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Entry version 107 (29 Sep 2021)
Sequence version 1 (01 Dec 2001)
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Protein

Magnesium transporter MRS2-4

Gene

MRS2-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Magnesium transporter that may mediate the influx of magnesium.

By similarity

Miscellaneous

Has the ability to complement a mutant in yeast lacking magnesium transport capability.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • magnesium ion transport Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transport
LigandMagnesium

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
7.2.2.14, 399

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.35.5.4, the cora metal ion transporter (mit) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Magnesium transporter MRS2-4
Alternative name(s):
Magnesium Transporter 6
Short name:
AtMGT6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRS2-4
Synonyms:MGT6
Ordered Locus Names:At3g58970
ORF Names:F17J16.20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT3G58970

The Arabidopsis Information Resource

More...
TAIRi
locus:2077665, AT3G58970

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei372 – 392HelicalSequence analysisAdd BLAST21
Transmembranei405 – 425HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003941681 – 436Magnesium transporter MRS2-4Add BLAST436

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q93ZD7

PRoteomics IDEntifications database

More...
PRIDEi
Q93ZD7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
238911

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the whole plant except roots.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q93ZD7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q93ZD7, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
10381, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q93ZD7, 6 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT3G58970.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q93ZD7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 56DisorderedSequence analysisAdd BLAST56

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi392 – 394Required for magnesium transport activity3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2662, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_034694_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q93ZD7

Identification of Orthologs from Complete Genome Data

More...
OMAi
SSGCFMI

Database of Orthologous Groups

More...
OrthoDBi
1363588at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q93ZD7

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12823, Mrs2_Mfm1p-like, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002523, MgTranspt_CorA/ZnTranspt_ZntB
IPR039204, MRS2-like

The PANTHER Classification System

More...
PANTHERi
PTHR13890, PTHR13890, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01544, CorA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q93ZD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKGPLSFRR LSSIRHRKKG SAVKDDSAQT STPSSPPPPL PIHAGGSAVG
60 70 80 90 100
ATGKAKKKTG GARLWMRFDR TGAMEVVECD KSTIIKRASV PARDLRILGP
110 120 130 140 150
VFSHSSNILA REKAIVVNLE VIKAIVTAEE VLLLDPLRPE VLPFVERLKQ
160 170 180 190 200
QFPQRNGNEN ALQASANVQS PLDPEAAEGL QSELPFEFQV LEIALEVVCS
210 220 230 240 250
FVDKSVAALE TEAWPVLDEL TKNVSTENLE YVRSLKSNLT RLLARVQKVR
260 270 280 290 300
DELEHLLDDN EDMADLYLTR KWIQNQQTEA ILAGTASNSI ALPAHNTSNL
310 320 330 340 350
HRLTSNRSAS MVTSNTEEDD VEDLEMLLEA YFMQLDGMRN KILTVREYID
360 370 380 390 400
DTEDYVNIQL DNQRNELIQL QLTLTIASFA IAAETLLASL FGMNIPCPLY
410 420 430
SIHGVFGYFV WSVTALCIVL FMVTLGYARW KKLLGS
Length:436
Mass (Da):48,404
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9EF73B60CA539AF
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB86925 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY150289 mRNA Translation: AAN73214.1
AL163527 Genomic DNA Translation: CAB86925.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE79855.1
AY057613 mRNA Translation: AAL14408.1
BT002266 mRNA Translation: AAN72277.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T47779

NCBI Reference Sequences

More...
RefSeqi
NP_567076.1, NM_115759.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT3G58970.1; AT3G58970.1; AT3G58970

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
825066

Gramene; a comparative resource for plants

More...
Gramenei
AT3G58970.1; AT3G58970.1; AT3G58970

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT3G58970

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY150289 mRNA Translation: AAN73214.1
AL163527 Genomic DNA Translation: CAB86925.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE79855.1
AY057613 mRNA Translation: AAL14408.1
BT002266 mRNA Translation: AAN72277.1
PIRiT47779
RefSeqiNP_567076.1, NM_115759.4

3D structure databases

SMRiQ93ZD7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi10381, 6 interactors
IntActiQ93ZD7, 6 interactors
STRINGi3702.AT3G58970.1

Protein family/group databases

TCDBi1.A.35.5.4, the cora metal ion transporter (mit) family

Proteomic databases

PaxDbiQ93ZD7
PRIDEiQ93ZD7
ProteomicsDBi238911

Genome annotation databases

EnsemblPlantsiAT3G58970.1; AT3G58970.1; AT3G58970
GeneIDi825066
GrameneiAT3G58970.1; AT3G58970.1; AT3G58970
KEGGiath:AT3G58970

Organism-specific databases

AraportiAT3G58970
TAIRilocus:2077665, AT3G58970

Phylogenomic databases

eggNOGiKOG2662, Eukaryota
HOGENOMiCLU_034694_1_0_1
InParanoidiQ93ZD7
OMAiSSGCFMI
OrthoDBi1363588at2759
PhylomeDBiQ93ZD7

Enzyme and pathway databases

BRENDAi7.2.2.14, 399

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q93ZD7

Gene expression databases

ExpressionAtlasiQ93ZD7, baseline and differential
GenevisibleiQ93ZD7, AT

Family and domain databases

CDDicd12823, Mrs2_Mfm1p-like, 1 hit
InterProiView protein in InterPro
IPR002523, MgTranspt_CorA/ZnTranspt_ZntB
IPR039204, MRS2-like
PANTHERiPTHR13890, PTHR13890, 1 hit
PfamiView protein in Pfam
PF01544, CorA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMRS24_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q93ZD7
Secondary accession number(s): Q9LYT9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: December 1, 2001
Last modified: September 29, 2021
This is version 107 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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