Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q95168 (ZO2_CANLF)

Entry version 148 (02 Jun 2021)
Sequence version 1 (01 Feb 1997)
Previous versions | rss
Add a publicationFeedback
Protein

Tight junction protein ZO-2

Gene

TJP2

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in tight junctions and adherens junctions.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tight junction protein ZO-2
Alternative name(s):
Tight junction protein 2
Zona occludens protein 2
Zonula occludens protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TJP2
Synonyms:ZO2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCanis lupus familiaris (Dog) (Canis familiaris)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9615 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Canidae › Canis ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002254 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Nucleus, Tight junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000945421 – 1174Tight junction protein ZO-2Add BLAST1174

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei107PhosphoserineBy similarity1
Modified residuei127PhosphoserineBy similarity1
Modified residuei130PhosphoserineBy similarity1
Modified residuei140PhosphoserineBy similarity1
Modified residuei145PhosphoserineBy similarity1
Modified residuei147PhosphoserineBy similarity1
Modified residuei151PhosphoserineBy similarity1
Modified residuei173PhosphoserineBy similarity1
Modified residuei195PhosphoserineBy similarity1
Modified residuei217PhosphoserineBy similarity1
Modified residuei239PhosphoserineBy similarity1
Modified residuei309PhosphoserineBy similarity1
Modified residuei382PhosphoserineBy similarity1
Modified residuei384PhosphoserineBy similarity1
Modified residuei390PhosphoserineBy similarity1
Modified residuei399PhosphoserineBy similarity1
Modified residuei408PhosphoserineBy similarity1
Modified residuei414PhosphoserineBy similarity1
Modified residuei415PhosphoserineBy similarity1
Modified residuei439PhosphothreonineBy similarity1
Modified residuei483PhosphoserineBy similarity1
Modified residuei558PhosphotyrosineBy similarity1
Modified residuei686PhosphoserineBy similarity1
Modified residuei886PhosphoserineBy similarity1
Modified residuei889PhosphothreonineBy similarity1
Modified residuei897PhosphoserineBy similarity1
Modified residuei904PhosphoserineBy similarity1
Modified residuei909PhosphothreonineBy similarity1
Modified residuei917PhosphothreonineBy similarity1
Modified residuei950PhosphoserineBy similarity1
Modified residuei962PhosphoserineBy similarity1
Modified residuei970PhosphoserineBy similarity1
Modified residuei990PhosphoserineBy similarity1
Modified residuei1052PhosphoserineBy similarity1
Modified residuei1102PhosphotyrosineBy similarity1
Modified residuei1131PhosphoserineBy similarity1
Modified residuei1143PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q95168

PRoteomics IDEntifications database

More...PRIDEi		Q95168

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q95168

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer, and heterodimer with ZO1 and UBN1.

Interacts with SCRIB (By similarity).

Interacts with occludin and SAFB. Interaction with SAFB occurs in the nucleus.

Interacts with USP53 (via the C-terminal region) (By similarity).

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		139773, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q95168, 2 interactors

Molecular INTeraction database

More...MINTi		Q95168

STRING: functional protein association networks

More...STRINGi		9612.ENSCAFP00000002794

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q95168

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 97PDZ 1PROSITE-ProRule annotationAdd BLAST88
Domaini291 – 369PDZ 2PROSITE-ProRule annotationAdd BLAST79
Domaini493 – 574PDZ 3PROSITE-ProRule annotationAdd BLAST82
Domaini588 – 653SH3PROSITE-ProRule annotationAdd BLAST66
Domaini679 – 860Guanylate kinase-likePROSITE-ProRule annotationAdd BLAST182

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni125 – 290DisorderedSequence analysisAdd BLAST166
Regioni391 – 430DisorderedSequence analysisAdd BLAST40
Regioni456 – 490DisorderedSequence analysisAdd BLAST35
Regioni904 – 1065DisorderedSequence analysisAdd BLAST162
Regioni1100 – 1174DisorderedSequence analysisAdd BLAST75
Regioni1172 – 1174Interaction with SCRIBBy similarity3

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi125 – 284Basic and acidic residuesSequence analysisAdd BLAST160
Compositional biasi391 – 429Basic and acidic residuesSequence analysisAdd BLAST39
Compositional biasi911 – 925Acidic residuesSequence analysisAdd BLAST15
Compositional biasi940 – 965Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi981 – 996Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi997 – 1016Polar residuesSequence analysisAdd BLAST20
Compositional biasi1141 – 1156Basic and acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MAGUK family.Curated

Keywords - Domaini

Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3580, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q95168

Database of Orthologous Groups

More...OrthoDBi		1175136at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd12027, SH3_ZO-2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.30.42.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008145, GK/Ca_channel_bsu
IPR008144, Guanylate_kin-like_dom
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR005417, ZO
IPR005419, ZO-2
IPR035598, ZO-2_SH3

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00625, Guanylate_kin, 1 hit
PF00595, PDZ, 3 hits
PF07653, SH3_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01597, ZONOCCLUDNS
PR01599, ZONOCCLUDNS2

