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Entry version 160 (16 Oct 2019)
Sequence version 2 (01 Oct 2002)
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Protein
Submitted name:

Uncharacterized protein

Gene

C11E4.6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:C11E4.6Imported, CELE_C11E4.6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

WormBase

More...
WormBasei
C11E4.6 ; CE31411 ; WBGene00007520

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q93203

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q93203

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
WBGene00007520 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
CELE_R07G3.8Q093873EBI-315294,EBI-325893

Protein-protein interaction databases

Database of interacting proteins

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DIPi
DIP-25879N

Protein interaction database and analysis system

More...
IntActi
Q93203, 10 interactors

Molecular INTeraction database

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MINTi
Q93203

STRING: functional protein association networks

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STRINGi
6239.C11E4.6

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q93203

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini61 – 286ANK_REP_REGIONInterPro annotationAdd BLAST226
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati95 – 116ANKPROSITE-ProRule annotationAdd BLAST22
Repeati133 – 165ANKPROSITE-ProRule annotationAdd BLAST33
Repeati214 – 246ANKPROSITE-ProRule annotationAdd BLAST33
Repeati246 – 278ANKPROSITE-ProRule annotationAdd BLAST33
Domaini911 – 972SAMInterPro annotationAdd BLAST62
Domaini1021 – 1141PIDInterPro annotationAdd BLAST121

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni319 – 396DisorderedSequence analysisAdd BLAST78
Regioni703 – 772DisorderedSequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi319 – 333PolyampholyteSequence analysisAdd BLAST15
Compositional biasi334 – 366PolarSequence analysisAdd BLAST33
Compositional biasi379 – 396PolarSequence analysisAdd BLAST18
Compositional biasi703 – 727PolarSequence analysisAdd BLAST25
Compositional biasi735 – 765PolarSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IQT9 Eukaryota
ENOG4111F95 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000020725

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q93203

KEGG Orthology (KO)

More...
KOi
K21413

Identification of Orthologs from Complete Genome Data

More...
OMAi
QQEDNDP

Database of Orthologous Groups

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OrthoDBi
549581at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q93203

