UniProtKB - Q92833 (JARD2_HUMAN)
Protein Jumonji
JARID2
Functioni
Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis (PubMed:20075857).
Acts as an accessory subunit for the core PRC2 (Polycomb repressive complex 2) complex, which mediates histone H3K27 (H3K27me3) trimethylation on chromatin (PubMed:20075857, PubMed:29499137, PubMed:31959557).
Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, thereby playing a key role in stem cell differentiation and normal embryonic development (PubMed:20075857).
In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases (By similarity).
Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5 (By similarity).
Participates in the negative regulation of cell proliferation signaling (By similarity).
Does not have histone demethylase activity (By similarity).
By similarity3 PublicationsGO - Molecular functioni
- chromatin binding Source: UniProtKB
- DNA binding Source: Ensembl
- histone demethylase activity Source: GO_Central
- ubiquitin binding Source: Ensembl
- ubiquitin modification-dependent histone binding Source: Ensembl
GO - Biological processi
- cellular response to leukemia inhibitory factor Source: Ensembl
- central nervous system development Source: ProtInc
- chromatin remodeling Source: GO_Central
- dosage compensation by inactivation of X chromosome Source: Ensembl
- liver development Source: Ensembl
- negative regulation of cardiac muscle cell proliferation Source: Ensembl
- negative regulation of cardiac muscle hypertrophy Source: Ensembl
- negative regulation of histone methylation Source: UniProtKB
- negative regulation of transcription, DNA-templated Source: UniProtKB
- negative regulation of transcription by RNA polymerase II Source: Ensembl
- positive regulation of histone H3-K9 methylation Source: UniProtKB
- protein localization to pericentric heterochromatin Source: Ensembl
- spleen development Source: Ensembl
- stem cell differentiation Source: UniProtKB
- thymus development Source: Ensembl
Keywordsi
Molecular function | Chromatin regulator, Developmental protein, Repressor |
Biological process | Differentiation, Transcription, Transcription regulation |
Enzyme and pathway databases
PathwayCommonsi | Q92833 |
Reactomei | R-HSA-212300, PRC2 methylates histones and DNA |
SignaLinki | Q92833 |
SIGNORi | Q92833 |
Names & Taxonomyi
Protein namesi | Recommended name: Protein JumonjiAlternative name(s): Jumonji/ARID domain-containing protein 2 |
Gene namesi | Name:JARID2 Synonyms:JMJ |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:6196, JARID2 |
MIMi | 601594, gene |
neXtProti | NX_Q92833 |
VEuPathDBi | HostDB:ENSG00000008083 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation2 Publications
Note: Colocalizes with the PRC2 complex on chromatin.1 Publication
Mitochondrion
- mitochondrion Source: HPA
Nucleus
- ESC/E(Z) complex Source: Ensembl
- histone methyltransferase complex Source: UniProtKB
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Keywords - Cellular componenti
NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 149 – 150 | KR → DE or AA: Abolishes nucleosome binding activity of a minimal SUZ12-RBBP4-AEBP2-JARID2 PRC2 complex. 1 Publication | 2 | |
Mutagenesisi | 151 – 153 | KPK → EPE or APA: Abolishes nucleosome binding activity of a minimal SUZ12-RBBP4-AEBP2-JARID2 PRC2 complex. 1 Publication | 3 |
Organism-specific databases
DisGeNETi | 3720 |
OpenTargetsi | ENSG00000008083 |
Orphaneti | 528084, Non-specific syndromic intellectual disability |
PharmGKBi | PA29995 |
Miscellaneous databases
Pharosi | Q92833, Tbio |
Genetic variation databases
BioMutai | JARID2 |
DMDMi | 61252601 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000200591 | 1 – 1246 | Protein JumonjiAdd BLAST | 1246 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 78 | PhosphoserineCombined sources | 1 | |
Modified residuei | 378 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 455 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
EPDi | Q92833 |
jPOSTi | Q92833 |
MassIVEi | Q92833 |
MaxQBi | Q92833 |
PaxDbi | Q92833 |
PeptideAtlasi | Q92833 |
PRIDEi | Q92833 |
ProteomicsDBi | 6958 75511 [Q92833-1] 75512 [Q92833-2] |
PTM databases
iPTMneti | Q92833 |
PhosphoSitePlusi | Q92833 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000008083, Expressed in secondary oocyte and 250 other tissues |
Genevisiblei | Q92833, HS |
Organism-specific databases
HPAi | ENSG00000008083, Tissue enhanced (bone) |
Interactioni
Subunit structurei
Associates with the PRC2 complex, which consists of the core components EED, EZH1 or EZH2, SUZ12, and RBBP4, and various combinations of accessory subunits including AEBP2, JARID2, PHF19, MTF2 and EPOP (PubMed:29499137, PubMed:31959557).
