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UniProtKB - Q93098 (WNT8B_HUMAN)

Entry version 166 (12 Aug 2020)
Sequence version 3 (24 May 2005)
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Protein

Protein Wnt-8b

Gene

WNT8B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processWnt signaling pathway

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q93098

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-201681, TCF dependent signaling in response to WNT
R-HSA-3238698, WNT ligand biogenesis and trafficking
R-HSA-373080, Class B/2 (Secretin family receptors)
R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q93098

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein Wnt-8b
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WNT8B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000075290.7

Human Gene Nomenclature Database

More...HGNCi		HGNC:12789, WNT8B

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		601396, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q93098

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		7479

Open Targets

More...OpenTargetsi		ENSG00000075290

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA37390

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q93098, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		WNT8B

Domain mapping of disease mutations (DMDM)

More...DMDMi		66774217

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004145023 – 351Protein Wnt-8bAdd BLAST329

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi54 ↔ 65By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi103N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi104 ↔ 112By similarity
Disulfide bondi114 ↔ 132By similarity
Disulfide bondi180 ↔ 194By similarity
Disulfide bondi182 ↔ 189By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi186O-palmitoleoyl serineBy similarity1
Disulfide bondi256 ↔ 294By similarity
Glycosylationi259N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi272 ↔ 287By similarity
Disulfide bondi291 ↔ 333By similarity
Disulfide bondi309 ↔ 324By similarity
Disulfide bondi311 ↔ 321By similarity
Disulfide bondi316 ↔ 317By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Palmitoleoylation is required for efficient binding to frizzled receptors (By similarity). Depalmitoleoylation leads to Wnt signaling pathway inhibition (By similarity).By similarity
Proteolytic processing by TIKI1 and TIKI2 promotes oxidation and formation of large disulfide-bond oligomers, leading to inactivation of WNT8B.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q93098

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q93098

PeptideAtlas

More...PeptideAtlasi		Q93098

PRoteomics IDEntifications database

More...PRIDEi		Q93098

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		75724

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q93098, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q93098

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expression is restricted to the brain, and more specifically to the forebrain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000075290, Expressed in adult mammalian kidney and 29 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q93098, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q93098, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000075290, Tissue enhanced (adrenal gland, parathyroid gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		Q93098, 2 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000340677

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q93098, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q93098

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Wnt family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3913, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160584

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_033039_1_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q93098

KEGG Orthology (KO)

More...KOi		K00714

Identification of Orthologs from Complete Genome Data

More...OMAi		NCGCDDT

Database of Orthologous Groups

More...OrthoDBi		618621at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q93098

TreeFam database of animal gene trees

More...TreeFami		TF105310

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.2460.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR034311, Protein_Wnt-8B
IPR005817, Wnt
IPR013301, Wnt8
IPR043158, Wnt_C
IPR018161, Wnt_CS

The PANTHER Classification System

More...PANTHERi		PTHR12027, PTHR12027, 1 hit
PTHR12027:SF94, PTHR12027:SF94, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00110, wnt, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01892, WNT8PROTEIN
PR01349, WNTPROTEIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00097, WNT1, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00246, WNT1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q93098-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFLSKPSVYI CLFTCVLQLS HSWSVNNFLM TGPKAYLIYS SSVAAGAQSG 
        60         70         80         90        100
IEECKYQFAW DRWNCPERAL QLSSHGGLRS ANRETAFVHA ISSAGVMYTL 
       110        120        130        140        150
TRNCSLGDFD NCGCDDSRNG QLGGQGWLWG GCSDNVGFGE AISKQFVDAL 
       160        170        180        190        200
ETGQDARAAM NLHNNEAGRK AVKGTMKRTC KCHGVSGSCT TQTCWLQLPE 
       210        220        230        240        250
FREVGAHLKE KYHAALKVDL LQGAGNSAAG RGAIADTFRS ISTRELVHLE 
       260        270        280        290        300
DSPDYCLENK TLGLLGTEGR ECLRRGRALG RWERRSCRRL CGDCGLAVEE 
       310        320        330        340        350
RRAETVSSCN CKFHWCCAVR CEQCRRRVTK YFCSRAERPR GGAAHKPGRK 

