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Entry version 118 (08 May 2019)
Sequence version 3 (14 Oct 2008)
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Protein

MARVEL domain-containing protein 3

Gene

MARVELD3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

As a component of tight junctions, plays a role in paracellular ion conductivity.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.64.6.1 the plasmolipin (plasmolipin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MARVEL domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MARVELD3
Synonyms:MRVLDC3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30525 MARVELD3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
614094 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96A59

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 226CytoplasmicSequence analysisAdd BLAST226
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei227 – 247HelicalSequence analysisAdd BLAST21
Topological domaini248 – 271ExtracellularSequence analysisAdd BLAST24
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21
Topological domaini293 – 300CytoplasmicSequence analysis8
Transmembranei301 – 321HelicalSequence analysisAdd BLAST21
Topological domaini322 – 360ExtracellularSequence analysisAdd BLAST39
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Topological domaini382 – 401CytoplasmicSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Membrane, Tight junction

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
91862

Open Targets

More...
OpenTargetsi
ENSG00000140832

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134986126

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MARVELD3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
209572737

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002715291 – 401MARVEL domain-containing protein 3Add BLAST401

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96A59

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96A59

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96A59

PeptideAtlas

More...
PeptideAtlasi
Q96A59

PRoteomics IDEntifications database

More...
PRIDEi
Q96A59

ProteomicsDB human proteome resource

More...
ProteomicsDBi
75920
75921 [Q96A59-2]

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q96A59

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96A59

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96A59

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000140832 Expressed in 127 organ(s), highest expression level in buccal mucosa cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96A59 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96A59 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043514
HPA045471

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96A59

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini193 – 386MARVELPROSITE-ProRule annotationAdd BLAST194

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi8 – 120Arg-richAdd BLAST113
Compositional biasi129 – 170Pro-richAdd BLAST42

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183102

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000290685

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96A59

KEGG Orthology (KO)

More...
KOi
K21099

Identification of Orthologs from Complete Genome Data

More...
OMAi
SQMRAPG

Database of Orthologous Groups

More...
OrthoDBi
1155000at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96A59

TreeFam database of animal gene trees

More...
TreeFami
TF332526

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008253 Marvel

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51225 MARVEL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96A59-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEDPSGAREP RARPRERDPG RRPHPDQGRT HDRPRDRPGD PRRKRSSDGN
60 70 80 90 100
RRRDGDRDPE RDQERDGNRD RNRDRERERE RERDPDRGPR RDTHRDAGPR
110 120 130 140 150
AGEHGVWEKP RQSRTRDGAR GLTWDAAAPP GPAPWEAPEP PQPQRKGDPG
160 170 180 190 200
RRRPESEPPS ERYLPSTPRP GREEVEYYQS EAEGLLECHK CKYLCTGRAC
210 220 230 240 250
CQMLEVLLNL LILACSSVSY SSTGGYTGIT SLGGIYYYQF GGAYSGFDGA
260 270 280 290 300
DGEKAQQLDV QFYQLKLPMV TVAMACSGAL TALCCLFVAM GVLRVPWHCP
310 320 330 340 350
LLLVTEGLLD MLIAGGYIPA LYFYFHYLSA AYGSPVCKER QALYQSKGYS
360 370 380 390 400
GFGCSFHGAD IGAGIFAALG IVVFALGAVL AIKGYRKVRK LKEKPAEMFE

F
Length:401
Mass (Da):44,911
Last modified:October 14, 2008 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2E90E20665A9EAD8
GO
Isoform 2 (identifier: Q96A59-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     199-401: ACCQMLEVLL...KEKPAEMFEF → GVVQIVEVVL...APEYLWSGTL

Note: No experimental confirmation available.Curated
Show »
Length:410
Mass (Da):45,972
Checksum:i010639810C3375B4
GO
Isoform 3 (identifier: Q96A59-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     102-148: GEHGVWEKPR...EPPQPQRKGD → VNPLRRDICP...TCALGEVWCR
     149-401: Missing.