Found in a monomeric PRC2.2 (class 2) complex consisting of at least SUZ12, RBBP4, AEBP2 and JARID2 (PubMed:29499137). Faciliates nucleosome binding of the PRC2 complex (PubMed:29499137).
Interacts with SUZ12 (via C2H2-type zinc finger domain); the interaction is direct; competes with EPOP for SUZ12 binding (PubMed:29499137).
Interacts with histone methyltransferases EHMT1/GLP1 and EHMT2/G9a (By similarity).
Interacts with GATA4 (via the N-terminal region) (By similarity).
Interacts with NKX2-5 (via the C-terminal region) (By similarity).
Interacts with RB1 (By similarity).
Interacts with ZNF496 (By similarity).
Interacts with ESRRB (By similarity).
By similarity2 PublicationsBinary interactionsi
Isoform 1 [Q92833-1]
With | #Exp. | IntAct |
---|---|---|
EED [O75530] | 4 | EBI-15825247,EBI-923794 |
EZH2 [Q15910] | 7 | EBI-15825247,EBI-530054 |
SUZ12 [Q15022] | 7 | EBI-15825247,EBI-1264675 |
GO - Molecular functioni
- ubiquitin binding Source: Ensembl
- ubiquitin modification-dependent histone binding Source: Ensembl
Protein-protein interaction databases
BioGRIDi | 109923, 37 interactors |
DIPi | DIP-45494N |
IntActi | Q92833, 26 interactors |
MINTi | Q92833 |
STRINGi | 9606.ENSP00000341280 |
Miscellaneous databases
RNActi | Q92833, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q92833 |
BMRBi | Q92833 |
SMRi | Q92833 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 557 – 598 | JmjNPROSITE-ProRule annotationAdd BLAST | 42 | |
Domaini | 621 – 713 | ARIDPROSITE-ProRule annotationAdd BLAST | 93 | |
Domaini | 884 – 1048 | JmjCPROSITE-ProRule annotationAdd BLAST | 165 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 22 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 59 – 150 | DisorderedSequence analysisAdd BLAST | 92 | |
Regioni | 141 – 170 | Sufficient for interaction with the PRC2 complex1 PublicationAdd BLAST | 30 | |
Regioni | 169 – 299 | DisorderedSequence analysisAdd BLAST | 131 | |
Regioni | 357 – 548 | DisorderedSequence analysisAdd BLAST | 192 | |
Regioni | 1208 – 1246 | DisorderedSequence analysisAdd BLAST | 39 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 104 – 110 | Nuclear localization signalBy similarity | 7 | |
Motifi | 874 – 878 | GSGFP motif | 5 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 60 – 75 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 84 – 99 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 114 – 130 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 180 – 194 | Acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 229 – 264 | Basic and acidic residuesSequence analysisAdd BLAST | 36 | |
Compositional biasi | 367 – 399 | Polar residuesSequence analysisAdd BLAST | 33 | |
Compositional biasi | 427 – 455 | Basic and acidic residuesSequence analysisAdd BLAST | 29 | |
Compositional biasi | 479 – 502 | Basic and acidic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 519 – 535 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1230 – 1246 | Polar residuesSequence analysisAdd BLAST | 17 |
Domaini
Phylogenomic databases
eggNOGi | KOG1246, Eukaryota |
GeneTreei | ENSGT00940000159220 |
HOGENOMi | CLU_007086_0_0_1 |
InParanoidi | Q92833 |
OMAi | VFNGSNR |
OrthoDBi | 664180at2759 |
PhylomeDBi | Q92833 |
TreeFami | TF323264 |
Family and domain databases
Gene3Di | 1.10.150.60, 1 hit |
InterProi | View protein in InterPro IPR001606, ARID_dom IPR036431, ARID_dom_sf IPR003347, JmjC_dom IPR003349, JmjN IPR004198, Znf_C5HC2 |
Pfami | View protein in Pfam PF01388, ARID, 1 hit PF02373, JmjC, 1 hit PF02375, JmjN, 1 hit PF02928, zf-C5HC2, 1 hit |
SMARTi | View protein in SMART SM00501, BRIGHT, 1 hit SM00558, JmjC, 1 hit SM00545, JmjN, 1 hit |
SUPFAMi | SSF46774, SSF46774, 1 hit |
PROSITEi | View protein in PROSITE PS51011, ARID, 1 hit PS51184, JMJC, 1 hit PS51183, JMJN, 1 hit |
s (3)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MSKERPKRNI IQKKYDDSDG IPWSEERVVR KVLYLSLKEF KNSQKRQHAE
60 70 80 90 100
GIAGSLKTVN GLLGNDQSKG LGPASEQSEN EKDDASQVSS TSNDVSSSDF
110 120 130 140 150
EEGPSRKRPR LQAQRKFAQS QPNSPSTTPV KIVEPLLPPP ATQISDLSKR
160 170 180 190 200
KPKTEDFLTF LCLRGSPALP NSMVYFGSSQ DEEEVEEEDD ETEDVKTATN
210 220 230 240 250
NASSSCQSTP RKGKTHKHVH NGHVFNGSSR STREKEPVQK HKSKEATPAK
260 270 280 290 300
EKHSDHRADS RREQASANHP AAAPSTGSSA KGLAATHHHP PLHRSAQDLR
310 320 330 340 350
KQVSKVNGVT RMSSLGAGVT SAKKMREVRP SPSKTVKYTA TVTKGAVTYT
360 370 380 390 400
KAKRELVKDT KPNHHKPSSA VNHTISGKTE SSNAKTRKQV LSLGGASKST
410 420 430 440 450
GPAVNGLKVS GRLNPKSCTK EVGGRQLREG LQLREGLRNS KRRLEEAHQA
460 470 480 490 500
EKPQSPPKKM KGAAGPAEGP GKKAPAERGL LNGHVKKEVP ERSLERNRPK
510 520 530 540 550
RATAGKSTPG RQAHGKADSA SCENRSTSQP ESVHKPQDSG KAEKGGGKAG
560 570 580 590 600
WAAMDEIPVL RPSAKEFHDP LIYIESVRAQ VEKFGMCRVI PPPDWRPECK
610 620 630 640 650
LNDEMRFVTQ IQHIHKLGRR WGPNVQRLAC IKKHLKSQGI TMDELPLIGG
660 670 680 690 700
CELDLACFFR LINEMGGMQQ VTDLKKWNKL ADMLRIPRTA QDRLAKLQEA
710 720 730 740 750
YCQYLLSYDS LSPEEHRRLE KEVLMEKEIL EKRKGPLEGH TENDHHKFHP
760 770 780 790 800
LPRFEPKNGL IHGVAPRNGF RSKLKEVGQA QLKTGRRRLF AQEKEVVKEE
810 820 830 840 850
EEDKGVLNDF HKCIYKGRSV SLTTFYRTAR NIMSMCFSKE PAPAEIEQEY
860 870 880 890 900
WRLVEEKDCH VAVHCGKVDT NTHGSGFPVG KSEPFSRHGW NLTVLPNNTG
910 920 930 940 950
SILRHLGAVP GVTIPWLNIG MVFSTSCWSR DQNHLPYIDY LHTGADCIWY
960 970 980 990 1000
CIPAEEENKL EDVVHTLLQA NGTPGLQMLE SNVMISPEVL CKEGIKVHRT
1010 1020 1030 1040 1050
VQQSGQFVVC FPGSFVSKVC CGYSVSETVH FATTQWTSMG FETAKEMKRR
1060 1070 1080 1090 1100
HIAKPFSMEK LLYQIAQAEA KKENGPTLST ISALLDELRD TELRQRRQLF
1110 1120 1130 1140 1150
EAGLHSSARY GSHDGSSTVA DGKKKPRKWL QLETSERRCQ ICQHLCYLSM
1160 1170 1180 1190 1200
VVQENENVVF CLECALRHVE KQKSCRGLKL MYRYDEEQII SLVNQICGKV
1210 1220 1230 1240
SGKNGSIENC LSKPTPKRGP RKRATVDVPP SRLSASSSSK SASSSS
