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Protein

Leukocyte receptor cluster member 9

Gene

LENG9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

It is uncertain whether Met-1 or Met-23 is the initiator.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri40 – 67C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Leukocyte receptor cluster member 9
Gene namesi
Name:LENG9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:16306 LENG9
neXtProtiNX_Q96B70

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134975056

Polymorphism and mutation databases

BioMutaiLENG9
DMDMi296434565

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002636881 – 501Leukocyte receptor cluster member 9Add BLAST501

Proteomic databases

EPDiQ96B70
MaxQBiQ96B70
PaxDbiQ96B70
PeptideAtlasiQ96B70
PRIDEiQ96B70
ProteomicsDBi76052

PTM databases

iPTMnetiQ96B70
PhosphoSitePlusiQ96B70

Expressioni

Gene expression databases

CleanExiHS_LENG9

Organism-specific databases

HPAiHPA051671
HPA053556

Interactioni

Protein-protein interaction databases

BioGridi125106, 3 interactors
IntActiQ96B70, 2 interactors
MINTiQ96B70
STRINGi9606.ENSP00000331647

Structurei

3D structure databases

ProteinModelPortaliQ96B70
SMRiQ96B70
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri40 – 67C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IWVT Eukaryota
ENOG4111GEQ LUCA
HOGENOMiHOG000062983
HOVERGENiHBG068924
InParanoidiQ96B70
OrthoDBiEOG091G07VD
PhylomeDBiQ96B70
TreeFamiTF329287

Family and domain databases

InterProiView protein in InterPro
IPR009097 cNuc_Pdiesterase
IPR019510 Kinase-A_anchor_nucl_local_sig
IPR007547 UPF0248
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF10469 AKAP7_NLS, 1 hit
PF04457 DUF504, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF55144 SSF55144, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q96B70-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSRPPCGAT SSARRACQFP APMAAAREPE LPQEAPATEP APPPACRFFL
60 70 80 90 100
EGRCRFGARC RQPHPGAPAP PGREAQPEAG AKKPPLRTAA DVIQRIRWDP
110 120 130 140 150
RLDPADFSVG YVDRFLGVRE EPFSAFCWDQ PLAALGPGVL AVPQHRVRFF
160 170 180 190 200
RFHGRLVWDR ASRTDLVFGS GSAAGRGPTI LDAPNTEGAH GAEGAEWTLA
210 220 230 240 250
GTGQEAQAAP KRGSTRPLCT GHQEPGVEEP GELEAAQERA LGTAADLGTL
260 270 280 290 300
APRGRLAGVT EEALKPTAAT RTTLLGGKEA QALGVPGGSA ETTEAEWGPA
310 320 330 340 350
AWPEDKRARL SVAAPCQPRP THFVALMVTE PGLQAEVTKA QEYLVHVAPH
360 370 380 390 400
CANFLVPSQN LHLTLALLRL AGAGEEAAAI GALRRALLAP GLNAPPRLSF
410 420 430 440 450
RKLVLLGPHV LCAPPSPTLE SMAQVLSQRL EAEGLSTLQS PGQLHPHLTV
460 470 480 490 500
AKVPHGSQVH LPKLEFTLSQ EVGCQPLQTL WLCRIGRTGG PFQPLAEIRL

E
Length:501
Mass (Da):53,167
Last modified:May 18, 2010 - v2
Checksum:i6AF04904A6518554
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WVD1A0A087WVD1_HUMAN
Leukocyte receptor cluster member 9
LENG9
478Annotation score:

Sequence cautioni

The sequence AAH15921 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_029602153H → R. Corresponds to variant dbSNP:rs10406453Ensembl.1
Natural variantiVAR_029603499R → P. Corresponds to variant dbSNP:rs10423424Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008746 Genomic DNA No translation available.
CU207370 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72251.1
BC015921 mRNA Translation: AAH15921.1 Different initiation.
RefSeqiNP_945339.2, NM_198988.1
UniGeneiHs.590976

Genome annotation databases

EnsembliENST00000614111; ENSP00000483600; ENSG00000274495
ENST00000622419; ENSP00000477636; ENSG00000273574
GeneIDi94059
KEGGihsa:94059
UCSCiuc032jrx.2 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008746 Genomic DNA No translation available.
CU207370 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72251.1
BC015921 mRNA Translation: AAH15921.1 Different initiation.
RefSeqiNP_945339.2, NM_198988.1
UniGeneiHs.590976

3D structure databases

ProteinModelPortaliQ96B70
SMRiQ96B70
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125106, 3 interactors
IntActiQ96B70, 2 interactors
MINTiQ96B70
STRINGi9606.ENSP00000331647

PTM databases

iPTMnetiQ96B70
PhosphoSitePlusiQ96B70

Polymorphism and mutation databases

BioMutaiLENG9
DMDMi296434565

Proteomic databases

EPDiQ96B70
MaxQBiQ96B70
PaxDbiQ96B70
PeptideAtlasiQ96B70
PRIDEiQ96B70
ProteomicsDBi76052

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000614111; ENSP00000483600; ENSG00000274495
ENST00000622419; ENSP00000477636; ENSG00000273574
GeneIDi94059
KEGGihsa:94059
UCSCiuc032jrx.2 human

Organism-specific databases

CTDi94059
GeneCardsiLENG9
HGNCiHGNC:16306 LENG9
HPAiHPA051671
HPA053556
neXtProtiNX_Q96B70
PharmGKBiPA134975056
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IWVT Eukaryota
ENOG4111GEQ LUCA
HOGENOMiHOG000062983
HOVERGENiHBG068924
InParanoidiQ96B70
OrthoDBiEOG091G07VD
PhylomeDBiQ96B70
TreeFamiTF329287

Miscellaneous databases

GenomeRNAii94059
PROiPR:Q96B70

Gene expression databases

CleanExiHS_LENG9

Family and domain databases

InterProiView protein in InterPro
IPR009097 cNuc_Pdiesterase
IPR019510 Kinase-A_anchor_nucl_local_sig
IPR007547 UPF0248
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF10469 AKAP7_NLS, 1 hit
PF04457 DUF504, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF55144 SSF55144, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiLENG9_HUMAN
AccessioniPrimary (citable) accession number: Q96B70
Secondary accession number(s): B2VAM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: May 18, 2010
Last modified: June 20, 2018
This is version 116 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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Main funding by: National Institutes of Health

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