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Protein

Peptide chain release factor 2

Gene

prfB

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 2UniRule annotation
Short name:
RF-2UniRule annotation
Gene namesi
Name:prfBUniRule annotation
Ordered Locus Names:RC0368
OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)
Taxonomic identifieri272944 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000000816 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001668381 – 368Peptide chain release factor 2Add BLAST368

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei250N5-methylglutamineUniRule annotation1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF2.UniRule annotation

Keywords - PTMi

Methylation

Structurei

3D structure databases

ProteinModelPortaliQ92IQ2
SMRiQ92IQ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000074814
KOiK02836
OMAiYVFHPYQ
OrthoDBiPOG091H027X

Family and domain databases

HAMAPiMF_00094 Rel_fac_2, 1 hit
InterProiView protein in InterPro
IPR005139 PCRF
IPR000352 Pep_chain_release_fac_I_II
IPR004374 PrfB
PfamiView protein in Pfam
PF03462 PCRF, 1 hit
PF00472 RF-1, 1 hit
SMARTiView protein in SMART
SM00937 PCRF, 1 hit
TIGRFAMsiTIGR00020 prfB, 1 hit
PROSITEiView protein in PROSITE
PS00745 RF_PROK_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q92IQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAEIENYVK KIEQSLELLW RSLDVEASTE RLNALEELTA DPSLWNDQAN
60 70 80 90 100
AQKLLREKSN LEEKLNAFNK LKSNLKDALE LEEMAEAEND LETLSQIEQD
110 120 130 140 150
LKNLSIIAAK FETECLFSGE ADGNNCFLEI NAGAGGTESH DWASIMMRMY
160 170 180 190 200
LRFAERLGFK TEIINMINGE EAGIKSCTIR IIGKRAYGWF KTETGVHRLV
210 220 230 240 250
RISPFNAAGK RMTSFASSWV YPEIDDNIAI TIEDKDLRID TFRASGAGGQ
260 270 280 290 300
HVNTTDSAVR ITHIPTGTVT QCQSDRSQHK NKAQAMKMLQ AKLYELEMQK
310 320 330 340 350
RTDSVNEQNA AKTDNSWGHQ IRSYVLQPYH MVKDLRTDYE TSDTKGVLDG
360
DLEEFVSAHL AMNVGGKK
Length:368
Mass (Da):41,540
Last modified:December 1, 2001 - v1
Checksum:iA63C0FD338F7081F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL02906.1
PIRiH97745

Genome annotation databases

EnsemblBacteriaiAAL02906; AAL02906; RC0368
KEGGirco:RC0368

Similar proteinsi

Entry informationi

Entry nameiRF2_RICCN
AccessioniPrimary (citable) accession number: Q92IQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: December 1, 2001
Last modified: December 20, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia conorii
    (strain Malish 7): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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