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UniProtKB - Q96A49 (SYAP1_HUMAN)

Entry version 158 (02 Dec 2020)
Sequence version 1 (01 Dec 2001)
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Protein

Synapse-associated protein 1

Gene

SYAP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in adipocyte differentiation by promoting mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' after growth factor stimulation (PubMed:23300339).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96A49

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Synapse-associated protein 1Curated
Alternative name(s):
BSD domain-containing signal transducer and Akt interactor protein1 Publication
Short name:
BSTA1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYAP1Imported
ORF Names:PRO3113
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000169895.5

Human Gene Nomenclature Database

More...HGNCi		HGNC:16273, SYAP1

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96A49

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Cytoplasm, Golgi apparatus, Membrane, Postsynaptic cell membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi198 – 199FW → AA: Inhibits interaction with AKT1, mTORC2-mediated phosphorylation of AKT1 at 'Ser-473' and adipocyte differentiation. 1 Publication2

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000169895

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38107

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96A49, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SYAP1

Domain mapping of disease mutations (DMDM)

More...DMDMi		30580522

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000723551 – 352Synapse-associated protein 1Add BLAST352

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei248PhosphothreonineCombined sources1
Modified residuei269PhosphoserineCombined sources1
Modified residuei313PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated. Phosphorylation increases in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96A49

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96A49

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96A49

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96A49

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96A49

PeptideAtlas

More...PeptideAtlasi		Q96A49

PRoteomics IDEntifications database

More...PRIDEi		Q96A49

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		75912

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96A49

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q96A49

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96A49

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:23300339).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000169895, Expressed in adrenal tissue and 216 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96A49, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000169895, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via phosphorylated form and BSD domain) with AKT1; this interaction is enhanced in a mTORC2-mediated manner in response to epidermal growth factor (EGF) stimulation and activates AKT1 (PubMed:23300339).

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		125103, 47 interactors

Protein interaction database and analysis system

More...IntActi		Q96A49, 30 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000369500

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96A49, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1352
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Biological Magnetic Resonance Data Bank

More...BMRBi		Q96A49

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96A49

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q96A49

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini158 – 210BSDPROSITE-ProRule annotationAdd BLAST53

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4310, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000007662

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_046184_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96A49

Identification of Orthologs from Complete Genome Data

More...OMAi		FGSYLFN

Database of Orthologous Groups

More...OrthoDBi		782515at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96A49

TreeFam database of animal gene trees

More...TreeFami		TF319666

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.3970.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005607, BSD_dom
IPR035925, BSD_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03909, BSD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00751, BSD, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50858, BSD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96A49-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFRGLSSWLG LQQPVAGGGQ PNGDAPPEQP SETVAESAEE ELQQAGDQEL 
        60         70         80         90        100
LHQAKDFGNY LFNFASAATK KITESVAETA QTIKKSVEEG KIDGIIDKTI 
       110        120        130        140        150
IGDFQKEQKK FVEEQHTKKS EAAVPPWVDT NDEETIQQQI LALSADKRNF 
       160        170        180        190        200
LRDPPAGVQF NFDFDQMYPV ALVMLQEDEL LSKMRFALVP KLVKEEVFWR 
       210        220        230        240        250
NYFYRVSLIK QSAQLTALAA QQQAAGKEEK SNGREQDLPL AEAVRPKTPP 
       260        270        280        290        300
VVIKSQLKTQ EDEEEISTSP GVSEFVSDAF DACNLNQEDL RKEMEQLVLD 
       310        320        330        340        350
KKQEETAVLE EDSADWEKEL QQELQEYEVV TESEKRDENW DKEIEKMLQE 

