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Entry version 151 (23 Feb 2022)
Sequence version 1 (01 Feb 1997)
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Protein

Inorganic phosphate transporter 1-4

Gene

PHT1-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-affinity transporter for external inorganic phosphate. Acts as a H+:phosphate symporter in both low- and high-Pi conditions. Confers sensitivity to arsenate.

3 Publications

Miscellaneous

Although related to the sugar transporter family, it does not transport sugars.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPhosphate transport, Symport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inorganic phosphate transporter 1-4
Short name:
AtPht1;4
Alternative name(s):
H(+)/Pi cotransporter
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PHT1-4
Synonyms:PHT4, PT2
Ordered Locus Names:At2g38940
ORF Names:T7F6.11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G38940

The Arabidopsis Information Resource

More...
TAIRi
locus:2064895, AT2G38940

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 70ExtracellularSequence analysisAdd BLAST25
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 99CytoplasmicSequence analysis8
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Topological domaini121 – 131ExtracellularSequence analysisAdd BLAST11
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Topological domaini153 – 161CytoplasmicSequence analysis9
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 211ExtracellularSequence analysisAdd BLAST29
Transmembranei212 – 232HelicalSequence analysisAdd BLAST21
Topological domaini233 – 293CytoplasmicSequence analysisAdd BLAST61
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21
Topological domaini315 – 349ExtracellularSequence analysisAdd BLAST35
Transmembranei350 – 370HelicalSequence analysisAdd BLAST21
Topological domaini371 – 372CytoplasmicSequence analysis2
Transmembranei373 – 393HelicalSequence analysisAdd BLAST21
Topological domaini394 – 403ExtracellularSequence analysis10
Transmembranei404 – 424HelicalSequence analysisAdd BLAST21
Topological domaini425 – 442CytoplasmicSequence analysisAdd BLAST18
Transmembranei443 – 463HelicalSequence analysisAdd BLAST21
Topological domaini464 – 484ExtracellularSequence analysisAdd BLAST21
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21
Topological domaini506 – 534CytoplasmicSequence analysisAdd BLAST29

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000504711 – 534Inorganic phosphate transporter 1-4Add BLAST534

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei524PhosphoserineCombined sources1
Modified residuei528PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96303

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
234664

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96303

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed in roots, in tissues connecting the lateral roots to the primary root. Also present in flowers, in senescing anther filaments and in the abscission zone at the base of siliques. Expressed in hydathodes and axillary buds, and in some senescing leaves. After Pi starvation, localized in all cells of undifferentiated root segments, including root tips and root hairs, and in the epidermis, cortex and stellar regions of mature root segments.5 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

In roots by phosphate starvation. Repressed by the Pi analog phosphite (Phi).6 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96303, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96303, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
3818, 7 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G38940.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96303

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni512 – 534DisorderedSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0252, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001265_46_14_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96303

Identification of Orthologs from Complete Genome Data

More...
OMAi
WFFLDLA

Database of Orthologous Groups

More...
OrthoDBi
762280at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96303

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1250.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR004738, Phos_permease

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083, Sugar_tr, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00887, 2A0109, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850, MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96303-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAREQLQVLN ALDVAKTQWY HFTAIIIAGM GFFTDAYDLF CISLVTKLLG
60 70 80 90 100
RIYYHVEGAQ KPGTLPPNVA AAVNGVAFCG TLAGQLFFGW LGDKLGRKKV
110 120 130 140 150
YGMTLMVMVL CSIASGLSFG HEPKAVMATL CFFRFWLGFG IGGDYPLSAT
160 170 180 190 200
IMSEYANKKT RGAFVSAVFA MQGFGIMAGG IFAIIISSAF EAKFPSPAYA
210 220 230 240 250
DDALGSTIPQ ADLVWRIILM AGAIPAAMTY YSRSKMPETA RYTALVAKDA
260 270 280 290 300
KQAASDMSKV LQVEIEPEQQ KLEEISKEKS KAFGLFSKEF MSRHGLHLLG
310 320 330 340 350
TTSTWFLLDI AFYSQNLFQK DIFSAIGWIP PAQSMNAIQE VFKIARAQTL
360 370 380 390 400
IALCSTVPGY WFTVAFIDVI GRFAIQMMGF FFMTVFMFAL AIPYNHWTHK
410 420 430 440 450
ENRIGFVIMY SLTFFFANFG PNATTFVVPA EIFPARFRST CHGISAASGK
460 470 480 490 500
LGAMVGAFGF LYLAQNPDKD KTDAGYPPGI GVRNSLIVLG VVNFLGILFT
510 520 530
FLVPESKGKS LEEMSGENED NENSNNDSRT VPIV
Length:534
Mass (Da):58,599
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8186DBBBCBC8379E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U62331 mRNA Translation: AAB17266.1
AF022872 Genomic DNA Translation: AAB88291.1
AB016166 Genomic DNA Translation: BAA34398.1
AC005770 Genomic DNA Translation: AAC79607.1
CP002685 Genomic DNA Translation: AEC09615.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C84811

NCBI Reference Sequences

More...
RefSeqi
NP_181428.1, NM_129452.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G38940.1; AT2G38940.1; AT2G38940

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
818479

Gramene; a comparative resource for plants

More...
Gramenei
AT2G38940.1; AT2G38940.1; AT2G38940

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G38940

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62331 mRNA Translation: AAB17266.1
AF022872 Genomic DNA Translation: AAB88291.1
AB016166 Genomic DNA Translation: BAA34398.1
AC005770 Genomic DNA Translation: AAC79607.1
CP002685 Genomic DNA Translation: AEC09615.1
PIRiC84811
RefSeqiNP_181428.1, NM_129452.4

3D structure databases

SMRiQ96303
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi3818, 7 interactors
STRINGi3702.AT2G38940.1

PTM databases

iPTMnetiQ96303

Proteomic databases

PaxDbiQ96303
ProteomicsDBi234664

Genome annotation databases

EnsemblPlantsiAT2G38940.1; AT2G38940.1; AT2G38940
GeneIDi818479
GrameneiAT2G38940.1; AT2G38940.1; AT2G38940
KEGGiath:AT2G38940

Organism-specific databases

AraportiAT2G38940
TAIRilocus:2064895, AT2G38940

Phylogenomic databases

eggNOGiKOG0252, Eukaryota
HOGENOMiCLU_001265_46_14_1
InParanoidiQ96303
OMAiWFFLDLA
OrthoDBi762280at2759
PhylomeDBiQ96303

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q96303

Gene expression databases

ExpressionAtlasiQ96303, baseline and differential
GenevisibleiQ96303, AT

Family and domain databases

Gene3Di1.20.1250.20, 1 hit
InterProiView protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR004738, Phos_permease
PfamiView protein in Pfam
PF00083, Sugar_tr, 1 hit
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00887, 2A0109, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPHT14_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96303
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: February 1, 1997
Last modified: February 23, 2022
This is version 151 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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