UniProtKB - Q92854 (SEM4D_HUMAN)
Protein
Semaphorin-4D
Gene
SEMA4D
Organism
Homo sapiens (Human)
Status
Functioni
Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed:20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed:19788569). Promotes the migration of cerebellar granule cells (PubMed:16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed:8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed:16055703).By similarity4 Publications
GO - Molecular functioni
- chemorepellent activity Source: GO_Central
- identical protein binding Source: IntAct
- semaphorin receptor binding Source: UniProtKB
- signaling receptor activity Source: HGNC-UCL
- signaling receptor binding Source: UniProtKB
- transmembrane signaling receptor activity Source: UniProtKB
GO - Biological processi
- axon guidance Source: GO_Central
- cell adhesion Source: ProtInc
- immune response Source: ProtInc
- leukocyte aggregation Source: UniProtKB
- negative chemotaxis Source: GO_Central
- negative regulation of alkaline phosphatase activity Source: BHF-UCL
- negative regulation of apoptotic process Source: ProtInc
- negative regulation of axon extension involved in axon guidance Source: GO_Central
- negative regulation of cell adhesion Source: UniProtKB
- negative regulation of osteoblast differentiation Source: BHF-UCL
- negative regulation of peptidyl-tyrosine phosphorylation Source: BHF-UCL
- negative regulation of transcription by RNA polymerase II Source: BHF-UCL
- neural crest cell migration Source: GO_Central
- ossification involved in bone maturation Source: BHF-UCL
- positive regulation of cell migration Source: UniProtKB
- positive regulation of collateral sprouting Source: UniProtKB
- positive regulation of GTPase activity Source: UniProtKB
- positive regulation of inhibitory synapse assembly Source: UniProtKB
- positive regulation of peptidyl-tyrosine phosphorylation Source: BHF-UCL
- positive regulation of phosphatidylinositol 3-kinase signaling Source: UniProtKB
- positive regulation of protein phosphorylation Source: UniProtKB
- regulation of cell projection organization Source: UniProtKB
- regulation of cell shape Source: UniProtKB
- regulation of dendrite morphogenesis Source: UniProtKB
- semaphorin-plexin signaling pathway Source: UniProtKB
- semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis Source: BHF-UCL
Keywordsi
Molecular function | Developmental protein, Receptor |
Biological process | Differentiation, Neurogenesis |
Enzyme and pathway databases
PathwayCommonsi | Q92854 |
Reactomei | R-HSA-416550, Sema4D mediated inhibition of cell attachment and migration R-HSA-416572, Sema4D induced cell migration and growth-cone collapse R-HSA-416700, Other semaphorin interactions |
SIGNORi | Q92854 |
Names & Taxonomyi
Protein namesi | Recommended name: Semaphorin-4DAlternative name(s): A8 BB18 GR3 CD_antigen: CD100 |
Gene namesi | Name:SEMA4D Synonyms:C9orf164, CD100, SEMAJ |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:10732, SEMA4D |
MIMi | 601866, gene |
neXtProti | NX_Q92854 |
VEuPathDBi | HostDB:ENSG00000187764.11 |
Subcellular locationi
Plasma membrane
- Cell membrane 2 Publications; Single-pass type I membrane protein Sequence analysis
Extracellular region or secreted
- extracellular space Source: BHF-UCL
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB
- plasma membrane Source: Reactome
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 22 – 734 | ExtracellularSequence analysisAdd BLAST | 713 | |
Transmembranei | 735 – 755 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 756 – 862 | CytoplasmicSequence analysisAdd BLAST | 107 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 100 – 101 | KG → DT: Abolishes PLXNB1 binding. 1 Publication | 2 | |