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 250 | K → E in BAH13011 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 599 | C → S in BAH13011 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 673 | D → E in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 681 | A → S in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 688 | R → K in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 692 | D → E in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 705 | L → I in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 754 | F → L in AAC50822 (PubMed:8894700).Curated | 1 | |
Sequence conflicti | 1212 | S → H in AAC50822 (PubMed:8894700).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_045041 | 1 – 172 | Missing in isoform 3. 1 PublicationAdd BLAST | 172 | |
Alternative sequenceiVSP_038756 | 1 – 60 | MSKER…LKTVN → MAAPRVCQVQFLVAYLEEPG IE in isoform 2. 1 PublicationAdd BLAST | 60 | |
Alternative sequenceiVSP_038757 | 949 – 1246 | WYCIP…ASSSS → CLSVEPVFPHLSVAVGSIVD LGISFLPCGDTRVMYPVESV AWRGVLGPRL in isoform 2. 1 PublicationAdd BLAST | 298 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57592 mRNA Translation: AAC50822.1 Frameshift. AK292861 mRNA Translation: BAF85550.1 AK299349 mRNA Translation: BAH13011.1 AK303610 mRNA Translation: BAH13996.1 AL021938 Genomic DNA No translation available. AL136162 Genomic DNA No translation available. CH471087 Genomic DNA Translation: EAW55357.1 BC046184 mRNA Translation: AAH46184.1 BC046246 mRNA Translation: AAH46246.1 |
CCDSi | CCDS4533.1 [Q92833-1] CCDS58996.1 [Q92833-3] |
RefSeqi | NP_001253969.1, NM_001267040.1 [Q92833-3] NP_004964.2, NM_004973.3 [Q92833-1] XP_005249146.1, XM_005249089.3 XP_016866323.1, XM_017010834.1 [Q92833-3] XP_016866324.1, XM_017010835.1 [Q92833-3] |
Genome annotation databases
Ensembli | ENST00000341776.7; ENSP00000341280.2; ENSG00000008083.14 ENST00000397311.4; ENSP00000380478.3; ENSG00000008083.14 [Q92833-3] |
GeneIDi | 3720 |
KEGGi | hsa:3720 |
MANE-Selecti | ENST00000341776.7; ENSP00000341280.2; NM_004973.4; NP_004964.2 |
UCSCi | uc003nbj.5, human [Q92833-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U57592 mRNA Translation: AAC50822.1 Frameshift. AK292861 mRNA Translation: BAF85550.1 AK299349 mRNA Translation: BAH13011.1 AK303610 mRNA Translation: BAH13996.1 AL021938 Genomic DNA No translation available. AL136162 Genomic DNA No translation available. CH471087 Genomic DNA Translation: EAW55357.1 BC046184 mRNA Translation: AAH46184.1 BC046246 mRNA Translation: AAH46246.1 |
CCDSi | CCDS4533.1 [Q92833-1] CCDS58996.1 [Q92833-3] |
RefSeqi | NP_001253969.1, NM_001267040.1 [Q92833-3] NP_004964.2, NM_004973.3 [Q92833-1] XP_005249146.1, XM_005249089.3 XP_016866323.1, XM_017010834.1 [Q92833-3] XP_016866324.1, XM_017010835.1 [Q92833-3] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5HYN | X-ray | 2.95 | E/J/P/U | 110-121 | [»] | |
5LS6 | X-ray | 3.47 | Q/R/S/T | 110-120 | [»] | |
5WAI | X-ray | 2.90 | D/H | 147-165 | [»] | |
6C23 | electron microscopy | 3.90 | B/E | 106-450 | [»] | |
6C24 | electron microscopy | 3.50 | B/E | 106-450 | [»] | |
6NQ3 | X-ray | 2.89 | D/H | 147-165 | [»] | |
6WKR | electron microscopy | 3.50 | B/E | 1-450 | [»] | |
7KSO | electron microscopy | 3.90 | F | 1-1246 | [»] | |
AlphaFoldDBi | Q92833 | |||||
BMRBi | Q92833 | |||||
