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UniProtKB - Q95KB4 (S35B4_MACFA)
Protein
UDP-xylose and UDP-N-acetylglucosamine transporter
Gene
SLC35B4
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Functioni
Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
By similarityGO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
- transmembrane transport Source: InterPro
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: UDP-xylose and UDP-N-acetylglucosamine transporterAlternative name(s): Solute carrier family 35 member B4 |
Gene namesi | Name:SLC35B4 ORF Names:QccE-22467, QmoA-11096 |
Organismi | Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) |
Taxonomic identifieri | 9541 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Proteomesi |
|
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 4 – 24 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 30 – 50 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 59 – 79 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 92 – 112 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 117 – 137 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 153 – 173 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 201 – 221 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 229 – 249 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 251 – 267 | HelicalSequence analysisAdd BLAST | 17 | |
Transmembranei | 268 – 288 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 291 – 311 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213386 | 1 – 331 | UDP-xylose and UDP-N-acetylglucosamine transporterAdd BLAST | 331 |
Structurei
3D structure databases
AlphaFoldDBi | Q95KB4 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1583, Eukaryota |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q95KB4-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MRPALAVGLV FAGCCSNVIF LELLARKHPG CGNIVTFAQF LFIAVEGFLF
60 70 80 90 100
EADLGRKPPA IPIRYYAIMV TMFFTVSVVN NYALNLNIAM PLHMIFRSGS
110 120 130 140 150
LIANMILGII ILKKRYSIFK YTSIALVSVG IFICTFMSAK QVTSQSSLSE
160 170 180 190 200
NDGFQAFVWW LLGIGALTFA LLMSARMGIF QETLYKQFGK HSKEALFYNH
210 220 230 240 250
ALPLPGFIFL ASDIYDHAVL FNKSELYEIP GIGVTLPIMW FYLLMNIITQ
260 270 280 290 300
YVCIRGVFIL TTECASLTVT LVVTLRKFVS LIFSILYFQN PFTLWHWLGT
310 320 330
LFVFIGTLMY TEVWNNLGTT KSEPQKDNKK N
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 80 | N → D in BAB41143 (Ref. 1) Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_016201 | 103 – 166 | ANMIL…LGIGA → HPHHGVRLPHRHARRDPTQI CEPHLFHLVLPEPLHPVALA GHPVCLHWDLNVHRGVEQPR DHKK in isoform 2. 1 PublicationAdd BLAST | 64 | |
Alternative sequenceiVSP_016202 | 167 – 331 | Missing in isoform 2. 1 PublicationAdd BLAST | 165 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB060201 mRNA Translation: BAB41143.1 AB063006 mRNA Translation: BAB60758.1 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB060201 mRNA Translation: BAB41143.1 AB063006 mRNA Translation: BAB60758.1 |
3D structure databases
AlphaFoldDBi | Q95KB4 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9541.XP_005550871.1 |
Phylogenomic databases
eggNOGi | KOG1583, Eukaryota |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S35B4_MACFA | |
Accessioni | Q95KB4Primary (citable) accession number: Q95KB4 Secondary accession number(s): Q9BE34 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families