Mutagenesisi | 181 – 182 | FL → ER: Abolishes PLXNB1 binding. 1 Publication | 2 | |
Mutagenesisi | 244 | F → N: Abolishes homodimerization, abolishes collapse of growth cones and reduces PLXNB1 binding; when associated with S-246. 1 Publication | 1 | |
Mutagenesisi | 246 | F → S: Abolishes homodimerization, abolishes collapse of growth cones and reduces PLXNB1 binding; when associated with N-244. 1 Publication | 1 | |
Mutagenesisi | 395 | K → E: Strongly reduces PLXNB1 binding. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 10507 |
OpenTargetsi | ENSG00000187764 |
PharmGKBi | PA35654 |
Miscellaneous databases
Pharosi | Q92854, Tbio |
Chemistry databases
GuidetoPHARMACOLOGYi | 2883 |
Genetic variation databases
BioMutai | SEMA4D |
DMDMi | 8134701 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_0000032327 | 22 – 862 | Semaphorin-4DAdd BLAST | 841 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 49 | N-linked (GlcNAc...) asparagine2 Publications | 1 | |
Glycosylationi | 77 | N-linked (GlcNAc...) asparagine2 Publications | 1 | |
Disulfide bondi | 97 ↔ 108 | |||
Disulfide bondi | 126 ↔ 135 | |||
Glycosylationi | 139 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 191 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Disulfide bondi | 257 ↔ 370 | |||
Disulfide bondi | 281 ↔ 326 | |||
Glycosylationi | 329 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 379 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 419 | N-linked (GlcNAc...) asparagine3 Publications | 1 | |
Disulfide bondi | 503 ↔ 520 | |||
Disulfide bondi | 509 ↔ 553 | |||
Disulfide bondi | 512 ↔ 529 | |||
Disulfide bondi | 576 ↔ 624 | |||
Glycosylationi | 613 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 632 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 833 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
EPDi | Q92854 |
jPOSTi | Q92854 |
MassIVEi | Q92854 |
MaxQBi | Q92854 |
PaxDbi | Q92854 |
PeptideAtlasi | Q92854 |
PRIDEi | Q92854 |
ProteomicsDBi | 75549 [Q92854-1] 75550 [Q92854-2] |
PTM databases
GlyConnecti | 1734, 13 N-Linked glycans (4 sites) |
GlyGeni | Q92854, 12 sites, 1 O-linked glycan (2 sites) |
iPTMneti | Q92854 |
PhosphoSitePlusi | Q92854 |
SwissPalmi | Q92854 |
Expressioni
Tissue specificityi
Strongly expressed in skeletal muscle, peripheral blood lymphocytes, spleen, and thymus and also expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver.1 Publication
Gene expression databases
Bgeei | ENSG00000187764, Expressed in C1 segment of cervical spinal cord and 223 other tissues |
ExpressionAtlasi | Q92854, baseline and differential |
Genevisiblei | Q92854, HS |
Organism-specific databases
HPAi | ENSG00000187764, Tissue enhanced (brain, skeletal muscle) |
Interactioni
Subunit structurei
Binary interactionsi
Hide detailsSEMA4D - isoform 1 [Q92854-1]
With | #Exp. | IntAct |
---|---|---|
PLXNB1 - isoform 1 [O43157-1] | 3 | EBI-15880903,EBI-15880891 |
itself | 3 | EBI-15880903,EBI-15880903 |
GO - Molecular functioni
- chemorepellent activity Source: GO_Central
- identical protein binding Source: IntAct
- semaphorin receptor binding Source: UniProtKB
- signaling receptor binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 115766, 18 interactors |
CORUMi | Q92854 |
DIPi | DIP-59221N |
IntActi | Q92854, 8 interactors |
MINTi | Q92854 |
STRINGi | 9606.ENSP00000416523 |
Miscellaneous databases
RNActi | Q92854, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q92854 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q92854 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 22 – 500 | SemaPROSITE-ProRule annotationAdd BLAST | 479 | |
Domaini | 502 – 551 | PSIAdd BLAST | 50 | |
Domaini | 554 – 636 | Ig-like C2-typeAdd BLAST | 83 |
Sequence similaritiesi
Belongs to the semaphorin family.Curated
