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Entry version 139 (08 May 2019)
Sequence version 5 (05 Oct 2010)
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Protein

Autophagy-related protein 2 homolog B

Gene

ATG2B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • autophagosome assembly Source: GO_Central
  • autophagy of mitochondrion Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAutophagy

Protein family/group databases

Transport Classification Database

More...
TCDBi
9.A.15.2.1 the autophagy-related phagophore-formation transporter (apt) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Autophagy-related protein 2 homolog B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATG2B
Synonyms:C14orf103
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20187 ATG2B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616226 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96BY7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Lipid droplet, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55102

Open Targets

More...
OpenTargetsi
ENSG00000066739

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162377102

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ATG2B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
308153682

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000899091 – 2078Autophagy-related protein 2 homolog BAdd BLAST2078

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei255PhosphoserineCombined sources1
Modified residuei379PhosphoserineBy similarity1
Modified residuei497PhosphoserineCombined sources1
Modified residuei840PhosphoserineCombined sources1
Modified residuei886PhosphoserineCombined sources1
Modified residuei899PhosphoserineCombined sources1
Modified residuei1008PhosphoserineBy similarity1
Modified residuei1012PhosphotyrosineBy similarity1
Modified residuei1016PhosphoserineBy similarity1
Modified residuei1018PhosphoserineCombined sources1
Modified residuei1022PhosphothreonineBy similarity1
Modified residuei1526PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96BY7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96BY7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96BY7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96BY7

PeptideAtlas

More...
PeptideAtlasi
Q96BY7

PRoteomics IDEntifications database

More...
PRIDEi
Q96BY7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76129

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96BY7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96BY7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000066739 Expressed in 213 organ(s), highest expression level in middle temporal gyrus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96BY7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000880
HPA001427
HPA019665

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120412, 35 interactors

Protein interaction database and analysis system

More...
IntActi
Q96BY7, 14 interactors

Molecular INTeraction database

More...
MINTi
Q96BY7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000353010

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATG2 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2993 Eukaryota
ENOG410XRAR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00620000087966

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000034149

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96BY7

KEGG Orthology (KO)

More...
KOi
K17906

Identification of Orthologs from Complete Genome Data

More...
OMAi
HYVCLHS

Database of Orthologous Groups

More...
OrthoDBi
196897at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96BY7

TreeFam database of animal gene trees

More...
TreeFami
TF313482

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026849 ATG2
IPR015412 Autophagy-rel_C
IPR026854 VPS13_N

