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UniProtKB - Q96BZ8 (LENG1_HUMAN)

Entry version 129 (23 Feb 2022)
Sequence version 2 (23 Feb 2022)
Previous versions | rss
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Protein

Leukocyte receptor cluster member 1

Gene

LENG1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Belongs to the leukocyte receptor cluster (LRC) present on 19q13.4.

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96BZ8

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q96BZ8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leukocyte receptor cluster member 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LENG1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:15502, LENG1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96BZ8

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000105617

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134904804

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96BZ8, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		LENG1

Domain mapping of disease mutations (DMDM)

More...DMDMi		74731296

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002546271 – 264Leukocyte receptor cluster member 1Add BLAST264

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei59PhosphoserineCombined sources1
Modified residuei245PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96BZ8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96BZ8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96BZ8

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96BZ8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96BZ8

PeptideAtlas

More...PeptideAtlasi		Q96BZ8

PRoteomics IDEntifications database

More...PRIDEi		Q96BZ8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		76133

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q96BZ8, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96BZ8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96BZ8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000105617, Expressed in quadriceps femoris and 194 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96BZ8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000105617, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q96BZ8
With#Exp.IntAct
ABI2 - isoform 2 [Q9NYB9-2]3EBI-726510,EBI-11096309
ASB12 - isoform 2 [Q8WXK4-2]3EBI-726510,EBI-18394052
BANP [Q8N9N5]4EBI-726510,EBI-744695
BEGAIN [Q9BUH8]3EBI-726510,EBI-742722
C14orf119 [Q9NWQ9]3EBI-726510,EBI-725606
CALCOCO2 [Q13137]3EBI-726510,EBI-739580
CARD10 [Q9BWT7]3EBI-726510,EBI-3866279
CARD9 [Q9H257]3EBI-726510,EBI-751319
CARD9 - isoform 2 [Q9H257-2]3EBI-726510,EBI-11530605
CBY2 [Q8NA61]3EBI-726510,EBI-741724
CCDC102B [Q68D86]3EBI-726510,EBI-10171570
CCDC136 - isoform 2 [Q96JN2-2]3EBI-726510,EBI-10171416
CCDC57 [Q2TAC2]3EBI-726510,EBI-2808286
CCDC57 - isoform 2 [Q2TAC2-2]3EBI-726510,EBI-10961624
CCHCR1 - isoform 3 [Q8TD31-3]3EBI-726510,EBI-10175300
CDR2 [Q01850]6EBI-726510,EBI-1181367
CDR2L [Q86X02]3EBI-726510,EBI-11063830
CEP57L1 - isoform 2 [Q8IYX8-2]3EBI-726510,EBI-10181988
CEP70 [Q8NHQ1]7EBI-726510,EBI-739624
DDIT4L [Q96D03]3EBI-726510,EBI-742054
DES [P17661]3EBI-726510,EBI-1055572
DISC1 - isoform 2 [Q9NRI5-2]3EBI-726510,EBI-11988027
EVI5 [O60447]3EBI-726510,EBI-852291
FSD2 [A1L4K1]6EBI-726510,EBI-5661036
GFAP [P14136]3EBI-726510,EBI-744302
GOLGA2 [Q08379]8EBI-726510,EBI-618309
GOLGA6L9 [A6NEM1]3EBI-726510,EBI-5916454
HOOK2 - isoform 2 [Q96ED9-2]3EBI-726510,EBI-10961706
IKZF3 [Q9UKT9]3EBI-726510,EBI-747204
ISY1 - isoform 2 [Q9ULR0-1]3EBI-726510,EBI-18398632
KANK2 [Q63ZY3]3EBI-726510,EBI-2556193
KASH5 [Q8N6L0]3EBI-726510,EBI-749265
KIFC3 [Q9BVG8]3EBI-726510,EBI-2125614
KIFC3 - isoform 4 [Q9BVG8-5]3EBI-726510,EBI-14069005
KRT19 [P08727]3EBI-726510,EBI-742756
KRT31 [Q15323]6EBI-726510,EBI-948001
KRT35 [Q92764]3EBI-726510,EBI-1058674
KRT40 [Q6A162]6EBI-726510,EBI-10171697
KRTAP10-8 [P60410]3EBI-726510,EBI-10171774
LDOC1 [O95751]8EBI-726510,EBI-740738
LRP2BP [Q9P2M1]3EBI-726510,EBI-18273118
LZTS1 [Q9Y250]3EBI-726510,EBI-1216080
MAB21L3 [Q8N8X9]3EBI-726510,EBI-10268010
MAD1L1 [Q9Y6D9]3EBI-726510,EBI-742610
MEIS3 - isoform 3 [Q99687-3]3EBI-726510,EBI-18582591
MID2 - isoform 2 [Q9UJV3-2]6EBI-726510,EBI-10172526
MIPOL1 [Q8TD10]3EBI-726510,EBI-2548751
MRPL28 [Q13084]3EBI-726510,EBI-723426
MTUS2 [Q5JR59]3EBI-726510,EBI-742948
MTUS2 - isoform 2 [Q5JR59-3]3EBI-726510,EBI-11522433
NAB2 [Q15742]6EBI-726510,EBI-8641936
NECAB2 - isoform 2 [Q7Z6G3-2]3EBI-726510,EBI-10172876
NTAQ1 [Q96HA8]3EBI-726510,EBI-741158
NUTF2 [P61970]3EBI-726510,EBI-591778
OIP5 [O43482]3EBI-726510,EBI-536879
PAK5 [Q9P286]3EBI-726510,EBI-741896
PDE4DIP [Q5VU43]3EBI-726510,EBI-1105124
PRKAR1B [P31321]3EBI-726510,EBI-2805516
PRPH [P41219]3EBI-726510,EBI-752074
PSMB1 [P20618]3EBI-726510,EBI-372273
RABEP1 [Q15276]3EBI-726510,EBI-447043
REL - isoform 2 [Q04864-2]4EBI-726510,EBI-10829018
ROPN1 [Q9HAT0]8EBI-726510,EBI-1378139
SCYL1 - isoform 4 [Q96KG9-4]3EBI-726510,EBI-12023020
SPATA2 [Q9UM82]3EBI-726510,EBI-744066
STX11 [O75558]3EBI-726510,EBI-714135
TCF4 [P15884]3EBI-726510,EBI-533224
TEPSIN [Q96N21]3EBI-726510,EBI-11139477
TEX12 [Q9BXU0]3EBI-726510,EBI-12090309
TFIP11 [Q9UBB9]3EBI-726510,EBI-1105213
TMEM239 [Q8WW34]3EBI-726510,EBI-9675724
TRAF2 [Q12933]3EBI-726510,EBI-355744
TRIB3 [Q96RU7]3EBI-726510,EBI-492476
TRIM23 [P36406]3EBI-726510,EBI-740098
TRIM27 [P14373]3EBI-726510,EBI-719493
TRIM54 [Q9BYV2]6EBI-726510,EBI-2130429
TSC1 [Q86WV8]3EBI-726510,EBI-12806590
UBL5 [Q9BZL1]3EBI-726510,EBI-607755
UBXN11 - isoform 6 [Q5T124-6]3EBI-726510,EBI-11524408
USHBP1 [Q8N6Y0]3EBI-726510,EBI-739895
ZMYND12 [Q9H0C1]3EBI-726510,EBI-12030590
ZRANB1 [Q9UGI0]3EBI-726510,EBI-527853

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122582, 110 interactors

Protein interaction database and analysis system

More...IntActi		Q96BZ8, 93 interactors

Molecular INTeraction database

More...MINTi		Q96BZ8

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000222224

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96BZ8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96BZ8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni49 – 76DisorderedSequence analysisAdd BLAST28
Regioni118 – 264DisorderedSequence analysisAdd BLAST147

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili16 – 46Sequence analysisAdd BLAST31
Coiled coili89 – 115Sequence analysisAdd BLAST27
Coiled coili196 – 222Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi133 – 147Pro residuesSequence analysisAdd BLAST15
Compositional biasi148 – 214Basic and acidic residuesSequence analysisAdd BLAST67
Compositional biasi227 – 244Basic and acidic residuesSequence analysisAdd BLAST18

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RZ97, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_058751_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96BZ8

Database of Orthologous Groups

More...OrthoDBi		1518973at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96BZ8

TreeFam database of animal gene trees

More...TreeFami		TF317830

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019339, CIR_N_dom
IPR039875, LENG1-like

The PANTHER Classification System

More...PANTHERi		PTHR22093, PTHR22093, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10197, Cir_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01083, Cir_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96BZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNILPKKSWH VRNKDNVARV RRDEAQAREE EKERERRVLL AQQEARTEFL 
        60         70         80         90        100
RKKARHQNSL PELEAAEAGA PGSGPVDLFR ELLEEGKGVI RGNKEYKEEK 
       110        120        130        140        150
RQEKERQEKA LGILTYLGQS AAEAQTQPPW YQLPPGRGGP PPGPAPDEKI 
       160        170        180        190        200
KSRLDPLREM QKHLGKKRQH GGDEGSRSRK EKEGSEKQRP KEPPSLDQLR 
       210        220        230        240        250
AERLRREAAE RSRAEALLAR VQGRALQEGQ PEEDETDDRR RRYNSQFNPQ 
       260 
LARRPRQQDP HLTH
Length:264
Mass (Da):30,528
Last modified:February 23, 2022 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i324AD76EA1165C44
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG01393 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05109097K → E. Corresponds to variant dbSNP:rs35089861Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC245052 Genomic DNA No translation available.
BC014986 mRNA Translation: AAH14986.1
AF211966 mRNA Translation: AAG01393.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12881.1

