Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Due to a server migration, the UniProt 'ID mapping', 'Peptide search' and 'community bibliography submission' tools will not be available on the 19th April 2021 during the morning (EST).

UniProtKB - Q969S0 (S35B4_HUMAN)

Entry version 154 (07 Apr 2021)
Sequence version 1 (01 Dec 2001)
Previous versions | rss
Add a publicationFeedback
Protein

UDP-xylose and UDP-N-acetylglucosamine transporter

Gene

SLC35B4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q969S0

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-727802, Transport of nucleotide sugars

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.7.10.2, the drug/metabolite transporter (dmt) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
UDP-xylose and UDP-N-acetylglucosamine transporter
Alternative name(s):
Solute carrier family 35 member B4
YEA4 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC35B4
Synonyms:YEA4
ORF Names:PSEC0055
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20584, SLC35B4

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610923, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q969S0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000205060.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
Transmembranei59 – 79HelicalSequence analysisAdd BLAST21
Transmembranei92 – 112HelicalSequence analysisAdd BLAST21
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Transmembranei201 – 221HelicalSequence analysisAdd BLAST21
Transmembranei229 – 249HelicalSequence analysisAdd BLAST21
Transmembranei251 – 267HelicalSequence analysisAdd BLAST17
Transmembranei268 – 288HelicalSequence analysisAdd BLAST21
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		84912

Open Targets

More...OpenTargetsi		ENSG00000205060

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134922110

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q969S0, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLC35B4

Domain mapping of disease mutations (DMDM)

More...DMDMi		74751727

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002133851 – 331UDP-xylose and UDP-N-acetylglucosamine transporterAdd BLAST331

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q969S0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q969S0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q969S0

PeptideAtlas

More...PeptideAtlasi		Q969S0

PRoteomics IDEntifications database

More...PRIDEi		Q969S0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		75824 [Q969S0-1]
75825 [Q969S0-2]
75826 [Q969S0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q969S0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q969S0

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q969S0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000205060, Expressed in middle temporal gyrus and 210 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q969S0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q969S0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000205060, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124349, 36 interactors

Protein interaction database and analysis system

More...IntActi		Q969S0, 33 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000367770

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q969S0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1583, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000002915

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_033007_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q969S0

Identification of Orthologs from Complete Genome Data

More...OMAi		NNYAFDF

Database of Orthologous Groups

More...OrthoDBi		1209974at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q969S0

TreeFam database of animal gene trees

More...TreeFami		TF312926

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013657, UAA

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08449, UAA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q969S0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRPALAVGLV FAGCCSNVIF LELLARKHPG CGNIVTFAQF LFIAVEGFLF 
        60         70         80         90        100
EADLGRKPPA IPIRYYAIMV TMFFTVSVVN NYALNLNIAM PLHMIFRSGS 
       110        120        130        140        150
LIANMILGII ILKKRYSIFK YTSIALVSVG IFICTFMSAK QVTSQSSLSE 
       160        170        180        190        200
NDGFQAFVWW LLGIGALTFA LLMSARMGIF QETLYKRFGK HSKEALFYNH 
       210        220        230        240        250
ALPLPGFVFL ASDIYDHAVL FNKSELYEIP VIGVTLPIMW FYLLMNIITQ 
       260        270        280        290        300
YVCIRGVFIL TTECASLTVT LVVTLRKFVS LIFSILYFQN PFTLWHWLGT 
       310        320        330 
LFVFIGTLMY TEVWNNLGTT KSEPQKDSKK N
Length:331
Mass (Da):37,424
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8C305DE30EFD4F82
GO
Isoform 2 (identifier: Q969S0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     225-231: ELYEIPV → GEFGVRQ
     232-331: Missing.

Show »
Length:231
Mass (Da):25,739
Checksum:i9FB3C66ACF052788
GO
Isoform 3 (identifier: Q969S0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     251-253: YVC → TPT
     254-331: Missing.