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00072, GuKc, 1 hit
SM00228, PDZ, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50044, SSF50044, 1 hit
SSF50156, SSF50156, 3 hits
SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50052, GUANYLATE_KINASE_2, 1 hit
PS50106, PDZ, 3 hits
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q95168-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEELIWEQYT VTLQKDSKRG FGIAVSGGRD NPHFENGETS IVISDVLPGG 
        60         70         80         90        100
PADGLLQEND RVVMVNGTPM EDVLHSFAVQ QLRKSGKIAA IVVKRPRKVQ 
       110        120        130        140        150
LAPPQGSLPV DEDDRAFEVM DEFDGRSARS GYSERSRRSS HGGRSRSWED 
       160        170        180        190        200
SPERGRPHER AWSQERERSR GRSLERGLDH DDDYRRPRER SRGRSLERGL 
       210        220        230        240        250
DHDDDYGRPG ERSHGMSTDR GYDRGYDRGY DRGYDRTYSP EAEYGRRTQP 
       260        270        280        290        300
DARHAGSRSR SREHLRSRSP SPELRGRPDH AGQPDSDRPI GVLLMKSKAN 
       310        320        330        340        350
EEYGLRLGSQ IFIKQMTRTA LATKDGNLHE GDIILKINGT VTENMSLTDA 
       360        370        380        390        400
RKLIEKSRGK LQLVVLRDSK QTLINIPSLN DSDSEIEDIS EIESNRSFSP 
       410        420        430        440        450
EERRQQYSDY DYHSSNEKLK ERPNSREDMQ NRWSRMGATP TPFKSMGDIA 
       460        470        480        490        500
SVVGTENSKE PRYQEEPPAP QPKAAPRTFL RPSPEDEAIY GPNTKMVRFK 
       510        520        530        540        550
KGDSVGLRLA GGNDVGIFVA GIQEGTSAEQ EGLQEGDQIL KVNTQDFRGL 
       560        570        580        590        600
VREDAVLYLL EIPKGEMVTI LAQSRADVYR DILACGRGDS FFIRSHFECE 
       610        620        630        640        650
KETPQSLAFS RGEVFRVVDT LYDGKLGHWL AVRIGNELEK GLIPNKSRAE 
       660        670        680        690        700
QMASVQNAQR DNAGDRADFW RMRGQRSGMK KNLRKSREDL TAAVSVSTKF 
       710        720        730        740        750
PAYERVLLRE AGFKRPVVLF GPIADIALEK LANELPDLFQ TAKTEPKDAG 
       760        770        780        790        800
SEKSSGVVRL NTVRQIIEQD KHALLDVTPK AVDLLNYTQW FPIVIFFNPD 
       810        820        830        840        850
SRQGVKTMRQ RLNPTSNKSS RKLYDQANKL KKTCAHLFTA TINLNSANDS 
       860        870        880        890        900
WFGSLKDTIQ HQQGEAVWVS EGKMEGMDDD PEDRMSYLTA MGADYLSCDS 
       910        920        930        940        950
RLISDFEDTD GEGGAYTDNE LDEPAEEPLV SSITRSSEPV QHEESIRKPS 
       960        970        980        990       1000
PEPRAQMRRA ASRDQLRDSS PPPAFKPEPP KAKTQNREES FDISRSHDYK 
      1010       1020       1030       1040       1050
SNPSAVAGNE VSGASTRSCP PPIAAKPSFG RSILKPSTPV PSPESEEVGE 
      1060       1070       1080       1090       1100
GSEEQEGAPK SVLGKVKIFE KMDHKARLQR MQELQEAQNA RIEIAQKHPD 
      1110       1120       1130       1140       1150
IYAVPIKTHK PDPGLSQHTS SRPPEPQKGP SRLYQDPRGS YGSDAEEEEY 
      1160       1170 
RQQLSEHSKR GYYSQPSRYR DTEL
Length:1,174
Mass (Da):132,086
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i45AB836BBDDB1226
GO
Isoform 2 (identifier: Q95168-2)
Sequence is not available
Length:–
Mass (Da):–

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L27152 mRNA Translation: AAC37332.1

NCBI Reference Sequences

More...RefSeqi		NP_001003204.1, NM_001003204.1 [Q95168-1]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		403854

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		cfa:403854

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27152 mRNA Translation: AAC37332.1
RefSeqiNP_001003204.1, NM_001003204.1 [Q95168-1]

3D structure databases

SMRiQ95168
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi139773, 1 interactor
IntActiQ95168, 2 interactors
MINTiQ95168
STRINGi9612.ENSCAFP00000002794

PTM databases

iPTMnetiQ95168

Proteomic databases

PaxDbiQ95168
PRIDEiQ95168

Genome annotation databases

GeneIDi403854
KEGGicfa:403854

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9414

Phylogenomic databases

eggNOGiKOG3580, Eukaryota
InParanoidiQ95168
OrthoDBi1175136at2759

Family and domain databases

CDDicd12027, SH3_ZO-2, 1 hit
Gene3Di2.30.42.10, 3 hits
InterProiView protein in InterPro
IPR008145, GK/Ca_channel_bsu
IPR008144, Guanylate_kin-like_dom
IPR027417, P-loop_NTPase
IPR001478, PDZ
IPR036034, PDZ_sf
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR005417, ZO
IPR005419, ZO-2
IPR035598, ZO-2_SH3
PfamiView protein in Pfam
PF00625, Guanylate_kin, 1 hit
PF00595, PDZ, 3 hits
PF07653, SH3_2, 1 hit
PRINTSiPR01597, ZONOCCLUDNS
PR01599, ZONOCCLUDNS2
SMARTiView protein in SMART
SM00072, GuKc, 1 hit
SM00228, PDZ, 3 hits
SUPFAMiSSF50044, SSF50044, 1 hit
SSF50156, SSF50156, 3 hits
SSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50052, GUANYLATE_KINASE_2, 1 hit
PS50106, PDZ, 3 hits
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZO2_CANLF
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q95168
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: February 1, 1997
Last modified: June 2, 2021
This is version 148 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again