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Entry version 90 (26 Feb 2020)
Sequence version 1 (01 Dec 2001)
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Protein

Putative surface cell antigen sca1

Gene

sca1

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
RCON272944:G1FZG-34-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative surface cell antigen sca1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sca1
Ordered Locus Names:RC0019
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272944 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000816 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025974229 – 1902Putative surface cell antigen sca1Add BLAST1874

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q92JP8

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1618 – 1902AutotransporterPROSITE-ProRule annotationAdd BLAST285

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002510_0_0_5

Identification of Orthologs from Complete Genome Data

More...
OMAi
KTTYSYG

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.130, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03797 Autotransporter, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00869 Autotransporter, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103515 SSF103515, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q92JP8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKLTEQHLL KKSRFLKYSL LASISVGAAI PFEGMAMSKE AFRIDLSNKL
60 70 80 90 100
LNHVSQLNGY KDTTNNTPQQ IGKVIVSEPK INTYTPSEIR EMKISNKPKA
110 120 130 140 150
SNPLKDVPIE DHYKVVARSK SDVGTARKVR PITRCKTFAG IEKTEQSQNT
160 170 180 190 200
YTPESTEQMP QKPEIIITAS SPTVSPASNS FITAPNTPNT TLTSPEHYTT
210 220 230 240 250
APGTPSSTPA TPYQSTSDSK PNDSLGANTP PNINTNSKAV RRLSFSSSGP
260 270 280 290 300
QQQAVQSSSQ VKSEVPPKPT FVPLPIKKSS TEIVAGMVSN ISRVNEMIGI
310 320 330 340 350
KLAEVTQAID TTDKKDKERL QKLYTQLTST QKTTEKLKSR AEEIETKIKI
360 370 380 390 400
GENKDKIKKL EKELTSKNNK ADRLFQKIEK IDIPANKVSI KSQETVPVTT
410 420 430 440 450
ASTEVSAFQA QQARINEARQ GVFNKNKSSG GNARKSSAGT KREKKKQEAQ
460 470 480 490 500
KQLSEIKKQE KAIKTASDKA KEVAASAKKE TSRTALRAMQ DKMNGDSEQL
510 520 530 540 550
NKIEENLKLL TPVVYNSSTG PTYKQSPKAT PTIPLSHGVQ RILGEQPEDE
560 570 580 590 600
EGYLVPIKVQ QQPYQEIEDP IPSHSKDIYE AKVSQYINYL NSIQPNQSNQ
610 620 630 640 650
AQIDSVIDGL ATEMRKFSAD QFSQKLGEIA HLASIKAYEG LFEKLYEIQQ
660 670 680 690 700
ARILETQKVY EQAEISQSYA EYEENSRKSS IPVLSRSSSA KSVISSNFEE
710 720 730 740 750
KSALLQTTTT DESLRSDNNW KNSAPYSSSP KLDKRGLEYL DLAGDAFVQN
760 770 780 790 800
LKQPDTLTIE TLGLITPTQN TTVAKSDSSR KNNVSGSISE IQQLQSEKMR
810 820 830 840 850
TETLGVQDDL GLDLHYTPQE TLTEKSTYLV SSKKKQGNII KRAVSKVGSI
860 870 880 890 900
LQTNYAENRR RKRDGETSKQ RTVDQEGEFG HAWGNENHKE SSLSVVSGCI
910 920 930 940 950
KKATQLISLL DAKRTAILQT TSPSQRRSVS LVLQEIENDY REAIKISQKL
960 970 980 990 1000
QQVLIRKPED IKAYNAKAEK KLDAIKSRAD KHFNNIETDV DVGFNPNGGN
1010 1020 1030 1040 1050
SHSMPTANMD ILPKNLAVTP PTNVGSLYNS PQAQQFQEDH KNIIINDRSQ
1060 1070 1080 1090 1100
GRLNLVDSTI VRELTDVDAS IYNTAPPEVL KEAEALLDRS QGRLNLVDNT
1110 1120 1130 1140 1150
IKKGTQPLSN LSTIYESVSY ENLASETIYK TEQPKPSISY TNTSKRKLPI
1160 1170 1180 1190 1200
PLFRSAELDK KLEYLDLEDK LLEVEEARIV KEKEAIAKLN QYQDPENLEF
1210 1220 1230 1240 1250
KRLAMEALDL SSKESQLKQK RKAIEAEFSL NEKSSSTDVS ILRSYSIDDI
1260 1270 1280 1290 1300
SGVLSDAESN LSRSPSVSGL EDLNNSNVMQ LEELKSKHEK IANDYNKELE
1310 1320 1330 1340 1350
LDTLNKEKIW LEGEIKHLDT EFKPKVTESK PVFSCSSSVG SINSFSNDDD
1360 1370 1380 1390 1400
LSSRDVVTPV DTLNIEINKD YVDTYIRVLS NKIQKIEEIQ KIEELSGSSS
1410 1420 1430 1440 1450
RSEELNHIKE AMAYISNRIQ DVEELDEKML LAINAQLQEH DEKISSLLRE
1460 1470 1480 1490 1500
EATDILAQLL LQEMLVSDGK SESTLPAGDE EQEDTEVSRQ LSSLPALASS
1510 1520 1530 1540 1550
NESALALSDD REKECLALGD SSEDEESYDS GFEEEEETIG QLSDSDGDNL
1560 1570 1580 1590 1600
KITEVDTVIP LEQEAKKEMQ TQISENAPTL NQAKVVNTIV NNMIRNRLDA
1610 1620 1630 1640 1650
SMNMSNNMVA VGAGDEEESH IKRGLWMRGM YGTNNHGRVE NMTGYRGTNK
1660 1670 1680 1690 1700
GATIGFDAEI DNNIVGIAYS NVHSVFKFKN SKNNDKELIN SHVVSIYGQK
1710 1720 1730 1740 1750
ELPKNFALQA LVSASKNFIK DKTTYSYGDT KIKSNVKHRN HSYNAEALLH
1760 1770 1780 1790 1800
YNYLLQSKLV ITPNIGLRYG KSRDGVYNET GVNVQEIALT MKENNILSGI
1810 1820 1830 1840 1850
VGTKVTVPLK DALKFNNLGL IFQGAVEHNF KEKTQRINRV VKIFDNTFKH
1860 1870 1880 1890 1900
NYLIPKQPKT SYNLGTGIIG SIKNTTISLD YNYYLNKHYR SHQGSVKLKV

