SLC5A5

Functionⁱ

Mediates iodide uptake in the thyroid gland.

GO - Molecular functionⁱ

iodide transmembrane transporter activity
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 12021185
sodium:iodide symporter activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to cAMP
Source: UniProtKB
Inferred from expression patternⁱ
- 12021185
cellular response to gonadotropin stimulus
Source: UniProtKB
Inferred from expression patternⁱ
- 12021185
iodide transport
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 12021185
ion transport Source: Reactome
thyroid hormone generation Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ion transport, Sodium transport, Symport, Transport
Ligand	Sodium

Enzyme and pathway databases

Reactomeⁱ	R-HSA-209968 Thyroxine biosynthesis R-HSA-428643 Organic anion transporters R-HSA-5619096 Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)
SIGNORⁱ	Q92911

Protein family/group databases

TCDBⁱ	2.A.21.5.1 the solute:sodium symporter (sss) family

TCDBⁱ

2.A.21.5.1 the solute:sodium symporter (sss) family

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Sodium/iodide cotransporter Short name: Na(+)/I(-) cotransporter Alternative name(s): Sodium-iodide symporter Short name: Na(+)/I(-) symporter Solute carrier family 5 member 5
Gene namesⁱ	Name:SLC5A5 Synonyms:NIS
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000105641.3
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11040 SLC5A5
MIMⁱ	601843 gene
neXtProtⁱ	NX_Q92911

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 16	ExtracellularSequence analysisAdd BLAST	16
Transmembraneⁱ	17 – 37	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	38 – 53	CytoplasmicSequence analysisAdd BLAST	16
Transmembraneⁱ	54 – 74	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	75 – 88	ExtracellularSequence analysisAdd BLAST	14
Transmembraneⁱ	89 – 109	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	110 – 136	CytoplasmicSequence analysisAdd BLAST	27
Transmembraneⁱ	137 – 157	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	158 – 163	ExtracellularSequence analysis	6
Transmembraneⁱ	164 – 184	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	185 – 186	CytoplasmicSequence analysis	2
Transmembraneⁱ	187 – 207	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	208 – 241	ExtracellularSequence analysisAdd BLAST	34
Transmembraneⁱ	242 – 262	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	263 – 286	CytoplasmicSequence analysisAdd BLAST	24
Transmembraneⁱ	287 – 307	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	308 – 326	ExtracellularSequence analysisAdd BLAST	19
Transmembraneⁱ	327 – 347	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	348 – 391	CytoplasmicSequence analysisAdd BLAST	44
Transmembraneⁱ	392 – 412	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	413 – 416	ExtracellularSequence analysis	4
Transmembraneⁱ	417 – 437	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	438 – 444	CytoplasmicSequence analysis	7
Transmembraneⁱ	445 – 465	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	466 – 525	ExtracellularSequence analysisAdd BLAST	60
Transmembraneⁱ	526 – 546	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	547 – 643	CytoplasmicSequence analysisAdd BLAST	97

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Thyroid dyshormonogenesis 1 (TDH1)4 Publications

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA disorder characterized by the inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland, leading to congenital hypothyroidism.

Keywords - Diseaseⁱ

Congenital hypothyroidism, Disease mutation

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6528
MalaCards human disease database More...MalaCardsⁱ	SLC5A5
MIMⁱ	274400 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000105641
Orphanetⁱ	95716 Familial thyroid dyshormonogenesis
PharmGKBⁱ	PA35905

Polymorphism and mutation databases

BioMutaⁱ	SLC5A5
DMDMⁱ	12643359

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000105383	1 – 643	Sodium/iodide cotransporterAdd BLAST		643

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	489	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	502	N-linked (GlcNAc...) asparagineSequence analysis	1
Modified residueⁱ	556	Phosphoserine; by PKASequence analysis	1

Keywords - PTMⁱ

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbⁱ	Q92911
PeptideAtlas More...PeptideAtlasⁱ	Q92911
PRIDEⁱ	Q92911
ProteomicsDBⁱ	75594

PTM databases

iPTMnetⁱ	Q92911
PhosphoSitePlusⁱ	Q92911

Expressionⁱ

Tissue specificityⁱ

Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.2 Publications

Gene expression databases

Bgeeⁱ	ENSG00000105641 Expressed in 84 organ(s), highest expression level in thyroid gland
CleanExⁱ	HS_SLC5A5
Genevisibleⁱ	Q92911 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB022364 HPA049055

HPAⁱ

CAB022364
HPA049055

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	112419, 14 interactors
IntActⁱ	Q92911, 2 interactors
STRINGⁱ	9606.ENSP00000222248

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q92911
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG2349 Eukaryota COG0591 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118955
HOGENOMⁱ	HOG000261662
HOVERGENⁱ	HBG057280
InParanoidⁱ	Q92911
KEGG Orthology (KO) More...KOⁱ	K14385
OMAⁱ	ATFGAWD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G07OC
PhylomeDBⁱ	Q92911
TreeFamⁱ	TF316728

