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UniProtKB - Q93N33 (Q93N33_AERHY)
Protein
Histidine kinase
Gene
prlS
Organism
Aeromonas hydrophila
Status
Functioni
Catalytic activityi
- ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.ARBA annotation EC:2.7.13.3
GO - Molecular functioni
- phosphorelay sensor kinase activity Source: InterPro
- transmembrane transporter activity Source: InterPro
Protein family/group databases
TCDBi | 2.A.21.9.2, the solute:sodium symporter (sss) family |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:prlSImported |
Organismi | Aeromonas hydrophilaImported |
Taxonomic identifieri | 644 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 25 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 37 – 58 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 70 – 92 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 113 – 138 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 158 – 177 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 189 – 216 | HelicalSequence analysisAdd BLAST | 28 | |
Transmembranei | 236 – 260 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 281 – 301 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 327 – 355 | HelicalSequence analysisAdd BLAST | 29 | |
Transmembranei | 376 – 399 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 411 – 432 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 439 – 464 | HelicalSequence analysisAdd BLAST | 26 |
Keywords - Cellular componenti
MembranePTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1086 | 4-aspartylphosphatePROSITE-ProRule annotation | 1 |
Keywords - PTMi
PhosphoproteinPROSITE-ProRule annotationARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 794 – 1014 | Histidine kinaseInterPro annotationAdd BLAST | 221 | |
Domaini | 1036 – 1152 | Response regulatoryInterPro annotationAdd BLAST | 117 |
Sequence similaritiesi
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationFamily and domain databases
CDDi | cd00082, HisKA, 1 hit cd00130, PAS, 1 hit |
Gene3Di | 1.20.1730.10, 1 hit 3.30.565.10, 1 hit |
InterProi | View protein in InterPro IPR011006, CheY-like_superfamily IPR003594, HATPase_C IPR036890, HATPase_C_sf IPR005467, His_kinase_dom IPR003661, HisK_dim/P IPR036097, HisK_dim/P_sf IPR038377, Na/Glc_symporter_sf IPR001734, Na/solute_symporter IPR000014, PAS IPR035965, PAS-like_dom_sf IPR004358, Sig_transdc_His_kin-like_C IPR001789, Sig_transdc_resp-reg_receiver |
Pfami | View protein in Pfam PF02518, HATPase_c, 1 hit PF00512, HisKA, 1 hit PF00072, Response_reg, 1 hit |
PRINTSi | PR00344, BCTRLSENSOR |
SMARTi | View protein in SMART SM00387, HATPase_c, 1 hit SM00388, HisKA, 1 hit SM00448, REC, 1 hit |
SUPFAMi | SSF47384, SSF47384, 1 hit SSF52172, SSF52172, 1 hit SSF55785, SSF55785, 1 hit SSF55874, SSF55874, 1 hit |
PROSITEi | View protein in PROSITE PS50109, HIS_KIN, 1 hit PS50283, NA_SOLUT_SYMP_3, 1 hit PS50110, RESPONSE_REGULATORY, 1 hit |
i Sequence
Sequence statusi: Complete.