Keywords - Domaini
Immunoglobulin domain, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG3611, Eukaryota |
GeneTreei | ENSGT00940000159594 |
HOGENOMi | CLU_009051_4_0_1 |
InParanoidi | Q92854 |
OMAi | CAWKPLE |
OrthoDBi | 64683at2759 |
PhylomeDBi | Q92854 |
TreeFami | TF316102 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013151, Immunoglobulin IPR002165, Plexin_repeat IPR016201, PSI IPR001627, Semap_dom IPR036352, Semap_dom_sf IPR027231, Semaphorin IPR015943, WD40/YVTN_repeat-like_dom_sf |
PANTHERi | PTHR11036, PTHR11036, 1 hit |
Pfami | View protein in Pfam PF00047, ig, 1 hit PF01437, PSI, 1 hit PF01403, Sema, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00408, IGc2, 1 hit SM00423, PSI, 1 hit SM00630, Sema, 1 hit |
SUPFAMi | SSF101912, SSF101912, 1 hit SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS51004, SEMA, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q92854-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MRMCTPIRGL LMALAVMFGT AMAFAPIPRI TWEHREVHLV QFHEPDIYNY
60 70 80 90 100
SALLLSEDKD TLYIGAREAV FAVNALNISE KQHEVYWKVS EDKKAKCAEK
110 120 130 140 150
GKSKQTECLN YIRVLQPLSA TSLYVCGTNA FQPACDHLNL TSFKFLGKNE
160 170 180 190 200
DGKGRCPFDP AHSYTSVMVD GELYSGTSYN FLGSEPIISR NSSHSPLRTE
210 220 230 240 250
YAIPWLNEPS FVFADVIRKS PDSPDGEDDR VYFFFTEVSV EYEFVFRVLI
260 270 280 290 300
PRIARVCKGD QGGLRTLQKK WTSFLKARLI CSRPDSGLVF NVLRDVFVLR
310 320 330 340 350
SPGLKVPVFY ALFTPQLNNV GLSAVCAYNL STAEEVFSHG KYMQSTTVEQ
360 370 380 390 400
SHTKWVRYNG PVPKPRPGAC IDSEARAANY TSSLNLPDKT LQFVKDHPLM
410 420 430 440 450
DDSVTPIDNR PRLIKKDVNY TQIVVDRTQA LDGTVYDVMF VSTDRGALHK
460 470 480 490 500
AISLEHAVHI IEETQLFQDF EPVQTLLLSS KKGNRFVYAG SNSGVVQAPL
510 520 530 540 550
AFCGKHGTCE DCVLARDPYC AWSPPTATCV ALHQTESPSR GLIQEMSGDA
560 570 580 590 600
SVCPDKSKGS YRQHFFKHGG TAELKCSQKS NLARVFWKFQ NGVLKAESPK
610 620 630 640 650
YGLMGRKNLL IFNLSEGDSG VYQCLSEERV KNKTVFQVVA KHVLEVKVVP
660 670 680 690 700
KPVVAPTLSV VQTEGSRIAT KVLVASTQGS SPPTPAVQAT SSGAITLPPK
710 720 730 740 750
PAPTGTSCEP KIVINTVPQL HSEKTMYLKS SDNRLLMSLF LFFFVLFLCL
760 770 780 790 800
FFYNCYKGYL PRQCLKFRSA LLIGKKKPKS DFCDREQSLK ETLVEPGSFS
810 820 830 840 850
QQNGEHPKPA LDTGYETEQD TITSKVPTDR EDSQRIDDLS ARDKPFDVKC
860
ELKFADSDAD GD
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9JFP1 | C9JFP1_HUMAN | Semaphorin-4D | SEMA4D | 146 | Annotation score: | ||
E9PFD9 | E9PFD9_HUMAN | Semaphorin-4D | SEMA4D | 548 | Annotation score: | ||
C9JYS7 | C9JYS7_HUMAN | Semaphorin-4D | SEMA4D | 75 | Annotation score: | ||
F5H044 | F5H044_HUMAN | Semaphorin-4D | SEMA4D | 66 | Annotation score: | ||
C9JD54 | C9JD54_HUMAN | Semaphorin-4D | SEMA4D | 59 | Annotation score: | ||
A0A0C4DG45 | A0A0C4DG45_HUMAN | Semaphorin-4D | SEMA4D | 123 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 592 | G → D in AAH54500 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_030293 | 72 | A → T. Corresponds to variant dbSNP:rs13284404Ensembl. | 1 | |
Natural variantiVAR_057175 | 327 | A → T. Corresponds to variant dbSNP:rs11526468Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_039483 | 555 – 738 | DKSKG…RLLMS → ASSPKPLPPPGSSSLSCLGH VGDRRLSSPWTPWPASGAGP DSSSRVSLLPPFLSDQAQHV HALGNFYLFCQATGPADIRF VWEKNGRALETCVPVQTHAL PDGRAHALSWLQDAIRESAE YRCSVLSSAGNKTSKVQVAV MRPEVTHQERWTRELSAWRA VAGEHDRMMQSWRKAWESCS KDTL in isoform 2. CuratedAdd BLAST | 184 | |
Alternative sequenceiVSP_039484 | 739 – 862 | Missing in isoform 2. CuratedAdd BLAST | 124 |
Sequence databases
Genome annotation databases
Ensembli | ENST00000339861; ENSP00000344923; ENSG00000187764 [Q92854-2] ENST00000356444; ENSP00000348822; ENSG00000187764 [Q92854-1] ENST00000420987; ENSP00000391733; ENSG00000187764 [Q92854-2] ENST00000422704; ENSP00000388768; ENSG00000187764 [Q92854-1] ENST00000438547; ENSP00000405102; ENSG00000187764 [Q92854-1] ENST00000450295; ENSP00000416523; ENSG00000187764 [Q92854-1] ENST00000455551; ENSP00000411981; ENSG00000187764 [Q92854-2] |