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd11503 SLC5sbd_NIS, 1 hit
Gene3Dⁱ	1.20.1730.10, 1 hit
InterProⁱ	View protein in InterPro IPR038377 Na/Glc_symporter_sf IPR001734 Na/solute_symporter IPR018212 Na/solute_symporter_CS IPR035689 SLC5A5
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00474 SSF, 1 hit
TIGRFAMsⁱ	TIGR00813 sss, 1 hit
PROSITEⁱ	View protein in PROSITE PS00456 NA_SOLUT_SYMP_1, 1 hit PS50283 NA_SOLUT_SYMP_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q92911-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEAVETGERP TFGAWDYGVF ALMLLVSTGI GLWVGLARGG QRSAEDFFTG 
        60         70         80         90        100
GRRLAALPVG LSLSASFMSA VQVLGVPSEA YRYGLKFLWM CLGQLLNSVL 
       110        120        130        140        150
TALLFMPVFY RLGLTSTYEY LEMRFSRAVR LCGTLQYIVA TMLYTGIVIY 
       160        170        180        190        200
APALILNQVT GLDIWASLLS TGIICTFYTA VGGMKAVVWT DVFQVVVMLS 
       210        220        230        240        250
GFWVVLARGV MLVGGPRQVL TLAQNHSRIN LMDFNPDPRS RYTFWTFVVG 
       260        270        280        290        300
GTLVWLSMYG VNQAQVQRYV ACRTEKQAKL ALLINQVGLF LIVSSAACCG 
       310        320        330        340        350
IVMFVFYTDC DPLLLGRISA PDQYMPLLVL DIFEDLPGVP GLFLACAYSG 
       360        370        380        390        400
TLSTASTSIN AMAAVTVEDL IKPRLRSLAP RKLVIISKGL SLIYGSACLT 
       410        420        430        440        450
VAALSSLLGG GVLQGSFTVM GVISGPLLGA FILGMFLPAC NTPGVLAGLG 
       460        470        480        490        500
AGLALSLWVA LGATLYPPSE QTMRVLPSSA ARCVALSVNA SGLLDPALLP 
       510        520        530        540        550
ANDSSRAPSS GMDASRPALA DSFYAISYLY YGALGTLTTV LCGALISCLT 
       560        570        580        590        600
GPTKRSTLAP GLLWWDLARQ TASVAPKEEV AILDDNLVKG PEELPTGNKK 
       610        620        630        640 
PPGFLPTNED RLFFLGQKEL EGAGSWTPCV GHDGGRDQQE TNL

Length:643

Mass (Da):68,666

Last modified:February 1, 1997 - v1

Checksum:ⁱ02D361A27B2FDA43

GO

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_010263	93	G → R in TDH1. 1 PublicationCorresponds to variant dbSNP:rs121909178EnsemblClinVar.	1
Natural variantⁱVAR_010264	102	A → P1 Publication	1
Natural variantⁱVAR_010265	267	Q → E in TDH1. 1 PublicationCorresponds to variant dbSNP:rs121909176EnsemblClinVar.	1
Natural variantⁱVAR_052490	298	C → G. Corresponds to variant dbSNP:rs8108188Ensembl.	1
Natural variantⁱVAR_010266	354	T → P in TDH1. 2 PublicationsCorresponds to variant dbSNP:rs121909174EnsemblClinVar.	1
Natural variantⁱVAR_010267	395	G → R in TDH1. 1 PublicationCorresponds to variant dbSNP:rs121909180EnsemblClinVar.	1
Natural variantⁱVAR_010268	536	T → Q Requires 2 nucleotide substitutions. 1 Publication	1
Natural variantⁱVAR_010269	543	G → E in TDH1. 1 PublicationCorresponds to variant dbSNP:rs121909179EnsemblClinVar.	1
Natural variantⁱVAR_010270	556	S → Q Requires 2 nucleotide substitutions. 1 Publication	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U66088 mRNA Translation: AAB17378.1 AC005796 Genomic DNA Translation: AAC62827.1 D87920 mRNA Translation: BAA24835.1 BC105047 mRNA Translation: AAI05048.1 BC105049 mRNA Translation: AAI05050.1 AF260700 mRNA Translation: AAF70339.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS12368.1
PIRⁱ	JC4974
NCBI Reference Sequences More...RefSeqⁱ	NP_000444.1, NM_000453.2
UniGeneⁱ	Hs.584804

Genome annotation databases

Ensemblⁱ	ENST00000222248; ENSP00000222248; ENSG00000105641
GeneIDⁱ	6528
KEGGⁱ	hsa:6528
UCSC genome browser More...UCSCⁱ	uc002nhr.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q92911	Uncharacterized protein		MACMU		655	UniRef90_Q92911
SLC5A5 isoform 1		PANTR		643
SLC5A5 isoform 1		PONAB		643
Uncharacterized protein		RHIRO		643
Uncharacterized protein		PAPAN		643
+13