Q93N33-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHQGWLLIGM SLAYLGLLFL IAFVADKSKR RRLKGQPLLY SLSLAVYCTS
60 70 80 90 100
WTFFGTVGQA SESPWSPVPI YLGPMLVFLF GWRLLARLIL VAKREHITSI
110 120 130 140 150
ADFIAARYGK SQRLAMVITL IAVMGILPYL VLQLKAIVTG LDMLMANSVP
160 170 180 190 200
VGPTGNTGGL ALGVTMILAL FSILFGTRNL DATEHHRGMV VAIAFESLVK
210 220 230 240 250
LLAFMAVGGF ALWLIIAKPS QARTLVASDF LDAVVAVSPG SLLELAIYTL
260 270 280 290 300
VAMCAVICLP RQFHVTVVEN NQGQDLHWAR WVFPLYLFLM GLFIWPLALA
310 320 330 340 350
GKQWVGAGMG SDTYVISLPM SLGYDGMAML AFLGGTSAAT GMVIVCTIAL
360 370 380 390 400
AIMVSNDLVL PVLLRRFWQQ GRDERLMRLL LQVRRGAILL ILLAAWALYL
410 420 430 440 450
WLGDLTSLSR IGYLSFGAVA QFAPALLLGL YWRHGNRKGV YLGLSLGVSL
460 470 480 490 500
WFLTLLAESG LLAGSPLEAL LAPPNWPAFR DLSLGAWCIF ISLLLNLVGY
510 520 530 540 550
VAGSLLSRAA VSERLQAANF VGKPSQDQAA LYQARVSVKE LEMLAARFVG
560 570 580 590 600
SSRVKRAFGR FAGEHGGTLA PQMQASADLI AHTERLLAGV FGTSSARLVL
610 620 630 640 650
ASALQGRNMQ LEEIATIVDE ASDVFRFNRG LLQGAIEHMG QGISVVDREL
660 670 680 690 700
KLVAWNRRYI ELFHYPPGLI QVGRSIEEII RYNAEQGLCG PGELEAHVAR
710 720 730 740 750
RVAFMQRGSP HVSARERPDG RVIEMQGNPM PAGGFVMTFT DITPFRAAER
760 770 780 790 800
VLREANEHLE ARVAERTHEL NRQLLLVNQQ VERANHSKSR FLAAVSHDLT
810 820 830 840 850
QPLNAAKLFT SSLLEMLPGV QGAEQRAEQV RIARHIDDAL GATEDLITDL
860 870 880 890 900
LDISRLEAGK FKAKKLDFAL REVFDNLKAE FGVLAQAGDI QFSVVESKLA
910 920 930 940 950
VYSDVRLLRR VLQNFLTNAF RYNPGGRVLL GCRRLGDKVR IEVWDNGPGI
960 970 980 990 1000
PLDKQEAIFD EFSRLDHSRT AREQGLGLGL AIARGISLVL GHPLSLRSWP
1010 1020 1030 1040 1050
QAGSVFSITL NLATRPVMPT QVAAPAVRDS QLEGIKILCI DNEEDILTAM
1060 1070 1080 1090 1100
HSLLGRWGCE VVCAQSLAQA EDLIAGGFLP RLVLSDYHLD DGKTGLQALH
1110 1120 1130 1140 1150
MIRLAHGNEI GGIIISADRK SELQAQIREH GYGYVSKPVK PLKLRALMNS
LLLPIA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF388670 Genomic DNA Translation: AAK71637.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF388670 Genomic DNA Translation: AAK71637.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
TCDBi | 2.A.21.9.2, the solute:sodium symporter (sss) family |
Family and domain databases
CDDi | cd00082, HisKA, 1 hit cd00130, PAS, 1 hit |
Gene3Di | 1.20.1730.10, 1 hit 3.30.565.10, 1 hit |
InterProi | View protein in InterPro IPR011006, CheY-like_superfamily IPR003594, HATPase_C IPR036890, HATPase_C_sf IPR005467, His_kinase_dom IPR003661, HisK_dim/P IPR036097, HisK_dim/P_sf IPR038377, Na/Glc_symporter_sf IPR001734, Na/solute_symporter IPR000014, PAS IPR035965, PAS-like_dom_sf IPR004358, Sig_transdc_His_kin-like_C IPR001789, Sig_transdc_resp-reg_receiver |
Pfami | View protein in Pfam PF02518, HATPase_c, 1 hit PF00512, HisKA, 1 hit PF00072, Response_reg, 1 hit |
PRINTSi | PR00344, BCTRLSENSOR |
SMARTi | View protein in SMART SM00387, HATPase_c, 1 hit SM00388, HisKA, 1 hit SM00448, REC, 1 hit |
SUPFAMi | SSF47384, SSF47384, 1 hit SSF52172, SSF52172, 1 hit SSF55785, SSF55785, 1 hit SSF55874, SSF55874, 1 hit |
PROSITEi | View protein in PROSITE PS50109, HIS_KIN, 1 hit PS50283, NA_SOLUT_SYMP_3, 1 hit PS50110, RESPONSE_REGULATORY, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q93N33_AERHY | |
Accessioni | Q93N33Primary (citable) accession number: Q93N33 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 1, 2001 |
Last sequence update: | December 1, 2001 | |
Last modified: | September 29, 2021 | |
This is version 98 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |