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Entry version 91 (29 Sep 2021)
Sequence version 2 (06 Jun 2002)
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Protein

Probable phosphoketolase 2

Gene

RA0587

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

thiamine diphosphateCurated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyase
LigandThiamine pyrophosphate

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable phosphoketolase 2 (EC:4.1.2.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:RA0587
ORF Names:SMa1084
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pSymA (megaplasmid 1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri266834 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaHyphomicrobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001976 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Plasmid pSymA

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001938871 – 779Probable phosphoketolase 2Add BLAST779

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q92ZA4

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q92ZA4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the XFP family.Curated

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013954_2_0_5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.920, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01403, Phosphoketolase, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023962, Phosphoketolase
IPR029061, THDP-binding
IPR009014, Transketo_C/PFOR_II
IPR005593, Xul5P/Fru6P_PKetolase
IPR018969, Xul5P/Fru6P_PKetolase_C
IPR019790, Xul5P/Fru6P_PKetolase_CS
IPR018970, Xul5P/Fru6P_PKetolase_N
IPR019789, Xul5P/Fru6P_PKetolase_ThDP_BS

The PANTHER Classification System

More...
PANTHERi
PTHR31273, PTHR31273, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03894, XFP, 1 hit
PF09363, XFP_C, 1 hit
PF09364, XFP_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017245, Phosphoketolase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52518, SSF52518, 2 hits
SSF52922, SSF52922, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS60002, PHOSPHOKETOLASE_1, 1 hit
PS60003, PHOSPHOKETOLASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q92ZA4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAYWRAANY LSVGQIYLRD NPLLKQKLTL ADVKPRLLGH WGTTPGLNFL
60 70 80 90 100
YVHLNRLIQT HDLNMIYVTG PGHGGPGLVA NTYLEGTYSE LYPEVSQDEA
110 120 130 140 150
GIKRLFTQFS YPGGIPSHVA AEVPGSINEG GELGYCLMHA YGAVFDNPDL
160 170 180 190 200
IAACVVGDGE AETGALATSW HSNKFLNPAR DGAVLPILHL NGYKIANPTV
210 220 230 240 250
LARISHDELE ALFMGYGYEP LFVEGADPRQ MHQLMASALD KAHGKIAEIQ
260 270 280 290 300
RQARSRGFSD RPAWPMIIFR SPKGWTGPRE VDGKKTEGTW RSHQVPLAKL
310 320 330 340 350
AEVPAHLGIL EEWLKSYRPW ELFDESGSLR PELRELAPKG ERRMGANPHA
360 370 380 390 400
NGGLLLKDLN LPDFRQYAVE IGIPGTVTAE STRTAGLYLR DVMKLNAQER
410 420 430 440 450
NFRIFGPDET ESNRLSPVFQ ETDRVFTGDI LASDMQLSPD GRVMEVLSEQ
460 470 480 490 500
LCQGWLEGYL LTGRHGFFSC YEAFIHIVDS MFNQHAKWLK VCREVPWRKP
510 520 530 540 550
IASLTYLLTS HVWRQDHNGF SHQDPGFIDH VANKKADIIR VYLPPDANTL
560 570 580 590 600
LSVVDHCARS RDYINVIVAG KQPQLQWLDM GAAVAHCRAG LGVWEWASND
610 620 630 640 650
EGDPDAVVAC AGDVPTMEAL AAVMIVREAF PSLRLRVVNV VDLMALQAPS
660 670 680 690 700
QHPHGIADDA FDRMFTTDKP VIFAYHGYPG LIHRLTYRRT NHANFHVHGY
710 720 730 740 750
QEEGTTTTPF DMAVLNKLDR FHLAKAVVER VPSLASPREG FAHFVESKLA
760 770
EHDAYIRENG EDLPEIRNWR WLASAVDAQ
Length:779
Mass (Da):87,068
Last modified:June 6, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F857C17673A11D6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK65245 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE006469 Genomic DNA Translation: AAK65245.1 Different initiation.

Protein sequence database of the Protein Information Resource

More...
PIRi
C95335

NCBI Reference Sequences

More...
RefSeqi
NP_435833.1, NC_003037.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAK65245; AAK65245; SMa1084

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sme:SMa1084

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|266834.11.peg.602

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006469 Genomic DNA Translation: AAK65245.1 Different initiation.
PIRiC95335
RefSeqiNP_435833.1, NC_003037.1

3D structure databases

SMRiQ92ZA4
ModBaseiSearch...

Proteomic databases

PRIDEiQ92ZA4

Genome annotation databases

EnsemblBacteriaiAAK65245; AAK65245; SMa1084
KEGGisme:SMa1084
PATRICifig|266834.11.peg.602

Phylogenomic databases

HOGENOMiCLU_013954_2_0_5

Family and domain databases

Gene3Di3.40.50.920, 1 hit
HAMAPiMF_01403, Phosphoketolase, 1 hit
InterProiView protein in InterPro
IPR023962, Phosphoketolase
IPR029061, THDP-binding
IPR009014, Transketo_C/PFOR_II
IPR005593, Xul5P/Fru6P_PKetolase
IPR018969, Xul5P/Fru6P_PKetolase_C
IPR019790, Xul5P/Fru6P_PKetolase_CS
IPR018970, Xul5P/Fru6P_PKetolase_N
IPR019789, Xul5P/Fru6P_PKetolase_ThDP_BS
PANTHERiPTHR31273, PTHR31273, 1 hit
PfamiView protein in Pfam
PF03894, XFP, 1 hit
PF09363, XFP_C, 1 hit
PF09364, XFP_N, 1 hit
PIRSFiPIRSF017245, Phosphoketolase, 1 hit
SUPFAMiSSF52518, SSF52518, 2 hits
SSF52922, SSF52922, 1 hit
PROSITEiView protein in PROSITE
PS60002, PHOSPHOKETOLASE_1, 1 hit
PS60003, PHOSPHOKETOLASE_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPHK2_RHIME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92ZA4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: September 29, 2021
This is version 91 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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