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Entry version 99 (17 Jun 2020)
Sequence version 2 (19 Jul 2003)
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Protein

MLO-like protein 9

Gene

MLO9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca2+-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalmodulin-binding, Pathogenesis-related protein
Biological processPlant defense

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MLO-like protein 9
Short name:
AtMlo9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MLO9
Ordered Locus Names:At1g42560
ORF Names:F8D11.2, T8D8.5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G42560

The Arabidopsis Information Resource

More...
TAIRi
locus:2036650 AT1G42560

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 21ExtracellularSequence analysisAdd BLAST21
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini43 – 67CytoplasmicSequence analysisAdd BLAST25
Transmembranei68 – 88Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini89 – 158ExtracellularSequence analysisAdd BLAST70
Transmembranei159 – 179Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini180 – 289CytoplasmicSequence analysisAdd BLAST110
Transmembranei290 – 310Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini311 – 315ExtracellularSequence analysis5
Transmembranei316 – 336Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini337 – 366CytoplasmicSequence analysisAdd BLAST30
Transmembranei367 – 387Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini388 – 398ExtracellularSequence analysisAdd BLAST11
Transmembranei399 – 419Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini420 – 460CytoplasmicSequence analysisAdd BLAST41

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002099391 – 460MLO-like protein 9Add BLAST460

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q94KB4

PRoteomics IDEntifications database

More...
PRIDEi
Q94KB4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
238360

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q94KB4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q94KB4 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
26089, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q94KB4, 7 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G42560.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni441 – 460Calmodulin-bindingAdd BLAST20

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The C-terminus contains a calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MLO family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ4A Eukaryota
ENOG410YDNX LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_024720_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q94KB4

KEGG Orthology (KO)

More...
KOi
K08472

Database of Orthologous Groups

More...
OrthoDBi
603362at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q94KB4

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004326 Mlo

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03094 Mlo, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q94KB4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGGGGGGGG EGPRQLDQTP TWAVSTVCGV IILISIILEL IIHKVGEVFE
60 70 80 90 100
RKKKKALFEA LEKIKNELMV LGFISLLLTF GQNYIASICV PSRYGHAMSF
110 120 130 140 150
CGPYDGPSED DRKKLKKTDH AMRILYSVQR RSLADAPPVN CKKDYVALIS
160 170 180 190 200
LNALHQVHIF IFFLAVFHVI YSAITMMLGR AKIRGWKVWE QEVIHEQEMM
210 220 230 240 250
NDPSRFRLTH ETSFVREHVN SWASNKFFFY VMCFFRQILR SVRKSDYLTM
260 270 280 290 300
RHGFISVHLA PGMKFDFQKY IKRSLEDDFK VVVGIRPELW AFVMLFLLFD
310 320 330 340 350
VHGWYVTAVI TMIPPLLTLA IGTKLQAIIS YMALEIQERH AVIQGMPVVN
360 370 380 390 400
VSDQHFWFEK PDLVLHMIHF VLFQNAFEIT YFFWIWYEFG LRSCFHHHFG
410 420 430 440 450
LIIIRVCLGV GVQFLCSYIT LPLYALVTQM GSTMKRSVFD EQTSKALEQW
460
HKKARKKNEK
Length:460
Mass (Da):53,210
Last modified:July 19, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i739705B1DC08D34F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8ASU6A0A1P8ASU6_ARATH
Seven transmembrane MLO family prot...
MLO9 ATMLO9, MILDEW RESISTANCE LOCUS O 9, At1g42560, T8D8.5, T8D8_5
381Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG51234 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG51314 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC025815 Genomic DNA Translation: AAG51314.1 Sequence problems.
AC035249 Genomic DNA Translation: AAG51234.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE31927.1
AF369570 mRNA Translation: AAK53802.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E96495

NCBI Reference Sequences

More...
RefSeqi
NP_174980.3, NM_103440.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G42560.1; AT1G42560.1; AT1G42560

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
840861

Gramene; a comparative resource for plants

More...
Gramenei
AT1G42560.1; AT1G42560.1; AT1G42560

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G42560

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025815 Genomic DNA Translation: AAG51314.1 Sequence problems.
AC035249 Genomic DNA Translation: AAG51234.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE31927.1
AF369570 mRNA Translation: AAK53802.1
PIRiE96495
RefSeqiNP_174980.3, NM_103440.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi26089, 10 interactors
IntActiQ94KB4, 7 interactors
STRINGi3702.AT1G42560.1

Proteomic databases

PaxDbiQ94KB4
PRIDEiQ94KB4
ProteomicsDBi238360

Genome annotation databases

EnsemblPlantsiAT1G42560.1; AT1G42560.1; AT1G42560
GeneIDi840861
GrameneiAT1G42560.1; AT1G42560.1; AT1G42560
KEGGiath:AT1G42560

Organism-specific databases

AraportiAT1G42560
TAIRilocus:2036650 AT1G42560

Phylogenomic databases

eggNOGiENOG410IJ4A Eukaryota
ENOG410YDNX LUCA
HOGENOMiCLU_024720_3_0_1
InParanoidiQ94KB4
KOiK08472
OrthoDBi603362at2759
PhylomeDBiQ94KB4

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q94KB4

Gene expression databases

ExpressionAtlasiQ94KB4 baseline and differential
GenevisibleiQ94KB4 AT

Family and domain databases

InterProiView protein in InterPro
IPR004326 Mlo
PfamiView protein in Pfam
PF03094 Mlo, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMLO9_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q94KB4
Secondary accession number(s): Q9C855, Q9C8E5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2003
Last sequence update: July 19, 2003
Last modified: June 17, 2020
This is version 99 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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