UniProtKB - Q944I4 (GLYK_ARATH)
D-glycerate 3-kinase, chloroplastic
GLYK
Functioni
Catalyzes the concluding reaction of the photorespiratory C2 cycle, an indispensable ancillary metabolic pathway to the photosynthetic C3 cycle that enables land plants to grow in an oxygen-containing atmosphere.
1 PublicationCytoplasmic D-glycerate 3-kinase that constitutes a photorespiratory bypass that alleviates fluctuating light-induced photoinhibition (PubMed:29129375).
1 PublicationCatalytic activityi
- EC:2.7.1.311 Publication
: photorespiration Pathwayi
This protein is involved in step 4 of the subpathway that synthesizes 3-phospho-D-glycerate from glycine.Curated This subpathway is part of the pathway photorespiration, which is itself part of Photosynthesis.View all proteins of this organism that are known to be involved in the subpathway that synthesizes 3-phospho-D-glycerate from glycine, the pathway photorespiration and in Photosynthesis.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 215 – 222 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- glycerate kinase activity Source: TAIR
GO - Biological processi
- oxidative photosynthetic carbon pathway Source: UniProtKB-UniPathway
- photorespiration Source: TAIR
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Glycolate pathway, Photorespiration |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | ARA:AT1G80380-MONOMER |
BRENDAi | 2.7.1.31, 399 |
UniPathwayi | UPA00951;UER00917 |
Names & Taxonomyi
Protein namesi | Recommended name: D-glycerate 3-kinase, chloroplasticCurated (EC:2.7.1.311 Publication)Short name: AtGLYK1 Publication |
Gene namesi | Name:GLYK1 Publication Ordered Locus Names:At1g80380Imported ORF Names:F5I6.13Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G80380 |
TAIRi | locus:2034260, AT1G80380 |
Subcellular locationi
Chloroplast
- chloroplast 1 Publication
Note: Expressed in the light.1 Publication
Cytoplasm and Cytosol
- Cytoplasm 1 Publication
Note: Expressed in the dark.1 Publication
Chloroplast
- chloroplast Source: TAIR
- chloroplast envelope Source: TAIR
- chloroplast stroma Source: TAIR
Mitochondrion
- mitochondrion Source: TAIR
Other locations
- cytoplasm Source: UniProtKB
Keywords - Cellular componenti
Chloroplast, Cytoplasm, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 63 | ChloroplastSequence analysisAdd BLAST | 63 | |
ChainiPRO_0000012282 | 64 – 456 | D-glycerate 3-kinase, chloroplasticAdd BLAST | 393 |
Proteomic databases
PaxDbi | Q944I4 |
PTM databases
iPTMneti | Q944I4 |
Expressioni
Inductioni
Gene expression databases
ExpressionAtlasi | Q944I4, baseline and differential |
Genevisiblei | Q944I4, AT |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG2878, Eukaryota |
InParanoidi | Q944I4 |
PhylomeDBi | Q944I4 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR006083, PRK/URK |
Pfami | View protein in Pfam PF00485, PRK, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAVAISGSSL ISSTLQHYNN RIYIRDYPIP CHSSNPICNS FNFKRRSFSP
60 70 80 90 100
SSPKFNDHVV NPSSSYLSSK LSPIRTHSSF AACGCSWIQD NSMVHDYATT
110 120 130 140 150
TNGTSKRCSA LPTTNTVDVS SVSDLFEFIC SGPLVNKIGI TPQRVGQSID
160 170 180 190 200
KWLLYGSQLC RLFQLNELKL TIPQKARLYH YYIPVFIWCE DQIALHNSKF
210 220 230 240 250
KDGDDVPPLV IGFSAPQGCG KTTLVFALDY LFKTTKKKSA TISVDDFYLT
260 270 280 290 300
AEGQAELRKK NPGNALLEYR GNAGSHDLKL SVETLEALSK LTKEGLKMKV
310 320 330 340 350
PRYNKSAYSG RGDRADSSTW PEVEGPLSVI LFEGWMLGFK PLPADVVKAV
360 370 380 390 400
DPQLEVVNKN LEAYYDAWDK YIDAWVVIKI QDPSYVYRWR LQAEIAMRQD
410 420 430 440 450
GQAGMSDEEV NDFVSRYLPA YKAYLPTLYA EGPSGSDPDR VLAIDIDEER
NPILAN
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8AMB5 | A0A1P8AMB5_ARATH | p-loop containing nucleoside tripho... | At1g80380, F5I6.13, F5I6_13 | 323 | Annotation score: | ||
