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Entry version 94 (29 Sep 2021)
Sequence version 1 (01 Dec 2001)
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Protein

Probable lipid II flippase MurJ

Gene

mviN

Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferaseImported, Transferase
Biological processCell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation, TransportUniRule annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00219

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable lipid II flippase MurJUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mviNImported
Synonyms:murJUniRule annotation
Ordered Locus Names:RC0898Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRickettsia conorii (strain ATCC VR-613 / Malish 7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272944 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000816 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei51 – 71HelicalUniRule annotationAdd BLAST21
Transmembranei137 – 161HelicalUniRule annotationAdd BLAST25
Transmembranei173 – 197HelicalUniRule annotationAdd BLAST25
Transmembranei204 – 225HelicalUniRule annotationAdd BLAST22
Transmembranei231 – 254HelicalUniRule annotationAdd BLAST24
Transmembranei358 – 378HelicalUniRule annotationAdd BLAST21
Transmembranei398 – 419HelicalUniRule annotationAdd BLAST22
Transmembranei431 – 447HelicalUniRule annotationAdd BLAST17
Transmembranei453 – 473HelicalUniRule annotationAdd BLAST21
Transmembranei485 – 507HelicalUniRule annotationAdd BLAST23
Transmembranei519 – 545HelicalUniRule annotationAdd BLAST27

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MurJ/MviN family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006797_5_0_5

Identification of Orthologs from Complete Genome Data

More...
OMAi
IFFVAFK

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13123, MATE_MurJ_like, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_02078, MurJ_MviN, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004268, MurJ
IPR005728, Rickett_RPE

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03023, MurJ, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002869, MviN, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01806, VIRFACTRMVIN

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01695, murJ_mviN, 1 hit
TIGR01045, RPE1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q92H73-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDFLHNVAN KEKFEGNTER STAAYTLVRE NASTGLTHKL PLEASYARSR
60 70 80 90 100
LFRSGVVVAF FTLISRIFGL VREQFIASLF GSTPMGDSIN VAFKLPNLFR
110 120 130 140 150
RIFAEGALSS VFIPIYNEKM LISKKAANNF SGEIFTLLLL TLIVIIALMQ
160 170 180 190 200
IFMPQLMLFI VPGFHGKKEK FELTVFLCRI TIPYLIFVSL TALLGGILNS
210 220 230 240 250
IKKFAAFAFS PVILSICVII FTLTFDHYIE STISISLSLI IAGILQVSFM
260 270 280 290 300
FVCVKRADLN FPIIFNPSDP DVKKLLINMG PATISSGIQQ LNLFISQSIA
310 320 330 340 350
SFIEGAISIL SYADRIYQFP LSIIGTSFST ILLPELSKIY KSNDIVAAKK
360 370 380 390 400
IQNNAIKMGL LLSLPATFGI IILSHPIINI IYERGVFTSQ DTTNTAEAIS
410 420 430 440 450
AFALGLPAFI LAKILTPIFY ANGDTKTPLK ITLFSIIINT GMNLLLMDSL
460 470 480 490 500
KHIGIAVGTS IAAWYNLGLL YSYTTKQNKL HIEAGIKLFC GKILLCCILM
510 520 530 540 550
SIIIALIKHY YLEYFYSEYL LIKVCMLGST IAVGMGAFFG TAYLLKTVNY

DNNNK
Length:555
Mass (Da):61,421
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i257E51D5781C3F45
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL03436.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B97812

NCBI Reference Sequences

More...
RefSeqi
WP_010977499.1, NC_003103.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAL03436; AAL03436; RC0898

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rco:RC0898

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|272944.4.peg.1022

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006914 Genomic DNA Translation: AAL03436.1
PIRiB97812
RefSeqiWP_010977499.1, NC_003103.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAAL03436; AAL03436; RC0898
KEGGirco:RC0898
PATRICifig|272944.4.peg.1022

Phylogenomic databases

HOGENOMiCLU_006797_5_0_5
OMAiIFFVAFK

Enzyme and pathway databases

UniPathwayiUPA00219

Family and domain databases

CDDicd13123, MATE_MurJ_like, 1 hit
HAMAPiMF_02078, MurJ_MviN, 1 hit
InterProiView protein in InterPro
IPR004268, MurJ
IPR005728, Rickett_RPE
PfamiView protein in Pfam
PF03023, MurJ, 1 hit
PIRSFiPIRSF002869, MviN, 1 hit
PRINTSiPR01806, VIRFACTRMVIN
TIGRFAMsiTIGR01695, murJ_mviN, 1 hit
TIGR01045, RPE1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ92H73_RICCN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92H73
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 29, 2021
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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