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Entry version 92 (31 Jul 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Probable protein phosphatase 2C 62

Gene

At4g33500

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi514Manganese 1By similarity1
Metal bindingi514Manganese 2By similarity1
Metal bindingi515Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi643Manganese 2By similarity1
Metal bindingi710Manganese 2By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable protein phosphatase 2C 62 (EC:3.1.3.16)
Short name:
AtPP2C62
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At4g33500
ORF Names:F17M5.260
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G33500

The Arabidopsis Information Resource

More...
TAIRi
locus:2119246 AT4G33500

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003679841 – 724Probable protein phosphatase 2C 62Add BLAST724

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q93V88

PRoteomics IDEntifications database

More...
PRIDEi
Q93V88

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q93V88

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q93V88 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q93V88 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT4G33500.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q93V88

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini482 – 719PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST238

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi49 – 61Poly-SerAdd BLAST13

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1379 Eukaryota
COG0631 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115318

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q93V88

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIGIADG

Database of Orthologous Groups

More...
OrthoDBi
826926at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q93V88

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
IPR039123 PPTC7

The PANTHER Classification System

More...
PANTHERi
PTHR12320 PTHR12320, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07228 SpoIIE, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81606 SSF81606, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51746 PPM_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q93V88-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADHLILSLQ APPFLIFPCS LHRSWRFPGG IRYSVPEFRL SSQLQLANSI
60 70 80 90 100
SPSKSSASSS SPPENSAPEK FDLVSSTQLK DGSHVFRFGD ASEIEKYLEA
110 120 130 140 150
EEKARCVEVE TQNAKIAEEA SEVSRKQKKL VSSIIETSTE KEETAAPSDL
160 170 180 190 200
SNVIKIKDRK RVRSPTKKKK ETVNVSRSED KIDAKSASVS NLSSIVSVAE
210 220 230 240 250
AIPISSTEEE AVVEKEITAK SYNVEPLSSE AMKKVSVNKI GDCETNGYQE
260 270 280 290 300
NRMEVQARPS LSTQQEITPV STIEIDDNLD VTEKPIEAEE NLVAEPTATD
310 320 330 340 350
DLSPDELLST SEATHRSVDE IAQKPVIDTS EENLLNTFEA EENPVVEPTA
360 370 380 390 400
TAAVSSDELI STSEATRHSV DEIAQKPIID TSEKNPMETF VEPEAVHSSV
410 420 430 440 450
DESTEKLVVV TSDVENDGEN VASTTEDEIT VRDTITDSGS ISNNDDTKVE
460 470 480 490 500
DLQLPVPETA SLEPIKAASG REELVSKAFY LDSGFASLQS PFKALAGRED
510 520 530 540 550
AYFISHHNWI GIADGVSQWS FEGINKGMYA QELMSNCEKI ISNETAKISD
560 570 580 590 600
PVQVLHRSVN ETKSSGSSTA LIAHLDNNEL HIANIGDSGF MVIRDGTVLQ
610 620 630 640 650
NSSPMFHHFC FPLHITQGCD VLKLAEVYHV NLEEGDVVIA ATDGLFDNLY
660 670 680 690 700
EKEIVSIVCG SLKQSLEPQK IAELVAAKAQ EVGRSKTERT PFADAAKEEG
710 720
YNGHKGGKLD AVTVIISFVK IVST
Length:724
Mass (Da):78,924
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE395C345F5F79D64
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB38808 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80067 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL035678 Genomic DNA Translation: CAB38808.1 Sequence problems.
AL161583 Genomic DNA Translation: CAB80067.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86236.1
AY035047 mRNA Translation: AAK59552.1
AY051052 mRNA Translation: AAK93729.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T06001

NCBI Reference Sequences

More...
RefSeqi
NP_567923.1, NM_119504.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G33500.1; AT4G33500.1; AT4G33500

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
829488

Gramene; a comparative resource for plants

More...
Gramenei
AT4G33500.1; AT4G33500.1; AT4G33500

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G33500

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035678 Genomic DNA Translation: CAB38808.1 Sequence problems.
AL161583 Genomic DNA Translation: CAB80067.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86236.1
AY035047 mRNA Translation: AAK59552.1
AY051052 mRNA Translation: AAK93729.1
PIRiT06001
RefSeqiNP_567923.1, NM_119504.4

3D structure databases

SMRiQ93V88
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G33500.1

PTM databases

iPTMnetiQ93V88

Proteomic databases

PaxDbiQ93V88
PRIDEiQ93V88

Genome annotation databases

EnsemblPlantsiAT4G33500.1; AT4G33500.1; AT4G33500
GeneIDi829488
GrameneiAT4G33500.1; AT4G33500.1; AT4G33500
KEGGiath:AT4G33500

Organism-specific databases

AraportiAT4G33500
TAIRilocus:2119246 AT4G33500

Phylogenomic databases

eggNOGiKOG1379 Eukaryota
COG0631 LUCA
HOGENOMiHOG000115318
InParanoidiQ93V88
OMAiWIGIADG
OrthoDBi826926at2759
PhylomeDBiQ93V88

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q93V88

Gene expression databases

ExpressionAtlasiQ93V88 baseline and differential
GenevisibleiQ93V88 AT

Family and domain databases

Gene3Di3.60.40.10, 2 hits
InterProiView protein in InterPro
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
IPR039123 PPTC7
PANTHERiPTHR12320 PTHR12320, 2 hits
PfamiView protein in Pfam
PF07228 SpoIIE, 1 hit
SMARTiView protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiP2C62_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q93V88
Secondary accession number(s): Q9SZC7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 1, 2001
Last modified: July 31, 2019
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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