NCBI Reference Sequences

More...RefSeqi		NP_077292.2, NM_024316.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000222224; ENSP00000222224; ENSG00000105617
ENST00000610998; ENSP00000481386; ENSG00000276959
ENST00000613622; ENSP00000478485; ENSG00000278516
ENST00000614037; ENSP00000483164; ENSG00000276774
ENST00000616103; ENSP00000481252; ENSG00000277808
ENST00000616816; ENSP00000480516; ENSG00000277457
ENST00000617592; ENSP00000481079; ENSG00000278426
ENST00000619669; ENSP00000477607; ENSG00000276628
ENST00000621285; ENSP00000479538; ENSG00000278257
ENST00000621927; ENSP00000481948; ENSG00000275935

Database of genes from NCBI RefSeq genomes

More...GeneIDi		79165

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:79165

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000222224.4; ENSP00000222224.3; NM_024316.3; NP_077292.2

UCSC genome browser

More...UCSCi		uc002qdm.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC245052 Genomic DNA No translation available.
BC014986 mRNA Translation: AAH14986.1
AF211966 mRNA Translation: AAG01393.1 Different initiation.
CCDSiCCDS12881.1
RefSeqiNP_077292.2, NM_024316.2

3D structure databases

SMRiQ96BZ8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi122582, 110 interactors
IntActiQ96BZ8, 93 interactors
MINTiQ96BZ8
STRINGi9606.ENSP00000222224

PTM databases

GlyGeniQ96BZ8, 1 site, 1 O-linked glycan (1 site)
iPTMnetiQ96BZ8
PhosphoSitePlusiQ96BZ8

Genetic variation databases

BioMutaiLENG1
DMDMi74731296

Proteomic databases

EPDiQ96BZ8
jPOSTiQ96BZ8
MassIVEiQ96BZ8
MaxQBiQ96BZ8
PaxDbiQ96BZ8
PeptideAtlasiQ96BZ8
PRIDEiQ96BZ8
ProteomicsDBi76133

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		46337, 203 antibodies from 18 providers

The DNASU plasmid repository

More...DNASUi		79165

Genome annotation databases

EnsembliENST00000222224; ENSP00000222224; ENSG00000105617
ENST00000610998; ENSP00000481386; ENSG00000276959
ENST00000613622; ENSP00000478485; ENSG00000278516
ENST00000614037; ENSP00000483164; ENSG00000276774
ENST00000616103; ENSP00000481252; ENSG00000277808
ENST00000616816; ENSP00000480516; ENSG00000277457
ENST00000617592; ENSP00000481079; ENSG00000278426
ENST00000619669; ENSP00000477607; ENSG00000276628
ENST00000621285; ENSP00000479538; ENSG00000278257
ENST00000621927; ENSP00000481948; ENSG00000275935
GeneIDi79165
KEGGihsa:79165
MANE-SelectiENST00000222224.4; ENSP00000222224.3; NM_024316.3; NP_077292.2
UCSCiuc002qdm.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79165

GeneCards: human genes, protein and diseases

More...GeneCardsi		LENG1
HGNCiHGNC:15502, LENG1
HPAiENSG00000105617, Low tissue specificity
neXtProtiNX_Q96BZ8
PharmGKBiPA134904804
VEuPathDBiHostDB:ENSG00000105617

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502RZ97, Eukaryota
HOGENOMiCLU_058751_2_0_1
InParanoidiQ96BZ8
OrthoDBi1518973at2759
PhylomeDBiQ96BZ8
TreeFamiTF317830

Enzyme and pathway databases

PathwayCommonsiQ96BZ8
SignaLinkiQ96BZ8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		79165, 184 hits in 1041 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		LENG1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		79165
PharosiQ96BZ8, Tdark

Protein Ontology

More...PROi		PR:Q96BZ8
RNActiQ96BZ8, protein

Gene expression databases

BgeeiENSG00000105617, Expressed in quadriceps femoris and 194 other tissues
GenevisibleiQ96BZ8, HS

Family and domain databases

InterProiView protein in InterPro
IPR019339, CIR_N_dom
IPR039875, LENG1-like
PANTHERiPTHR22093, PTHR22093, 1 hit
PfamiView protein in Pfam
PF10197, Cir_N, 1 hit
SMARTiView protein in SMART
SM01083, Cir_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLENG1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96BZ8
Secondary accession number(s): Q9HCU7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: February 23, 2022
Last modified: February 23, 2022
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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