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Entry version 134 (02 Dec 2020)
Sequence version 1 (01 Dec 2001)
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Protein

General transcription factor IIH subunit 1

Gene

Tfb1

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-112382, Formation of RNA Pol II elongation complex
R-DME-113418, Formation of the Early Elongation Complex
R-DME-5696395, Formation of Incision Complex in GG-NER
R-DME-5696400, Dual Incision in GG-NER
R-DME-674695, RNA Polymerase II Pre-transcription Events
R-DME-6781823, Formation of TC-NER Pre-Incision Complex
R-DME-6782135, Dual incision in TC-NER
R-DME-6782210, Gap-filling DNA repair synthesis and ligation in TC-NER
R-DME-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-DME-72086, mRNA Capping
R-DME-73772, RNA Polymerase I Promoter Escape
R-DME-73776, RNA Polymerase II Promoter Escape
R-DME-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-DME-75953, RNA Polymerase II Transcription Initiation
R-DME-75955, RNA Polymerase II Transcription Elongation
R-DME-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance
R-DME-77075, RNA Pol II CTD phosphorylation and interaction with CE

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
General transcription factor IIH subunit 1
Alternative name(s):
TFIIH basal transcription factor complex subunit 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tfb1
ORF Names:CG8151
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0033929, Tfb1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001192471 – 585General transcription factor IIH subunit 1Add BLAST585

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q960E8

PRoteomics IDEntifications database

More...
PRIDEi
Q960E8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0033929, Expressed in embryo and 38 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q960E8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q960E8, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
62348, 6 interactors

Database of interacting proteins

More...
DIPi
DIP-21835N

Protein interaction database and analysis system

More...
IntActi
Q960E8, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0086676

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q960E8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini104 – 159BSD 1PROSITE-ProRule annotationAdd BLAST56
Domaini180 – 232BSD 2PROSITE-ProRule annotationAdd BLAST53

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TFB1 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2074, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015066

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_037467_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q960E8

Identification of Orthologs from Complete Genome Data

More...
OMAi
FWATHAK

Database of Orthologous Groups

More...
OrthoDBi
946128at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q960E8

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005607, BSD_dom
IPR011993, PH-like_dom_sf
IPR027079, Tfb1/GTF2H1
IPR013876, TFIIH_BTF_p62_N

The PANTHER Classification System

More...
PANTHERi
PTHR12856, PTHR12856, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03909, BSD, 1 hit
PF08567, PH_TFIIH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00751, BSD, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50858, BSD, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q960E8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTSSEDVLL QMGEVRYKKG DGTLYVMNER VAWMAEHRDT VTVSHRYADI
60 70 80 90 100
KTQKISPEGK PKVQLQVVLH DGNTSTFHFV NRQGQAAMLA DRDKVKELLQ
110 120 130 140 150
QLLPNFKRKV DKDLEDKNRI LVENPNLLQL YKDLVITKVL TSDEFWATHA
160 170 180 190 200
KDHALKKMGR SQEIGVSGAF LADIKPQTDG CNGLKYNLTS DVIHCIFKTY
210 220 230 240 250
PAVKRKHFEN VPAKMSEAEF WTKFFQSHYF HRDRLTAGTK DIFTECGKID
260 270 280 290 300
DQALKAAVQQ GAGDPLLDLK KFEDVPLEEG FGSVAGDRNV VNSGNIVHQN
310 320 330 340 350
MIKRFNQHSI MVLKTCANVT SAPSTMTNGT NNANGPVSQS AYTNGMNGKG
360 370 380 390 400
QATATATKSS SDQVDKDEPQ SKKQRLMEKI HYVDLGDPIL EGDDSANGEK
410 420 430 440 450
AKSKHFELSK VERYLNGPVQ NSMYDNHNDP MSLEEVQYKL VRNSESWLNR
460 470 480 490 500
NVQRTFICSK AAVNALGELS PGGSMMRGFQ EQSAGQLVPN DFQRELRHLY
510 520 530 540 550
LSLSELLKHF WSCFPPTSEE LETKLQRMHE TLQRFKMAKL VPFENRAMHE
560 570 580
LSPLRSSLTQ HLNQLLRTAN SKFATWKERK LRNTR
Length:585
Mass (Da):66,339
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i629BE277BC6AF6C0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K726A0A0B4K726_DROME
Transcription factor B1, isoform D
Tfb1 Dmel\CG8151, Dmp62, l(2)06949, l(2)06950, p62
585Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58253.2
AE013599 Genomic DNA Translation: AAM71001.1
AY052097 mRNA Translation: AAK93521.1