The PANTHER Classification System

More...
PANTHERi
PTHR13190 PTHR13190, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09333 ATG_C, 1 hit
PF12624 Chorein_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96BY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPWPFSESIK KRACRYLLQR YLGHFLQEKL SLEQLSLDLY QGTGSLAQVP
60 70 80 90 100
LDKWCLNEIL ESADAPLEVT EGFIQSISLS VPWGSLLQDN CALEVRGLEM
110 120 130 140 150
VFRPRPRPAT GSEPMYWSSF MTSSMQLAKE CLSQKLTDEQ GEGSQPFEGL
160 170 180 190 200
EKFAETIETV LRRVKVTFID TVLRIEHVPE NSKTGTALEI RIERTVYCDE
210 220 230 240 250
TADESSGINV HQPTAFAHKL LQLSGVSLFW DEFSASAKSS PVCSTAPVET
260 270 280 290 300
EPKLSPSWNP KIIYEPHPQL TRNLPEIAPS DPVQIGRLIG RLELSLTLKQ
310 320 330 340 350
NEVLPGAKLD VDGQIDSIHL LLSPRQVHLL LDMLAAIAGP ENSSKIGLAN
360 370 380 390 400
KDRKNRPMQQ EDEYRIQMEL NRYYLRKDSL SVGVSSEQSF YETETARTPS
410 420 430 440 450
SREEEVFFSM ADMDMSHSLS SLPPLGDPPN MDLELSLTST YTNTPAGSPL
460 470 480 490 500
SATVLQPTWG EFLDHHKEQP VRGSTFPSNL VHPTPLQKTS LPSRSVSVDE
510 520 530 540 550
SRPELIFRLA VGTFSISVLH IDPLSPPETS QNLNPLTPMA VAFFTCIEKI
560 570 580 590 600
DPARFSTEDF KSFRAVFAEA CSHDHLRFIG TGIKVSYEQR QRSASRYFST
610 620 630 640 650
DMSIGQMEFL ECLFPTDFHS VPPHYTELLT FHSKEETGSH SPVCLQLHYK
660 670 680 690 700
HSENRGPQGN QARLSSVPHK AELQIKLNPV CCELDISIVD RLNSLLQPQK
710 720 730 740 750
LATVEMMASH MYTSYNKHIS LHKAFTEVFL DDSHSPANCR ISVQVATPAL
760 770 780 790 800
NLSVRFPIPD LRSDQERGPW FKKSLQKEIL YLAFTDLEFK TEFIGGSTPE
810 820 830 840 850
QIKLELTFRE LIGSFQEEKG DPSIKFFHVS SGVDGDTTSS DDFDWPRIVL
860 870 880 890 900
KINPPAMHSI LERIAAEEEE ENDGHYQEEE EGGAHSLKDV CDLRRPAPSP
910 920 930 940 950
FSSRRVMFEN EQMVMPGDPV EMTEFQDKAI SNSHYVLELT LPNIYVTLPN
960 970 980 990 1000
KSFYEKLYNR IFNDLLLWEP TAPSPVETFE NISYGIGLSV ASQLINTFNK
1010 1020 1030 1040 1050
DSFSAFKSAV HYDEESGSEE ETLQYFSTVD PNYRSRRKKK LDSQNKNSQS
1060 1070 1080 1090 1100
FLSVLLNINH GLIAVFTDVK QDNGDLLENK HGEFWLEFNS GSLFCVTKYE
1110 1120 1130 1140 1150
GFDDKHYICL HSSSFSLYHK GIVNGVILPT ETRLPSSTRP HWLEPTIYSS
1160 1170 1180 1190 1200
EEDGLSKTSS DGVGGDSLNM LSVAVKILSD KSESNTKEFL IAVGLKGATL
1210 1220 1230 1240 1250
QHRMLPSGLS WHEQILYFLN IADEPVLGYN PPTSFTTFHV HLWSCALDYR
1260 1270 1280 1290 1300
PLYLPIRSLL TVETFSVSSS VALDKSSSTL RIILDEAALH LSDKCNTVTI
1310 1320 1330 1340 1350
NLSRDYVRVM DMGLLELTIT AVKSDSDGEQ TEPRFELHCS SDVVHIRTCS
1360 1370 1380 1390 1400
DSCAALMNLI QYIASYGDLQ TPNKADMKPG AFQRRSKVDS SGRSSSRGPV
1410 1420 1430 1440 1450
LPEADQQMLR DLMSDAMEEI DMQQGTSSVK PQANGVLDEK SQIQEPCCSD
1460 1470 1480 1490 1500
LFLFPDESGN VSQESGPTYA SFSHHFISDA MTGVPTENDD FCILFAPKAA
1510 1520 1530 1540 1550
MQEKEEEPVI KIMVDDAIVI RDNYFSLPVN KTDTSKAPLH FPIPVIRYVV
1560 1570 1580 1590 1600
KEVSLVWHLY GGKDFGIVPP TSPAKSYISP HSSPSHTPTR HGRNTVCGGK
1610 1620 1630 1640 1650
GRNHDFLMEI QLSKVKFQHE VYPPCKPDCD SSLSEHPVSR QVFIVQDLEI
1660 1670 1680 1690 1700
RDRLATSQMN KFLYLYCSKE MPRKAHSNML TVKALHVCPE SGRSPQECCL
1710 1720 1730 1740 1750
RVSLMPLRLN IDQDALFFLK DFFTSLSAEV ELQMTPDPEV KKSPGADVTC
1760 1770 1780 1790 1800
SLPRHLSTSK EPNLVISFSG PKQPSQNDSA NSVEVVNGME EKNFSAEEAS
1810 1820 1830 1840 1850
FRDQPVFFRE FRFTSEVPIR LDYHGKHVSM DQGTLAGILI GLAQLNCSEL
1860 1870 1880 1890 1900
KLKRLSYRHG LLGVDKLFSY AITEWLNDIK KNQLPGILGG VGPMHSLVQL
1910 1920 1930 1940 1950
VQGLKDLVWL PIEQYRKDGR IVRGFQRGAA SFGTSTAMAA LELTNRMVQT
1960 1970 1980 1990 2000
IQAAAETAYD MVSPGTLSIE PKKTKRFPHH RLAHQPVDLR EGVAKAYSVV
2010 2020 2030 2040 2050
KEGITDTAQT IYETAAREHE SRGVTGAVGE VLRQIPPAVV KPLIVATEAT
2060 2070
SNVLGGMRNQ IRPDVRQDES QKWRHGDD
Length:2,078
Mass (Da):232,763
Last modified:October 5, 2010 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA573F5C64D96C36
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA91504 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB70872 differs from that shown. Reason: Erroneous termination at position 800. Translated as Glu.Curated
The sequence BAC87363 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti765Q → R in BAB70872 (PubMed:14702039).Curated1
Sequence conflicti1905K → E in BAA91504 (PubMed:14702039).Curated1
Sequence conflicti1932F → S in BAC87363 (PubMed:14702039).Curated1
Sequence conflicti2062R → G in BAA91504 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0459561124N → D1 PublicationCorresponds to variant dbSNP:rs9323945Ensembl.1
Natural variantiVAR_0215231383Q → E2 PublicationsCorresponds to variant dbSNP:rs3759601Ensembl.1
Natural variantiVAR_0230961567I → T2 PublicationsCorresponds to variant dbSNP:rs2289622Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL355102 Genomic DNA No translation available.
AL359240 Genomic DNA No translation available.
AK001104 mRNA Translation: BAA91504.1 Different initiation.
AK055200 mRNA Translation: BAB70872.1 Sequence problems.
AK128275 mRNA Translation: BAC87363.1 Different initiation.
BC015016 mRNA Translation: AAH15016.3

