gene
neXtProtiNX_Q96C01

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

DisGeNETi84908
MalaCardsiFAM136A
OpenTargetsiENSG00000035141
PharmGKBiPA162386322

Polymorphism and mutation databases

BioMutaiFAM136A
DMDMi74751785

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002969502 – 138Protein FAM136AAdd BLAST137

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineCombined sources1
Modified residuei124PhosphothreonineBy similarity1
Modified residuei126PhosphothreonineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ96C01
MaxQBiQ96C01
PaxDbiQ96C01
PeptideAtlasiQ96C01
PRIDEiQ96C01
ProteomicsDBi76138

PTM databases

iPTMnetiQ96C01
PhosphoSitePlusiQ96C01

Expressioni

Gene expression databases

BgeeiENSG00000035141
CleanExiHS_FAM136A
ExpressionAtlasiQ96C01 baseline and differential
GenevisibleiQ96C01 HS

Organism-specific databases

HPAiHPA030103
HPA030104

Interactioni

Protein-protein interaction databases

BioGridi124345, 59 interactors
IntActiQ96C01, 11 interactors
MINTiQ96C01
STRINGi9606.ENSP00000037869

Structurei

3D structure databases

ProteinModelPortaliQ96C01
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM136 family.Curated

Phylogenomic databases

eggNOGiKOG3377 Eukaryota
ENOG4111PBH LUCA
GeneTreeiENSGT00390000006707
HOGENOMiHOG000007920
HOVERGENiHBG105585
InParanoidiQ96C01
PhylomeDBiQ96C01
TreeFamiTF315119

Family and domain databases

InterProiView protein in InterPro
IPR008560 DUF842_euk
PANTHERiPTHR21096 PTHR21096, 1 hit
PfamiView protein in Pfam
PF05811 DUF842, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q96C01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAELQQLRVQ EAVESMVKSL ERENIRKMQG LMFRCSASCC EDSQASMKQV
60 70 80 90 100
HQCIERCHVP LAQAQALVTS ELEKFQDRLA RCTMHCNDKA KDSIDAGSKE
110 120 130
LQVKQQLDSC VTKCVDDHMH LIPTMTKKMK EALLSIGK
Length:138
Mass (Da):15,641
Last modified:December 1, 2001 - v1
Checksum:i72D3CA33B937F8B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti13V → M in BAB55208 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027574 mRNA Translation: BAB55208.1
AC022201 Genomic DNA Translation: AAX93110.1
BC014975 mRNA Translation: AAH14975.1
CCDSiCCDS1904.1
RefSeqiNP_116211.2, NM_032822.2
UniGeneiHs.516077

Genome annotation databases

EnsembliENST00000037869; ENSP00000037869; ENSG00000035141
GeneIDi84908
KEGGihsa:84908
UCSCiuc002sgq.5 human

Similar proteinsi

Entry informationi

Entry nameiF136A_HUMAN
AccessioniPrimary (citable) accession number: Q96C01
Secondary accession number(s): Q96SS3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

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