UniProtKB - Q944A6 (SNF4_ARATH)
Sucrose nonfermenting 4-like protein
SNF4
Functioni
Regulatory subunit of the probable trimeric SNF1-related protein kinase (SnRK) complex, which may play a role in a signal transduction cascade regulating gene expression and carbohydrate metabolism in higher plants.
GO - Molecular functioni
- AMP binding Source: GO_Central
- kinase binding Source: UniProtKB
- maltose binding Source: TAIR
- protein kinase activator activity Source: TAIR
- protein kinase binding Source: GO_Central
- protein kinase regulator activity Source: TAIR
- protein serine/threonine kinase activity Source: TAIR
GO - Biological processi
- carbohydrate metabolic process Source: UniProtKB-KW
- cellular response to glucose starvation Source: TAIR
- mitochondrial fission Source: TAIR
- peroxisome fission Source: TAIR
- pollen hydration Source: TAIR
- protein autophosphorylation Source: TAIR
- protein phosphorylation Source: GO_Central
- regulation of catalytic activity Source: GO_Central
- regulation of protein kinase activity Source: TAIR
- regulation of reactive oxygen species metabolic process Source: TAIR
Keywordsi
Biological process | Carbohydrate metabolism |
Protein family/group databases
CAZyi | CBM48, Carbohydrate-Binding Module Family 48 |
Names & Taxonomyi
Protein namesi | Recommended name: Sucrose nonfermenting 4-like proteinShort name: SNF4 Alternative name(s): CBS domain-containing protein CBSCBS3 SNF1-related protein kinase regulatory subunit betagamma Short name: AKIN subunit betagamma Short name: AKINbetagamma |
Gene namesi | Name:SNF4 Synonyms:CBSCBS3 Ordered Locus Names:At1g09020 ORF Names:F7G19.11 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G09020 |
TAIRi | locus:2036079, AT1G09020 |
Subcellular locationi
Chloroplast
- chloroplast Source: TAIR
- chloroplast starch grain Source: TAIR
Nucleus
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB
- nucleotide-activated protein kinase complex Source: GO_Central
Keywords - Cellular componenti
Cytoplasm, NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000412195 | 1 – 487 | Sucrose nonfermenting 4-like proteinAdd BLAST | 487 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | Q944A6 |
PRIDEi | Q944A6 |
ProteomicsDBi | 232545 [Q944A6-1] |
PTM databases
iPTMneti | Q944A6 |
Expressioni
Tissue specificityi
Gene expression databases
ExpressionAtlasi | Q944A6, baseline and differential |
Genevisiblei | Q944A6, AT |
Interactioni
Subunit structurei
Subunit of a probable heterotrimeric complex consisting of an alpha catalytic (KIN10 or KIN11) subunit, and a beta (KINB) and a gamma (KING or SNF4) non-catalytic regulatory subunits (PubMed:17028154, PubMed:25736509).
Interacts with KIN10, KIN11, KINB1, KINB2, KINB3, HSPRO1 AND HSPRO2.
Interacts with BZIP63 (PubMed:26263501).
Interacts with FLZ2, FLZ8 and FLZ13 (PubMed:29945970).
7 PublicationsBinary interactionsi
Q944A6
GO - Molecular functioni
- kinase binding Source: UniProtKB
- protein kinase binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 22664, 67 interactors |
IntActi | Q944A6, 9 interactors |
STRINGi | 3702.AT1G09020.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 165 – 227 | CBS 1PROSITE-ProRule annotationAdd BLAST | 63 | |
Domaini | 260 – 324 | CBS 2PROSITE-ProRule annotationAdd BLAST | 65 | |
Domaini | 350 – 408 | CBS 3PROSITE-ProRule annotationAdd BLAST | 59 | |
Domaini | 432 – 487 | CBS 4PROSITE-ProRule annotationAdd BLAST | 56 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 22 – 101 | Kinase-interacting sequence (KIS)Add BLAST | 80 |
Domaini
Sequence similaritiesi
Keywords - Domaini
CBS domain, RepeatPhylogenomic databases
eggNOGi | KOG1616, Eukaryota KOG1764, Eukaryota |
HOGENOMi | CLU_021740_7_1_1 |
InParanoidi | Q944A6 |
OMAi | ACVKMLE |
PhylomeDBi | Q944A6 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.580.10, 2 hits |
InterProi | View protein in InterPro IPR032640, AMPK1_CBM IPR000644, CBS_dom IPR046342, CBS_dom_sf IPR013783, Ig-like_fold IPR014756, Ig_E-set |
Pfami | View protein in Pfam PF16561, AMPK1_CBM, 1 hit PF00571, CBS, 2 hits |
SMARTi | View protein in SMART SM00116, CBS, 3 hits |
SUPFAMi | SSF54631, SSF54631, 2 hits SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 4 hits |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFGSTLDSSR GNSAASGQLL TPTRFVWPYG GRRVFLSGSF TRWTEHVPMS
60 70 80 90 100
PLEGCPTVFQ VICNLTPGYH QYKFFVDGEW RHDEHQPFVS GNGGVVNTIF
110 120 130 140 150
ITGPDMVPAG FSPETLGRSN MDVDDVFLRT ADPSQEAVPR MSGVDLELSR
160 170 180 190 200
HRISVLLSTR TAYELLPESG KVIALDVNLP VKQAFHILYE QGIPLAPLWD
210 220 230 240 250
FGKGQFVGVL GPLDFILILR ELGTHGSNLT EEELETHTIA AWKEGKAHIS
260 270 280 290 300
RQYDGSGRPY PRPLVQVGPY DNLKDVALKI LQNKVAAVPV IYSSLQDGSY
310 320 330 340 350
PQLLHLASLS GILKCICRYF RHSSSSLPIL QQPICSIPLG TWVPRIGESS
360 370 380 390 400
SKPLATLRPH ASLGSALALL VQAEVSSIPV VDDNDSLIDI YSRSDITALA
410 420 430 440 450
KDKAYAQIHL DDMTVHQALQ LGQDASPPYG IFNGQRCHMC LRSDSLVKVM
460 470 480
ERLANPGVRR LVIVEAGSKR VEGIISLSDV FQFLLGL
Sequence cautioni
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_041656 | 394 | S → R in isoform 2. 1 Publication | 1 | |
Alternative sequenceiVSP_041657 | 395 – 487 | Missing in isoform 2. 1 PublicationAdd BLAST | 93 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF250335 mRNA Translation: AAG10141.1 Different initiation. DQ132632 mRNA Translation: ABA12450.1 DQ132633 mRNA Translation: ABA12451.1 AC000106 Genomic DNA Translation: AAB70406.1 Sequence problems. CP002684 Genomic DNA Translation: AEE28383.1 AF439826 mRNA Translation: AAL27498.1 BT000625 mRNA Translation: AAN18191.1 |
PIRi | B86222 |
RefSeqi | NP_563834.1, NM_100773.4 [Q944A6-1] |
Genome annotation databases
EnsemblPlantsi | AT1G09020.1; AT1G09020.1; AT1G09020 [Q944A6-1] |
GeneIDi | 837423 |
Gramenei | AT1G09020.1; AT1G09020.1; AT1G09020 [Q944A6-1] |
KEGGi | ath:AT1G09020 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF250335 mRNA Translation: AAG10141.1 Different initiation. DQ132632 mRNA Translation: ABA12450.1 DQ132633 mRNA Translation: ABA12451.1 AC000106 Genomic DNA Translation: AAB70406.1 Sequence problems. CP002684 Genomic DNA Translation: AEE28383.1 AF439826 mRNA Translation: AAL27498.1 BT000625 mRNA Translation: AAN18191.1 |
PIRi | B86222 |
RefSeqi | NP_563834.1, NM_100773.4 [Q944A6-1] |
3D structure databases
AlphaFoldDBi | Q944A6 |
SMRi | Q944A6 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 22664, 67 interactors |
IntActi | Q944A6, 9 interactors |
STRINGi | 3702.AT1G09020.1 |
Protein family/group databases
CAZyi | CBM48, Carbohydrate-Binding Module Family 48 |
PTM databases
iPTMneti | Q944A6 |
Proteomic databases
PaxDbi | Q944A6 |
PRIDEi | Q944A6 |
ProteomicsDBi | 232545 [Q944A6-1] |
Genome annotation databases
EnsemblPlantsi | AT1G09020.1; AT1G09020.1; AT1G09020 [Q944A6-1] |
GeneIDi | 837423 |
Gramenei | AT1G09020.1; AT1G09020.1; AT1G09020 [Q944A6-1] |
KEGGi | ath:AT1G09020 |
Organism-specific databases
Araporti | AT1G09020 |
TAIRi | locus:2036079, AT1G09020 |
Phylogenomic databases
eggNOGi | KOG1616, Eukaryota KOG1764, Eukaryota |
HOGENOMi | CLU_021740_7_1_1 |
InParanoidi | Q944A6 |
OMAi | ACVKMLE |
PhylomeDBi | Q944A6 |
Miscellaneous databases
PROi | PR:Q944A6 |
Gene expression databases
ExpressionAtlasi | Q944A6, baseline and differential |
Genevisiblei | Q944A6, AT |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.580.10, 2 hits |
InterProi | View protein in InterPro IPR032640, AMPK1_CBM IPR000644, CBS_dom IPR046342, CBS_dom_sf IPR013783, Ig-like_fold IPR014756, Ig_E-set |
Pfami | View protein in Pfam PF16561, AMPK1_CBM, 1 hit PF00571, CBS, 2 hits |
SMARTi | View protein in SMART SM00116, CBS, 3 hits |
SUPFAMi | SSF54631, SSF54631, 2 hits SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | SNF4_ARATH | |
Accessioni | Q944A6Primary (citable) accession number: Q944A6 Secondary accession number(s): O04028, Q2QCL5, Q9FV59 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 27, 2011 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 126 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families