P
Length:351
Mass (Da):38,721
Last modified:May 24, 2005 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDD242070948813F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti230G → A (PubMed:9536085).Curated1
Sequence conflicti230G → A (PubMed:8661156).Curated1
Sequence conflicti284R → L (PubMed:9536085).Curated1
Sequence conflicti284R → L (PubMed:8661156).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02031011C → S. Corresponds to variant dbSNP:rs3793771Ensembl.1
Natural variantiVAR_03628853E → Q in a colorectal cancer sample; somatic mutation. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y11094 mRNA Translation: CAA71968.1
Y11108 Genomic DNA Translation: CAA71994.1
AB073637 mRNA Translation: BAB83924.1
AL359759 Genomic DNA No translation available.
AL133352 Genomic DNA No translation available.
X91940 mRNA Translation: CAA63017.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS7494.1

NCBI Reference Sequences

More...RefSeqi		NP_003384.2, NM_003393.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000343737; ENSP00000340677; ENSG00000075290

Database of genes from NCBI RefSeq genomes

More...GeneIDi		7479

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:7479

UCSC genome browser

More...UCSCi		uc001krb.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11094 mRNA Translation: CAA71968.1
Y11108 Genomic DNA Translation: CAA71994.1
AB073637 mRNA Translation: BAB83924.1
AL359759 Genomic DNA No translation available.
AL133352 Genomic DNA No translation available.
X91940 mRNA Translation: CAA63017.1
CCDSiCCDS7494.1
RefSeqiNP_003384.2, NM_003393.3

3D structure databases

SMRiQ93098
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ93098, 2 interactors
STRINGi9606.ENSP00000340677

PTM databases

GlyGeniQ93098, 2 sites
iPTMnetiQ93098

Polymorphism and mutation databases

BioMutaiWNT8B
DMDMi66774217

Proteomic databases

MassIVEiQ93098
PaxDbiQ93098
PeptideAtlasiQ93098
PRIDEiQ93098
ProteomicsDBi75724

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		17653, 222 antibodies

The DNASU plasmid repository

More...DNASUi		7479

Genome annotation databases

EnsembliENST00000343737; ENSP00000340677; ENSG00000075290
GeneIDi7479
KEGGihsa:7479
UCSCiuc001krb.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7479
DisGeNETi7479
EuPathDBiHostDB:ENSG00000075290.7

GeneCards: human genes, protein and diseases

More...GeneCardsi		WNT8B
HGNCiHGNC:12789, WNT8B
HPAiENSG00000075290, Tissue enhanced (adrenal gland, parathyroid gland)
MIMi601396, gene
neXtProtiNX_Q93098
OpenTargetsiENSG00000075290
PharmGKBiPA37390

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3913, Eukaryota
GeneTreeiENSGT00940000160584
HOGENOMiCLU_033039_1_2_1
InParanoidiQ93098
KOiK00714
OMAiNCGCDDT
OrthoDBi618621at2759
PhylomeDBiQ93098
TreeFamiTF105310

Enzyme and pathway databases

PathwayCommonsiQ93098
ReactomeiR-HSA-201681, TCF dependent signaling in response to WNT
R-HSA-3238698, WNT ligand biogenesis and trafficking
R-HSA-373080, Class B/2 (Secretin family receptors)
R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane
SIGNORiQ93098

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		7479, 4 hits in 873 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		WNT8B

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		7479
PharosiQ93098, Tbio

Protein Ontology

More...PROi		PR:Q93098
RNActiQ93098, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000075290, Expressed in adult mammalian kidney and 29 other tissues
ExpressionAtlasiQ93098, baseline and differential
GenevisibleiQ93098, HS

Family and domain databases

Gene3Di3.30.2460.20, 1 hit
InterProiView protein in InterPro
IPR034311, Protein_Wnt-8B
IPR005817, Wnt
IPR013301, Wnt8
IPR043158, Wnt_C
IPR018161, Wnt_CS
PANTHERiPTHR12027, PTHR12027, 1 hit
PTHR12027:SF94, PTHR12027:SF94, 1 hit
PfamiView protein in Pfam
PF00110, wnt, 1 hit
PRINTSiPR01892, WNT8PROTEIN
PR01349, WNTPROTEIN
SMARTiView protein in SMART
SM00097, WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246, WNT1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWNT8B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q93098
Secondary accession number(s): O00771, Q5VX55, Q8WYK9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 24, 2005
Last modified: August 12, 2020
This is version 166 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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