UniProtKB - Q93ZL5 (CDF2_ARATH)
Protein
Cyclic dof factor 2
Gene
CDF2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3, ADO2 and/or ADO1.By similarity1 Publication
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 138 – 192 | Dof-typePROSITE-ProRule annotationAdd BLAST | 55 |
GO - Molecular functioni
- DNA binding Source: GO_Central
- DNA-binding transcription factor activity Source: TAIR
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- flower development Source: UniProtKB-KW
- regulation of transcription, DNA-templated Source: TAIR
Keywordsi
Molecular function | DNA-binding |
Biological process | Flowering, Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Cyclic dof factor 2Alternative name(s): Dof zinc finger protein DOF5.2 Short name: AtDOF5.2 |
Gene namesi | Name:CDF2 Synonyms:DOF5.2 Ordered Locus Names:At5g39660 ORF Names:MIJ24.16 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G39660 |
TAIRi | locus:2164860, AT5G39660 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
Early flowering.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000074292 | 1 – 457 | Cyclic dof factor 2Add BLAST | 457 |
Proteomic databases
PaxDbi | Q93ZL5 |
ProteomicsDBi | 223969 |
Expressioni
Tissue specificityi
Expressed in the vasculature of cotyledons and hypocotyls, leaves and roots.1 Publication
Inductioni
Circadian-regulation. Highly expressed at the beginning of the light period, then decreases, reaching a minimum between 16 and 29 hours after dawn before rising again at the end of the day. Regulated at the protein level by ADO3 and GI pos-transcriptionally.1 Publication
Gene expression databases
ExpressionAtlasi | Q93ZL5, baseline and differential |
Genevisiblei | Q93ZL5, AT |
Interactioni
Subunit structurei
Interacts with ADO2 (via kelch repeats) and ADO3 (via kelch repeats).
1 PublicationBinary interactionsi
Hide detailsQ93ZL5
With | #Exp. | IntAct |
---|---|---|
ADO2 [Q8W420] | 3 | EBI-1536103,EBI-1015688 |
ADO3 [Q9C9W9] | 2 | EBI-1536103,EBI-401228 |
TCP9 [O64647] | 3 | EBI-1536103,EBI-9838721 |
Protein-protein interaction databases
BioGRIDi | 19213, 16 interactors |
IntActi | Q93ZL5, 15 interactors |
STRINGi | 3702.AT5G39660.1 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 281 – 346 | Pro-richAdd BLAST | 66 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 138 – 192 | Dof-typePROSITE-ProRule annotationAdd BLAST | 55 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | ENOG502QSI8, Eukaryota |
HOGENOMi | CLU_030533_1_0_1 |
InParanoidi | Q93ZL5 |
OMAi | SEMQTAP |
OrthoDBi | 853832at2759 |
PhylomeDBi | Q93ZL5 |
Family and domain databases
InterProi | View protein in InterPro IPR003851, Znf_Dof |
Pfami | View protein in Pfam PF02701, zf-Dof, 1 hit |
PROSITEi | View protein in PROSITE PS01361, ZF_DOF_1, 1 hit PS50884, ZF_DOF_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q93ZL5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADPAIKLFG KTIPLPELGV VDSSSSYTGF LTETQIPVRL SDSCTGDDDD
60 70 80 90 100
EEMGDSGLGR EEGDDVGDGG GESETDKKEE KDSECQEESL RNESNDVTTT
110 120 130 140 150
TSGITEKTET TKAAKTNEES GGTACSQEGK LKKPDKILPC PRCNSMETKF
160 170 180 190 200
CYYNNYNVNQ PRHFCKKCQR YWTAGGTMRN VPVGAGRRKN KSPASHYNRH
210 220 230 240 250
VSITSAEAMQ KVARTDLQHP NGANLLTFGS DSVLCESMAS GLNLVEKSLL
260 270 280 290 300
KTQTVLQEPN EGLKITVPLN QTNEEAGTVS PLPKVPCFPG PPPTWPYAWN
310 320 330 340 350
GVSWTILPFY PPPAYWSCPG VSPGAWNSFT WMPQPNSPSG SNPNSPTLGK
360 370 380 390 400
HSRDENAAEP GTAFDETESL GREKSKPERC LWVPKTLRID DPEEAAKSSI
410 420 430 440 450
WETLGIKKDE NADTFGAFRS STKEKSSLSE GRLPGRRPEL QANPAALSRS
ANFHESS
Sequence cautioni
The sequence BAB08898 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 277 | G → R in AAL10495 (PubMed:14593172).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012243 Genomic DNA Translation: BAB08898.1 Sequence problems. CP002688 Genomic DNA Translation: AED94460.1 CP002688 Genomic DNA Translation: AED94461.1 CP002688 Genomic DNA Translation: ANM69712.1 AY056804 mRNA Translation: AAL10495.1 BT015791 mRNA Translation: AAU90081.1 |
RefSeqi | NP_001318708.1, NM_001344299.1 NP_568567.1, NM_123328.2 NP_851106.1, NM_180775.3 |
Genome annotation databases
EnsemblPlantsi | AT5G39660.1; AT5G39660.1; AT5G39660 AT5G39660.2; AT5G39660.2; AT5G39660 AT5G39660.3; AT5G39660.3; AT5G39660 |
GeneIDi | 833962 |
Gramenei | AT5G39660.1; AT5G39660.1; AT5G39660 AT5G39660.2; AT5G39660.2; AT5G39660 AT5G39660.3; AT5G39660.3; AT5G39660 |
KEGGi | ath:AT5G39660 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012243 Genomic DNA Translation: BAB08898.1 Sequence problems. CP002688 Genomic DNA Translation: AED94460.1 CP002688 Genomic DNA Translation: AED94461.1 CP002688 Genomic DNA Translation: ANM69712.1 AY056804 mRNA Translation: AAL10495.1 BT015791 mRNA Translation: AAU90081.1 |
RefSeqi | NP_001318708.1, NM_001344299.1 NP_568567.1, NM_123328.2 NP_851106.1, NM_180775.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 19213, 16 interactors |
IntActi | Q93ZL5, 15 interactors |
STRINGi | 3702.AT5G39660.1 |
Proteomic databases
PaxDbi | Q93ZL5 |
ProteomicsDBi | 223969 |
Genome annotation databases
EnsemblPlantsi | AT5G39660.1; AT5G39660.1; AT5G39660 AT5G39660.2; AT5G39660.2; AT5G39660 AT5G39660.3; AT5G39660.3; AT5G39660 |
GeneIDi | 833962 |
Gramenei | AT5G39660.1; AT5G39660.1; AT5G39660 AT5G39660.2; AT5G39660.2; AT5G39660 AT5G39660.3; AT5G39660.3; AT5G39660 |
KEGGi | ath:AT5G39660 |
Organism-specific databases
Araporti | AT5G39660 |
TAIRi | locus:2164860, AT5G39660 |
Phylogenomic databases
eggNOGi | ENOG502QSI8, Eukaryota |
HOGENOMi | CLU_030533_1_0_1 |
InParanoidi | Q93ZL5 |
OMAi | SEMQTAP |
OrthoDBi | 853832at2759 |
PhylomeDBi | Q93ZL5 |
Miscellaneous databases
PROi | PR:Q93ZL5 |
Gene expression databases
ExpressionAtlasi | Q93ZL5, baseline and differential |
Genevisiblei | Q93ZL5, AT |
Family and domain databases
InterProi | View protein in InterPro IPR003851, Znf_Dof |
Pfami | View protein in Pfam PF02701, zf-Dof, 1 hit |
PROSITEi | View protein in PROSITE PS01361, ZF_DOF_1, 1 hit PS50884, ZF_DOF_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CDF2_ARATH | |
Accessioni | Q93ZL5Primary (citable) accession number: Q93ZL5 Secondary accession number(s): Q5XF25, Q9FK95 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 9, 2004 |
Last sequence update: | November 9, 2004 | |
Last modified: | February 10, 2021 | |
This is version 122 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names