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UniProtKB - Q92949 (FOXJ1_HUMAN)

Entry version 173 (12 Aug 2020)
Sequence version 3 (01 Dec 2000)
Previous versions | rss
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Protein

Forkhead box protein J1

Gene

FOXJ1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor specifically required for the formation of motile cilia (PubMed:31630787). Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi120 – 210Fork-headPROSITE-ProRule annotationAdd BLAST91

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processCilium biogenesis/degradation, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q92949

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Forkhead box protein J1Curated
Alternative name(s):
Forkhead-related protein FKHL131 Publication
Hepatocyte nuclear factor 3 forkhead homolog 41 Publication
Short name:
HFH-41 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FOXJ1Imported
Synonyms:FKHL131 Publication, HFH41 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000129654.7

Human Gene Nomenclature Database

More...HGNCi		HGNC:3816, FOXJ1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		602291, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q92949

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Allergic rhinitis (ALRH)1 Publication
Disease susceptibility may be associated with variations affecting the gene represented in this entry.
Disease descriptionA common disease with complex inheritance characterized by mucosal inflammation caused by allergen exposure.
Related information in OMIM
Ciliary dyskinesia, primary, 43 (CILD43)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA form of primary ciliary dyskinesia, a disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients with this disorder also develop significant obstructive hydrocephalus. Other more variable features include infertility and about a 50% chance of situs inversus or other left-right asymmetry defects. CILD43 inheritance is autosomal dominant.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_083456276 – 421Missing in CILD43; reduced number of cilia and mislocalized basal bodies; defects of axonemal microtubular organization; loss of ability to propel mucous along the surface of the epithelium; abnormal localization of PTK2. 1 PublicationAdd BLAST146
Natural variantiVAR_083457301 – 421Missing in CILD43; reduced number of cilia and mislocalized basal bodies; defects of axonemal microtubular organization; loss of ability to propel mucous along the surface of the epithelium; abnormal localization of PTK2. 1 PublicationAdd BLAST121

Keywords - Diseasei

Ciliopathy, Disease mutation, Primary ciliary dyskinesia

Organism-specific databases

DisGeNET

More...DisGeNETi		2302

MalaCards human disease database

More...MalaCardsi		FOXJ1
MIMi607154, phenotype
618699, phenotype

Open Targets

More...OpenTargetsi		ENSG00000129654

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		244, Primary ciliary dyskinesia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA28233

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q92949, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		FOXJ1

Domain mapping of disease mutations (DMDM)

More...DMDMi		12644465

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000918501 – 421Forkhead box protein J1Add BLAST421

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q92949

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q92949

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q92949

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q92949

PeptideAtlas

More...PeptideAtlasi		Q92949

PRoteomics IDEntifications database

More...PRIDEi		Q92949

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		75620

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q92949

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q92949

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis, oviduct, lung and brain cortex.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in developing lung, kidney and central nervous system.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000129654, Expressed in right uterine tube and 168 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q92949, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q92949, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000129654, Tissue enhanced (brain, epididymis, fallopian tube)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		108591, 22 interactors

Protein interaction database and analysis system

More...IntActi		Q92949, 23 interactors

Molecular INTeraction database

More...MINTi		Q92949

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000323880

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q92949, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q92949

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FOXJ1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2294, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156895

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_050055_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q92949

KEGG Orthology (KO)

More...KOi		K09402

Identification of Orthologs from Complete Genome Data

More...OMAi		TWGPPVE

Database of Orthologous Groups

More...OrthoDBi		1270467at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q92949

TreeFam database of animal gene trees

More...TreeFami		TF333250

Family and domain databases

Conserved Domains Database

More...CDDi		cd00059, FH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001766, Fork_head_dom
IPR018122, TF_fork_head_CS_1
IPR030456, TF_fork_head_CS_2
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00250, Forkhead, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00053, FORKHEAD

