MARC2

Functionⁱ

As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.1 Publication

Cofactorⁱ

Mo-molybdopterin1 PublicationNote: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.1 Publication

Keywordsⁱ

Molecular function	Oxidoreductase
Ligand	Molybdenum

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211945 Phase I - Functionalization of compounds

Reactomeⁱ

R-HSA-211945 Phase I - Functionalization of compounds

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Mitochondrial amidoxime reducing component 2 (EC:1.-.-.-) Short name: mARC2 Alternative name(s): Molybdenum cofactor sulfurase C-terminal domain-containing protein 2 Short name: MOSC domain-containing protein 2 Short name: Moco sulfurase C-terminal domain-containing protein 2
Gene namesⁱ	Name:MARC2 Synonyms:MOSC2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000117791.15
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:26064 MARC2
MIMⁱ	614127 gene
neXtProtⁱ	NX_Q969Z3

Keywords - Cellular componentⁱ

Membrane, Mitochondrion, Mitochondrion outer membrane, Peroxisome

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	54996
Open Targets More...OpenTargetsⁱ	ENSG00000117791
PharmGKBⁱ	PA142671345

Polymorphism and mutation databases

BioMutaⁱ	MARC2
DMDMⁱ	74760692

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transit peptideⁱ	1 – 35	MitochondrionSequence analysisAdd BLAST		35
ChainⁱPRO_0000273340	36 – 335	Mitochondrial amidoxime reducing component 2Add BLAST		300

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Cross-linkⁱ	59	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	138	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	144	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Modified residueⁱ	156	N6-acetyllysine; alternateBy similarity	1
Cross-linkⁱ	156	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate1 Publication
Cross-linkⁱ	166	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	173	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	187	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	287	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication
Cross-linkⁱ	294	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)1 Publication

Post-translational modificationⁱ

Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.1 Publication

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

EPDⁱ	Q969Z3
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q969Z3
PaxDbⁱ	Q969Z3
PeptideAtlas More...PeptideAtlasⁱ	Q969Z3
PRIDEⁱ	Q969Z3
ProteomicsDBⁱ	75882 75883 [Q969Z3-2]

PTM databases

iPTMnetⁱ	Q969Z3
PhosphoSitePlusⁱ	Q969Z3

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000117791 Expressed in 212 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_MOSC2
ExpressionAtlasⁱ	Q969Z3 baseline and differential
Genevisibleⁱ	Q969Z3 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA015085 HPA017572

HPAⁱ

HPA015085
HPA017572

Interactionⁱ

Subunit structureⁱ

Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MARC2.By similarity

Protein-protein interaction databases

BioGridⁱ	120329, 5 interactors
IntActⁱ	Q969Z3, 4 interactors
STRINGⁱ	9606.ENSP00000355880

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q969Z3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	188 – 334	MOSCPROSITE-ProRule annotationAdd BLAST		147

Keywords - Domainⁱ

Transit peptide

Phylogenomic databases

eggNOGⁱ	KOG2362 Eukaryota COG3217 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063150
HOVERGENⁱ	HBG081982
InParanoidⁱ	Q969Z3
OMAⁱ	ARQYPQM
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0S9F
PhylomeDBⁱ	Q969Z3
TreeFamⁱ	TF316807

Family and domain databases

InterProⁱ	View protein in InterPro IPR005302 MoCF_Sase_C IPR005303 MOSC_N IPR011037 Pyrv_Knase-like_insert_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03473 MOSC, 1 hit PF03476 MOSC_N, 1 hit
SUPFAMⁱ	SSF50800 SSF50800, 2 hits
PROSITEⁱ	View protein in PROSITE PS51340 MOSC, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q969Z3-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGASSSSALA RLGLPARPWP RWLGVAALGL AAVALGTVAW RRAWPRRRRR 
        60         70         80         90        100
LQQVGTVAKL WIYPVKSCKG VPVSEAECTA MGLRSGNLRD RFWLVIKEDG 
       110        120        130        140        150
HMVTARQEPR LVLISIIYEN NCLIFRAPDM DQLVLPSKQP SSNKLHNCRI 
       160        170        180        190        200
FGLDIKGRDC GNEAAKWFTN FLKTEAYRLV QFETNMKGRT SRKLLPTLDQ 
       210        220        230        240        250
NFQVAYPDYC PLLIMTDASL VDLNTRMEKK MKMENFRPNI VVTGCDAFEE 
       260        270        280        290        300
DTWDELLIGS VEVKKVMACP RCILTTVDPD TGVIDRKQPL DTLKSYRLCD 
       310        320        330 
PSERELYKLS PLFGIYYSVE KIGSLRVGDP VYRMV

Length:335

Mass (Da):38,023

Last modified:December 1, 2001 - v1

Checksum:ⁱ4C6A9B8B9AC0F74D

GO

Isoform 2 (identifier: Q969Z3-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
251-257: DTWDELL → ASATRRD
258-335: Missing.

« Hide

        10         20         30         40         50
MGASSSSALA RLGLPARPWP RWLGVAALGL AAVALGTVAW RRAWPRRRRR 
        60         70         80         90        100
LQQVGTVAKL WIYPVKSCKG VPVSEAECTA MGLRSGNLRD RFWLVIKEDG 
       110        120        130        140        150
HMVTARQEPR LVLISIIYEN NCLIFRAPDM DQLVLPSKQP SSNKLHNCRI 
       160        170        180        190        200
FGLDIKGRDC GNEAAKWFTN FLKTEAYRLV QFETNMKGRT SRKLLPTLDQ 
       210        220        230        240        250
NFQVAYPDYC PLLIMTDASL VDLNTRMEKK MKMENFRPNI VVTGCDAFEE 

ASATRRD

Note: No experimental confirmation available.

Show »

Length:257

Mass (Da):29,103

Checksum:ⁱ8938E1231A0ACB9B

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

X1WI34	X1WI34_HUMAN	Mitochondrial amidoxime reducing co... Mitochondrial amidoxime reducing component 2	MARC2	172	Annotation score:
F6V6Z1	F6V6Z1_HUMAN	Mitochondrial amidoxime reducing co... Mitochondrial amidoxime reducing component 2	MARC2	94	Annotation score:

Sequence cautionⁱ

The sequence BAA91287 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	169	T → A in CAL38507 (PubMed:17974005).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_062275	3	A → S1 PublicationCorresponds to variant dbSNP:rs72472370Ensembl.	1
Natural variantⁱVAR_030133	244	G → S Decreased catalytic efficiency toward benzamidoxime; no effect on affinity for benzamidoxime; no effect on binding of the molybdenum cofactor. 2 PublicationsCorresponds to variant dbSNP:rs3795535Ensembl.	1
Natural variantⁱVAR_070777	245	C → W Decreased catalytic activity toward benzamidoxime; no effect on affinity for benzamidoxime; no effect on binding of the molybdenum cofactor. 1 PublicationCorresponds to variant dbSNP:rs76664695Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_022513	251 – 257	DTWDELL → ASATRRD in isoform 2. 1 Publication		7
Alternative sequenceⁱVSP_022514	258 – 335	Missing in isoform 2. 1 PublicationAdd BLAST		78

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL136931 mRNA Translation: CAB66865.1 AM393631 mRNA Translation: CAL38507.1 EU567145 Genomic DNA Translation: ACB21048.1 AL359353 Genomic DNA No translation available. AL606726 Genomic DNA No translation available. CH471100 Genomic DNA Translation: EAW93293.1 CH471100 Genomic DNA Translation: EAW93294.1 BC011973 mRNA Translation: AAH11973.1 BC015829 mRNA Translation: AAH15829.2 BC016859 mRNA Translation: AAH16859.1 AK000612 mRNA Translation: BAA91287.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS1525.1 [Q969Z3-1] CCDS81425.1 [Q969Z3-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001304267.1, NM_001317338.1 [Q969Z3-1] NP_001317971.1, NM_001331042.1 [Q969Z3-2] NP_060368.2, NM_017898.4 [Q969Z3-1]
UniGeneⁱ	Hs.369042

Genome annotation databases

Ensemblⁱ	ENST00000359316; ENSP00000352266; ENSG00000117791 [Q969Z3-2] ENST00000366913; ENSP00000355880; ENSG00000117791 [Q969Z3-1]
GeneIDⁱ	54996
KEGGⁱ	hsa:54996
UCSC genome browser More...UCSCⁱ	uc001hmq.4 human [Q969Z3-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q969Z3	Mitochondrial amidoxime reducing component 2 (Fragment)		HUMAN		172	UniRef100_Q969Z3

Protein	Similar proteins		Species	Score	Length	Source
Q969Z3	Mitochondrial amidoxime reducing component 2		MACFA		335	UniRef90_Q969Z3
Mitochondrial amidoxime reducing component 2 (Fragment)		HUMAN		172
MOSC domain-containing protein 2, mitochondrial		MACMU		335
MARC2 isoform 1		PANTR		335
Uncharacterized protein		COLAP		335
+20
Q969Z3-2	MARC2 isoform 2		PANTR		257	UniRef90_Q969Z3-2
Uncharacterized protein		COLAP		257
MARC2 isoform 2		PONAB		257
Uncharacterized protein		CERAT		257
Uncharacterized protein		RHIRO		257
+9