SMRi | Q92833 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 109923, 37 interactors |
DIPi | DIP-45494N |
IntActi | Q92833, 26 interactors |
MINTi | Q92833 |
STRINGi | 9606.ENSP00000341280 |
PTM databases
iPTMneti | Q92833 |
PhosphoSitePlusi | Q92833 |
Genetic variation databases
BioMutai | JARID2 |
DMDMi | 61252601 |
Proteomic databases
EPDi | Q92833 |
jPOSTi | Q92833 |
MassIVEi | Q92833 |
MaxQBi | Q92833 |
PaxDbi | Q92833 |
PeptideAtlasi | Q92833 |
PRIDEi | Q92833 |
ProteomicsDBi | 6958 75511 [Q92833-1] 75512 [Q92833-2] |
Protocols and materials databases
Antibodypediai | 25028, 238 antibodies from 27 providers |
DNASUi | 3720 |
Genome annotation databases
Ensembli | ENST00000341776.7; ENSP00000341280.2; ENSG00000008083.14 ENST00000397311.4; ENSP00000380478.3; ENSG00000008083.14 [Q92833-3] |
GeneIDi | 3720 |
KEGGi | hsa:3720 |
MANE-Selecti | ENST00000341776.7; ENSP00000341280.2; NM_004973.4; NP_004964.2 |
UCSCi | uc003nbj.5, human [Q92833-1] |
Organism-specific databases
CTDi | 3720 |
DisGeNETi | 3720 |
GeneCardsi | JARID2 |
HGNCi | HGNC:6196, JARID2 |
HPAi | ENSG00000008083, Tissue enhanced (bone) |
MIMi | 601594, gene |
neXtProti | NX_Q92833 |
OpenTargetsi | ENSG00000008083 |
Orphaneti | 528084, Non-specific syndromic intellectual disability |
PharmGKBi | PA29995 |
VEuPathDBi | HostDB:ENSG00000008083 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1246, Eukaryota |
GeneTreei | ENSGT00940000159220 |
HOGENOMi | CLU_007086_0_0_1 |
InParanoidi | Q92833 |
OMAi | VFNGSNR |
OrthoDBi | 664180at2759 |
PhylomeDBi | Q92833 |
TreeFami | TF323264 |
Enzyme and pathway databases
PathwayCommonsi | Q92833 |
Reactomei | R-HSA-212300, PRC2 methylates histones and DNA |
SignaLinki | Q92833 |
SIGNORi | Q92833 |
Miscellaneous databases
BioGRID-ORCSi | 3720, 18 hits in 1115 CRISPR screens |
ChiTaRSi | JARID2, human |
GeneWikii | JARID2 |
GenomeRNAii | 3720 |
Pharosi | Q92833, Tbio |
PROi | PR:Q92833 |
RNActi | Q92833, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000008083, Expressed in secondary oocyte and 250 other tissues |
Genevisiblei | Q92833, HS |
Family and domain databases
Gene3Di | 1.10.150.60, 1 hit |
InterProi | View protein in InterPro IPR001606, ARID_dom IPR036431, ARID_dom_sf IPR003347, JmjC_dom IPR003349, JmjN IPR004198, Znf_C5HC2 |
Pfami | View protein in Pfam PF01388, ARID, 1 hit PF02373, JmjC, 1 hit PF02375, JmjN, 1 hit PF02928, zf-C5HC2, 1 hit |
SMARTi | View protein in SMART SM00501, BRIGHT, 1 hit SM00558, JmjC, 1 hit SM00545, JmjN, 1 hit |
SUPFAMi | SSF46774, SSF46774, 1 hit |
PROSITEi | View protein in PROSITE PS51011, ARID, 1 hit PS51184, JMJC, 1 hit PS51183, JMJN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | JARD2_HUMAN | |
Accessioni | Q92833Primary (citable) accession number: Q92833 Secondary accession number(s): A8K9Z6 Q86X63 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | March 15, 2005 | |
Last modified: | May 25, 2022 | |
This is version 184 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references