UniProtKB - Q92997 (DVL3_HUMAN)
Segment polarity protein dishevelled homolog DVL-3
DVL3
Functioni
GO - Molecular functioni
- beta-catenin binding Source: BHF-UCL
- frizzled binding Source: UniProtKB
- protease binding Source: UniProtKB
- Rac GTPase binding Source: ParkinsonsUK-UCL
- signaling receptor binding Source: BHF-UCL
GO - Biological processi
- beta-catenin destruction complex disassembly Source: Reactome
- canonical Wnt signaling pathway Source: BHF-UCL
- intracellular signal transduction Source: InterPro
- negative regulation of canonical Wnt signaling pathway Source: Reactome
- non-canonical Wnt signaling pathway Source: BHF-UCL
- non-canonical Wnt signaling pathway via JNK cascade Source: BHF-UCL
- planar cell polarity pathway involved in neural tube closure Source: GO_Central
- positive regulation of GTPase activity Source: ParkinsonsUK-UCL
- positive regulation of JUN kinase activity Source: BHF-UCL
- positive regulation of neuron projection arborization Source: ARUK-UCL
- positive regulation of protein phosphorylation Source: BHF-UCL
- positive regulation of transcription, DNA-templated Source: BHF-UCL
- positive regulation of transcription by RNA polymerase II Source: BHF-UCL
- protein stabilization Source: ParkinsonsUK-UCL
- regulation of cellular protein localization Source: ParkinsonsUK-UCL
- response to drug Source: Ensembl
- Wnt signaling pathway, planar cell polarity pathway Source: BHF-UCL
Keywordsi
Molecular function | Developmental protein |
Biological process | Wnt signaling pathway |
Enzyme and pathway databases
PathwayCommonsi | Q92997 |
Reactomei | R-HSA-201681, TCF dependent signaling in response to WNT R-HSA-201688, WNT mediated activation of DVL R-HSA-4086400, PCP/CE pathway R-HSA-4641258, Degradation of DVL R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-5368598, Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5663220, RHO GTPases Activate Formins R-HSA-9673324, WNT5:FZD7-mediated leishmania damping |
SignaLinki | Q92997 |
SIGNORi | Q92997 |
Protein family/group databases
MoonDBi | Q92997, Predicted |
Names & Taxonomyi
Protein namesi | Recommended name: Segment polarity protein dishevelled homolog DVL-3Short name: Dishevelled-3 Alternative name(s): DSH homolog 3 |
Gene namesi | Name:DVL3 Synonyms:KIAA0208 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000161202.17 |
HGNCi | HGNC:3087, DVL3 |
MIMi | 601368, gene |
neXtProti | NX_Q92997 |
Subcellular locationi
Other locations
- Cytoplasm By similarity
Cytosol
- cytosol Source: ParkinsonsUK-UCL
Nucleus
- nuclear chromatin Source: ParkinsonsUK-UCL
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Involvement in diseasei
Robinow syndrome, autosomal dominant 3 (DRS3)1 Publication
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 271 | R → K: Localizes to plasma membranes. 1 Publication | 1 | |
Mutagenesisi | 342 | R → K: No effect on subcellular location. 1 Publication | 1 | |
Mutagenesisi | 614 | R → K: Localizes to plasma membranes. 1 Publication | 1 |
Keywords - Diseasei
DwarfismOrganism-specific databases
DisGeNETi | 1857 |
GeneReviewsi | DVL3 |
MalaCardsi | DVL3 |
MIMi | 616894, phenotype |
OpenTargetsi | ENSG00000161202 |
Orphaneti | 3107, Autosomal dominant Robinow syndrome |
PharmGKBi | PA27543 |
Miscellaneous databases
Pharosi | Q92997, Tbio |
Chemistry databases
ChEMBLi | CHEMBL6028 |
Polymorphism and mutation databases
BioMutai | DVL3 |
DMDMi | 6919875 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000145749 | 1 – 716 | Segment polarity protein dishevelled homolog DVL-3Add BLAST | 716 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 27 | Omega-N-methylarginine1 Publication | 1 | |
Modified residuei | 48 | PhosphoserineCombined sources | 1 | |
Modified residuei | 125 | PhosphoserineCombined sources | 1 | |
Modified residuei | 192 | PhosphoserineCombined sources1 Publication | 1 | |
Modified residuei | 212 | Omega-N-methylarginine1 Publication | 1 | |
Modified residuei | 271 | Asymmetric dimethylarginine; by PRMT1; alternate1 Publication | 1 | |
Modified residuei | 271 | Symmetric dimethylarginine; by PRMT7; alternate1 Publication | 1 | |
Modified residuei | 342 | Omega-N-methylarginine; alternate2 Publications | 1 | |
Modified residuei | 342 | Symmetric dimethylarginine; by PRMT7; alternate2 Publications | 1 | |
Modified residuei | 346 | Phosphothreonine1 Publication | 1 | |
Modified residuei | 614 | Symmetric dimethylarginine; by PRMT71 Publication | 1 | |
Modified residuei | 697 | PhosphoserineCombined sources | 1 | |
Modified residuei | 698 | Dimethylated arginine; alternate1 Publication | 1 | |
Modified residuei | 698 | Omega-N-methylarginine; alternate1 Publication | 1 | |
Modified residuei | 700 | Phosphoserine1 Publication | 1 |
Post-translational modificationi
Keywords - PTMi
Methylation, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | Q92997 |
MassIVEi | Q92997 |
MaxQBi | Q92997 |
PaxDbi | Q92997 |
PeptideAtlasi | Q92997 |
PRIDEi | Q92997 |
ProteomicsDBi | 5895 75666 [Q92997-1] |
PTM databases
iPTMneti | Q92997 |
PhosphoSitePlusi | Q92997 |
Expressioni
Gene expression databases
Bgeei | ENSG00000161202, Expressed in lower esophagus muscularis layer and 241 other tissues |
ExpressionAtlasi | Q92997, baseline and differential |
Genevisiblei | Q92997, HS |
Organism-specific databases
HPAi | ENSG00000161202, Low tissue specificity |
Interactioni
Subunit structurei
Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity).
Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.
Interacts with CYLD, CEP164 and DAB2.
Interacts with DCDC2.
Interacts with FOXK1 and FOXK2 (PubMed:25805136).
Interacts with DAAM2 (By similarity).
By similarity6 PublicationsBinary interactionsi
Q92997
GO - Molecular functioni
- beta-catenin binding Source: BHF-UCL
- frizzled binding Source: UniProtKB
- protease binding Source: UniProtKB
- Rac GTPase binding Source: ParkinsonsUK-UCL
- signaling receptor binding Source: BHF-UCL
Protein-protein interaction databases
BioGRIDi | 108190, 227 interactors |
DIPi | DIP-34509N |
IntActi | Q92997, 207 interactors |
MINTi | Q92997 |
STRINGi | 9606.ENSP00000316054 |
Chemistry databases
BindingDBi | Q92997 |
Miscellaneous databases
RNActi | Q92997, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 82 | DIXPROSITE-ProRule annotationAdd BLAST | 82 | |
Domaini | 249 – 321 | PDZPROSITE-ProRule annotationAdd BLAST | 73 | |
Domaini | 422 – 496 | DEPPROSITE-ProRule annotationAdd BLAST | 75 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG3571, Eukaryota |
GeneTreei | ENSGT00950000182903 |
HOGENOMi | CLU_012601_1_0_1 |
InParanoidi | Q92997 |
OMAi | HHQKMMG |
OrthoDBi | 474724at2759 |
PhylomeDBi | Q92997 |
TreeFami | TF318198 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 2.30.42.10, 1 hit 3.10.20.380, 1 hit |
InterProi | View protein in InterPro IPR000591, DEP_dom IPR024580, Dishevelled_C-dom IPR008339, Dishevelled_fam IPR003351, Dishevelled_protein_dom IPR001158, DIX IPR038207, DIX_dom_sf IPR015506, Dsh/Dvl-rel IPR008342, DVL3 IPR001478, PDZ IPR036034, PDZ_sf IPR029071, Ubiquitin-like_domsf IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR10878, PTHR10878, 1 hit PTHR10878:SF6, PTHR10878:SF6, 1 hit |
Pfami | View protein in Pfam PF00610, DEP, 1 hit PF02377, Dishevelled, 1 hit PF00778, DIX, 1 hit PF12316, Dsh_C, 1 hit PF00595, PDZ, 1 hit |
PRINTSi | PR01760, DISHEVELLED PR01763, DISHEVELLED3 |
SMARTi | View protein in SMART SM00021, DAX, 1 hit SM00049, DEP, 1 hit SM00228, PDZ, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF50156, SSF50156, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50186, DEP, 1 hit PS50841, DIX, 1 hit PS50106, PDZ, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGETKIIYHL DGQETPYLVK LPLPAERVTL ADFKGVLQRP SYKFFFKSMD
60 70 80 90 100
DDFGVVKEEI SDDNAKLPCF NGRVVSWLVS AEGSHPDPAP FCADNPSELP
110 120 130 140 150
PPMERTGGIG DSRPPSFHPH AGGGSQENLD NDTETDSLVS AQRERPRRRD
160 170 180 190 200
GPEHATRLNG TAKGERRREP GGYDSSSTLM SSELETTSFF DSDEDDSTSR
210 220 230 240 250
FSSSTEQSSA SRLMRRHKRR RRKQKVSRIE RSSSFSSITD STMSLNIITV
260 270 280 290 300
TLNMEKYNFL GISIVGQSNE RGDGGIYIGS IMKGGAVAAD GRIEPGDMLL
310 320 330 340 350
QVNEINFENM SNDDAVRVLR EIVHKPGPIT LTVAKCWDPS PRGCFTLPRS
360 370 380 390 400
EPIRPIDPAA WVSHTAAMTG TFPAYGMSPS LSTITSTSSS ITSSIPDTER
410 420 430 440 450
LDDFHLSIHS DMAAIVKAMA SPESGLEVRD RMWLKITIPN AFIGSDVVDW
460 470 480 490 500
LYHNVEGFTD RREARKYASN LLKAGFIRHT VNKITFSEQC YYIFGDLCGN
510 520 530 540 550
MANLSLHDHD GSSGASDQDT LAPLPHPGAA PWPMAFPYQY PPPPHPYNPH
560 570 580 590 600
PGFPELGYSY GGGSASSQHS EGSRSSGSNR SGSDRRKEKD PKAGDSKSGG
610 620 630 640 650
SGSESDHTTR SSLRGPRERA PSERSGPAAS EHSHRSHHSL ASSLRSHHTH
660 670 680 690 700
PSYGPPGVPP LYGPPMLMMP PPPAAMGPPG APPGRDLASV PPELTASRQS
710
FRMAMGNPSE FFVDVM
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A3B3ITC6 | A0A3B3ITC6_HUMAN | Segment polarity protein dishevelle... | DVL3 | 131 | Annotation score: | ||
F8WCF1 | F8WCF1_HUMAN | Segment polarity protein dishevelle... | DVL3 | 77 | Annotation score: | ||