Show »
Length:253
Mass (Da):28,357
Checksum:iB58AEBAECC3CE6FA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WAW0F8WAW0_HUMAN
UDP-xylose and UDP-N-acetylglucosam...
SLC35B4
132Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB55325 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti21L → P in BAD96594 (Ref. 6) Curated1
Sequence conflicti119F → S in BAD96594 (Ref. 6) Curated1
Sequence conflicti179I → M in BAD96594 (Ref. 6) Curated1
Sequence conflicti205P → S in BAD96594 (Ref. 6) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016197225 – 231ELYEIPV → GEFGVRQ in isoform 2. 1 Publication7
Alternative sequenceiVSP_016198232 – 331Missing in isoform 2. 1 PublicationAdd BLAST100
Alternative sequenceiVSP_016199251 – 253YVC → TPT in isoform 3. 1 Publication3
Alternative sequenceiVSP_016200254 – 331Missing in isoform 3. 1 PublicationAdd BLAST78

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ971941 mRNA Translation: CAI98963.1
AB052892 mRNA Translation: BAB61040.1
AJ315497 mRNA Translation: CAC84567.1
AJ315498 mRNA Translation: CAC84568.1
AK027603 mRNA Translation: BAB55225.1
AK027726 mRNA Translation: BAB55325.1 Different initiation.
AK075368 mRNA Translation: BAC11573.1
AK222874 mRNA Translation: BAD96594.1
AC008154 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24071.1
CH471070 Genomic DNA Translation: EAW83810.1
BC008413 mRNA Translation: AAH08413.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS34756.1 [Q969S0-1]

NCBI Reference Sequences

More...RefSeqi		NP_116215.1, NM_032826.4 [Q969S0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000378509; ENSP00000367770; ENSG00000205060 [Q969S0-1]
ENST00000470969; ENSP00000485857; ENSG00000205060 [Q969S0-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		84912

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:84912

UCSC genome browser

More...UCSCi		uc003vrn.4, human [Q969S0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ971941 mRNA Translation: CAI98963.1
AB052892 mRNA Translation: BAB61040.1
AJ315497 mRNA Translation: CAC84567.1
AJ315498 mRNA Translation: CAC84568.1
AK027603 mRNA Translation: BAB55225.1
AK027726 mRNA Translation: BAB55325.1 Different initiation.
AK075368 mRNA Translation: BAC11573.1
AK222874 mRNA Translation: BAD96594.1
AC008154 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24071.1
CH471070 Genomic DNA Translation: EAW83810.1
BC008413 mRNA Translation: AAH08413.1
CCDSiCCDS34756.1 [Q969S0-1]
RefSeqiNP_116215.1, NM_032826.4 [Q969S0-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124349, 36 interactors
IntActiQ969S0, 33 interactors
STRINGi9606.ENSP00000367770

Protein family/group databases

TCDBi2.A.7.10.2, the drug/metabolite transporter (dmt) superfamily

PTM databases

iPTMnetiQ969S0
PhosphoSitePlusiQ969S0
SwissPalmiQ969S0

Genetic variation databases

BioMutaiSLC35B4
DMDMi74751727

Proteomic databases

MassIVEiQ969S0
MaxQBiQ969S0
PaxDbiQ969S0
PeptideAtlasiQ969S0
PRIDEiQ969S0
ProteomicsDBi75824 [Q969S0-1]
75825 [Q969S0-2]
75826 [Q969S0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		53731, 34 antibodies

Genome annotation databases

EnsembliENST00000378509; ENSP00000367770; ENSG00000205060 [Q969S0-1]
ENST00000470969; ENSP00000485857; ENSG00000205060 [Q969S0-2]
GeneIDi84912
KEGGihsa:84912
UCSCiuc003vrn.4, human [Q969S0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		84912
DisGeNETi84912

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLC35B4
HGNCiHGNC:20584, SLC35B4
HPAiENSG00000205060, Low tissue specificity
MIMi610923, gene
neXtProtiNX_Q969S0
OpenTargetsiENSG00000205060
PharmGKBiPA134922110
VEuPathDBiHostDB:ENSG00000205060.10

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1583, Eukaryota
GeneTreeiENSGT00390000002915
HOGENOMiCLU_033007_1_0_1
InParanoidiQ969S0
OMAiNNYAFDF
OrthoDBi1209974at2759
PhylomeDBiQ969S0
TreeFamiTF312926

Enzyme and pathway databases

PathwayCommonsiQ969S0
ReactomeiR-HSA-727802, Transport of nucleotide sugars

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		84912, 6 hits in 992 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLC35B4, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		SLC35B4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		84912
PharosiQ969S0, Tbio

Protein Ontology

More...PROi		PR:Q969S0
RNActiQ969S0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000205060, Expressed in middle temporal gyrus and 210 other tissues
ExpressionAtlasiQ969S0, baseline and differential
GenevisibleiQ969S0, HS

Family and domain databases

InterProiView protein in InterPro
IPR013657, UAA
PfamiView protein in Pfam
PF08449, UAA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS35B4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q969S0
Secondary accession number(s): A4D1P3
, A6NNS4, Q53GQ7, Q8TCU7, Q96K33
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: December 1, 2001
Last modified: April 7, 2021
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again