Protein	Similar proteins		Species	Score	Length	Source
Q92911	Uncharacterized protein		MACMU		655	UniRef50_Q92911
SLC5A5 isoform 1		PANTR		643
SLC5A5 isoform 1		PONAB		643
Uncharacterized protein		PAPAN		643
Uncharacterized protein		RHIRO		643
+116

Cross-referencesⁱ

Web resourcesⁱ

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U66088 mRNA Translation: AAB17378.1 AC005796 Genomic DNA Translation: AAC62827.1 D87920 mRNA Translation: BAA24835.1 BC105047 mRNA Translation: AAI05048.1 BC105049 mRNA Translation: AAI05050.1 AF260700 mRNA Translation: AAF70339.1
CCDSⁱ	CCDS12368.1
PIRⁱ	JC4974
RefSeqⁱ	NP_000444.1, NM_000453.2
UniGeneⁱ	Hs.584804

3D structure databases

ProteinModelPortalⁱ	Q92911
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112419, 14 interactors
IntActⁱ	Q92911, 2 interactors
STRINGⁱ	9606.ENSP00000222248

Protein family/group databases

TCDBⁱ	2.A.21.5.1 the solute:sodium symporter (sss) family

TCDBⁱ

2.A.21.5.1 the solute:sodium symporter (sss) family

PTM databases

iPTMnetⁱ	Q92911
PhosphoSitePlusⁱ	Q92911

Polymorphism and mutation databases

BioMutaⁱ	SLC5A5
DMDMⁱ	12643359

Proteomic databases

PaxDbⁱ	Q92911
PeptideAtlasⁱ	Q92911
PRIDEⁱ	Q92911
ProteomicsDBⁱ	75594

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000222248; ENSP00000222248; ENSG00000105641
GeneIDⁱ	6528
KEGGⁱ	hsa:6528
UCSCⁱ	uc002nhr.4 human

Organism-specific databases

CTDⁱ	6528
DisGeNETⁱ	6528
EuPathDBⁱ	HostDB:ENSG00000105641.3
GeneCardsⁱ	SLC5A5
HGNCⁱ	HGNC:11040 SLC5A5
HPAⁱ	CAB022364 HPA049055
MalaCardsⁱ	SLC5A5
MIMⁱ	274400 phenotype 601843 gene
neXtProtⁱ	NX_Q92911
OpenTargetsⁱ	ENSG00000105641
Orphanetⁱ	95716 Familial thyroid dyshormonogenesis
PharmGKBⁱ	PA35905
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2349 Eukaryota COG0591 LUCA
GeneTreeⁱ	ENSGT00760000118955
HOGENOMⁱ	HOG000261662
HOVERGENⁱ	HBG057280
InParanoidⁱ	Q92911
KOⁱ	K14385
OMAⁱ	ATFGAWD
OrthoDBⁱ	EOG091G07OC
PhylomeDBⁱ	Q92911
TreeFamⁱ	TF316728

Enzyme and pathway databases

Reactomeⁱ	R-HSA-209968 Thyroxine biosynthesis R-HSA-428643 Organic anion transporters R-HSA-5619096 Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)
SIGNORⁱ	Q92911

Miscellaneous databases

ChiTaRSⁱ	SLC5A5 human
GeneWikiⁱ	Sodium-iodide_symporter
GenomeRNAiⁱ	6528
Protein Ontology More...PROⁱ	PR:Q92911
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000105641 Expressed in 84 organ(s), highest expression level in thyroid gland
CleanExⁱ	HS_SLC5A5
Genevisibleⁱ	Q92911 HS

Family and domain databases

CDDⁱ	cd11503 SLC5sbd_NIS, 1 hit
Gene3Dⁱ	1.20.1730.10, 1 hit
InterProⁱ	View protein in InterPro IPR038377 Na/Glc_symporter_sf IPR001734 Na/solute_symporter IPR018212 Na/solute_symporter_CS IPR035689 SLC5A5
Pfamⁱ	View protein in Pfam PF00474 SSF, 1 hit
TIGRFAMsⁱ	TIGR00813 sss, 1 hit
PROSITEⁱ	View protein in PROSITE PS00456 NA_SOLUT_SYMP_1, 1 hit PS50283 NA_SOLUT_SYMP_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SC5A5_HUMAN
Accessionⁱ	Q92911Primary (citable) accession number: Q92911 Secondary accession number(s): O43702, Q2M335, Q9NYB6
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
	Last sequence update:	February 1, 1997
	Last modified:	November 7, 2018
	This is version 169 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM

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UniProtKB - Q92911 (SC5A5_HUMAN)

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Sodium/iodide cotransporter

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Extracellular region or secreted

Nucleus

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