A0A3B3ISG4 | A0A3B3ISG4_HUMAN | Segment polarity protein dishevelle... | DVL3 | 99 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 2 | G → D in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 76 | S → Y in AAB84228 (PubMed:9344861).Curated | 1 | |
Sequence conflicti | 102 | P → S in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 151 | G → W in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 182 | S → R in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 218 | K → N in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 222 | R → W in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 230 | E → D in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 233 | S → C in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 236 | S → T in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 239 | T → S in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 242 | T → A in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 303 | N → K in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 431 | R → C in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 450 | W → C in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 465 | R → P in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 472 | L → V in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 543 | P → R in AAB65244 (PubMed:9192851).Curated | 1 | |
Sequence conflicti | 553 – 554 | FP → LG in AAB65244 (PubMed:9192851).Curated | 2 | |
Sequence conflicti | 629 | A → T in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 633 | S → I in AAB47447 (PubMed:8817329).Curated | 1 | |
Sequence conflicti | 682 – 716 | PPGRD…FVDVM → LRAATWPQCPRN in BAA13199 (PubMed:9039502).CuratedAdd BLAST | 35 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_036116 | 216 | R → T in a breast cancer sample; somatic mutation. 1 Publication | 1 | |
Natural variantiVAR_025519 | 433 | W → L1 PublicationCorresponds to variant dbSNP:rs17853048Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_053371 | 350 – 367 | SEPIR…SHTAA → T in isoform 2. 1 PublicationAdd BLAST | 18 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U49262 mRNA Translation: AAB47447.1 U75651 mRNA Translation: AAB84228.1 AF006013 mRNA Translation: AAB65244.1 D86963 mRNA Translation: BAA13199.2 Different initiation. AK304686 mRNA Translation: BAG65457.1 AC131235 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78295.1 CH471052 Genomic DNA Translation: EAW78296.1 BC032459 mRNA Translation: AAH32459.1 |
CCDSi | CCDS3253.1 [Q92997-1] |
PIRi | JC5763 |
RefSeqi | NP_004414.3, NM_004423.3 [Q92997-1] |
Genome annotation databases
Ensembli | ENST00000313143; ENSP00000316054; ENSG00000161202 [Q92997-1] ENST00000431765; ENSP00000405885; ENSG00000161202 [Q92997-2] |
GeneIDi | 1857 |
KEGGi | hsa:1857 |
UCSCi | uc003fms.4, human [Q92997-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U49262 mRNA Translation: AAB47447.1 U75651 mRNA Translation: AAB84228.1 AF006013 mRNA Translation: AAB65244.1 D86963 mRNA Translation: BAA13199.2 Different initiation. AK304686 mRNA Translation: BAG65457.1 AC131235 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW78295.1 CH471052 Genomic DNA Translation: EAW78296.1 BC032459 mRNA Translation: AAH32459.1 |
CCDSi | CCDS3253.1 [Q92997-1] |
PIRi | JC5763 |
RefSeqi | NP_004414.3, NM_004423.3 [Q92997-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6V7O | X-ray | 2.90 | C/D | 679-688 | [»] | |
SMRi | Q92997 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 108190, 227 interactors |
DIPi | DIP-34509N |
IntActi | Q92997, 207 interactors |
MINTi | Q92997 |
STRINGi | 9606.ENSP00000316054 |
Chemistry databases
BindingDBi | Q92997 |