Protein	Similar proteins		Species	Score	Length	Source
Q969Z3	Mitochondrial amidoxime-reducing component 1		HUMAN		337	UniRef50_Q5VT66
Mitochondrial amidoxime reducing component 2		MOUSE		338
Mitochondrial amidoxime reducing component 2		RAT		338
Mitochondrial amidoxime reducing component 2		MACFA		335
Mitochondrial amidoxime reducing component 2		BOVIN		336
+263
Q969Z3-2	Uncharacterized protein		RHIRO		257	UniRef50_Q969Z3-2
Uncharacterized protein		COLAP		257
Mitochondrial amidoxime reducing component 2		GORGO		257
Uncharacterized protein		RHIBE		257
Uncharacterized protein		CERAT		257
+17

Cross-referencesⁱ

Web resourcesⁱ

NIEHS-SNPs

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL136931 mRNA Translation: CAB66865.1 AM393631 mRNA Translation: CAL38507.1 EU567145 Genomic DNA Translation: ACB21048.1 AL359353 Genomic DNA No translation available. AL606726 Genomic DNA No translation available. CH471100 Genomic DNA Translation: EAW93293.1 CH471100 Genomic DNA Translation: EAW93294.1 BC011973 mRNA Translation: AAH11973.1 BC015829 mRNA Translation: AAH15829.2 BC016859 mRNA Translation: AAH16859.1 AK000612 mRNA Translation: BAA91287.1 Different initiation.
CCDSⁱ	CCDS1525.1 [Q969Z3-1] CCDS81425.1 [Q969Z3-2]
RefSeqⁱ	NP_001304267.1, NM_001317338.1 [Q969Z3-1] NP_001317971.1, NM_001331042.1 [Q969Z3-2] NP_060368.2, NM_017898.4 [Q969Z3-1]
UniGeneⁱ	Hs.369042

3D structure databases

ProteinModelPortalⁱ	Q969Z3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	120329, 5 interactors
IntActⁱ	Q969Z3, 4 interactors
STRINGⁱ	9606.ENSP00000355880

PTM databases

iPTMnetⁱ	Q969Z3
PhosphoSitePlusⁱ	Q969Z3

Polymorphism and mutation databases

BioMutaⁱ	MARC2
DMDMⁱ	74760692

Proteomic databases

EPDⁱ	Q969Z3
MaxQBⁱ	Q969Z3
PaxDbⁱ	Q969Z3
PeptideAtlasⁱ	Q969Z3
PRIDEⁱ	Q969Z3
ProteomicsDBⁱ	75882 75883 [Q969Z3-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	54996
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000359316; ENSP00000352266; ENSG00000117791 [Q969Z3-2] ENST00000366913; ENSP00000355880; ENSG00000117791 [Q969Z3-1]
GeneIDⁱ	54996
KEGGⁱ	hsa:54996
UCSCⁱ	uc001hmq.4 human [Q969Z3-1]

Organism-specific databases

CTDⁱ	54996
DisGeNETⁱ	54996
EuPathDBⁱ	HostDB:ENSG00000117791.15
GeneCardsⁱ	MARC2
HGNCⁱ	HGNC:26064 MARC2
HPAⁱ	HPA015085 HPA017572
MIMⁱ	614127 gene
neXtProtⁱ	NX_Q969Z3
OpenTargetsⁱ	ENSG00000117791
PharmGKBⁱ	PA142671345
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2362 Eukaryota COG3217 LUCA
GeneTreeⁱ	ENSGT00530000063150
HOVERGENⁱ	HBG081982
InParanoidⁱ	Q969Z3
OMAⁱ	ARQYPQM
OrthoDBⁱ	EOG091G0S9F
PhylomeDBⁱ	Q969Z3
TreeFamⁱ	TF316807

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211945 Phase I - Functionalization of compounds

Reactomeⁱ

R-HSA-211945 Phase I - Functionalization of compounds

Miscellaneous databases

ChiTaRSⁱ	MARC2 human
GeneWikiⁱ	MOSC2
GenomeRNAiⁱ	54996
Protein Ontology More...PROⁱ	PR:Q969Z3
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000117791 Expressed in 212 organ(s), highest expression level in left lobe of thyroid gland
CleanExⁱ	HS_MOSC2
ExpressionAtlasⁱ	Q969Z3 baseline and differential
Genevisibleⁱ	Q969Z3 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR005302 MoCF_Sase_C IPR005303 MOSC_N IPR011037 Pyrv_Knase-like_insert_dom_sf
Pfamⁱ	View protein in Pfam PF03473 MOSC, 1 hit PF03476 MOSC_N, 1 hit
SUPFAMⁱ	SSF50800 SSF50800, 2 hits
PROSITEⁱ	View protein in PROSITE PS51340 MOSC, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MARC2_HUMAN
Accessionⁱ	Q969Z3Primary (citable) accession number: Q969Z3 Secondary accession number(s): B2D0R5 Q9NWU0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
	Last sequence update:	December 1, 2001
	Last modified:	September 12, 2018
	This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q969Z3 (MARC2_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Mitochondrial amidoxime reducing component 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Peroxisome

Mitochondrion

Mitochondrion

Peroxisome

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

Kineticsⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