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UniProtKB - Q94AU2 (SEC22_ARATH)
Protein
25.3 kDa vesicle transport protein
Gene
SEC22
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
V-SNARE involved in vesicle trafficking from the ER to the Golgi complex.
By similarityGO - Molecular functioni
- SNAP receptor activity Source: GO_Central
GO - Biological processi
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
- protein transport Source: UniProtKB-KW
- retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum Source: GO_Central
- vesicle fusion with Golgi apparatus Source: GO_Central
Keywordsi
Biological process | Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: 25.3 kDa vesicle transport proteinShort name: AtSEC22 |
Gene namesi | Name:SEC22 Ordered Locus Names:At1g11890 ORF Names:F12F1.27 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G11890 |
TAIRi | locus:2008960, AT1G11890 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Single-pass type IV membrane protein By similarity
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Single-pass type IV membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: TAIR
- endoplasmic reticulum membrane Source: GO_Central
Extracellular region or secreted
- extracellular region Source: TAIR
Golgi apparatus
- Golgi apparatus Source: TAIR
- Golgi membrane Source: GO_Central
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- endoplasmic reticulum-Golgi intermediate compartment Source: GO_Central
- ER to Golgi transport vesicle membrane Source: GO_Central
- integral component of membrane Source: UniProtKB-KW
- SNARE complex Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 192 | CytoplasmicSequence analysisAdd BLAST | 192 | |
Transmembranei | 193 – 213 | Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 214 – 218 | VesicularSequence analysis | 5 |
Keywords - Cellular componenti
Endoplasmic reticulum, Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206747 | 1 – 218 | 25.3 kDa vesicle transport proteinAdd BLAST | 218 |
Proteomic databases
PaxDbi | Q94AU2 |
PRIDEi | Q94AU2 |
ProteomicsDBi | 232829 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q94AU2, baseline and differential |
Genevisiblei | Q94AU2, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 22977, 10 interactors |
IntActi | Q94AU2, 10 interactors |
STRINGi | 3702.AT1G11890.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 120 | LonginPROSITE-ProRule annotationAdd BLAST | 115 | |
Domaini | 135 – 195 | v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST | 61 |
Sequence similaritiesi
Belongs to the synaptobrevin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0862, Eukaryota |
HOGENOMi | CLU_054453_4_1_1 |
InParanoidi | Q94AU2 |
OMAi | ERSYPRK |
OrthoDBi | 903466at2759 |
PhylomeDBi | Q94AU2 |
Family and domain databases
CDDi | cd14824, Longin, 1 hit |
InterProi | View protein in InterPro IPR011012, Longin-like_dom_sf IPR010908, Longin_dom IPR044565, Sec22 IPR042855, V_SNARE_CC |
PANTHERi | PTHR45837, PTHR45837, 1 hit |
Pfami | View protein in Pfam PF13774, Longin, 1 hit PF00957, Synaptobrevin, 1 hit |
SMARTi | View protein in SMART SM01270, Longin, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS50859, LONGIN, 1 hit PS50892, V_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q94AU2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVKMTLIARV TDGLPLAEGL DDGRDLPDSD MYKQQVKALF KNLSRGQNDA
60 70 80 90 100
SRMSVETGPY VFHYIIEGRV CYLTMCDRSY PKKLAFQYLE DLKNEFERVN
110 120 130 140 150
GPNIETAARP YAFIKFDTFI QKTKKLYQDT RTQRNIAKLN DELYEVHQIM
160 170 180 190 200
TRNVQEVLGV GEKLDQVSEM SSRLTSESRI YADKAKDLNR QALIRKWAPV
210
AIVFGVVFLL FWVKNKLW
Sequence cautioni
The sequence AAC17634 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002131 Genomic DNA Translation: AAC17634.1 Sequence problems. CP002684 Genomic DNA Translation: AEE28809.1 AY045795 mRNA Translation: AAK76469.1 AY079413 mRNA Translation: AAL85144.1 AY086749 mRNA Translation: AAM63800.1 |
PIRi | C86253 |
RefSeqi | NP_172653.1, NM_101060.4 |
Genome annotation databases
EnsemblPlantsi | AT1G11890.1; AT1G11890.1; AT1G11890 |
GeneIDi | 837737 |
Gramenei | AT1G11890.1; AT1G11890.1; AT1G11890 |
KEGGi | ath:AT1G11890 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002131 Genomic DNA Translation: AAC17634.1 Sequence problems. CP002684 Genomic DNA Translation: AEE28809.1 AY045795 mRNA Translation: AAK76469.1 AY079413 mRNA Translation: AAL85144.1 AY086749 mRNA Translation: AAM63800.1 |
PIRi | C86253 |
RefSeqi | NP_172653.1, NM_101060.4 |
3D structure databases
AlphaFoldDBi | Q94AU2 |
SMRi | Q94AU2 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 22977, 10 interactors |
IntActi | Q94AU2, 10 interactors |
STRINGi | 3702.AT1G11890.1 |
Proteomic databases
PaxDbi | Q94AU2 |
PRIDEi | Q94AU2 |
ProteomicsDBi | 232829 |
Genome annotation databases
EnsemblPlantsi | AT1G11890.1; AT1G11890.1; AT1G11890 |
GeneIDi | 837737 |
Gramenei | AT1G11890.1; AT1G11890.1; AT1G11890 |
KEGGi | ath:AT1G11890 |
Organism-specific databases
Araporti | AT1G11890 |
TAIRi | locus:2008960, AT1G11890 |
Phylogenomic databases
eggNOGi | KOG0862, Eukaryota |
HOGENOMi | CLU_054453_4_1_1 |
InParanoidi | Q94AU2 |
OMAi | ERSYPRK |
OrthoDBi | 903466at2759 |
PhylomeDBi | Q94AU2 |
Miscellaneous databases
PROi | PR:Q94AU2 |
Gene expression databases
ExpressionAtlasi | Q94AU2, baseline and differential |
Genevisiblei | Q94AU2, AT |
Family and domain databases
CDDi | cd14824, Longin, 1 hit |
InterProi | View protein in InterPro IPR011012, Longin-like_dom_sf IPR010908, Longin_dom IPR044565, Sec22 IPR042855, V_SNARE_CC |
PANTHERi | PTHR45837, PTHR45837, 1 hit |
Pfami | View protein in Pfam PF13774, Longin, 1 hit PF00957, Synaptobrevin, 1 hit |
SMARTi | View protein in SMART SM01270, Longin, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS50859, LONGIN, 1 hit PS50892, V_SNARE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SEC22_ARATH | |
Accessioni | Q94AU2Primary (citable) accession number: Q94AU2 Secondary accession number(s): O65393 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 17, 2003 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 142 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families