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UniProtKB - Q96B23 (CR025_HUMAN)

Entry version 136 (07 Apr 2021)
Sequence version 3 (28 Mar 2018)
Previous versions | rss
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Protein

Uncharacterized protein C18orf25

Gene

C18orf25

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96B23

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C18orf25
Alternative name(s):
ARKadia-like protein 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C18orf25Imported
Synonyms:ARKL11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:28172, C18orf25

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96B23

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000152242.10

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		147339

Open Targets

More...OpenTargetsi		ENSG00000152242

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134919240

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96B23, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C18orf25

Domain mapping of disease mutations (DMDM)

More...DMDMi		209572602

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000793121 – 404Uncharacterized protein C18orf25Add BLAST404

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei66PhosphoserineCombined sources1
Modified residuei67PhosphoserineCombined sources1
Modified residuei143PhosphoserineCombined sources1
Modified residuei145PhosphoserineCombined sources1
Modified residuei147PhosphoserineBy similarity1
Modified residuei327PhosphoserineCombined sources1
Modified residuei328PhosphoserineCombined sources1
Modified residuei330PhosphoserineCombined sources1
Modified residuei347Omega-N-methylarginineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki358Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96B23

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96B23

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96B23

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96B23

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96B23

PeptideAtlas

More...PeptideAtlasi		Q96B23

PRoteomics IDEntifications database

More...PRIDEi		Q96B23

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		76036 [Q96B23-1]
76037 [Q96B23-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96B23

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96B23

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000152242, Expressed in buccal mucosa cell and 228 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96B23, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96B23, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000152242, Tissue enhanced (esophagus)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127053, 64 interactors

Protein interaction database and analysis system

More...IntActi		Q96B23, 38 interactors

Molecular INTeraction database

More...MINTi		Q96B23

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000481626

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96B23, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96B23

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili175 – 200Sequence analysisAdd BLAST26

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QUC3, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016167

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_056953_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96B23

Identification of Orthologs from Complete Genome Data

More...OMAi		ATWRTSE

Database of Orthologous Groups

More...OrthoDBi		1237164at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96B23

TreeFam database of animal gene trees

More...TreeFami		TF351299

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029306, RNF111_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15303, RNF111_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96B23-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKMEEAVGKV EELIESEAPP KASEQETAKE EDGSVELESQ VQKDGVADST 
        60         70         80         90        100
VISSMPCLLM ELRRDSSESQ LASTESDKPT TGRVYESDSS NHCMLSPSSS 
       110        120        130        140        150
GHLADSDTLS SAEENEPSQA ETAVEGDPSG VSGATVGRKS RRSRSESETS 
       160        170        180        190        200
TMAAKKNRQS SDKQNGRVAK VKGHRSQKHK ERIRLLRQKR EAAARKKYNL 
       210        220        230        240        250
LQDSSTSDSD LTCDSSTSSS DDDEEVSGSS KTITAEIPDG PPVVAHYDMS 
       260        270        280        290        300
DTNSDPEVVN VDNLLAAAVV QEHSNSVGGQ DTGATWRTSG LLEELNAEAG 
       310        320        330        340        350
HLDPGFLASD KTSAGNAPLN EEINIASSDS EVEIVGVQEH ARCVHPRGGV 
       360        370        380        390        400
IQSVSSWKHG SGTQYVSTRQ TQSWTAVTPQ QTWASPAEVV DLTLDEDSRR 

KYLL
Length:404
Mass (Da):43,395
Last modified:March 28, 2018 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9A3DC655FE41BA7E
GO
Isoform 2 (identifier: Q96B23-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     239-299: Missing.

Show »
Length:343
Mass (Da):37,048
Checksum:i85FBC054A3358B4E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EQH1K7EQH1_HUMAN
Uncharacterized protein C18orf25
C18orf25
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WVF1A0A087WVF1_HUMAN
Uncharacterized protein C18orf25
C18orf25
275Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ER64K7ER64_HUMAN
Uncharacterized protein C18orf25
C18orf25
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti233I → V in CAD89920 (PubMed:17974005).Curated1
Sequence conflicti316N → S in CAE45812 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_080245314Missing 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_014753239 – 299Missing in isoform 2. 3 PublicationsAdd BLAST61

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BK005125 mRNA Translation: DAA05329.1
AK289738 mRNA Translation: BAF82427.1
AK292981 mRNA Translation: BAF85670.1
AL713661 mRNA Translation: CAD28470.1
AL832027 mRNA Translation: CAD89920.1
BX640683 mRNA Translation: CAE45812.1
AC021763 Genomic DNA No translation available.
AC118647 Genomic DNA No translation available.
KF573673 Genomic DNA No translation available.
CH471088 Genomic DNA Translation: EAX01472.1
CH471088 Genomic DNA Translation: EAX01473.1
BC016149 mRNA Translation: AAH16149.1
BC084579 mRNA Translation: AAH84579.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS42430.1 [Q96B23-1]
CCDS42431.1 [Q96B23-2]

