UniProtKB - Q95VY4 (Q95VY4_AEDAE)
Protein
Cysteine-S-conjugate beta-lyase 2
Gene
KAT
Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Functioni
Catalytic activityi
GO - Molecular functioni
- cysteine-S-conjugate beta-lyase activity Source: UniProtKB-EC
- kynurenine-glyoxylate transaminase activity Source: UniProtKB-EC
- kynurenine-oxoglutarate transaminase activity Source: UniProtKB-EC
- pyridoxal phosphate binding Source: InterPro
GO - Biological processi
- biosynthetic process Source: InterPro
Keywordsi
Molecular function | AminotransferaseImported, Transferase |
Enzyme and pathway databases
BRENDAi | 2.6.1.7, 149 |
SABIO-RKi | Q95VY4 |
Names & Taxonomyi
Protein namesi | Recommended name: Cysteine-S-conjugate beta-lyase 2ARBA annotation (EC:2.6.1.63ARBA annotation, EC:2.6.1.7ARBA annotation, EC:4.4.1.13ARBA annotation)Alternative name(s): Kynurenine aminotransferase 3ARBA annotation Kynurenine aminotransferase IIIARBA annotation Kynurenine--glyoxylate transaminaseARBA annotation Kynurenine--oxoglutarate transaminase 3ARBA annotation Kynurenine--oxoglutarate transaminase IIIARBA annotation |
Gene namesi | Name:KATImported |
Organismi | Aedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported |
Taxonomic identifieri | 7159 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia |
Interactioni
Subunit structurei
Homodimer.
ARBA annotationStructurei
3D structure databases
SMRi | Q95VY4 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q95VY4 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 87 – 469 | Aminotran_1_2InterPro annotationAdd BLAST | 383 |
Phylogenomic databases
HOGENOMi | CLU_017584_4_0_1 |
Family and domain databases
Gene3Di | 3.40.640.10, 1 hit 3.90.1150.10, 1 hit |
InterProi | View protein in InterPro IPR004839, Aminotransferase_I/II IPR034612, KAT_III IPR015424, PyrdxlP-dep_Trfase IPR015422, PyrdxlP-dep_Trfase_dom1 IPR015421, PyrdxlP-dep_Trfase_major |
PANTHERi | PTHR43807:SF6, PTHR43807:SF6, 1 hit |
Pfami | View protein in Pfam PF00155, Aminotran_1_2, 1 hit |
SUPFAMi | SSF53383, SSF53383, 1 hit |
i Sequence
Sequence statusi: Complete.
Q95VY4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMFLRNHNSV GGAIRTAVVL QDLQFIVSNK SSALTGAVSS VHRQQIRTMS
60 70 80 90 100
STSNETMHNK FDLPKRYQGS TKSVWVEYIQ LAAQYKPLNL GQGFPDYHAP
110 120 130 140 150
KYALNALAAA ANSPDPLANQ YTRGFGHPRL VQALSKLYSQ LVDRTINPMT
160 170 180 190 200
EVLVTVGAYE ALYATIQGHV DEGDEVIIIE PFFDCYEPMV KAAGGIPRFI
210 220 230 240 250
PLKPNKTGGT ISSADWVLDN NELEALFNEK TKMIIINTPH NPLGKVMDRA
260 270 280 290 300
ELEVVANLCK KWNVLCVSDE VYEHMVFEPF EHIRICTLPG MWERTITIGS
310 320 330 340 350
AGKTFSLTGW KIGWAYGPEA LLKNLQMVHQ NCVYTCATPI QEAIAVGFET
360 370 380 390 400
ELKRLKSPEC YFNSISGELM AKRDYMASFL AEVGMNPTVP QGGYFMVADW
410 420 430 440 450
SSLDSKVDLT QETDARKDYR FTKWMTKSVG LQGIPPSAFY SEPNKHLGED
460 470
FVRYCFFKKD ENLQKAAEIL RKWKGSS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF395204 mRNA Translation: AAK97625.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF395204 mRNA Translation: AAK97625.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1YIY | X-ray | 1.90 | A/B | 49-477 | [»] | |
1YIZ | X-ray | 1.55 | A/B | 49-477 | [»] | |
2R5C | X-ray | 1.96 | A/B | 49-477 | [»] | |
2R5E | X-ray | 1.84 | A/B | 49-477 | [»] | |
5VEH | X-ray | 1.55 | A/B | 49-475 | [»] | |
SMRi | Q95VY4 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Phylogenomic databases
HOGENOMi | CLU_017584_4_0_1 |
Enzyme and pathway databases
BRENDAi | 2.6.1.7, 149 |
SABIO-RKi | Q95VY4 |
Miscellaneous databases
EvolutionaryTracei | Q95VY4 |
Family and domain databases
Gene3Di | 3.40.640.10, 1 hit 3.90.1150.10, 1 hit |
InterProi | View protein in InterPro IPR004839, Aminotransferase_I/II IPR034612, KAT_III IPR015424, PyrdxlP-dep_Trfase IPR015422, PyrdxlP-dep_Trfase_dom1 IPR015421, PyrdxlP-dep_Trfase_major |
PANTHERi | PTHR43807:SF6, PTHR43807:SF6, 1 hit |
Pfami | View protein in Pfam PF00155, Aminotran_1_2, 1 hit |
SUPFAMi | SSF53383, SSF53383, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q95VY4_AEDAE | |
Accessioni | Q95VY4Primary (citable) accession number: Q95VY4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 1, 2001 |
Last sequence update: | December 1, 2001 | |
Last modified: | October 7, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |