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Entry version 137 (16 Oct 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Protein YIPF5

Gene

YIPF5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in transport between endoplasmic reticulum and Golgi.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein YIPF5
Alternative name(s):
Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5
Smooth muscle cell-associated protein 5
Short name:
SMAP-5
YIP1 family member 5
YPT-interacting protein 1 A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:YIPF5
Synonyms:FINGER5, YIP1A
ORF Names:PP12723, SB140, UNQ3123/PRO10275
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:24877 YIPF5

Online Mendelian Inheritance in Man (OMIM)

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MIMi
611483 gene

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q969M3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 124Cytoplasmic1 PublicationAdd BLAST124
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei125 – 145HelicalSequence analysisAdd BLAST21
Topological domaini146LumenalCurated1
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 173CytoplasmicCurated6
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 196LumenalCurated2
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 236CytoplasmicCuratedAdd BLAST19
Transmembranei237 – 257HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
81555

Open Targets

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OpenTargetsi
ENSG00000145817

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670548

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q969M3

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
YIPF5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74760683

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002343281 – 257Protein YIPF5Add BLAST257

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q969M3

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q969M3

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q969M3

MaxQB - The MaxQuant DataBase

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MaxQBi
Q969M3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q969M3

PeptideAtlas

More...
PeptideAtlasi
Q969M3

PRoteomics IDEntifications database

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PRIDEi
Q969M3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
75792 [Q969M3-1]
75793 [Q969M3-2]
75794 [Q969M3-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q969M3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q969M3

SwissPalm database of S-palmitoylation events

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SwissPalmi
Q969M3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed. Highly expressed in coronary smooth muscles.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By TGFB1.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000145817 Expressed in 222 organ(s), highest expression level in nasal cavity mucosa

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q969M3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q969M3 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042338
HPA073622

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with the COPII coat components Sec23 (SEC23A and/or SEC23B) and Sec24 (SEC24A and/or SEC24B) (PubMed:11489904).

Interacts with YIF1A (PubMed:15990086). May interact with RAB1A (PubMed:15611160).

Interacts with YIPF3 and YIPF4 (PubMed:27999994).

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
123519, 55 interactors

Protein interaction database and analysis system

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IntActi
Q969M3, 61 interactors

Molecular INTeraction database

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MINTi
Q969M3

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000274496

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni75 – 106Interaction with Sec23Add BLAST32

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the YIP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3103 Eukaryota
COG5080 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00940000153168

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q969M3

KEGG Orthology (KO)

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KOi
K20363

Identification of Orthologs from Complete Genome Data

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OMAi
HPLKAAD

Database of Orthologous Groups

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OrthoDBi
1457080at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q969M3

TreeFam database of animal gene trees

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TreeFami
TF313100

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR006977 Yip1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04893 Yip1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q969M3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGFENLNTD FYQTSYSIDD QSQQSYDYGG SGGPYSKQYA GYDYSQQGRF
60 70 80 90 100
VPPDMMQPQQ PYTGQIYQPT QAYTPASPQP FYGNNFEDEP PLLEELGINF
110 120 130 140 150
DHIWQKTLTV LHPLKVADGS IMNETDLAGP MVFCLAFGAT LLLAGKIQFG
160 170 180 190 200
YVYGISAIGC LGMFCLLNLM SMTGVSFGCV ASVLGYCLLP MILLSSFAVI
210 220 230 240 250
FSLQGMVGII LTAGIIGWCS FSASKIFISA LAMEGQQLLV AYPCALLYGV

FALISVF
Length:257
Mass (Da):27,989
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB30EACB0E514DC67
GO
Isoform 2 (identifier: Q969M3-2) [UniParc]FASTAAdd to basket
Also known as: D

The sequence of this isoform differs from the canonical sequence as follows:
     1-54: Missing.

Show »
Length:203
Mass (Da):21,896
Checksum:iC29C76D8D3D7FF6F
GO
Isoform 3 (identifier: Q969M3-3) [UniParc]FASTAAdd to basket
Also known as: I

The sequence of this isoform differs from the canonical sequence as follows:
     242-257: YPCALLYGVFALISVF → LQPNITYGSNYFLFCCLPYPQQHF

Show »
Length:265
Mass (Da):29,107
Checksum:iDBAD311C26DE5A05
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RHH4E5RHH4_HUMAN
Protein YIPF
YIPF5
177Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGR9E5RGR9_HUMAN
Protein YIPF5
YIPF5
101Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti136 – 138AFG → DLA in AAK67644 (Ref. 3) Curated3
Sequence conflicti155I → S in AAG48521 (PubMed:11489904).Curated1
Sequence conflicti187C → W in AAK67644 (Ref. 3) Curated1
Sequence conflicti192I → Y in AAG48521 (PubMed:11489904).Curated1
Sequence conflicti244C → R in BAD97235 (Ref. 7) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0182531 – 54Missing in isoform 2. 1 PublicationAdd BLAST54
Alternative sequenceiVSP_018254242 – 257YPCAL…LISVF → LQPNITYGSNYFLFCCLPYP QQHF in isoform 3. 1 PublicationAdd BLAST16

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF140225 mRNA Translation: AAG48521.1
AY640925 mRNA Translation: AAV51256.1
AY640926 mRNA Translation: AAV51257.1
AY640927 mRNA Translation: AAV51258.1
AY640928 mRNA Translation: AAV51259.1
AY640929 mRNA No translation available.
AY640934 mRNA Translation: AAV51260.1
AY037152 mRNA Translation: AAK67644.1
AY358863 mRNA Translation: AAQ89222.1
AK054576 mRNA Translation: BAB70763.1
AF318329 mRNA Translation: AAL55836.1
AK223515 mRNA Translation: BAD97235.1
CR749463 mRNA Translation: CAH18295.1
CH471062 Genomic DNA Translation: EAW61864.1
CH471062 Genomic DNA Translation: EAW61865.1
BC007829 mRNA Translation: AAH07829.1
BC014253 mRNA Translation: AAH14253.1
BC024737 mRNA Translation: AAH24737.1
AB014733 mRNA Translation: BAB20270.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4279.1 [Q969M3-1]
CCDS64277.1 [Q969M3-2]

NCBI Reference Sequences

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RefSeqi
NP_001020118.1, NM_001024947.3 [Q969M3-1]
NP_001258661.1, NM_001271732.1 [Q969M3-2]
NP_110426.4, NM_030799.8 [Q969M3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000274496; ENSP00000274496; ENSG00000145817 [Q969M3-1]
ENST00000448443; ENSP00000397704; ENSG00000145817 [Q969M3-1]
ENST00000513112; ENSP00000425422; ENSG00000145817 [Q969M3-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
81555

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:81555

UCSC genome browser

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UCSCi
uc003lnk.6 human [Q969M3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF140225 mRNA Translation: AAG48521.1
AY640925 mRNA Translation: AAV51256.1
AY640926 mRNA Translation: AAV51257.1
AY640927 mRNA Translation: AAV51258.1
AY640928 mRNA Translation: AAV51259.1
AY640929 mRNA No translation available.
AY640934 mRNA Translation: AAV51260.1
AY037152 mRNA Translation: AAK67644.1
AY358863 mRNA Translation: AAQ89222.1
AK054576 mRNA Translation: BAB70763.1
AF318329 mRNA Translation: AAL55836.1
AK223515 mRNA Translation: BAD97235.1
CR749463 mRNA Translation: CAH18295.1
CH471062 Genomic DNA Translation: EAW61864.1
CH471062 Genomic DNA Translation: EAW61865.1
BC007829 mRNA Translation: AAH07829.1
BC014253 mRNA Translation: AAH14253.1
BC024737 mRNA Translation: AAH24737.1
AB014733 mRNA Translation: BAB20270.1
CCDSiCCDS4279.1 [Q969M3-1]
CCDS64277.1 [Q969M3-2]
RefSeqiNP_001020118.1, NM_001024947.3 [Q969M3-1]
NP_001258661.1, NM_001271732.1 [Q969M3-2]
NP_110426.4, NM_030799.8 [Q969M3-1]

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123519, 55 interactors
IntActiQ969M3, 61 interactors
MINTiQ969M3
STRINGi9606.ENSP00000274496

PTM databases

iPTMnetiQ969M3
PhosphoSitePlusiQ969M3
SwissPalmiQ969M3

Polymorphism and mutation databases

BioMutaiYIPF5
DMDMi74760683

Proteomic databases

EPDiQ969M3
jPOSTiQ969M3
MassIVEiQ969M3
MaxQBiQ969M3
PaxDbiQ969M3
PeptideAtlasiQ969M3
PRIDEiQ969M3
ProteomicsDBi75792 [Q969M3-1]
75793 [Q969M3-2]
75794 [Q969M3-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
81555

Genome annotation databases

EnsembliENST00000274496; ENSP00000274496; ENSG00000145817 [Q969M3-1]
ENST00000448443; ENSP00000397704; ENSG00000145817 [Q969M3-1]
ENST00000513112; ENSP00000425422; ENSG00000145817 [Q969M3-2]
GeneIDi81555
KEGGihsa:81555
UCSCiuc003lnk.6 human [Q969M3-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
81555
DisGeNETi81555

GeneCards: human genes, protein and diseases

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GeneCardsi
YIPF5
HGNCiHGNC:24877 YIPF5
HPAiHPA042338
HPA073622
MIMi611483 gene
neXtProtiNX_Q969M3
OpenTargetsiENSG00000145817
PharmGKBiPA142670548

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3103 Eukaryota
COG5080 LUCA
GeneTreeiENSGT00940000153168
InParanoidiQ969M3
KOiK20363
OMAiHPLKAAD
OrthoDBi1457080at2759
PhylomeDBiQ969M3
TreeFamiTF313100

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
YIPF5 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
YIPF5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
81555
PharosiQ969M3

Protein Ontology

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PROi
PR:Q969M3

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000145817 Expressed in 222 organ(s), highest expression level in nasal cavity mucosa
ExpressionAtlasiQ969M3 baseline and differential
GenevisibleiQ969M3 HS

Family and domain databases

InterProiView protein in InterPro
IPR006977 Yip1
PfamiView protein in Pfam
PF04893 Yip1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYIPF5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q969M3
Secondary accession number(s): D3DQF5
, Q4VSN6, Q53EX4, Q8NHE5, Q9H338, Q9H3U4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: December 1, 2001
Last modified: October 16, 2019
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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