C0Z2X8 | C0Z2X8_ARATH | AT1G80380 protein | At1g80380, F5I6.13, F5I6_13 | 325 | Annotation score: | ||
A0A1P8AMB3 | A0A1P8AMB3_ARATH | p-loop containing nucleoside tripho... | At1g80380, F5I6.13, F5I6_13 | 390 | Annotation score: | ||
F4HS63 | F4HS63_ARATH | p-loop containing nucleoside tripho... | At1g80380, F5I6.13, F5I6_13 | 450 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 188 | W → C in AAM61346 (Ref. 4) Curated | 1 | |
Sequence conflicti | 239 | S → P in AAL16169 (PubMed:14593172).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_059299 | 1 – 92 | Missing in isoform 3. Add BLAST | 92 | |
Alternative sequenceiVSP_015208 | 206 – 299 | Missing in isoform 2. CuratedAdd BLAST | 94 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018848 Genomic DNA Translation: AAG52441.1 Sequence problems. CP002684 Genomic DNA Translation: AEE36393.1 CP002684 Genomic DNA Translation: AEE36394.1 CP002684 Genomic DNA Translation: AEE36395.1 AF360156 mRNA Translation: AAK25866.1 AF428401 mRNA Translation: AAL16169.1 AY056310 mRNA Translation: AAL07159.1 AY084779 mRNA Translation: AAM61346.1 |
PIRi | E96835 |
RefSeqi | NP_001077855.1, NM_001084386.2 [Q944I4-3] NP_565237.1, NM_106687.2 [Q944I4-2] NP_849912.1, NM_179581.3 [Q944I4-1] |
Genome annotation databases
EnsemblPlantsi | AT1G80380.1; AT1G80380.1; AT1G80380 [Q944I4-2] AT1G80380.2; AT1G80380.2; AT1G80380 [Q944I4-1] AT1G80380.3; AT1G80380.3; AT1G80380 [Q944I4-3] |
GeneIDi | 844378 |
Gramenei | AT1G80380.1; AT1G80380.1; AT1G80380 [Q944I4-2] AT1G80380.2; AT1G80380.2; AT1G80380 [Q944I4-1] AT1G80380.3; AT1G80380.3; AT1G80380 [Q944I4-3] |
KEGGi | ath:AT1G80380 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018848 Genomic DNA Translation: AAG52441.1 Sequence problems. CP002684 Genomic DNA Translation: AEE36393.1 CP002684 Genomic DNA Translation: AEE36394.1 CP002684 Genomic DNA Translation: AEE36395.1 AF360156 mRNA Translation: AAK25866.1 AF428401 mRNA Translation: AAL16169.1 AY056310 mRNA Translation: AAL07159.1 AY084779 mRNA Translation: AAM61346.1 |
PIRi | E96835 |
RefSeqi | NP_001077855.1, NM_001084386.2 [Q944I4-3] NP_565237.1, NM_106687.2 [Q944I4-2] NP_849912.1, NM_179581.3 [Q944I4-1] |
3D structure databases
SMRi | Q944I4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT1G80380.2 |
PTM databases
iPTMneti | Q944I4 |
Proteomic databases
PaxDbi | Q944I4 |
Genome annotation databases
EnsemblPlantsi | AT1G80380.1; AT1G80380.1; AT1G80380 [Q944I4-2] AT1G80380.2; AT1G80380.2; AT1G80380 [Q944I4-1] AT1G80380.3; AT1G80380.3; AT1G80380 [Q944I4-3] |
GeneIDi | 844378 |
Gramenei | AT1G80380.1; AT1G80380.1; AT1G80380 [Q944I4-2] AT1G80380.2; AT1G80380.2; AT1G80380 [Q944I4-1] AT1G80380.3; AT1G80380.3; AT1G80380 [Q944I4-3] |
KEGGi | ath:AT1G80380 |
Organism-specific databases
Araporti | AT1G80380 |
TAIRi | locus:2034260, AT1G80380 |
Phylogenomic databases
eggNOGi | KOG2878, Eukaryota |
InParanoidi | Q944I4 |
PhylomeDBi | Q944I4 |
Enzyme and pathway databases
UniPathwayi | UPA00951;UER00917 |
BioCyci | ARA:AT1G80380-MONOMER |
BRENDAi | 2.7.1.31, 399 |
Miscellaneous databases
PROi | PR:Q944I4 |
Gene expression databases
ExpressionAtlasi | Q944I4, baseline and differential |
Genevisiblei | Q944I4, AT |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR006083, PRK/URK |
Pfami | View protein in Pfam PF00485, PRK, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GLYK_ARATH | |
Accessioni | Q944I4Primary (citable) accession number: Q944I4 Secondary accession number(s): A8MQE0 Q9C967 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 30, 2005 |
Last sequence update: | August 30, 2005 | |
Last modified: | February 23, 2022 | |
This is version 128 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families