UniProtKB - Q93WK5 (APRR7_ARATH)
Two-component response regulator-like APRR7
APRR7
Functioni
Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Represses the expression of other clock proteins and master regulators of plant growth, development and response to abiotic stress. Involved in the positive and negative feedback loops of the circadian clock. Controls photoperiodic flowering response and temperature compensation. Expression of several members of the ARR-like family is controlled by circadian rhythm. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes to repress their expression from noon until midnight. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock.
8 PublicationsMiscellaneous
Caution
GO - Molecular functioni
- DNA binding Source: TAIR
GO - Biological processi
- circadian rhythm Source: TAIR
- cytokinin-activated signaling pathway Source: InterPro
- negative regulation of transcription, DNA-templated Source: TAIR
- phosphorelay signal transduction system Source: UniProtKB-KW
- red or far-red light signaling pathway Source: TAIR
- regulation of transcription, DNA-templated Source: TAIR
Keywordsi
Biological process | Biological rhythms, Transcription, Transcription regulation, Two-component regulatory system |
Names & Taxonomyi
Protein namesi | Recommended name: Two-component response regulator-like APRR7Alternative name(s): Pseudo-response regulator 7 |
Gene namesi | Name:APRR7 Ordered Locus Names:At5g02810 ORF Names:F9G14_120 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G02810 |
TAIRi | locus:2151206, AT5G02810 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation1 Publication
Mitochondrion
- mitochondrion Source: TAIR
Nucleus
- nucleus Source: TAIR
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000081439 | 1 – 727 | Two-component response regulator-like APRR7Add BLAST | 727 |
Post-translational modificationi
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q93WK5 |
PRIDEi | Q93WK5 |
ProteomicsDBi | 244462 |
PTM databases
iPTMneti | Q93WK5 |
Expressioni
Inductioni
Gene expression databases
ExpressionAtlasi | Q93WK5, baseline and differential |
Genevisiblei | Q93WK5, AT |
Interactioni
Binary interactionsi
Q93WK5
With | #Exp. | IntAct |
---|---|---|
PYL8 [Q9FGM1] | 3 | EBI-25528701,EBI-2429535 |
Protein-protein interaction databases
BioGRIDi | 17069, 11 interactors |
IntActi | Q93WK5, 1 interactor |
STRINGi | 3702.AT5G02810.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 79 – 197 | Response regulatoryPROSITE-ProRule annotationAdd BLAST | 119 | |
Domaini | 669 – 711 | CCTPROSITE-ProRule annotationAdd BLAST | 43 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 47 | DisorderedSequence analysisAdd BLAST | 47 | |
Regioni | 203 – 265 | DisorderedSequence analysisAdd BLAST | 63 | |
Regioni | 291 – 312 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 339 – 416 | DisorderedSequence analysisAdd BLAST | 78 | |
Regioni | 464 – 487 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 509 – 560 | DisorderedSequence analysisAdd BLAST | 52 | |
Regioni | 606 – 670 | DisorderedSequence analysisAdd BLAST | 65 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 10 – 43 | Basic and acidic residuesSequence analysisAdd BLAST | 34 | |
Compositional biasi | 203 – 218 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 234 – 264 | Polar residuesSequence analysisAdd BLAST | 31 | |
Compositional biasi | 606 – 664 | Polar residuesSequence analysisAdd BLAST | 59 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG1601, Eukaryota |
HOGENOMi | CLU_015512_1_0_1 |
InParanoidi | Q93WK5 |
OMAi | PPNQCSN |
OrthoDBi | 320146at2759 |
PhylomeDBi | Q93WK5 |
Family and domain databases
InterProi | View protein in InterPro IPR045279, ARR-like IPR010402, CCT_domain IPR011006, CheY-like_superfamily IPR001789, Sig_transdc_resp-reg_receiver |
PANTHERi | PTHR43874, PTHR43874, 2 hits |
Pfami | View protein in Pfam PF06203, CCT, 1 hit PF00072, Response_reg, 1 hit |
SMARTi | View protein in SMART SM00448, REC, 1 hit |