NCBI Reference Sequences

More...RefSeqi		NP_001008240.1, NM_001008239.2 [Q96B23-2]
NP_659492.1, NM_145055.3 [Q96B23-1]
XP_011524124.1, XM_011525822.1 [Q96B23-1]
XP_016881044.1, XM_017025555.1 [Q96B23-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000615052; ENSP00000481626; ENSG00000152242 [Q96B23-1]
ENST00000619301; ENSP00000480074; ENSG00000152242 [Q96B23-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		147339

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:147339

UCSC genome browser

More...UCSCi		uc032hdb.2, human
uc032hdc.2, human [Q96B23-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BK005125 mRNA Translation: DAA05329.1
AK289738 mRNA Translation: BAF82427.1
AK292981 mRNA Translation: BAF85670.1
AL713661 mRNA Translation: CAD28470.1
AL832027 mRNA Translation: CAD89920.1
BX640683 mRNA Translation: CAE45812.1
AC021763 Genomic DNA No translation available.
AC118647 Genomic DNA No translation available.
KF573673 Genomic DNA No translation available.
CH471088 Genomic DNA Translation: EAX01472.1
CH471088 Genomic DNA Translation: EAX01473.1
BC016149 mRNA Translation: AAH16149.1
BC084579 mRNA Translation: AAH84579.1
CCDSiCCDS42430.1 [Q96B23-1]
CCDS42431.1 [Q96B23-2]
RefSeqiNP_001008240.1, NM_001008239.2 [Q96B23-2]
NP_659492.1, NM_145055.3 [Q96B23-1]
XP_011524124.1, XM_011525822.1 [Q96B23-1]
XP_016881044.1, XM_017025555.1 [Q96B23-2]

3D structure databases

SMRiQ96B23
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127053, 64 interactors
IntActiQ96B23, 38 interactors
MINTiQ96B23
STRINGi9606.ENSP00000481626

PTM databases

iPTMnetiQ96B23
PhosphoSitePlusiQ96B23

Genetic variation databases

BioMutaiC18orf25
DMDMi209572602

Proteomic databases

EPDiQ96B23
jPOSTiQ96B23
MassIVEiQ96B23
MaxQBiQ96B23
PaxDbiQ96B23
PeptideAtlasiQ96B23
PRIDEiQ96B23
ProteomicsDBi76036 [Q96B23-1]
76037 [Q96B23-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		22461, 111 antibodies

The DNASU plasmid repository

More...DNASUi		147339

Genome annotation databases

EnsembliENST00000615052; ENSP00000481626; ENSG00000152242 [Q96B23-1]
ENST00000619301; ENSP00000480074; ENSG00000152242 [Q96B23-2]
GeneIDi147339
KEGGihsa:147339
UCSCiuc032hdb.2, human
uc032hdc.2, human [Q96B23-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		147339
DisGeNETi147339

GeneCards: human genes, protein and diseases

More...GeneCardsi		C18orf25
HGNCiHGNC:28172, C18orf25
HPAiENSG00000152242, Tissue enhanced (esophagus)
neXtProtiNX_Q96B23
OpenTargetsiENSG00000152242
PharmGKBiPA134919240
VEuPathDBiHostDB:ENSG00000152242.10

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502QUC3, Eukaryota
GeneTreeiENSGT00390000016167
HOGENOMiCLU_056953_0_0_1
InParanoidiQ96B23
OMAiATWRTSE
OrthoDBi1237164at2759
PhylomeDBiQ96B23
TreeFamiTF351299

Enzyme and pathway databases

PathwayCommonsiQ96B23

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		147339, 5 hits in 970 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		C18orf25, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		147339
PharosiQ96B23, Tdark

Protein Ontology

More...PROi		PR:Q96B23
RNActiQ96B23, protein

Gene expression databases

BgeeiENSG00000152242, Expressed in buccal mucosa cell and 228 other tissues
ExpressionAtlasiQ96B23, baseline and differential
GenevisibleiQ96B23, HS

Family and domain databases

InterProiView protein in InterPro
IPR029306, RNF111_N
PfamiView protein in Pfam
PF15303, RNF111_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCR025_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96B23
Secondary accession number(s): A8K123
, A8KAB6, Q5BIX2, Q5XG78, Q6N058, Q86TB5, Q8TCQ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: March 28, 2018
Last modified: April 7, 2021
This is version 136 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
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