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
1.25.40.20, 2 hits
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 2 hits
PF00640 PID, 1 hit
PF00536 SAM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 5 hits
SM00462 PTB, 1 hit
SM00454 SAM, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769 SSF47769, 1 hit
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS01179 PID, 1 hit
PS50105 SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q93203-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLKDFVISK TEVIDACKKG EYDKVALFLS SKKGKKIRSG LKFFTTRSDS
60 70 80 90 100
HWLADYKDEK SDFTLLHHAV LENQNQISKL LMDYEPLLLL CKSTKNILPI
110 120 130 140 150
HLAAWNGNLE IVKMLLLQTM EKPADILNAV NIFNETPLHL AVQRCHLEVV
160 170 180 190 200
FYLIKKNADP FIRNENKENV IDVASRIGSA EAIRMLCQKW PKFPVQSAYE
210 220 230 240 250
SLRVGTPDIK RPFPAIYPFH LAAKYNHVEC MQALREHGFS INYTTEDGTA
260 270 280 290 300
LHVASACGQA EAVRFLLEIG VNTDIKNQHG QTVLQMIIDL QENRRNEIAH
310 320 330 340 350
FVKNPEGWKE CRTIIEGMDR RDSGRETEGS QSDNEREAIW QPLPSQASVQ
360 370 380 390 400
VYPDQRRNNH SIYQPPSISA RLRDLSPDDS TEALNSVRSE GPYTTHSINR
410 420 430 440 450
TWNSSMLDRA PRTGRFPLTS PSYHSKHYSC QRSSDTLPTR LKNVRTRPTE
460 470 480 490 500
KQIASVLPGD NCAYNSPSKF NEWQKSQLTI SNRPPAPYDN VPNNSAIFVR
510 520 530 540 550
PNSPIARSAS LRRQSGYATL PKLATYSPRI PDHGRPDLND AFIQDPDKTM
560 570 580 590 600
DRSLNRNQFS ISRTTCDREE SLGLTQSPRL DTRASSITSS LTYACSTLDK
610 620 630 640 650
DKFFRERERD NGRAPLAMPE EITGSVTGSV IYSQGNANQH LNGNYEKDNN
660 670 680 690 700
VTAIFLEDVM RPSSNSAESP PSPNTSKAFI FDALCGKSRL VDSTNVDFFS
710 720 730 740 750
GFSSSSNLSH RSTESTSKVQ MNSSFTEPEE PVRIRRQNGT TNLMLNSLSP
760 770 780 790 800
TDNLSSPSSD QKSDTTSEEP SWDRVESVFD SFGAAPCRES VFVREYEPRV
810 820 830 840 850
AVYLRDRGSK ALSVTLVEDE FRDHKSLLVK KQPKTIIEWL ESDVMLAPVA
860 870 880 890 900
ADSVGALLQT HGYDRMDQLK GIINRSILTE IGVDDVTKFK IMSEIEKLKD
910 920 930 940 950
DVASAGRFFY VSEWLNFIGL QDYISNFVGA GYKHMAKLTE IDWDTARLMQ
960 970 980 990 1000
LGVTRPGHIA RMLHSFKKAE DEKRKEYNNR LQIKPLMSPP PLPPRSKQNN
1010 1020 1030 1040 1050
CAECPQGDFD KIKNKLLQGN VVYRAHHLGV LEIGETECSD EAHAAMTRIK
1060 1070 1080 1090 1100
ESIIDWETIP RVTLDLTCNG ITIFDETFKT LLDGYGVYTI RVVCQDRKDL
1110 1120 1130 1140 1150
NFFCFVARDT ENRFFCHTFC VLTSGIAAEI ITTIGMMFEL RSRMDKSLPI
1160 1170
EGTMVRCRHN SQQTTENQRN
Length:1,170
Mass (Da):132,431
Last modified:October 1, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i910468625DF1F9A8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CAB02658.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T19193

NCBI Reference Sequences

More...
RefSeqi
NP_509620.2, NM_077219.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
C11E4.6.1; C11E4.6.1; WBGene00007520

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
181179

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_C11E4.6

UCSC genome browser

More...
UCSCi
C11E4.6 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA Translation: CAB02658.2
PIRiT19193
RefSeqiNP_509620.2, NM_077219.5

3D structure databases

SMRiQ93203
ModBaseiSearch...

Protein-protein interaction databases

DIPiDIP-25879N
IntActiQ93203, 10 interactors
MINTiQ93203
STRINGi6239.C11E4.6

Proteomic databases

EPDiQ93203
PaxDbiQ93203

Genome annotation databases

EnsemblMetazoaiC11E4.6.1; C11E4.6.1; WBGene00007520
GeneIDi181179
KEGGicel:CELE_C11E4.6
UCSCiC11E4.6 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
181179
WormBaseiC11E4.6 ; CE31411 ; WBGene00007520

Phylogenomic databases

eggNOGiENOG410IQT9 Eukaryota
ENOG4111F95 LUCA
HOGENOMiHOG000020725
InParanoidiQ93203
KOiK21413
OMAiQQEDNDP
OrthoDBi549581at2759
PhylomeDBiQ93203

Gene expression databases

BgeeiWBGene00007520 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

Gene3Di1.10.150.50, 1 hit
1.25.40.20, 2 hits
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF00640 PID, 1 hit
PF00536 SAM_1, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SM00462 PTB, 1 hit
SM00454 SAM, 2 hits
SUPFAMiSSF47769 SSF47769, 1 hit
SSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS01179 PID, 1 hit
PS50105 SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ93203_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q93203
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: October 1, 2002
Last modified: October 16, 2019
This is version 160 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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