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Entry version 91 (16 Oct 2019)
Sequence version 2 (10 Jul 2007)
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Protein

Protein arginine N-methyltransferase 1.6

Gene

PRMT16

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei183By similarity1
Active sitei192By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase
LigandS-adenosyl-L-methionine

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein arginine N-methyltransferase 1.6 (EC:2.1.1.-)
Short name:
AtPRMT16
Short name:
AtPRMT7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRMT16
Synonyms:PRMT7
Ordered Locus Names:At4g16570
ORF Names:dl4310w, FCAALL.195
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G16570

The Arabidopsis Information Resource

More...
TAIRi
locus:2130824 AT4G16570

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002940011 – 724Protein arginine N-methyltransferase 1.6Add BLAST724

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q944R7

PRoteomics IDEntifications database

More...
PRIDEi
Q944R7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q944R7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q944R7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q944R7 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT4G16570.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q944R7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini61 – 388SAM-dependent MTase PRMT-type 1PROSITE-ProRule annotationAdd BLAST328
Domaini395 – 721SAM-dependent MTase PRMT-type 2PROSITE-ProRule annotationAdd BLAST327

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1501 Eukaryota
ENOG410XPR8 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000030859

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q944R7

KEGG Orthology (KO)

More...
KOi
K11438

Identification of Orthologs from Complete Genome Data

More...
OMAi
VPWRDHW

Database of Orthologous Groups

More...
OrthoDBi
408622at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q944R7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025799 Arg_MeTrfase
IPR014644 MeTrfase_PRMT7
IPR029063 SAM-dependent_MTases

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036946 Arg_N-mtase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335 SSF53335, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51678 SAM_MT_PRMT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q944R7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSPLSSLPPK TFISSFHCHS VTRLRRSVTA RTMSSQSSQR VFQLRQDPLT
60 70 80 90 100
GNSEWIVIED NDQPGTSTDG LLATTSYLDM LNDSRRNIAY RLAIEKTITE
110 120 130 140 150
PCHVLDIGAG TGLLSMMAVR AMRGDSKGMV TACESYLPMV KLMRKVMHKN
160 170 180 190 200
GMTKNINLIN KRSDELKVGS EDIASRADVL VSEILDSELL GEGLIPSLQH
210 220 230 240 250
AHDMLLVDNP KTVPYRATTY CQLVESTFLC NLQDLRNNEA KTSDGVRLVP
260 270 280 290 300
PGLESLFGIK SQQYSMHVDA IEKEIKLLSE PVKIFEFDFW KRPESNGELD
310 320 330 340 350
VHIEAKTTGS VHAIISWWVL QLDSEGTIFY STAPRWIDSN SEIGVRDWCD
360 370 380 390 400
HWKQCVWFTP GTGVSISKGE KVHLHASHTC TNILYNLKKT QSLTHERTHF
410 420 430 440 450
PLSTGDLHLT LPPERVAIYG DSIYRQSLFE ATRKALQGKS YPQCLVIDDS
460 470 480 490 500
LLLPLMALHI SNRSRVLSLS PGLQENAARY FEAIADSNGF SKDRFEYFRD
510 520 530 540 550
GKTNLAKAYP GKIDLLIGEP YYSGLENGLP WQNLRFWKDR TLLDSVLSED
560 570 580 590 600
AVVMPYKGVL RGCAMYLPDL WKSRCCLGSV EGFDHTLVNT TLGGCGDLPS
610 620 630 640 650
GKDSPCLPFF IWQCGETKIL SKEFTVMEFD FSKPITGPCS GEVQIEFIKP
660 670 680 690 700
GVCHGIALWM DWVMDEENST VISTGPDDKY WKQGVKLLGK PVTVRMEGPS
710 720
SSIGIQASLD LSSNSELIVT HTIS
Length:724
Mass (Da):80,870
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A26FFCA4665B5D2
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL11573 differs from that shown. Reason: Frameshift.Curated
The sequence AAN18172 differs from that shown. Reason: Frameshift.Curated
The sequence CAB10433 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB78699 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti634P → S in AAN18172 (PubMed:14593172).Curated1
Sequence conflicti634P → S in AAL11573 (PubMed:14593172).Curated1
Sequence conflicti660M → V in AAN18172 (PubMed:14593172).Curated1
Sequence conflicti660M → V in AAL11573 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z97341 Genomic DNA Translation: CAB10433.1 Sequence problems.
AL161544 Genomic DNA Translation: CAB78699.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83772.1
AF424579 mRNA Translation: AAL11573.1 Frameshift.
BT000603 mRNA Translation: AAN18172.1 Frameshift.

Protein sequence database of the Protein Information Resource

More...
PIRi
G71432

NCBI Reference Sequences

More...
RefSeqi
NP_567508.1, NM_117758.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G16570.1; AT4G16570.1; AT4G16570

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
827358

Gramene; a comparative resource for plants

More...
Gramenei
AT4G16570.1; AT4G16570.1; AT4G16570

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G16570

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97341 Genomic DNA Translation: CAB10433.1 Sequence problems.
AL161544 Genomic DNA Translation: CAB78699.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83772.1
AF424579 mRNA Translation: AAL11573.1 Frameshift.
BT000603 mRNA Translation: AAN18172.1 Frameshift.
PIRiG71432
RefSeqiNP_567508.1, NM_117758.3

3D structure databases

SMRiQ944R7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G16570.1

PTM databases

iPTMnetiQ944R7

Proteomic databases

PaxDbiQ944R7
PRIDEiQ944R7

Genome annotation databases

EnsemblPlantsiAT4G16570.1; AT4G16570.1; AT4G16570
GeneIDi827358
GrameneiAT4G16570.1; AT4G16570.1; AT4G16570
KEGGiath:AT4G16570

Organism-specific databases

AraportiAT4G16570
TAIRilocus:2130824 AT4G16570

Phylogenomic databases

eggNOGiKOG1501 Eukaryota
ENOG410XPR8 LUCA
HOGENOMiHOG000030859
InParanoidiQ944R7
KOiK11438
OMAiVPWRDHW
OrthoDBi408622at2759
PhylomeDBiQ944R7

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q944R7

Gene expression databases

ExpressionAtlasiQ944R7 baseline and differential
GenevisibleiQ944R7 AT

Family and domain databases

InterProiView protein in InterPro
IPR025799 Arg_MeTrfase
IPR014644 MeTrfase_PRMT7
IPR029063 SAM-dependent_MTases
PIRSFiPIRSF036946 Arg_N-mtase, 1 hit
SUPFAMiSSF53335 SSF53335, 2 hits
PROSITEiView protein in PROSITE
PS51678 SAM_MT_PRMT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANM16_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q944R7
Secondary accession number(s): O23501
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: October 16, 2019
This is version 91 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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