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9944.2

NCBI Reference Sequences

More...
RefSeqi
NP_060506.5, NM_018036.6

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359933; ENSP00000353010; ENSG00000066739

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55102

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55102

UCSC genome browser

More...
UCSCi
uc001yfi.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355102 Genomic DNA No translation available.
AL359240 Genomic DNA No translation available.
AK001104 mRNA Translation: BAA91504.1 Different initiation.
AK055200 mRNA Translation: BAB70872.1 Sequence problems.
AK128275 mRNA Translation: BAC87363.1 Different initiation.
BC015016 mRNA Translation: AAH15016.3
CCDSiCCDS9944.2
RefSeqiNP_060506.5, NM_018036.6

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi120412, 35 interactors
IntActiQ96BY7, 14 interactors
MINTiQ96BY7
STRINGi9606.ENSP00000353010

Protein family/group databases

TCDBi9.A.15.2.1 the autophagy-related phagophore-formation transporter (apt) family

PTM databases

iPTMnetiQ96BY7
PhosphoSitePlusiQ96BY7

Polymorphism and mutation databases

BioMutaiATG2B
DMDMi308153682

Proteomic databases

EPDiQ96BY7
jPOSTiQ96BY7
MaxQBiQ96BY7
PaxDbiQ96BY7
PeptideAtlasiQ96BY7
PRIDEiQ96BY7
ProteomicsDBi76129

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55102
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359933; ENSP00000353010; ENSG00000066739
GeneIDi55102
KEGGihsa:55102
UCSCiuc001yfi.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55102
DisGeNETi55102

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ATG2B
HGNCiHGNC:20187 ATG2B
HPAiHPA000880
HPA001427
HPA019665
MIMi616226 gene
neXtProtiNX_Q96BY7
OpenTargetsiENSG00000066739
PharmGKBiPA162377102

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2993 Eukaryota
ENOG410XRAR LUCA
GeneTreeiENSGT00620000087966
HOGENOMiHOG000034149
InParanoidiQ96BY7
KOiK17906
OMAiHYVCLHS
OrthoDBi196897at2759
PhylomeDBiQ96BY7
TreeFamiTF313482

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ATG2B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
55102

Protein Ontology

More...
PROi
PR:Q96BY7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000066739 Expressed in 213 organ(s), highest expression level in middle temporal gyrus
GenevisibleiQ96BY7 HS

Family and domain databases

InterProiView protein in InterPro
IPR026849 ATG2
IPR015412 Autophagy-rel_C
IPR026854 VPS13_N
PANTHERiPTHR13190 PTHR13190, 1 hit
PfamiView protein in Pfam
PF09333 ATG_C, 1 hit
PF12624 Chorein_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATG2B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96BY7
Secondary accession number(s): Q6ZRE7, Q96DQ3, Q9NW80
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: October 5, 2010
Last modified: May 8, 2019
This is version 139 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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