Note: No experimental confirmation available.
Show »
Length:148
Mass (Da):17,704
Checksum:i9DC0FDC8F31C2D68
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KSM2J3KSM2_HUMAN
MARVEL domain-containing protein 3
MARVELD3
219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQK1H3BQK1_HUMAN
MARVEL domain-containing protein 3
MARVELD3
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 2 (identifier: Q96A59-2)
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti388Y → H in BAB71294 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02989360E → K2 PublicationsCorresponds to variant dbSNP:rs4788821Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_047541102 – 148GEHGV…QRKGD → VNPLRRDICPRPPGLDERRW NITSQRRKDSWNATNANTCA LGEVWCR in isoform 3. 1 PublicationAdd BLAST47
Alternative sequenceiVSP_047542149 – 401Missing in isoform 3. 1 PublicationAdd BLAST253
Alternative sequenceiVSP_022322199 – 401ACCQM…EMFEF → GVVQIVEVVLNGMVLICIVA SYFVLAGFSASFSSGGGFGN NYYSPFEGTELEQVRQLDQQ YTILRSPLIYGGVAVSLGLG VLTMGVLLQGAKSRTMLSGK WLLTEAAFSLLAAVGYCTGI GVYLHVALQINSTDTCKTRE RLYARKGLTWMDCQLAGTDG AAATFACLLVIMYGASVVLA LRSYREQKRYKGSREQPGSY SDAPEYLWSGTL in isoform 2. 1 PublicationAdd BLAST203

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK056842 mRNA Translation: BAB71294.1
AK292185 mRNA Translation: BAF84874.1
AK307585 mRNA No translation available.
AC009097 Genomic DNA No translation available.
BC011893 mRNA Translation: AAH11893.1
BC013376 mRNA Translation: AAH13376.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10904.1 [Q96A59-1]
CCDS32478.1 [Q96A59-2]
CCDS59270.1 [Q96A59-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001017967.2, NM_001017967.3 [Q96A59-2]
NP_001258258.1, NM_001271329.1 [Q96A59-3]
NP_443090.4, NM_052858.5 [Q96A59-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000268485; ENSP00000268485; ENSG00000140832 [Q96A59-1]
ENST00000299952; ENSP00000299952; ENSG00000140832 [Q96A59-2]
ENST00000565261; ENSP00000455845; ENSG00000140832 [Q96A59-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
91862

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:91862

UCSC genome browser

More...
UCSCi
uc002fat.5 human [Q96A59-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056842 mRNA Translation: BAB71294.1
AK292185 mRNA Translation: BAF84874.1
AK307585 mRNA No translation available.
AC009097 Genomic DNA No translation available.
BC011893 mRNA Translation: AAH11893.1
BC013376 mRNA Translation: AAH13376.1
CCDSiCCDS10904.1 [Q96A59-1]
CCDS32478.1 [Q96A59-2]
CCDS59270.1 [Q96A59-3]
RefSeqiNP_001017967.2, NM_001017967.3 [Q96A59-2]
NP_001258258.1, NM_001271329.1 [Q96A59-3]
NP_443090.4, NM_052858.5 [Q96A59-1]

3D structure databases

SMRiQ96A59
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi1.A.64.6.1 the plasmolipin (plasmolipin) family

PTM databases

CarbonylDBiQ96A59
iPTMnetiQ96A59
PhosphoSitePlusiQ96A59

Polymorphism and mutation databases

BioMutaiMARVELD3
DMDMi209572737

Proteomic databases

EPDiQ96A59
jPOSTiQ96A59
MaxQBiQ96A59
PeptideAtlasiQ96A59
PRIDEiQ96A59
ProteomicsDBi75920
75921 [Q96A59-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
91862
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000268485; ENSP00000268485; ENSG00000140832 [Q96A59-1]
ENST00000299952; ENSP00000299952; ENSG00000140832 [Q96A59-2]
ENST00000565261; ENSP00000455845; ENSG00000140832 [Q96A59-3]
GeneIDi91862
KEGGihsa:91862
UCSCiuc002fat.5 human [Q96A59-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
91862
DisGeNETi91862

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MARVELD3
HGNCiHGNC:30525 MARVELD3
HPAiHPA043514
HPA045471
MIMi614094 gene
neXtProtiNX_Q96A59
OpenTargetsiENSG00000140832
PharmGKBiPA134986126

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00950000183102
HOGENOMiHOG000290685
InParanoidiQ96A59
KOiK21099
OMAiSQMRAPG
OrthoDBi1155000at2759
PhylomeDBiQ96A59
TreeFamiTF332526

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
91862

Protein Ontology

More...
PROi
PR:Q96A59

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000140832 Expressed in 127 organ(s), highest expression level in buccal mucosa cell
ExpressionAtlasiQ96A59 baseline and differential
GenevisibleiQ96A59 HS

Family and domain databases

InterProiView protein in InterPro
IPR008253 Marvel
PROSITEiView protein in PROSITE
PS51225 MARVEL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMALD3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96A59
Secondary accession number(s): A8K820, H3BQM5, Q96MJ4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: October 14, 2008
Last modified: May 8, 2019
This is version 118 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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