EN
Length:352
Mass (Da):39,933
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2083636CF7CF75AE
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK55531 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti26P → L in AAH14657 (PubMed:15489334).Curated1
Sequence conflicti96I → T in BAB55087 (PubMed:14702039).Curated1
Sequence conflicti176Q → H in AAK55531 (PubMed:11483580).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF168955 mRNA Translation: AAK81893.1
AF338728 mRNA Translation: AAK69273.1
AK027401 mRNA Translation: BAB55087.1
CR749849 mRNA Translation: CAH18697.1
AL445467 Genomic DNA No translation available.
CH471074 Genomic DNA Translation: EAW98917.1
BC014657 mRNA Translation: AAH14657.1
AF305828 mRNA Translation: AAK55531.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS14177.1

NCBI Reference Sequences

More...RefSeqi		NP_116185.2, NM_032796.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000380155; ENSP00000369500; ENSG00000169895

Database of genes from NCBI RefSeq genomes

More...GeneIDi		94056

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:94056

UCSC genome browser

More...UCSCi		uc004cxp.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF168955 mRNA Translation: AAK81893.1
AF338728 mRNA Translation: AAK69273.1
AK027401 mRNA Translation: BAB55087.1
CR749849 mRNA Translation: CAH18697.1
AL445467 Genomic DNA No translation available.
CH471074 Genomic DNA Translation: EAW98917.1
BC014657 mRNA Translation: AAH14657.1
AF305828 mRNA Translation: AAK55531.1 Different initiation.
CCDSiCCDS14177.1
RefSeqiNP_116185.2, NM_032796.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1X3ANMR-A130-216[»]
BMRBiQ96A49
SMRiQ96A49
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi125103, 47 interactors
IntActiQ96A49, 30 interactors
STRINGi9606.ENSP00000369500

PTM databases

iPTMnetiQ96A49
MetOSiteiQ96A49
PhosphoSitePlusiQ96A49

Polymorphism and mutation databases

BioMutaiSYAP1
DMDMi30580522

Proteomic databases

EPDiQ96A49
jPOSTiQ96A49
MassIVEiQ96A49
MaxQBiQ96A49
PaxDbiQ96A49
PeptideAtlasiQ96A49
PRIDEiQ96A49
ProteomicsDBi75912

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		395, 124 antibodies

The DNASU plasmid repository

More...DNASUi		94056

Genome annotation databases

EnsembliENST00000380155; ENSP00000369500; ENSG00000169895
GeneIDi94056
KEGGihsa:94056
UCSCiuc004cxp.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		94056
EuPathDBiHostDB:ENSG00000169895.5

GeneCards: human genes, protein and diseases

More...GeneCardsi		SYAP1
HGNCiHGNC:16273, SYAP1
HPAiENSG00000169895, Low tissue specificity
neXtProtiNX_Q96A49
OpenTargetsiENSG00000169895
PharmGKBiPA38107

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4310, Eukaryota
GeneTreeiENSGT00390000007662
HOGENOMiCLU_046184_1_1_1
InParanoidiQ96A49
OMAiFGSYLFN
OrthoDBi782515at2759
PhylomeDBiQ96A49
TreeFamiTF319666

Enzyme and pathway databases

PathwayCommonsiQ96A49

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		94056, 8 hits in 475 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SYAP1, human
EvolutionaryTraceiQ96A49

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		SYAP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		94056
PharosiQ96A49, Tdark

Protein Ontology

More...PROi		PR:Q96A49
RNActiQ96A49, protein

Gene expression databases

BgeeiENSG00000169895, Expressed in adrenal tissue and 216 other tissues
GenevisibleiQ96A49, HS

Family and domain databases

Gene3Di1.10.3970.10, 1 hit
InterProiView protein in InterPro
IPR005607, BSD_dom
IPR035925, BSD_dom_sf
PfamiView protein in Pfam
PF03909, BSD, 1 hit
SMARTiView protein in SMART
SM00751, BSD, 1 hit
PROSITEiView protein in PROSITE
PS50858, BSD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYAP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96A49
Secondary accession number(s): Q68CP1
, Q96C60, Q96JQ6, Q96T20
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 9, 2003
Last sequence update: December 1, 2001
Last modified: December 2, 2020
This is version 158 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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