GeneIDi | 10507 |
KEGGi | hsa:10507 |
UCSCi | uc004aqo.2, human [Q92854-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
Atlas of Genetics and Cytogenetics in Oncology and Haematology |
Sequence databases
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1OLZ | X-ray | 2.00 | A/B | 22-677 | [»] | |
3OL2 | X-ray | 2.99 | A | 22-677 | [»] | |
SMRi | Q92854 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 115766, 18 interactors |
CORUMi | Q92854 |
DIPi | DIP-59221N |
IntActi | Q92854, 8 interactors |
MINTi | Q92854 |
STRINGi | 9606.ENSP00000416523 |
Chemistry databases
GuidetoPHARMACOLOGYi | 2883 |
PTM databases
GlyConnecti | 1734, 13 N-Linked glycans (4 sites) |
GlyGeni | Q92854, 12 sites, 1 O-linked glycan (2 sites) |
iPTMneti | Q92854 |
PhosphoSitePlusi | Q92854 |
SwissPalmi | Q92854 |
Genetic variation databases
BioMutai | SEMA4D |
DMDMi | 8134701 |
Proteomic databases
EPDi | Q92854 |
jPOSTi | Q92854 |
MassIVEi | Q92854 |
MaxQBi | Q92854 |
PaxDbi | Q92854 |
PeptideAtlasi | Q92854 |
PRIDEi | Q92854 |
ProteomicsDBi | 75549 [Q92854-1] 75550 [Q92854-2] |
Protocols and materials databases
ABCDi | Q92854, 20 sequenced antibodies |
Antibodypediai | 3064, 880 antibodies |
Genome annotation databases
Organism-specific databases
CTDi | 10507 |
DisGeNETi | 10507 |
GeneCardsi | SEMA4D |
HGNCi | HGNC:10732, SEMA4D |
HPAi | ENSG00000187764, Tissue enhanced (brain, skeletal muscle) |
MIMi | 601866, gene |
neXtProti | NX_Q92854 |
OpenTargetsi | ENSG00000187764 |
PharmGKBi | PA35654 |
VEuPathDBi | HostDB:ENSG00000187764.11 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3611, Eukaryota |
GeneTreei | ENSGT00940000159594 |
HOGENOMi | CLU_009051_4_0_1 |
InParanoidi | Q92854 |
OMAi | CAWKPLE |
OrthoDBi | 64683at2759 |
PhylomeDBi | Q92854 |
TreeFami | TF316102 |
Enzyme and pathway databases
PathwayCommonsi | Q92854 |
Reactomei | R-HSA-416550, Sema4D mediated inhibition of cell attachment and migration R-HSA-416572, Sema4D induced cell migration and growth-cone collapse R-HSA-416700, Other semaphorin interactions |
SIGNORi | Q92854 |
Miscellaneous databases
BioGRID-ORCSi | 10507, 3 hits in 874 CRISPR screens |
ChiTaRSi | SEMA4D, human |
EvolutionaryTracei | Q92854 |
GeneWikii | SEMA4D |
GenomeRNAii | 10507 |
Pharosi | Q92854, Tbio |
PROi | PR:Q92854 |
RNActi | Q92854, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000187764, Expressed in C1 segment of cervical spinal cord and 223 other tissues |
ExpressionAtlasi | Q92854, baseline and differential |
Genevisiblei | Q92854, HS |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit 2.60.40.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013151, Immunoglobulin IPR002165, Plexin_repeat IPR016201, PSI IPR001627, Semap_dom IPR036352, Semap_dom_sf IPR027231, Semaphorin IPR015943, WD40/YVTN_repeat-like_dom_sf |
PANTHERi | PTHR11036, PTHR11036, 1 hit |
Pfami | View protein in Pfam PF00047, ig, 1 hit PF01437, PSI, 1 hit PF01403, Sema, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00408, IGc2, 1 hit SM00423, PSI, 1 hit SM00630, Sema, 1 hit |
SUPFAMi | SSF101912, SSF101912, 1 hit SSF48726, SSF48726, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS51004, SEMA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SEM4D_HUMAN | |
Accessioni | Q92854Primary (citable) accession number: Q92854 Secondary accession number(s): B2RPM6, Q7Z5S4, Q8N8B0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | February 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 209 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM - Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries