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Entry version 169 (02 Jun 2021)
Sequence version 1 (01 Feb 1997)
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Protein

DnaJ homolog subfamily C member 2

Gene

dnj-11

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DnaJ homolog subfamily C member 2ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:dnj-11Imported
ORF Names:CELE_F38A5.13Imported, F38A5.13Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome IV

Organism-specific databases

WormBase

More...
WormBasei
F38A5.13 ; CE10050 ; WBGene00001029 ; dnj-11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q94216

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q94216

PeptideAtlas

More...
PeptideAtlasi
Q94216

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00001029, Expressed in adult organism and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

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DIPi
DIP-25497N

STRING: functional protein association networks

More...
STRINGi
6239.F38A5.13

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q94216

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini98 – 170JInterPro annotationAdd BLAST73
Domaini448 – 504Myb-likeInterPro annotationAdd BLAST57

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni248 – 271DisorderedSequence analysisAdd BLAST24
Regioni294 – 377DisorderedSequence analysisAdd BLAST84

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0724, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000173125

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_019916_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q94216

Identification of Orthologs from Complete Genome Data

More...
OMAi
TTPDRWD

Database of Orthologous Groups

More...
OrthoDBi
1392575at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q94216

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06257, DnaJ, 1 hit
cd00167, SANT, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.287.110, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001623, DnaJ_domain
IPR009057, Homeobox-like_sf
IPR036869, J_dom_sf
IPR017877, Myb-like_dom
IPR032003, RAC_head
IPR001005, SANT/Myb
IPR044634, Zuotin/DnaJC2

The PANTHER Classification System

More...
PANTHERi
PTHR43999, PTHR43999, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00226, DnaJ, 1 hit
PF00249, Myb_DNA-binding, 1 hit
PF16717, RAC_head, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00271, DnaJ, 1 hit
SM00717, SANT, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46565, SSF46565, 1 hit
SSF46689, SSF46689, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50076, DNAJ_2, 1 hit
PS50090, MYB_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q94216-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTGNLQVAI YGFTARSRAF EPAGICYETR LIRDKLTLGH CTLPIYKNSP
60 70 80 90 100
VAKPVTEQQR KKSSEEPAEL RKDLFDADNE KYEKYLMKLD PNDCKNQDHY
110 120 130 140 150
KVLGLSKLRW QATSDEIRFC YRQKVLKHHP DKKKHRGIVM EKEEYFTCIT
160 170 180 190 200
KAYEQVGMSD VKRQAFDSVD HKFNDIIPNE KSINHNNFYN ELAPVFQLNS
210 220 230 240 250
RWSNIKPVPE LGKSDATRED VENFYDFWFN FQSWREFSYL DEEDKERGED
260 270 280 290 300
RYERREMEKQ NKAERERRRK EEAKRIRKLV DIAYAKDPRI IKFKKEQQAK
310 320 330 340 350
KDKAKEDKQR AIREKQEAID REKREKEEAE AKQKEEADRK AKEEREREKK
360 370 380 390 400
ERDIAKKAMS QQRKRLKKLA DEAGHWTENP RDKLTEMERI ERICIGFTVD
410 420 430 440 450
QLRELCEKVE SLSIASEIQT ALTDAEILKK EAAGAKVTIT EDKNKENEKQ
460 470 480 490 500
ADKETWTSEE IQLLVKASNT FPPGTVERWV QIADYINEHR KDSTGLPPKT
510 520 530 540 550
EKQVIKQCKA VQTMNVKLPS TTQNQLGTAL PDEDVWSATE QKTLEDAIKK
560 570 580
HKSSDPERWE KISTEVGTKS KKACIRRFKY LVQMVKNKK
Length:589
Mass (Da):69,414
Last modified:February 1, 1997 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD3CF39ED6B3EEDD9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD67179.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T29895

NCBI Reference Sequences

More...
RefSeqi
NP_501006.1, NM_068605.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F38A5.13.1; F38A5.13.1; WBGene00001029

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
177419

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F38A5.13

UCSC genome browser

More...
UCSCi
F38A5.13, c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD67179.1
PIRiT29895
RefSeqiNP_501006.1, NM_068605.4

3D structure databases

SMRiQ94216
ModBaseiSearch...

Protein-protein interaction databases

DIPiDIP-25497N
STRINGi6239.F38A5.13

Proteomic databases

EPDiQ94216
PaxDbiQ94216
PeptideAtlasiQ94216

Genome annotation databases

EnsemblMetazoaiF38A5.13.1; F38A5.13.1; WBGene00001029
GeneIDi177419
KEGGicel:CELE_F38A5.13
UCSCiF38A5.13, c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
177419
WormBaseiF38A5.13 ; CE10050 ; WBGene00001029 ; dnj-11

Phylogenomic databases

eggNOGiKOG0724, Eukaryota
GeneTreeiENSGT00940000173125
HOGENOMiCLU_019916_0_0_1
InParanoidiQ94216
OMAiTTPDRWD
OrthoDBi1392575at2759
PhylomeDBiQ94216

Gene expression databases

BgeeiWBGene00001029, Expressed in adult organism and 5 other tissues

Family and domain databases

CDDicd06257, DnaJ, 1 hit
cd00167, SANT, 2 hits
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623, DnaJ_domain
IPR009057, Homeobox-like_sf
IPR036869, J_dom_sf
IPR017877, Myb-like_dom
IPR032003, RAC_head
IPR001005, SANT/Myb
IPR044634, Zuotin/DnaJC2
PANTHERiPTHR43999, PTHR43999, 1 hit
PfamiView protein in Pfam
PF00226, DnaJ, 1 hit
PF00249, Myb_DNA-binding, 1 hit
PF16717, RAC_head, 1 hit
SMARTiView protein in SMART
SM00271, DnaJ, 1 hit
SM00717, SANT, 2 hits
SUPFAMiSSF46565, SSF46565, 1 hit
SSF46689, SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS50076, DNAJ_2, 1 hit
PS50090, MYB_LIKE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ94216_CAEEL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q94216
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: June 2, 2021
This is version 169 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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