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00339, FH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46785, SSF46785, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00657, FORK_HEAD_1, 1 hit
PS00658, FORK_HEAD_2, 1 hit
PS50039, FORK_HEAD_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q92949-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAESWLRLSG AGPAEEAGPE GGLEEPDALD DSLTSLQWLQ EFSILNAKAP 
        60         70         80         90        100
ALPPGGTDPH GYHQVPGSAA PGSPLAADPA CLGQPHTPGK PTSSCTSRSA 
       110        120        130        140        150
PPGLQAPPPD DVDYATNPHV KPPYSYATLI CMAMQASKAT KITLSAIYKW 
       160        170        180        190        200
ITDNFCYFRH ADPTWQNSIR HNLSLNKCFI KVPREKDEPG KGGFWRIDPQ 
       210        220        230        240        250
YAERLLSGAF KKRRLPPVHI HPAFARQAAQ EPSAVPRAGP LTVNTEAQQL 
       260        270        280        290        300
LREFEEATGE AGWGAGEGRL GHKRKQPLPK RVAKVPRPPS TLLPTPEEQG 
       310        320        330        340        350
ELEPLKGNFD WEAIFDAGTL GGELGALEAL ELSPPLSPAS HVDVDLTIHG 
       360        370        380        390        400
RHIDCPATWG PSVEQAADSL DFDETFLATS FLQHPWDESG SGCLPPEPLF 
       410        420 
EAGDATLASD LQDWASVGAF L
Length:421
Mass (Da):45,247
Last modified:December 1, 2000 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA8BB0020CB67F97F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5W → C in CAA67729 (PubMed:9073514).Curated1
Sequence conflicti5W → C in CAA67730 (PubMed:9073514).Curated1
Sequence conflicti11A → T in CAA67729 (PubMed:9073514).Curated1
Sequence conflicti11A → T in CAA67730 (PubMed:9073514).Curated1
Sequence conflicti17 – 22AGPEGG → PAGGR in CAA67729 (PubMed:9073514).Curated6
Sequence conflicti56G → A in AAB09039 (PubMed:9530170).Curated1
Sequence conflicti257A → P in CAA67729 (PubMed:9073514).Curated1
Sequence conflicti257A → P in CAA67730 (PubMed:9073514).Curated1
Sequence conflicti262 – 287GWGAG…AKVPR → VWVQARAGWDISPNTLCPRG GQGPA in CAA67729 (PubMed:9073514).CuratedAdd BLAST26
Sequence conflicti311W → L in AAB09039 (PubMed:9530170).Curated1
Sequence conflicti330L → V in AAB09039 (PubMed:9530170).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_083456276 – 421Missing in CILD43; reduced number of cilia and mislocalized basal bodies; defects of axonemal microtubular organization; loss of ability to propel mucous along the surface of the epithelium; abnormal localization of PTK2. 1 PublicationAdd BLAST146
Natural variantiVAR_083457301 – 421Missing in CILD43; reduced number of cilia and mislocalized basal bodies; defects of axonemal microtubular organization; loss of ability to propel mucous along the surface of the epithelium; abnormal localization of PTK2. 1 PublicationAdd BLAST121

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U69537 mRNA Translation: AAB09039.1
X99349 mRNA Translation: CAA67729.1
X99350, X99351 Genomic DNA Translation: CAA67730.1
AJ272064 Genomic DNA Translation: CAB76562.1
BC046460 mRNA Translation: AAH46460.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32739.1

NCBI Reference Sequences

More...RefSeqi		NP_001445.2, NM_001454.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000322957; ENSP00000323880; ENSG00000129654

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2302

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:2302

UCSC genome browser

More...UCSCi		uc002jqx.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U69537 mRNA Translation: AAB09039.1
X99349 mRNA Translation: CAA67729.1
X99350, X99351 Genomic DNA Translation: CAA67730.1
AJ272064 Genomic DNA Translation: CAB76562.1
BC046460 mRNA Translation: AAH46460.1
CCDSiCCDS32739.1
RefSeqiNP_001445.2, NM_001454.3

3D structure databases

SMRiQ92949
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi108591, 22 interactors
IntActiQ92949, 23 interactors
MINTiQ92949
STRINGi9606.ENSP00000323880

PTM databases

iPTMnetiQ92949
PhosphoSitePlusiQ92949

Polymorphism and mutation databases

BioMutaiFOXJ1
DMDMi12644465

Proteomic databases

jPOSTiQ92949
MassIVEiQ92949
MaxQBiQ92949
PaxDbiQ92949
PeptideAtlasiQ92949
PRIDEiQ92949
ProteomicsDBi75620

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		1443, 231 antibodies

Genome annotation databases

EnsembliENST00000322957; ENSP00000323880; ENSG00000129654
GeneIDi2302
KEGGihsa:2302
UCSCiuc002jqx.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		2302
DisGeNETi2302
EuPathDBiHostDB:ENSG00000129654.7

GeneCards: human genes, protein and diseases

More...GeneCardsi		FOXJ1
HGNCiHGNC:3816, FOXJ1
HPAiENSG00000129654, Tissue enhanced (brain, epididymis, fallopian tube)
MalaCardsiFOXJ1
MIMi602291, gene
607154, phenotype
618699, phenotype
neXtProtiNX_Q92949
OpenTargetsiENSG00000129654
Orphaneti244, Primary ciliary dyskinesia
PharmGKBiPA28233

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2294, Eukaryota
GeneTreeiENSGT00940000156895
HOGENOMiCLU_050055_0_0_1
InParanoidiQ92949
KOiK09402
OMAiTWGPPVE
OrthoDBi1270467at2759
PhylomeDBiQ92949
TreeFamiTF333250

Enzyme and pathway databases

PathwayCommonsiQ92949

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		2302, 6 hits in 892 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FOXJ1, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		FOXJ1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		2302
PharosiQ92949, Tbio

Protein Ontology

More...PROi		PR:Q92949
RNActiQ92949, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000129654, Expressed in right uterine tube and 168 other tissues
ExpressionAtlasiQ92949, baseline and differential
GenevisibleiQ92949, HS

Family and domain databases

CDDicd00059, FH, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766, Fork_head_dom
IPR018122, TF_fork_head_CS_1
IPR030456, TF_fork_head_CS_2
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250, Forkhead, 1 hit
PRINTSiPR00053, FORKHEAD
SMARTiView protein in SMART
SM00339, FH, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00657, FORK_HEAD_1, 1 hit
PS00658, FORK_HEAD_2, 1 hit
PS50039, FORK_HEAD_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFOXJ1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q92949
Secondary accession number(s): O00630
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 1, 2000
Last modified: August 12, 2020
This is version 173 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
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