NCBI Reference Sequences

More...
RefSeqi
NP_001246321.1, NM_001259392.2
NP_610957.1, NM_137113.4
NP_725382.1, NM_166048.1
NP_725383.1, NM_166049.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0087548; FBpp0086676; FBgn0033929
FBtr0087549; FBpp0086677; FBgn0033929
FBtr0087550; FBpp0086678; FBgn0033929
FBtr0305616; FBpp0294063; FBgn0033929

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36598

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG8151

UCSC genome browser

More...
UCSCi
CG8151-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58253.2
AE013599 Genomic DNA Translation: AAM71001.1
AY052097 mRNA Translation: AAK93521.1
RefSeqiNP_001246321.1, NM_001259392.2
NP_610957.1, NM_137113.4
NP_725382.1, NM_166048.1
NP_725383.1, NM_166049.1

3D structure databases

SMRiQ960E8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi62348, 6 interactors
DIPiDIP-21835N
IntActiQ960E8, 2 interactors
STRINGi7227.FBpp0086676

Proteomic databases

PaxDbiQ960E8
PRIDEiQ960E8

Genome annotation databases

EnsemblMetazoaiFBtr0087548; FBpp0086676; FBgn0033929
FBtr0087549; FBpp0086677; FBgn0033929
FBtr0087550; FBpp0086678; FBgn0033929
FBtr0305616; FBpp0294063; FBgn0033929
GeneIDi36598
KEGGidme:Dmel_CG8151
UCSCiCG8151-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
36598
FlyBaseiFBgn0033929, Tfb1

Phylogenomic databases

eggNOGiKOG2074, Eukaryota
GeneTreeiENSGT00390000015066
HOGENOMiCLU_037467_0_0_1
InParanoidiQ960E8
OMAiFWATHAK
OrthoDBi946128at2759
PhylomeDBiQ960E8

Enzyme and pathway databases

ReactomeiR-DME-112382, Formation of RNA Pol II elongation complex
R-DME-113418, Formation of the Early Elongation Complex
R-DME-5696395, Formation of Incision Complex in GG-NER
R-DME-5696400, Dual Incision in GG-NER
R-DME-674695, RNA Polymerase II Pre-transcription Events
R-DME-6781823, Formation of TC-NER Pre-Incision Complex
R-DME-6782135, Dual incision in TC-NER
R-DME-6782210, Gap-filling DNA repair synthesis and ligation in TC-NER
R-DME-6796648, TP53 Regulates Transcription of DNA Repair Genes
R-DME-72086, mRNA Capping
R-DME-73772, RNA Polymerase I Promoter Escape
R-DME-73776, RNA Polymerase II Promoter Escape
R-DME-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-DME-75953, RNA Polymerase II Transcription Initiation
R-DME-75955, RNA Polymerase II Transcription Elongation
R-DME-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance
R-DME-77075, RNA Pol II CTD phosphorylation and interaction with CE

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
36598, 1 hit in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tfb1, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
36598

Protein Ontology

More...
PROi
PR:Q960E8

Gene expression databases

BgeeiFBgn0033929, Expressed in embryo and 38 other tissues
ExpressionAtlasiQ960E8, baseline and differential
GenevisibleiQ960E8, DM

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR005607, BSD_dom
IPR011993, PH-like_dom_sf
IPR027079, Tfb1/GTF2H1
IPR013876, TFIIH_BTF_p62_N
PANTHERiPTHR12856, PTHR12856, 1 hit
PfamiView protein in Pfam
PF03909, BSD, 1 hit
PF08567, PH_TFIIH, 1 hit
SMARTiView protein in SMART
SM00751, BSD, 2 hits
PROSITEiView protein in PROSITE
PS50858, BSD, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTF2H1_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q960E8
Secondary accession number(s): A4UZH0, Q0E978
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 9, 2003
Last sequence update: December 1, 2001
Last modified: December 2, 2020
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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