NL
Length:1,902
Mass (Da):212,153
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF2D817457EF1912A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL02557.1
DQ306906 Genomic DNA Translation: ABC41076.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C97702

NCBI Reference Sequences

More...
RefSeqi
WP_010976707.1, NC_003103.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAL02557; AAL02557; RC0019

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
928642

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rco:RC0019

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|272944.4.peg.21

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL02557.1
DQ306906 Genomic DNA Translation: ABC41076.1
PIRiC97702
RefSeqiWP_010976707.1, NC_003103.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PRIDEiQ92JP8

Genome annotation databases

EnsemblBacteriaiAAL02557; AAL02557; RC0019
GeneIDi928642
KEGGirco:RC0019
PATRICifig|272944.4.peg.21

Phylogenomic databases

HOGENOMiCLU_002510_0_0_5
OMAiKTTYSYG

Enzyme and pathway databases

BioCyciRCON272944:G1FZG-34-MONOMER

Family and domain databases

Gene3Di2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf
PfamiView protein in Pfam
PF03797 Autotransporter, 1 hit
SMARTiView protein in SMART
SM00869 Autotransporter, 1 hit
SUPFAMiSSF103515 SSF103515, 1 hit
PROSITEiView protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCA1_RICCN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92JP8
Secondary accession number(s): Q20DN5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: December 1, 2001
Last modified: February 26, 2020
This is version 90 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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