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Protein

Spore wall protein 2

Gene

SWP2

Organism
Encephalitozoon intestinalis (Microsporidian parasite)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Spore wall component.

Miscellaneous

SWP2 is a major antigen recognized during host infection.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSporulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Spore wall protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SWP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEncephalitozoon intestinalis (Microsporidian parasite)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri58839 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiFungi incertae sedisMicrosporidiaUnikaryonidaeEncephalitozoon

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18Sequence analysisAdd BLAST18
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500006023919 – 1002Spore wall protein 2Add BLAST984

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi308N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q95WA4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Synthesized in the fully form of sporont.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a complex composed of at least SWP1 and SWP2.1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q95WA4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati357 – 3681Add BLAST12
Repeati369 – 3802Add BLAST12
Repeati381 – 3923Add BLAST12
Repeati393 – 4044Add BLAST12
Repeati405 – 4165Add BLAST12
Repeati417 – 4286Add BLAST12
Repeati429 – 4407Add BLAST12
Repeati441 – 4528Add BLAST12
Repeati453 – 4649Add BLAST12
Repeati465 – 47610Add BLAST12
Repeati477 – 48811Add BLAST12
Repeati489 – 50012Add BLAST12
Repeati501 – 51213Add BLAST12
Repeati513 – 52414Add BLAST12
Repeati525 – 53615Add BLAST12
Repeati537 – 54816Add BLAST12
Repeati549 – 56017Add BLAST12
Repeati561 – 57218Add BLAST12
Repeati576 – 58719Add BLAST12
Repeati588 – 59920Add BLAST12
Repeati600 – 61121Add BLAST12
Repeati615 – 62622Add BLAST12
Repeati627 – 63823Add BLAST12
Repeati639 – 65024Add BLAST12
Repeati651 – 66225; degenerateAdd BLAST12
Repeati663 – 67426; degenerateAdd BLAST12
Repeati678 – 68927Add BLAST12
Repeati693 – 70428Add BLAST12
Repeati708 – 71929Add BLAST12
Repeati723 – 73430Add BLAST12
Repeati735 – 74631Add BLAST12
Repeati747 – 75832Add BLAST12
Repeati759 – 77033Add BLAST12
Repeati774 – 78534Add BLAST12
Repeati786 – 79735Add BLAST12
Repeati801 – 81236Add BLAST12
Repeati816 – 82737Add BLAST12
Repeati831 – 84238Add BLAST12
Repeati843 – 85439Add BLAST12
Repeati855 – 86640Add BLAST12
Repeati867 – 87841Add BLAST12
Repeati882 – 89342Add BLAST12
Repeati894 – 90543Add BLAST12
Repeati906 – 9154410
Repeati918 – 92945Add BLAST12
Repeati930 – 94146Add BLAST12
Repeati942 – 95347Add BLAST12
Repeati957 – 96948Add BLAST13
Repeati972 – 98349; degenerateAdd BLAST12
Repeati987 – 99850; degenerateAdd BLAST12

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni357 – 99850 X 12 AA tandem repeats of E-E-G-E-D-K-D-N-T-G-E-GAdd BLAST642

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi61 – 105Ser-richAdd BLAST45
Compositional biasi354 – 1000Glu/Gly-richAdd BLAST647

Keywords - Domaini

Repeat, Signal

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q95WA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKLSLLLSL ASFTAVLANQ RPRCQRCPVS SSKYFQQNNL LESRFQNEVQ
60 70 80 90 100
RLCARRVREE SSSESSSSSS SEDCSRRRRR PHREWEDSCS SSYSSCSSTD
110 120 130 140 150
SCSSSAPCPP PVAQRCDIEL KTPIILMGER IYEFLKNYED QYKKAVLLFL
160 170 180 190 200
TNILSQISGF NPVFPGGDYD ALIEQLKTLG VTVPANTAAE LAAIDAAESS
210 220 230 240 250
ALTRAIQANA QKVISDLLTR VSAMCYLDIM SLVNSGLLAS QVSSVFNNIQ
260 270 280 290 300
PIITIAGNDL FAKQMAVFQK LSKTLISTAV TNALQGNRAK FTRFYTTQTS
310 320 330 340 350
NLQTSVQNSS KTLTSELKKL ATDTETAFTA FANAEISTPV RRIFRRSITS
360 370 380 390 400
SGFEDAEEGE DKDNTGEGEE GEDKDNTGEG EEGEDKDNTG EGEEGEDKDN
410 420 430 440 450
TGEGEEGEDK DNTGEGEEGE DKDNTGEGEE GEDKDNTGEG EEGEDKDNTG
460 470 480 490 500
EGEEGEDKDN TGEGEEGEDK DNTGEGEEGE DKDNTGEGEE GEDKDNTGEG
510 520 530 540 550
EEGEDKDNTG EGEEGEDKDN TGEGEEGEDK DNTGEGEEGE DKDNTGEGEE
560 570 580 590 600
GEDKDNTGEG EEGEDKDNTG EGEEGEEGED KDNTGEGEEG EDKDNTGEGE
610 620 630 640 650
EGEDKDNTGE GEEGEEGEDK DNTGEGEEGE DKDNTGEGEE GEDKDNTGEG
660 670 680 690 700
EEGEDKDNTG DAEEGEEGED KDSTGEGEEG EDKDNTGEGE EGEEGEDKDN
710 720 730 740 750
TGEGEEGEEG EDKDNTGEGE EGEEGEDKDN TGEGEEGEDK DNTGEGEEGE
760 770 780 790 800
DKDNTGEGDE GEDKDNTGEG EEGEEGEDKD NTGEGEEGED KDNTGEGEEG
810 820 830 840 850
EEGEDKDNTG EGEEGEEGED KDNTGEGEEG EEGEDKDNTG EGEEGEDKDN
860 870 880 890 900
TGEGEEGEDK DNTGEGEEGE DKDNTGEGEE GEEGEDKDNT GEGEEGEDKD
910 920 930 940 950
NTGEGEEGED KDNTGEGEEG EDKDNTGEGE EGEDKDNTGE GEEGEDKDNT
960 970 980 990 1000
GEGEEGEEGE DKDNTGDAEE GEEGEDKDNT GDAEEGEEGE DKDNTEEGEE

TT
Length:1,002
Mass (Da):107,177
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3AE8E3BD8531D73D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF355749 Genomic DNA Translation: AAL27282.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF355749 Genomic DNA Translation: AAL27282.1

3D structure databases

SMRiQ95WA4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ95WA4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSWP2_ENCIN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q95WA4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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