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Protein

Laccase-3

Gene

LAC3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi82Copper 1By similarity1
Metal bindingi84Copper 2By similarity1
Metal bindingi127Copper 2By similarity1
Metal bindingi129Copper 3By similarity1
Metal bindingi468Copper 4By similarity1
Metal bindingi471Copper 1By similarity1
Metal bindingi473Copper 3By similarity1
Metal bindingi530Copper 3By similarity1
Metal bindingi531Copper 4By similarity1
Metal bindingi532Copper 2By similarity1
Metal bindingi536Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-3 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 3
Diphenol oxidase 3
Urishiol oxidase 3
Gene namesi
Name:LAC3
Ordered Locus Names:Os01g0827300, LOC_Os01g61160
ORF Names:B1088C09.5, OsJ_03932Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000029188825 – 567Laccase-3Add BLAST543

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi78N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi148N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi187N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi203N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi298N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi330N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi379N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi389N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ941X2

Expressioni

Gene expression databases

ExpressionAtlasiQ941X2 differential
GenevisibleiQ941X2 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g61160.1

Structurei

3D structure databases

ProteinModelPortaliQ941X2
SMRiQ941X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 148Plastocyanin-like 1Add BLAST117
Domaini158 – 310Plastocyanin-like 2Add BLAST153
Domaini415 – 551Plastocyanin-like 3Add BLAST137

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
HOGENOMiHOG000241916
InParanoidiQ941X2
KOiK05909
OMAiCLVYSCA
OrthoDBiEOG093605O6

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
cd13897 CuRO_3_LCC_plant, 1 hit
Gene3Di2.60.40.420, 3 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR034289 CuRO_3_LCC
IPR017761 Laccase
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 4 hits
TIGRFAMsiTIGR03389 laccase, 1 hit
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q941X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSSSRLL FLLSCSVLAL LAGAEVHHHE FIVQETPVKR LCKTHNVITV
60 70 80 90 100
NGQLPGPTLE VREGDTVVIN VVNHAQYNVT IHWHGIRQFR TGWADGPEFV
110 120 130 140 150
TQCPIKPGGS YKYRFTIEGQ EGTLWWHAHS SWLRATVYGA LIIRPRENKT
160 170 180 190 200
YPFEKPAREV PLILGEWWDA DPIQVIREAQ RTGAAPNISD AYTINGQPGD
210 220 230 240 250
LYNCSKEETT AVPVKPGETA LLRFINAALN QELFVSIAQH KMTVVGVDAS
260 270 280 290 300
YTKPFTTSVL MIAPGQTTDV LVTMDQAPTR YYLAARAYDS AQGVAFDNTT
310 320 330 340 350
TTAVIEYDCG CATDFGPSIP PAFPVLPAFN DTNTATAFAA GIRSPHEVKI
360 370 380 390 400
PGPVDENLFF TVGVGLFNCE PGQQCGGPNN TRFTASMNNI SFVFPQTTSL
410 420 430 440 450
LHAHYYGIPG VFTTDFPAYP PVQFDYTAQN VPRYLWQPVP ATKLYKLKFG
460 470 480 490 500
SVVQIVLQDT SIVSPENHPI HIHGYDFYIL AEGFGNFDPK KDAKKFNYVD
510 520 530 540 550
PPQRNTVAVP TNGWAVIRFV ADNPGVWLMH CHLDVHITWG LAMAFLVEDG
560
YGKLETLEAP PVDLPMC
Length:567
Mass (Da):62,646
Last modified:December 1, 2001 - v1
Checksum:iFA8603416C584361
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003734 Genomic DNA Translation: BAB68098.1
AP008207 Genomic DNA Translation: BAF06593.1
AP014957 Genomic DNA Translation: BAS75026.1
CM000138 Genomic DNA Translation: EEE55611.1
AK071929 mRNA Translation: BAG92758.1
RefSeqiXP_015624567.1, XM_015769081.1
UniGeneiOs.34310

Genome annotation databases

EnsemblPlantsiOs01t0827300-01; Os01t0827300-01; Os01g0827300
GeneIDi4327522
GrameneiOs01t0827300-01; Os01t0827300-01; Os01g0827300
KEGGiosa:4327522

Similar proteinsi

Entry informationi

Entry nameiLAC3_ORYSJ
AccessioniPrimary (citable) accession number: Q941X2
Secondary accession number(s): B7EK61
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

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