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Protein

Beta-galactosidase-1-like protein

Gene

GLB1L

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable glycosyl hydrolase.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei186Proton donorSequence analysis1
Active sitei264NucleophileSequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase

Protein family/group databases

CAZyiGH35 Glycoside Hydrolase Family 35

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase-1-like protein (EC:3.2.1.-)
Gene namesi
Name:GLB1L
ORF Names:QtsA-15875, QtsA-16327, QtsA-17830
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000031360528 – 654Beta-galactosidase-1-like proteinAdd BLAST627

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi97N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi243N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ95LV1

Structurei

3D structure databases

ProteinModelPortaliQ95LV1
SMRiQ95LV1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 35 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00390000006586
HOVERGENiHBG004841

Family and domain databases

Gene3Di2.60.120.260, 3 hits
InterProiView protein in InterPro
IPR026283 B-gal_1-like
IPR008979 Galactose-bd-like_sf
IPR031330 Gly_Hdrlase_35_cat
IPR001944 Glycoside_Hdrlase_35
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR23421 PTHR23421, 1 hit
PfamiView protein in Pfam
PF01301 Glyco_hydro_35, 1 hit
PIRSFiPIRSF006336 B-gal, 1 hit
PRINTSiPR00742 GLHYDRLASE35
SUPFAMiSSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q95LV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPKKPSCLR SLLLPLSLTL LLPQADTRSF IVDRDHDRFL LDGAPFRYVS
60 70 80 90 100
GSLHYFRVPR VLWADRLLKM RWSGLNAIQF YVPWNYHEPQ PGVYNFNGSR
110 120 130 140 150
DLIAFLNEAA LANLLVILRP GPYICAEWEM GGLPSWLLRK PEIRLRTSDP
160 170 180 190 200
DFLAAVDSWF KVLLPKIYPW LYHNGGNIIS IQVENEYGSY GACDFSYMRH
210 220 230 240 250
LAGLFRALLG EKILLFTTDG PEGLKCGSLQ GLYTTVDFGP ADNMTKIFTL
260 270 280 290 300
LRKYEPHGPL VNSEYYTGWL DYWGQNHSTR SVSAVTKGLE NMLKLGASVN
310 320 330 340 350
MYMFHGGTNF GYWNGADKKG RFLSITTSYD YDAPISEAGD PTPKLFALRD
360 370 380 390 400
VISKFQEVPL GPLPPPSPKM MVGPLTLHLV GHLLAFLDLL CPSGPIRSIL
410 420 430 440 450
PMTFEAVKQD RGFMLYRTYM THTIFEPTPF WVPNNGVHDR AYVMVDGVFQ
460 470 480 490 500
GVLERNMRDK LFLMGKVGSK LDILVENMGR LSFGSNSSDF KGLLEPPILG
510 520 530 540 550
QTILTQWMMF PLKIDNLVKW WFLLQLPKWP YPQAPSGPTF YSKTFPILGS
560 570 580 590 600
VGDTFLHLPG WTKGQVWING FNLGRYWTKR GPQQTLYVPR FLLFPRGALN
610 620 630 640 650
KITLLELENV PLQPQVQFLD KPILNSTSTL HRTHINSLSA DTLSASEPME

LSGH
Length:654
Mass (Da):74,113
Last modified:December 1, 2001 - v1
Checksum:iE0815FB08856919E
GO

Sequence cautioni

The sequence BAE01075 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33D → N in BAB64453 (PubMed:12498619).Curated1
Sequence conflicti627T → A in BAB64453 (PubMed:12498619).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB071060 mRNA Translation: BAB64453.1
AB071090 mRNA Translation: BAB64484.1
AB168978 mRNA Translation: BAE01075.1 Different initiation.
RefSeqiNP_001271478.1, NM_001284549.1
XP_005574408.1, XM_005574351.2
XP_015287616.1, XM_015432130.1
UniGeneiMfa.6590

Genome annotation databases

EnsembliENSMFAT00000009100; ENSMFAP00000034869; ENSMFAG00000003895
GeneIDi102141964
KEGGimcf:102141964

Similar proteinsi

Entry informationi

Entry nameiGLB1L_MACFA
AccessioniPrimary (citable) accession number: Q95LV1
Secondary accession number(s): Q4R748, Q95LY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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