ChEMBLi | CHEMBL6028 |
Protein family/group databases
MoonDBi | Q92997, Predicted |
PTM databases
iPTMneti | Q92997 |
PhosphoSitePlusi | Q92997 |
Polymorphism and mutation databases
BioMutai | DVL3 |
DMDMi | 6919875 |
Proteomic databases
jPOSTi | Q92997 |
MassIVEi | Q92997 |
MaxQBi | Q92997 |
PaxDbi | Q92997 |
PeptideAtlasi | Q92997 |
PRIDEi | Q92997 |
ProteomicsDBi | 5895 75666 [Q92997-1] |
Protocols and materials databases
Antibodypediai | 33790, 309 antibodies |
DNASUi | 1857 |
Genome annotation databases
Ensembli | ENST00000313143; ENSP00000316054; ENSG00000161202 [Q92997-1] ENST00000431765; ENSP00000405885; ENSG00000161202 [Q92997-2] |
GeneIDi | 1857 |
KEGGi | hsa:1857 |
UCSCi | uc003fms.4, human [Q92997-1] |
Organism-specific databases
CTDi | 1857 |
DisGeNETi | 1857 |
EuPathDBi | HostDB:ENSG00000161202.17 |
GeneCardsi | DVL3 |
GeneReviewsi | DVL3 |
HGNCi | HGNC:3087, DVL3 |
HPAi | ENSG00000161202, Low tissue specificity |
MalaCardsi | DVL3 |
MIMi | 601368, gene 616894, phenotype |
neXtProti | NX_Q92997 |
OpenTargetsi | ENSG00000161202 |
Orphaneti | 3107, Autosomal dominant Robinow syndrome |
PharmGKBi | PA27543 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3571, Eukaryota |
GeneTreei | ENSGT00950000182903 |
HOGENOMi | CLU_012601_1_0_1 |
InParanoidi | Q92997 |
OMAi | HHQKMMG |
OrthoDBi | 474724at2759 |
PhylomeDBi | Q92997 |
TreeFami | TF318198 |
Enzyme and pathway databases
PathwayCommonsi | Q92997 |
Reactomei | R-HSA-201681, TCF dependent signaling in response to WNT R-HSA-201688, WNT mediated activation of DVL R-HSA-4086400, PCP/CE pathway R-HSA-4641258, Degradation of DVL R-HSA-4641262, Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-5368598, Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5663220, RHO GTPases Activate Formins R-HSA-9673324, WNT5:FZD7-mediated leishmania damping |
SignaLinki | Q92997 |
SIGNORi | Q92997 |
Miscellaneous databases
BioGRID-ORCSi | 1857, 4 hits in 842 CRISPR screens |
ChiTaRSi | DVL3, human |
GeneWikii | DVL3 |
GenomeRNAii | 1857 |
Pharosi | Q92997, Tbio |
PROi | PR:Q92997 |
RNActi | Q92997, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000161202, Expressed in lower esophagus muscularis layer and 241 other tissues |
ExpressionAtlasi | Q92997, baseline and differential |
Genevisiblei | Q92997, HS |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 2.30.42.10, 1 hit 3.10.20.380, 1 hit |
InterProi | View protein in InterPro IPR000591, DEP_dom IPR024580, Dishevelled_C-dom IPR008339, Dishevelled_fam IPR003351, Dishevelled_protein_dom IPR001158, DIX IPR038207, DIX_dom_sf IPR015506, Dsh/Dvl-rel IPR008342, DVL3 IPR001478, PDZ IPR036034, PDZ_sf IPR029071, Ubiquitin-like_domsf IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR10878, PTHR10878, 1 hit PTHR10878:SF6, PTHR10878:SF6, 1 hit |
Pfami | View protein in Pfam PF00610, DEP, 1 hit PF02377, Dishevelled, 1 hit PF00778, DIX, 1 hit PF12316, Dsh_C, 1 hit PF00595, PDZ, 1 hit |
PRINTSi | PR01760, DISHEVELLED PR01763, DISHEVELLED3 |
SMARTi | View protein in SMART SM00021, DAX, 1 hit SM00049, DEP, 1 hit SM00228, PDZ, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit SSF50156, SSF50156, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS50186, DEP, 1 hit PS50841, DIX, 1 hit PS50106, PDZ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DVL3_HUMAN | |
Accessioni | Q92997Primary (citable) accession number: Q92997 Secondary accession number(s): B4E3E5 Q92607 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | May 30, 2000 | |
Last modified: | December 2, 2020 | |
This is version 201 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations