UniProtKB - Q95VY4 (Q95VY4_AEDAE)

BLAST

>tr|Q95VY4|Q95VY4_AEDAE Kynurenine aminotransferase OS=Aedes aegypti OX=7159 GN=KAT PE=1 SV=1
MMFLRNHNSVGGAIRTAVVLQDLQFIVSNKSSALTGAVSSVHRQQIRTMSSTSNETMHNK
FDLPKRYQGSTKSVWVEYIQLAAQYKPLNLGQGFPDYHAPKYALNALAAAANSPDPLANQ
YTRGFGHPRLVQALSKLYSQLVDRTINPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIE
PFFDCYEPMVKAAGGIPRFIPLKPNKTGGTISSADWVLDNNELEALFNEKTKMIIINTPH
NPLGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGS
AGKTFSLTGWKIGWAYGPEALLKNLQMVHQNCVYTCATPIQEAIAVGFETELKRLKSPEC
YFNSISGELMAKRDYMASFLAEVGMNPTVPQGGYFMVADWSSLDSKVDLTQETDARKDYR
FTKWMTKSVGLQGIPPSAFYSEPNKHLGEDFVRYCFFKKDENLQKAAEILRKWKGSS

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History
Entry version 90 (10 Oct 2018)
Sequence version 1 (01 Dec 2001)
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Protein

Submitted name:

Kynurenine aminotransferase

Gene

KAT

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

pyridoxal phosphate binding Source: InterPro
transaminase activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

biosynthetic process Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	AminotransferaseImported, Transferase

Molecular function

AminotransferaseImported, Transferase

Enzyme and pathway databases

BRENDAⁱ	2.6.1.7 149
SABIO-RKⁱ	Q95VY4

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Kynurenine aminotransferaseImported
Gene namesⁱ	Name:KATImported
Organismⁱ	Aedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifierⁱ	7159 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Culicomorpha › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q95VY4
SMRⁱ	Q95VY4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q95VY4

EvolutionaryTraceⁱ

Q95VY4

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	87 – 469	Aminotran_1_2InterPro annotationAdd BLAST		383

Phylogenomic databases

eggNOGⁱ	KOG0257 Eukaryota COG0436 LUCA

eggNOGⁱ

KOG0257 Eukaryota
COG0436 LUCA

Family and domain databases

Gene3Dⁱ	3.40.640.10, 1 hit 3.90.1150.10, 2 hits
InterProⁱ	View protein in InterPro IPR004839 Aminotransferase_I/II IPR015424 PyrdxlP-dep_Trfase IPR015422 PyrdxlP-dep_Trfase_dom1 IPR015421 PyrdxlP-dep_Trfase_major
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00155 Aminotran_1_2, 1 hit
SUPFAMⁱ	SSF53383 SSF53383, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q95VY4-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MMFLRNHNSV GGAIRTAVVL QDLQFIVSNK SSALTGAVSS VHRQQIRTMS 
        60         70         80         90        100
STSNETMHNK FDLPKRYQGS TKSVWVEYIQ LAAQYKPLNL GQGFPDYHAP 
       110        120        130        140        150
KYALNALAAA ANSPDPLANQ YTRGFGHPRL VQALSKLYSQ LVDRTINPMT 
       160        170        180        190        200
EVLVTVGAYE ALYATIQGHV DEGDEVIIIE PFFDCYEPMV KAAGGIPRFI 
       210        220        230        240        250
PLKPNKTGGT ISSADWVLDN NELEALFNEK TKMIIINTPH NPLGKVMDRA 
       260        270        280        290        300
ELEVVANLCK KWNVLCVSDE VYEHMVFEPF EHIRICTLPG MWERTITIGS 
       310        320        330        340        350
AGKTFSLTGW KIGWAYGPEA LLKNLQMVHQ NCVYTCATPI QEAIAVGFET 
       360        370        380        390        400
ELKRLKSPEC YFNSISGELM AKRDYMASFL AEVGMNPTVP QGGYFMVADW 
       410        420        430        440        450
SSLDSKVDLT QETDARKDYR FTKWMTKSVG LQGIPPSAFY SEPNKHLGED 
       460        470 
FVRYCFFKKD ENLQKAAEIL RKWKGSS

Length:477

Mass (Da):53,505

Last modified:December 1, 2001 - v1

Checksum:ⁱD71BFC22649D6D11

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF395204 mRNA Translation: AAK97625.1
UniGeneⁱ	Aae.17431

Protein	Similar proteins		Species	Score	Length	Source
Q95VY4	Putative kynurenine aminotransferase glutamine transaminase k		AEDAL		484	UniRef90_Q95VY4
AAEL004435-PA		AEDAE		477
Putative kynurenine aminotransferase glutamine transaminase k (Fragment)		AEDAL		482
Uncharacterized protein		AEDAL		429
UPI000C21032E		AEDAE		427
+3

Protein	Similar proteins		Species	Score	Length	Source
Q95VY4	Kynurenine/oxoglutarate transaminase 1, putative		PEDHC		467	UniRef50_E0VHR9
Kynurenine--oxoglutarate transaminase 3		ACREC		410
Kynurenine--oxoglutarate transaminase 3		CRAGI		477
Putative kynurenine aminotransferase glutamine transaminase k		Nyssomyia neivai		457
Uncharacterized protein		TETUR		335
+328

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF395204 mRNA Translation: AAK97625.1
UniGeneⁱ	Aae.17431

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1YIY	X-ray	1.90	A/B	49-477	[»]
	1YIZ	X-ray	1.55	A/B	49-477	[»]
	2R5C	X-ray	1.96	A/B	49-477	[»]
	2R5E	X-ray	1.84	A/B	49-477	[»]
	5VEH	X-ray	1.55	A/B	49-475	[»]
ProteinModelPortalⁱ	Q95VY4
SMRⁱ	Q95VY4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

eggNOGⁱ	KOG0257 Eukaryota COG0436 LUCA

eggNOGⁱ

KOG0257 Eukaryota
COG0436 LUCA

Enzyme and pathway databases

BRENDAⁱ	2.6.1.7 149
SABIO-RKⁱ	Q95VY4

Miscellaneous databases

EvolutionaryTraceⁱ	Q95VY4

EvolutionaryTraceⁱ

Q95VY4

Family and domain databases

Gene3Dⁱ	3.40.640.10, 1 hit 3.90.1150.10, 2 hits
InterProⁱ	View protein in InterPro IPR004839 Aminotransferase_I/II IPR015424 PyrdxlP-dep_Trfase IPR015422 PyrdxlP-dep_Trfase_dom1 IPR015421 PyrdxlP-dep_Trfase_major
Pfamⁱ	View protein in Pfam PF00155 Aminotran_1_2, 1 hit
SUPFAMⁱ	SSF53383 SSF53383, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q95VY4_AEDAE
Accessionⁱ	Q95VY4Primary (citable) accession number: Q95VY4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 1, 2001
	Last sequence update:	December 1, 2001
	Last modified:	October 10, 2018
	This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources

UniProtKB - Q95VY4 (Q95VY4_AEDAE)

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Kynurenine aminotransferase

KAT

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Structureⁱ

3D structure databases

Miscellaneous databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniRef

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Annotation systems

Supporting data

UniProtKB - Q95VY4 (Q95VY4_AEDAE)

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Kynurenine aminotransferase

KAT

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