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Entry version 121 (11 Dec 2019)
Sequence version 2 (19 Mar 2014)
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Protein

Phosphatidate cytidylyltransferase, mitochondrial

Gene

TAMM41

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: CDP-diacylglycerol biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.By similarity
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glycerol-3-phosphate acyltransferase 1, mitochondrial, Glycerol-3-phosphate acyltransferase 2, mitochondrial (GPAT2), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM), Glycerol-3-phosphate acyltransferase 1, mitochondrial (DKFZp451B1115), Glycerol-3-phosphate acyltransferase 4 (GPAT4), Glycerol-3-phosphate acyltransferase 3 (GPAT3)
  2. 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5), 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3), 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (AGPAT1), 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2), 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (AGPAT4), Lysocardiolipin acyltransferase 1 (LCLAT1)
  3. Phosphatidate cytidylyltransferase 1 (CDS1), Phosphatidate cytidylyltransferase 2 (CDS2), Phosphatidate cytidylyltransferase, mitochondrial (TAMM41), Phosphatidate cytidylyltransferase (CDS1), Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase, Phosphatidate cytidylyltransferase
This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism
LigandMagnesium

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00557;UER00614

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase, mitochondrial (EC:2.7.7.41By similarity)
Alternative name(s):
CDP-diacylglycerol synthase
Short name:
CDP-DAG synthase
Mitochondrial translocator assembly and maintenance protein 41 homolog
Short name:
TAM41
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAMM41
Synonyms:C3orf31
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000144559.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25187 TAMM41

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614948 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96BW9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000144559

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672392

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96BW9 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TAMM41

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74731287

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 24MitochondrionSequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024835425 – 452Phosphatidate cytidylyltransferase, mitochondrialAdd BLAST428

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96BW9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96BW9

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q96BW9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96BW9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96BW9

PeptideAtlas

More...
PeptideAtlasi
Q96BW9

PRoteomics IDEntifications database

More...
PRIDEi
Q96BW9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
4336
76124 [Q96BW9-1]
8254

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96BW9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96BW9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q96BW9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000144559 Expressed in 133 organ(s), highest expression level in oocyte

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96BW9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96BW9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA036834
HPA044861

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
P067443EBI-13943422,EBI-2558394

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126303, 25 interactors

Protein interaction database and analysis system

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IntActi
Q96BW9, 21 interactors

STRING: functional protein association networks

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STRINGi
9606.ENSP00000398596

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96BW9 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q96BW9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TAM41 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2986 Eukaryota
ENOG410ZNKE LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000616

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000205225

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96BW9

KEGG Orthology (KO)

More...
KOi
K17807

Identification of Orthologs from Complete Genome Data

More...
OMAi
NRIMDPP

Database of Orthologous Groups

More...
OrthoDBi
1145430at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96BW9

TreeFam database of animal gene trees

More...
TreeFami
TF314503

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015222 Tam41

The PANTHER Classification System

More...
PANTHERi
PTHR13619 PTHR13619, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09139 Tam41_Mmp37, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF028840 Mmp37, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96BW9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALQTLQSSW VTFRKILSHF PEELSLAFVY GSGVYRQAGP SSDQKNAMLD
60 70 80 90 100
FVFTVDDPVA WHSKNLKKNW SHYSFLKVLG PKIITSIQNN YGAGVYYNSL
110 120 130 140 150
IMCNGRLIKY GVISTNVLIE DLLNWNNLYI AGRLQKPVKI ISVNEDVTLR
160 170 180 190 200
SALDRNLKSA VTAAFLMLPE SFSEEDLFIE IAGLSYSGDF RMVVGEDKTK
210 220 230 240 250
VLNIVKPNIA HFRELYGSIL QENPQVVYKS QQGWLEIDKS PEGQFTQLMT
260 270 280 290 300
LPKTLQQQIN HIMDPPGKNR DVEETLFQVA HDPDCGDVVR LGLSAIVRPS
310 320 330 340 350
SIRQSTKGIF TAGKSFGNPC VTYLLTEWLP HSWLQCKALY LLGACEMLSF
360 370 380 390 400
DGHKLGYCSK VQTGITAAEP GGRTMSDHWQ CCWKLYCPSE FSETLPVCRV
410 420 430 440 450
FPSYCFIYQS YRCIGLQKQQ HLCSPSSSPS LRQLLPSVLV GYFCCYCHFS

KW
Length:452
Mass (Da):51,067
Last modified:March 19, 2014 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD711A42567390653
GO
Isoform 2 (identifier: Q96BW9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     294-316: SAIVRPSSIRQSTKGIFTAGKSF → KKSVIYSSLKLHKMWKGWLRKTS
     317-452: Missing.

Show »
Length:316
Mass (Da):35,907
Checksum:i06B837C098BB584E
GO
Isoform 3 (identifier: Q96BW9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     314-337: KSFGNPCVTYLLTEWLPHSWLQCK → LKKSVIYSSLKLHKMWKGWLRKTS
     338-452: Missing.

Show »
Length:337
Mass (Da):38,079
Checksum:iE5AF0F9A98E2604A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V0F3G3V0F3_HUMAN
Chromosome 3 open reading frame 31,...
TAMM41 C3orf31, hCG_28045
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B4E101B4E101_HUMAN
Phosphatidate cytidylyltransferase,...
TAMM41
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1A2H7C1A2_HUMAN
Phosphatidate cytidylyltransferase,...
TAMM41
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JQ92A0A0G2JQ92_HUMAN
Phosphatidate cytidylyltransferase,...
TAMM41
236Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027276116N → S. Corresponds to variant dbSNP:rs7641243Ensembl.1
Natural variantiVAR_053649179I → V. Corresponds to variant dbSNP:rs11551661Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_053905294 – 316SAIVR…AGKSF → KKSVIYSSLKLHKMWKGWLR KTS in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_055724314 – 337KSFGN…WLQCK → LKKSVIYSSLKLHKMWKGWL RKTS in isoform 3. CuratedAdd BLAST24
Alternative sequenceiVSP_053906317 – 452Missing in isoform 2. 1 PublicationAdd BLAST136
Alternative sequenceiVSP_055725338 – 452Missing in isoform 3. CuratedAdd BLAST115

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK295839 mRNA Translation: BAG58649.1
AC090939 Genomic DNA No translation available.
AC090958 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64113.1
BC015088 mRNA Translation: AAH15088.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2607.1 [Q96BW9-2]
CCDS68345.1 [Q96BW9-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001271330.1, NM_001284401.1 [Q96BW9-3]
NP_001308223.1, NM_001321294.1
NP_001308224.1, NM_001321295.1
NP_620162.1, NM_138807.3 [Q96BW9-2]
XP_005264930.1, XM_005264873.3 [Q96BW9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000273037; ENSP00000273037; ENSG00000144559 [Q96BW9-2]
ENST00000444133; ENSP00000388598; ENSG00000144559 [Q96BW9-1]
ENST00000455809; ENSP00000398596; ENSG00000144559 [Q96BW9-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
132001

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:132001

UCSC genome browser

More...
UCSCi
uc003bwh.4 human [Q96BW9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295839 mRNA Translation: BAG58649.1
AC090939 Genomic DNA No translation available.
AC090958 Genomic DNA No translation available.
CH471055 Genomic DNA Translation: EAW64113.1
BC015088 mRNA Translation: AAH15088.1
CCDSiCCDS2607.1 [Q96BW9-2]
CCDS68345.1 [Q96BW9-3]
RefSeqiNP_001271330.1, NM_001284401.1 [Q96BW9-3]
NP_001308223.1, NM_001321294.1
NP_001308224.1, NM_001321295.1
NP_620162.1, NM_138807.3 [Q96BW9-2]
XP_005264930.1, XM_005264873.3 [Q96BW9-1]

3D structure databases

SMRiQ96BW9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi126303, 25 interactors
IntActiQ96BW9, 21 interactors
STRINGi9606.ENSP00000398596

PTM databases

iPTMnetiQ96BW9
PhosphoSitePlusiQ96BW9
SwissPalmiQ96BW9

Polymorphism and mutation databases

BioMutaiTAMM41
DMDMi74731287

Proteomic databases

EPDiQ96BW9
jPOSTiQ96BW9
MassIVEiQ96BW9
MaxQBiQ96BW9
PaxDbiQ96BW9
PeptideAtlasiQ96BW9
PRIDEiQ96BW9
ProteomicsDBi4336
76124 [Q96BW9-1]
8254

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
132001

Genome annotation databases

EnsembliENST00000273037; ENSP00000273037; ENSG00000144559 [Q96BW9-2]
ENST00000444133; ENSP00000388598; ENSG00000144559 [Q96BW9-1]
ENST00000455809; ENSP00000398596; ENSG00000144559 [Q96BW9-3]
GeneIDi132001
KEGGihsa:132001
UCSCiuc003bwh.4 human [Q96BW9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
132001
EuPathDBiHostDB:ENSG00000144559.10

GeneCards: human genes, protein and diseases

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GeneCardsi
TAMM41
HGNCiHGNC:25187 TAMM41
HPAiHPA036834
HPA044861
MIMi614948 gene
neXtProtiNX_Q96BW9
OpenTargetsiENSG00000144559
PharmGKBiPA142672392

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG2986 Eukaryota
ENOG410ZNKE LUCA
GeneTreeiENSGT00390000000616
HOGENOMiHOG000205225
InParanoidiQ96BW9
KOiK17807
OMAiNRIMDPP
OrthoDBi1145430at2759
PhylomeDBiQ96BW9
TreeFamiTF314503

Enzyme and pathway databases

UniPathwayiUPA00557;UER00614

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TAMM41 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
132001
PharosiQ96BW9 Tbio

Protein Ontology

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PROi
PR:Q96BW9
RNActiQ96BW9 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000144559 Expressed in 133 organ(s), highest expression level in oocyte
ExpressionAtlasiQ96BW9 baseline and differential
GenevisibleiQ96BW9 HS

Family and domain databases

InterProiView protein in InterPro
IPR015222 Tam41
PANTHERiPTHR13619 PTHR13619, 1 hit
PfamiView protein in Pfam
PF09139 Tam41_Mmp37, 1 hit
PIRSFiPIRSF028840 Mmp37, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAM41_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96BW9
Secondary accession number(s): B4DIY7, C9J2U4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: March 19, 2014
Last modified: December 11, 2019
This is version 121 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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