SUPFAMi | SSF52172, SSF52172, 1 hit |
PROSITEi | View protein in PROSITE PS51017, CCT, 1 hit PS50110, RESPONSE_REGULATORY, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MNANEEGEGS RYPITDRKTG ETKFDRVESR TEKHSEEEKT NGITMDVRNG
60 70 80 90 100
SSGGLQIPLS QQTAATVCWE RFLHVRTIRV LLVENDDCTR YIVTALLRNC
110 120 130 140 150
SYEVVEASNG IQAWKVLEDL NNHIDIVLTE VIMPYLSGIG LLCKILNHKS
160 170 180 190 200
RRNIPVIMMS SHDSMGLVFK CLSKGAVDFL VKPIRKNELK ILWQHVWRRC
210 220 230 240 250
QSSSGSGSES GTHQTQKSVK SKSIKKSDQD SGSSDENENG SIGLNASDGS
260 270 280 290 300
SDGSGAQSSW TKKAVDVDDS PRAVSLWDRV DSTCAQVVHS NPEFPSNQLV
310 320 330 340 350
APPAEKETQE HDDKFEDVTM GRDLEISIRR NCDLALEPKD EPLSKTTGIM
360 370 380 390 400
RQDNSFEKSS SKWKMKVGKG PLDLSSESPS SKQMHEDGGS SFKAMSSHLQ
410 420 430 440 450
DNREPEAPNT HLKTLDTNEA SVKISEELMH VEHSSKRHRG TKDDGTLVRD
460 470 480 490 500
DRNVLRRSEG SAFSRYNPAS NANKISGGNL GSTSLQDNNS QDLIKKTEAA
510 520 530 540 550
YDCHSNMNES LPHNHRSHVG SNNFDMSSTT ENNAFTKPGA PKVSSAGSSS
560 570 580 590 600
VKHSSFQPLP CDHHNNHASY NLVHVAERKK LPPQCGSSNV YNETIEGNNN
610 620 630 640 650
TVNYSVNGSV SGSGHGSNGP YGSSNGMNAG GMNMGSDNGA GKNGNGDGSG
660 670 680 690 700
SGSGSGSGNL ADENKISQRE AALTKFRQKR KERCFRKKVR YQSRKKLAEQ
710 720
RPRVRGQFVR KTAAATDDND IKNIEDS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8BCB0 | A0A1P8BCB0_ARATH | Pseudo-response regulator 7 | PRR7 APRR7, pseudo-response regulator 7, At5g02810, F9G14.120, F9G14_120 | 583 | Annotation score: |
Sequence cautioni
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB046954 mRNA Translation: BAB13742.1 AL162973 Genomic DNA Translation: CAB86035.1 Sequence problems. CP002688 Genomic DNA Translation: AED90520.1 AY039943 mRNA Translation: AAK64047.1 AY142560 mRNA Translation: AAN13129.1 |
PIRi | T48302 |
RefSeqi | NP_568107.1, NM_120359.3 |
Genome annotation databases
EnsemblPlantsi | AT5G02810.1; AT5G02810.1; AT5G02810 |
GeneIDi | 831793 |
Gramenei | AT5G02810.1; AT5G02810.1; AT5G02810 |
KEGGi | ath:AT5G02810 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB046954 mRNA Translation: BAB13742.1 AL162973 Genomic DNA Translation: CAB86035.1 Sequence problems. CP002688 Genomic DNA Translation: AED90520.1 AY039943 mRNA Translation: AAK64047.1 AY142560 mRNA Translation: AAN13129.1 |
PIRi | T48302 |
RefSeqi | NP_568107.1, NM_120359.3 |
3D structure databases
AlphaFoldDBi | Q93WK5 |
SMRi | Q93WK5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 17069, 11 interactors |
IntActi | Q93WK5, 1 interactor |
STRINGi | 3702.AT5G02810.1 |
PTM databases
iPTMneti | Q93WK5 |
Proteomic databases
PaxDbi | Q93WK5 |
PRIDEi | Q93WK5 |
ProteomicsDBi | 244462 |
Genome annotation databases
EnsemblPlantsi | AT5G02810.1; AT5G02810.1; AT5G02810 |
GeneIDi | 831793 |
Gramenei | AT5G02810.1; AT5G02810.1; AT5G02810 |
KEGGi | ath:AT5G02810 |
Organism-specific databases
Araporti | AT5G02810 |
TAIRi | locus:2151206, AT5G02810 |
Phylogenomic databases
eggNOGi | KOG1601, Eukaryota |
HOGENOMi | CLU_015512_1_0_1 |
InParanoidi | Q93WK5 |
OMAi | PPNQCSN |
OrthoDBi | 320146at2759 |
PhylomeDBi | Q93WK5 |
Miscellaneous databases
PROi | PR:Q93WK5 |
Gene expression databases
ExpressionAtlasi | Q93WK5, baseline and differential |
Genevisiblei | Q93WK5, AT |
Family and domain databases
InterProi | View protein in InterPro IPR045279, ARR-like IPR010402, CCT_domain IPR011006, CheY-like_superfamily IPR001789, Sig_transdc_resp-reg_receiver |
PANTHERi | PTHR43874, PTHR43874, 2 hits |
Pfami | View protein in Pfam PF06203, CCT, 1 hit PF00072, Response_reg, 1 hit |
SMARTi | View protein in SMART SM00448, REC, 1 hit |
SUPFAMi | SSF52172, SSF52172, 1 hit |
PROSITEi | View protein in PROSITE PS51017, CCT, 1 hit PS50110, RESPONSE_REGULATORY, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | APRR7_ARATH | |
Accessioni | Q93WK5Primary (citable) accession number: Q93WK5 Secondary accession number(s): Q9LZ04 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 27, 2004 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families