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UniProtKB - Q93XX4 (C2D61_ARATH)
Protein
C2 domain-containing protein At1g53590
Gene
NTMC2T6.1
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Cofactori
Ca2+PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 298 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 298 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 304 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 352 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 352 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 354 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 354 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 359 | Calcium 2PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- lipid binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- lipid transport Source: UniProtKB-KW
Keywordsi
Biological process | Lipid transport, Transport |
Ligand | Calcium, Lipid-binding, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: C2 domain-containing protein At1g53590Alternative name(s): N-terminal-TM-C2 domain type 6 protein 1 Short name: NTMC2TYPE6.1 |
Gene namesi | Name:NTMC2T6.1 Ordered Locus Names:At1g53590 ORF Names:F22G10.28, T3F20.10 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G53590 |
TAIRi | locus:2024912, AT1G53590 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Vacuole
- plant-type vacuole Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 2 – 22 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 26 – 46 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000315404 | 1 – 751 | C2 domain-containing protein At1g53590Add BLAST | 751 |
Proteomic databases
PaxDbi | Q93XX4 |
PRIDEi | Q93XX4 |
ProteomicsDBi | 222824 |
PTM databases
iPTMneti | Q93XX4 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q93XX4, baseline and differential |
Genevisiblei | Q93XX4, AT |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 68 – 262 | SMP-LTDPROSITE-ProRule annotationAdd BLAST | 195 | |
Domaini | 267 – 381 | C2PROSITE-ProRule annotationAdd BLAST | 115 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 469 – 519 | DisorderedSequence analysisAdd BLAST | 51 | |
Regioni | 572 – 751 | DisorderedSequence analysisAdd BLAST | 180 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 701 – 728 | Sequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 472 – 486 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 487 – 511 | Polar residuesSequence analysisAdd BLAST | 25 | |
Compositional biasi | 582 – 638 | Basic and acidic residuesSequence analysisAdd BLAST | 57 | |
Compositional biasi | 666 – 685 | Basic and acidic residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 692 – 751 | Basic and acidic residuesSequence analysisAdd BLAST | 60 |
Sequence similaritiesi
Belongs to the extended synaptotagmin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1012, Eukaryota |
HOGENOMi | CLU_017566_0_0_1 |
InParanoidi | Q93XX4 |
OMAi | WTVKDIA |
OrthoDBi | 524702at2759 |
Family and domain databases
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR031468, SMP_LBD |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
SUPFAMi | SSF49562, SSF49562, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit PS51847, SMP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q93XX4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESSLIHHII IVLLLLWFIS SLNRSHAFFY FLALIYLYLV HERYVMRLKR
60 70 80 90 100
KLQFEERKQA NQRRVLSDSE SVRWMNYAVE KIWPICMEQI ASQKILGPII
110 120 130 140 150
PWFLEKYRPW TAKKAVIQHL YMGRNPPLLT DIRVLRQSTG DDHLVLELGM
160 170 180 190 200
NFLAADDMSA ILAVKLRKRL GFGMWTKLHL TGMHVEGKVL IGVKFLRRWP
210 220 230 240 250
FLGRLRVCFA EPPYFQMTVK PIFTHGLDVA VLPGIAGWLD KLLSIAFEQT
260 270 280 290 300
LVQPNMLVVD MEKFVSPTSE NWFFVDEKEP VAHVLVEVFE ASDLKPSDLN
310 320 330 340 350
GLADPYVKGK LGAYRFKTKI QKKTLSPKWH EEFKIPIFTW DSPSILNIEV
360 370 380 390 400
GDKDRFVDDT LGECSVNIEE FRGGQRNDMW LSLQNIKMGR LHLAITVIED
410 420 430 440 450
NAKSSDDPLK KAKLNKEDIQ TSFASDTTNL GSFSSDKSPS VVDNFEPIKI
460 470 480 490 500
DGQEETAIWV QKPGAEVSQI WEPRKGKSRR LDSQIQRTPN DESLSNGSSS
510 520 530 540 550
TDDNQEGSKN PMKSVGRGLR KIGSMFHRNV KKEEFLIGSI EEESQSQSPR
560 570 580 590 600
INLKAVNQKD VGLNFIVDDN LSGPLSGKSL DGESLDAEEN SGKGHMKDVA
610 620 630 640 650
KSFLKQAEKS AKQIKHAFSR KGSMKPRDGH KEIVPESDSG TDSESSDDDD
660 670 680 690 700
AFTCVKNLAT EPGKLTRDGN IERTGDDDHV DSTTLATAKE DSSGDILEDS
710 720 730 740 750
TDVEAKEEKL KEAAESETRD MDTAMNIKTE DEKGDTLKNI EEGEEKESSS
K
Sequence cautioni
The sequence AAF78431 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG51985 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 201 | F → Y in AAK96876 (PubMed:14593172).Curated | 1 | |
Sequence conflicti | 654 | C → Y in AAK96876 (PubMed:14593172).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018748 Genomic DNA Translation: AAF78431.1 Sequence problems. AC024260 Genomic DNA Translation: AAG51985.1 Sequence problems. CP002684 Genomic DNA Translation: AEE32967.1 AY054685 mRNA Translation: AAK96876.1 |
PIRi | A96576 |
RefSeqi | NP_564637.1, NM_104237.4 |
Genome annotation databases
EnsemblPlantsi | AT1G53590.1; AT1G53590.1; AT1G53590 |
GeneIDi | 841794 |
Gramenei | AT1G53590.1; AT1G53590.1; AT1G53590 |
KEGGi | ath:AT1G53590 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC018748 Genomic DNA Translation: AAF78431.1 Sequence problems. AC024260 Genomic DNA Translation: AAG51985.1 Sequence problems. CP002684 Genomic DNA Translation: AEE32967.1 AY054685 mRNA Translation: AAK96876.1 |
PIRi | A96576 |
RefSeqi | NP_564637.1, NM_104237.4 |
3D structure databases
SMRi | Q93XX4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT1G53590.1 |
PTM databases
iPTMneti | Q93XX4 |
Proteomic databases
PaxDbi | Q93XX4 |
PRIDEi | Q93XX4 |
ProteomicsDBi | 222824 |
Genome annotation databases
EnsemblPlantsi | AT1G53590.1; AT1G53590.1; AT1G53590 |
GeneIDi | 841794 |
Gramenei | AT1G53590.1; AT1G53590.1; AT1G53590 |
KEGGi | ath:AT1G53590 |
Organism-specific databases
Araporti | AT1G53590 |
TAIRi | locus:2024912, AT1G53590 |
Phylogenomic databases
eggNOGi | KOG1012, Eukaryota |
HOGENOMi | CLU_017566_0_0_1 |
InParanoidi | Q93XX4 |
OMAi | WTVKDIA |
OrthoDBi | 524702at2759 |
Miscellaneous databases
PROi | PR:Q93XX4 |
Gene expression databases
ExpressionAtlasi | Q93XX4, baseline and differential |
Genevisiblei | Q93XX4, AT |
Family and domain databases
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR031468, SMP_LBD |
Pfami | View protein in Pfam PF00168, C2, 1 hit |
SMARTi | View protein in SMART SM00239, C2, 1 hit |
SUPFAMi | SSF49562, SSF49562, 1 hit |
PROSITEi | View protein in PROSITE PS50004, C2, 1 hit PS51847, SMP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | C2D61_ARATH | |
Accessioni | Q93XX4Primary (citable) accession number: Q93XX4 Secondary accession number(s): Q9C8L5, Q9LPH4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | May 3, 2011 | |
Last modified: | February 23, 2022 | |
This is version 106 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families