UniProtKB - Q92SH4 (TRUA_RHIME)
Protein
tRNA pseudouridine synthase A
Gene
truA
Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Functioni
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation
Catalytic activityi
- EC:5.4.99.12UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 52 | NucleophileUniRule annotation | 1 | |
Binding sitei | 113 | SubstrateUniRule annotation | 1 |
GO - Molecular functioni
- RNA binding Source: InterPro
- tRNA pseudouridine synthase activity Source: UniProtKB-EC
GO - Biological processi
- tRNA pseudouridine synthesis Source: UniProtKB-UniRule
Keywordsi
Molecular function | Isomerase |
Biological process | tRNA processing |
Names & Taxonomyi
Protein namesi | Recommended name: tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)Alternative name(s): tRNA pseudouridine(38-40) synthaseUniRule annotation tRNA pseudouridylate synthase IUniRule annotation tRNA-uridine isomerase IUniRule annotation |
Gene namesi | Name:truAUniRule annotation Ordered Locus Names:R00421 ORF Names:SMc01099 |
Organismi | Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) |
Taxonomic identifieri | 266834 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000057437 | 1 – 247 | tRNA pseudouridine synthase AAdd BLAST | 247 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
STRINGi | 266834.SMc01099 |
Family & Domainsi
Sequence similaritiesi
Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0101, Bacteria |
HOGENOMi | CLU_014673_0_2_5 |
OMAi | FLYGMVR |
Family and domain databases
Gene3Di | 3.30.70.660, 1 hit |
HAMAPi | MF_00171, TruA, 1 hit |
InterProi | View protein in InterPro IPR020103, PsdUridine_synth_cat_dom_sf IPR001406, PsdUridine_synth_TruA IPR020097, PsdUridine_synth_TruA_a/b_dom IPR020095, PsdUridine_synth_TruA_C |
PANTHERi | PTHR11142, PTHR11142, 1 hit |
Pfami | View protein in Pfam PF01416, PseudoU_synth_1, 2 hits |
PIRSFi | PIRSF001430, tRNA_psdUrid_synth, 1 hit |
SUPFAMi | SSF55120, SSF55120, 1 hit |
TIGRFAMsi | TIGR00071, hisT_truA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q92SH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRYRLTVEY DGSDYVGWQR QDNGPSVQGA IEKAVLSLTR ETVSIRGAGR
60 70 80 90 100
TDSGVHARGQ VAHLDLTREW KSYTLQNALN AHLALAGERV SILDVAEAPG
110 120 130 140 150
DFDARFSAIR RHYLYRIISR RSPLALEARR AWWVPKPLDH DAMHEAAQRL
160 170 180 190 200
VGHHDFTTFR SAHCQATSPL RTLDRLDVTR AGELIEIRAT AQSFLHNQIR
210 220 230 240
SFAGSLKLVG EGKWTPDDLQ AALEARDRKA CGPVAPPDGL YFMRVDY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL591688 Genomic DNA Translation: CAC41858.1 |
RefSeqi | NP_384527.1, NC_003047.1 WP_010968563.1, NC_003047.1 |
Genome annotation databases
EnsemblBacteriai | CAC41858; CAC41858; SMc01099 |
KEGGi | sme:SMc01099 |
PATRICi | fig|266834.11.peg.1794 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL591688 Genomic DNA Translation: CAC41858.1 |
RefSeqi | NP_384527.1, NC_003047.1 WP_010968563.1, NC_003047.1 |
3D structure databases
SMRi | Q92SH4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 266834.SMc01099 |
Genome annotation databases
EnsemblBacteriai | CAC41858; CAC41858; SMc01099 |
KEGGi | sme:SMc01099 |
PATRICi | fig|266834.11.peg.1794 |
Phylogenomic databases
eggNOGi | COG0101, Bacteria |
HOGENOMi | CLU_014673_0_2_5 |
OMAi | FLYGMVR |
Family and domain databases
Gene3Di | 3.30.70.660, 1 hit |
HAMAPi | MF_00171, TruA, 1 hit |
InterProi | View protein in InterPro IPR020103, PsdUridine_synth_cat_dom_sf IPR001406, PsdUridine_synth_TruA IPR020097, PsdUridine_synth_TruA_a/b_dom IPR020095, PsdUridine_synth_TruA_C |
PANTHERi | PTHR11142, PTHR11142, 1 hit |
Pfami | View protein in Pfam PF01416, PseudoU_synth_1, 2 hits |
PIRSFi | PIRSF001430, tRNA_psdUrid_synth, 1 hit |
SUPFAMi | SSF55120, SSF55120, 1 hit |
TIGRFAMsi | TIGR00071, hisT_truA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TRUA_RHIME | |
Accessioni | Q92SH4Primary (citable) accession number: Q92SH4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 16, 2003 |
Last sequence update: | December 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families