Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peroxidase 44

Gene

PER44

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Removal of H2O2, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.

Miscellaneous

There are 73 peroxidase genes in A.thaliana.

Catalytic activityi

2 phenolic donor + H2O2 = 2 phenoxyl radical of the donor + 2 H2O.

Cofactori

Protein has several cofactor binding sites:
  • heme bPROSITE-ProRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.PROSITE-ProRule annotation
  • Ca2+PROSITE-ProRule annotationNote: Binds 2 calcium ions per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei58Transition state stabilizerPROSITE-ProRule annotation1
Active sitei62Proton acceptorPROSITE-ProRule annotation1
Metal bindingi63Calcium 1PROSITE-ProRule annotation1
Metal bindingi66Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi68Calcium 1; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi70Calcium 1PROSITE-ProRule annotation1
Metal bindingi72Calcium 1PROSITE-ProRule annotation1
Binding sitei156Substrate; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi187Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi188Calcium 2PROSITE-ProRule annotation1
Metal bindingi229Calcium 2PROSITE-ProRule annotation1
Metal bindingi232Calcium 2PROSITE-ProRule annotation1
Metal bindingi237Calcium 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandCalcium, Heme, Iron, Metal-binding

Protein family/group databases

PeroxiBasei210 AtPrx44

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxidase 44 (EC:1.11.1.7)
Short name:
Atperox P44
Alternative name(s):
ATP35
Gene namesi
Name:PER44
Synonyms:P44
Ordered Locus Names:At4g26010
ORF Names:F20B18.120
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G26010
TAIRilocus:2120760 AT4G26010

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000002371021 – 310Peroxidase 44Add BLAST290

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi31 ↔ 110PROSITE-ProRule annotation
Disulfide bondi64 ↔ 69PROSITE-ProRule annotation
Disulfide bondi116 ↔ 305PROSITE-ProRule annotation
Disulfide bondi194 ↔ 218PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ93V93
PRIDEiQ93V93

Expressioni

Gene expression databases

ExpressionAtlasiQ93V93 baseline and differential
GenevisibleiQ93V93 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G26010.1

Structurei

3D structure databases

ProteinModelPortaliQ93V93
SMRiQ93V93
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IEWY Eukaryota
ENOG4110UVG LUCA
HOGENOMiHOG000237556
InParanoidiQ93V93
KOiK00430
OMAiQWSALKL
OrthoDBiEOG09360MRF
PhylomeDBiQ93V93

Family and domain databases

CDDicd00693 secretory_peroxidase, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR000823 Peroxidase_pln
IPR019794 Peroxidases_AS
IPR033905 Secretory_peroxidase
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00458 PEROXIDASE
PR00461 PLPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q93V93-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSITALFFL FCFLAPSALA QLRTGFYSRS CPRAESIVAS VVANRFRSDK
60 70 80 90 100
SITAAFLRMQ FHDCFVRGCD ASLLIDPRPG RPSEKSTGPN ASVRGYEIID
110 120 130 140 150
EAKRQLEAAC PRTVSCADIV TLATRDSVAL AGGPRFSVPT GRRDGLRSNP
160 170 180 190 200
NDVNLPGPTI PVSASIQLFA AQGMNTNDMV TLIGGGHSVG VAHCSLFQDR
210 220 230 240 250
LSDRAMEPSL KSSLRRKCSS PNDPTTFLDQ KTSFTVDNAI YGEIRRQRGI
260 270 280 290 300
LRIDQNLGLD RSTSGIVSGY ASSNTLFRKR FAEALVKMGT IKVLTGRSGE
310
IRRNCRVFNN
Length:310
Mass (Da):33,806
Last modified:December 1, 2001 - v1
Checksum:iE14CEB2BA47B5550
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8B428A0A1P8B428_ARATH
Peroxidase
At4g26010, F20B18.120, F20B18_120
338Annotation score:

Sequence cautioni

The sequence CAB39666 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79456 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF452386 mRNA Translation: AAL40850.1
AL049483 Genomic DNA Translation: CAB39666.1 Sequence problems.
AL161564 Genomic DNA Translation: CAB79456.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE85144.1
AF412066 mRNA Translation: AAL06519.1
AF428430 mRNA Translation: AAL16199.1
AY090260 mRNA Translation: AAL90921.1
PIRiT04256
RefSeqiNP_567738.1, NM_118734.2
UniGeneiAt.2955

Genome annotation databases

EnsemblPlantsiAT4G26010.1; AT4G26010.1; AT4G26010
GeneIDi828707
GrameneiAT4G26010.1; AT4G26010.1; AT4G26010
KEGGiath:AT4G26010

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF452386 mRNA Translation: AAL40850.1
AL049483 Genomic DNA Translation: CAB39666.1 Sequence problems.
AL161564 Genomic DNA Translation: CAB79456.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE85144.1
AF412066 mRNA Translation: AAL06519.1
AF428430 mRNA Translation: AAL16199.1
AY090260 mRNA Translation: AAL90921.1
PIRiT04256
RefSeqiNP_567738.1, NM_118734.2
UniGeneiAt.2955

3D structure databases

ProteinModelPortaliQ93V93
SMRiQ93V93
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G26010.1

Protein family/group databases

PeroxiBasei210 AtPrx44

Proteomic databases

PaxDbiQ93V93
PRIDEiQ93V93

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G26010.1; AT4G26010.1; AT4G26010
GeneIDi828707
GrameneiAT4G26010.1; AT4G26010.1; AT4G26010
KEGGiath:AT4G26010

Organism-specific databases

AraportiAT4G26010
TAIRilocus:2120760 AT4G26010

Phylogenomic databases

eggNOGiENOG410IEWY Eukaryota
ENOG4110UVG LUCA
HOGENOMiHOG000237556
InParanoidiQ93V93
KOiK00430
OMAiQWSALKL
OrthoDBiEOG09360MRF
PhylomeDBiQ93V93

Miscellaneous databases

PROiPR:Q93V93

Gene expression databases

ExpressionAtlasiQ93V93 baseline and differential
GenevisibleiQ93V93 AT

Family and domain databases

CDDicd00693 secretory_peroxidase, 1 hit
InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR000823 Peroxidase_pln
IPR019794 Peroxidases_AS
IPR033905 Secretory_peroxidase
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00458 PEROXIDASE
PR00461 PLPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPER44_ARATH
AccessioniPrimary (citable) accession number: Q93V93
Secondary accession number(s): Q9SZH5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: December 1, 2001
Last modified: October 10, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again