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Protein

BLOC-1-related complex subunit 7

Gene

BORCS7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.1 Publication

Miscellaneous

Diaskedin is from the ancient Greek diaskedazo, meaning to disperse.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
BLOC-1-related complex subunit 7Curated
Alternative name(s):
Diaskedin1 Publication
Gene namesi
Name:BORCS7Imported
Synonyms:C10orf32Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000166275.15
HGNCiHGNC:23516 BORCS7
MIMi616600 gene
neXtProtiNX_Q96B45

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Lysosome, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134928831

Polymorphism and mutation databases

BioMutaiC10orf32

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000897871 – 105BLOC-1-related complex subunit 7Add BLAST105

Proteomic databases

EPDiQ96B45
MaxQBiQ96B45
PaxDbiQ96B45
PeptideAtlasiQ96B45
PRIDEiQ96B45
ProteomicsDBi76044

PTM databases

iPTMnetiQ96B45
PhosphoSitePlusiQ96B45

Expressioni

Gene expression databases

BgeeiENSG00000166275
GenevisibleiQ96B45 HS

Organism-specific databases

HPAiHPA037648

Interactioni

Subunit structurei

Component of the BLOC-one-related complex (BORC) which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN.1 Publication

Protein-protein interaction databases

BioGridi125633, 19 interactors
IntActiQ96B45, 2 interactors
STRINGi9606.ENSP00000299353

Family & Domainsi

Sequence similaritiesi

Belongs to the BORCS7 family.Curated

Phylogenomic databases

eggNOGiENOG410IY48 Eukaryota
ENOG410XVXJ LUCA
HOGENOMiHOG000293245
HOVERGENiHBG054930
InParanoidiQ96B45
KOiK20821
OMAiIQEDAIL
OrthoDBiEOG091G11TK
PhylomeDBiQ96B45
TreeFamiTF314767

Family and domain databases

InterProiView protein in InterPro
IPR032143 BORCS7
PANTHERiPTHR31397 PTHR31397, 1 hit
PfamiView protein in Pfam
PF16088 BORCS7, 1 hit

Sequencei

Sequence statusi: Complete.

Q96B45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATGTPESQA RFGQSVKGLL TEKVTTCGTD VIALTKQVLK GSRSSELLGQ
60 70 80 90 100
AARNMVLQED AILHSEDSLR KMAIITTHLQ YQQEAIQKNV EQSSDLQDQL

NHLLK
Length:105
Mass (Da):11,564
Last modified:December 1, 2001 - v1
Checksum:iF123B34D1F10765A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK098071 mRNA Translation: BAG53576.1
AK311742 mRNA Translation: BAG34685.1
AL832477 mRNA Translation: CAI46115.1
AL358790 Genomic DNA No translation available.
BC015994 mRNA Translation: AAH15994.1
RefSeqiNP_001129672.1, NM_001136200.1
NP_653192.2, NM_144591.3
UniGeneiHs.34492

Genome annotation databases

EnsembliENST00000339834; ENSP00000342331; ENSG00000166275
ENST00000369883; ENSP00000358899; ENSG00000166275
GeneIDi119032
KEGGihsa:119032
UCSCiuc001kwh.3 human

Similar proteinsi

Entry informationi

Entry nameiBORC7_HUMAN
AccessioniPrimary (citable) accession number: Q96B45
Secondary accession number(s): B2R488, B3KUW4, C9K0X3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

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